Dr Sabine Gruschow

Research Fellow

Researcher profile

Email

sg200@st-andrews.ac.uk

 

Selected publications

• Open access

  CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23

  Grüschow, S., McQuarrie, S., Ackermann, K., McMahon, S., Bode, B., Gloster, T. & White, M., 