Publications
Weblinks to some publications are provided by clicking on the associated image. Please also see Google Scholar.
2023
Broumidis, E., Thomson, C. G., Gallagher, B., Sotorrios, L., McKendrick, K. G., Macgregor, S. A., Paterson, M. J., Lovett, J. E., Lloyd, G. O., Rosair, G. M., Kalogirou, P. A., Vilela, F. (2023) The Photochemical Mediated Ring Contraction of 4H-1,2,6-Thiadiazines To Afford 1,2,5-Thiadiazol-3(2H)-one 1-Oxides, Organic Letters, https://doi.org/10.1021/acs.orglett.3c02673
Shah, A., Taylor, M. J., Molinaro, G., Anbu, S., Verdu, M., Jennings, L., Mikulska, I., Diaz-Moreno, S., EL Mkami, H., Smith, G. M., Britton, M. M., Lovett, J. E., Peacock, A. F. A. (2023) Design of the elusive proteinaceous oxygen donor copper site suggests a promising future for copper for MRI contrast agents, Proc. Natl. Acad. Sci. (USA), 120, e2219036120.
Sowiński, M. P., Gahlawat, S., Lund, B. A., Warnke, A. L., Hopmann, K. H., Lovett, J. E., Haugland, M. M. (2023) Conformational tuning improves the stability of spirocyclic nitroxides with long paramagnetic relaxation times, Communications Chemistry 6, 111.
Shiny, M., Price, B. D., Wilson, C. B., Mukherjee, A., Starck, M., Parker, D., Wilson, M. Z., Lovett, J. E., Han, S., Sherwin, M. S. (2023) Triggered functional dynamics of AsLOV2 by time-resolved electron paramagnetic resonance at high magnetic fields. Angew. Chemie Int. Ed., e202212832.
2022
Stewart, A. M., Shanmugam, M., Kutta, R. J., Scrutton, N. S., Lovett, J. E., Hay, S. (2022) Combined Pulsed Electron Double Resonance EPR and Molecular Dynamics Investigations of Calmodulin Suggest Effects of Crowding Agents on Protein Structures. Biochemistry, 61, 1735-1742.
Russell, H., Cura, R., and Lovett, J. E. (2022) DEER data analysis software: a comparative guide. Frontiers in Molecular Biosciences, 9, 915167.
Keeley, J., Choudhury, T., Galazzo, L., Bordignon, E., Feintuch, A., Goldfarb, D., Russell, H., Taylor, M. J., Lovett, J. E., Eggeling, A., Fabregas Ibanez, L., Keller, K., Yulikov, M., Jeschke, G., and Kuprov, I. (2022) Neural networks in pulsed dipolar spectroscopy: A practical guide. J. Magn. Reson., 338, 107186.
2021
Starck, M and co-workers, (2021) Versatile para-substituted prince lanthanide coordination complexes allow late stage tailoring of complex function. Chemistry-A European Journal., 27, 17921-17927.
Schiemann, O and co-workers, (2021) Benchmark test and guidelines for DEER/PELDOR experiments on nitroxide-labeled molecules. J. Am. Chem. Soc., 143, 17875-17890.
Russell, H., Stewart, R., Prior, C., Oganesyan, V. S., Gaule, T. G., and Lovett, J. E., (2021) DEER and RIDME Measurements of the Nitroxide-Spin Labelled Copper-Bound Amine Oxidase Homodimer from Arthrobacter Globiformis. Applied Magnetic Resonance, Special Issue - Gareth Eaton: On the Occasion of his 80th Birthday, 52, 995-1021.
2020
EL Mkami, H., Hunter, R. I., Cruikshank, P. A. S., Taylor, M. J., Lovett, J. E., Feintuch, A., Qi, M., Godt, A., and Smith, G. M., (2020) High-sensitivity Gd(III)-Gd(III) EPR distance measurements that eliminate artefacts seen at short distances. Magnetic Resonance, 1, p. 301.
Cranford-Smith, T., Jamshad, M., Jeeves, M., Chandler, R. A., Yule, J., Robinson, A., Alam, F., Dunne, K. A., Aponte Angarita, E. H., Alanazi, M., Carter, C., Henderson, I. R., Lovett, J. E., Winn, P., Knowles, T., and Huber, D. (2020) Iron is a ligand of SecA-like metal-binding domains in vivo. Journal of Biological Chemistry, 295, 7516-7528.
Hardwick, J. S., Haugland, M. M., El-Sagheer, A. H., Ptchelkine, D., Beierlein, F. R., Lane, A. N., Brown, T., Lovett, J. E., and Anderson, E. A. (2020) 2'-alkynl spin-labelling is a minimally perturbing tool for DNA structural analysis. Nucleic Acids Research, 48, p. 2830.
2019
Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G. M., Parker, D. and Lovett, J. E., (2019) A Gadolinium Spin Label with Both a Narrow Central Transition and Short Tether for use in Double Electron Electron Resonance Distance Measurements. Inorg. Chem. 58, p. 3015.
Corey, R. A., Ahdash, Z., Shah, A., Pyle, E., Allen, W. J., Fessl, T., Lovett, J. E., Politis, A. and Collinson, I., (2019) ATP-induced asymmetric pre-protein folding as a driver of protein translocation through the Sec machinery. eLife 8 e41803.
2018
Gil-Ramirez, G., Shah, A., El Mkami, H., Porfyrakis, K., Briggs, G. A. D., Morton, J. J. L., Anderson, H. L. and Lovett, J. E., (2018) Distance Measurement of a Non-covalently Bound Y@C82 Pair with Double Electron Electron Resonance Spectroscopy. J. Am. Chem. Soc. 140 p. 7420.
Bowen, A. M., Johnson, E. O. D., Mercuri, F., Hoskins, N. J., Qiao, R., McCullagh, J. S. O., Lovett, J. E., Bell, S. G., Zhou, W., Timmel, C. R. Wong, L. L. and Harmer, J. R., (2018) A Structural Model of a P450-Ferredoxin Complex from Orientation-Selective Double Electron-Electron Resonance Spectroscopy. J. Am. Chem. Soc. 140 p. 2514.
Haugland, M. M, Lovett, J. E., Anderson, E. A., (2018) Advances in the synthesis of nitroxide radicals for use in biomolecule spin labelling. Chem. Soc. Rev. 47 p. 668
2017
Drummond, N. J., Davies, N. O., Lovett, J. E., Miller, M. R., Cook, G., Becker, T., Becker, C. G., McPhail, D. B., Kunath, T., (2017) A synthetic cell permeable antioxidant protects neurons against acute oxidative stress, Scientific Reports 7, Article number 11857. News on the CRM website.
Motion, C. L., Cassidy, S. L., Cruickshank, P. A. S., Hunter, R. I., Bolton, D. R., El Mkami, H., Van Doorslaer, S., Lovett, J. E., Smith, G. M., (2017) The use of composite pulses for improving DEER signal at 94 GHz, J. Magn. Reson. 278 p. 122.
2016
Haugland, M. M, Anderson, E. A., Lovett, J. E., (2016) Tuning the properties of nitroxide spin labels for use in electron paramagnetic resonance spectroscopy through chemical modification of the nitroxide framework. Electron Paramagnetic Resonance - Volume 25 Editors: Victor Chechik and Damien M Murphy Download a copy here.
Haugland, M. M., El-Sagheer, A. H., Porter, R. J., Pena, J., Brown, T., Anderson, E. A., Lovett, J. E., (2016) 2’-Alkynylnucleotides: A Sequence- and Spin Label-Flexible Strategy for EPR Spectroscopy in DNA. J. Am. Chem. Soc. 138 p. 9069. Download a copy here.
Hajjaj, B., Shah, A., Bell, S., Shirran, S. L., Botting, C. H., Slawin, A. M. Z., Hulme, A. N., Lovett, J. E., (2016) Synthesis of Next-Generation Maleimide Radical Labels. SynLett. 27 p. 2357. Download a copy here.
Motion, C. L., Lovett, J. E., Bell, S., Cassidy, S. L., Cruickshank, P. A. S., Bolton, D. R., Hunter, R. I., El Mkami, H., Van Doorslaer, S., Smith, G. M., (2016) DEER Sensitivity between Iron Centers and Nitroxides in Heme-Containing Proteins Improves Dramatically Using Broadband High-Field EPR. J. Phys. Chem. Lett. 7 p. 1411.
Bowen, A. M., Jones, M. W., Lovett, J. E., Gaule, T. G., McPherson, M. J., Dilworth, J. R., Timmel, C. R. and Harmer, J. R., (2016) Exploiting orientation-selective DEER: determining molecular structure in systems containing Cu(II) centres. Phys. Chem. Chem. Phys. 18 p. 5981.
Download Stacey Bell’s PhD thesis.
2010-2015
Lovett, J. E., Abbott, R. J. M., Roversi, P., Johnson, S., Caesar, J. J. E., Doria, M., Jeschke, G., Timmel, C. R., Lea S. M., (2013) Investigating the structure of the factor B vWF-A domain/CD55 protein-protein complex using DEER spectroscopy: successes and pitfalls. Mol. Phys. 111 2865-2872
Lovett, J. E., Lovett, B. W., Harmer, J., (2012) DEER-Stitch: Combining three- and four-pulse DEER measurements for high sensitivity, deadtime free data. J. Magn. Reson. 223 98-106
Orwick-Rydmark, M., Lovett, J. E., Graziadei, A., Lindholm, L., Hicks, M. R., Watts, A., (2012) Detergent-free incorporation of a seven-transmembrane receptor protein into nanosized bilayer lipodisq particles for functional and biophysical studies. Nano Lett. 12 4687-4692
De la Mora, E., Lovett, J. E., Blanford, C. F., Garman, E. F., Valderrama, B., Rudiño-Piñera, E., (2012) Structural changes caused by radiation induced reduction and radiolysis: the effect of X-ray absorbed dose in a fungal multicopper oxidase. Acta Cryst. D 68, 564-577
Ramachandran, P. L., Lovett, J. E., Carl, P. J., Cammarata, M., Lee, J. H., Jung, Y. O., Ihee, H., Timmel, C. R., van Thor, J. J., (2011) The short-lived signaling state of the Photoactive Yellow Protein photoreceptor revealed by combined structural probes. J. Am. Chem. Soc., 133, 9395-9404
Lillington, J. E. D., Lovett, J. E., Johnson, S., Roversi, P., Timmel, C. R., Lea, S. M., (2011) Shigella flexineri Spa15 crystal structure verified in solution by double electron electron resonance. J. Mol. Biol. 405, 427-435
pre 2010
Lovett, J. E., Hoffmann, M., Cnossen, A., Shutter, A. T. J., Hogben, H. J., Warren, J. E., Pascu, S. I., Kay, C. W. M., Timmel, C. R., Anderson, H. L., (2009) Probing flexibility in porphyrin-based molecular wires using double electron electron resonance. J. Am. Chem. Soc. 131, 13852–13859
Lovett, J. E., Bowen, A. M., Timmel, C. R., Jones, M. W., Dilworth, J. R., Caprotti, D., Bell, S.G., Wong, L. L., Harmer, J., (2009) Structural information from orientationally selective DEER spectroscopy. Phys. Chem. Chem. Phys. 11, 6840-6848
Schneider, M. C., Prosser, B. E., Caesar, J. J. E., Kugelberg, E., Li, S., Quoraishi, S., Lovett, J. E., Deane, J. E., Sim, R. B., Roversi, P., Johnson, S., Tang, C. M., Lea, S. M., (2009) Neisseria meningitidis recruits factor H using protein mimicry of host carbohydrates. Nature 458, 890-893
Barry, E. R., Lovett, J. E., Costa, A., Lea S. M., Bell S. D., (2009) Intersubunit allosteric communication mediated by a conserved loop in the MCM helicase. Proc. Natl. Acad. Sci. 106, 1051-1056
Banham, J. E., Baker, C. M., Ceola, S., Day, I. J., Grant, G. H., Groenen, E. J. J., Rodgers, C. T., Jeschke, G., Timmel, C. R., (2008) Distance measurements in the borderline region of applicability of CW EPR and DEER: A model study on a homologous series of spin-labelled peptides. J. Magn. Reson. 191, 202-218
Banham, J. E., Jeschke, G., Timmel, C. R., (2007) Evidence from EPR that nitroxide spin labels attached to human hemoglobin alter their conformation upon freezing. Mol. Phys. 105, 2041-2047.
Jeschke, G., Chechik, V., Ionita, P., Godt, A., Zimmermann, H., Banham, J., Timmel, C. R., Hilger, D., Jung, H., (2006) DeerAnalysis2006-a comprehensive software package for analyzing pulsed ELDOR data. Appl. Magn. Reson. 30, 473-498
Banham, J. E., Timmel, C. R., Abbott, R. J. M., Lea, S. M., Jeschke, G., (2006) The characterization of weak protein-protein interactions: Evidence from DEER for the trimerization of a von Willebrand factor A domain in solution. Angew. Chem. Int. Ed. 45, 1058-1061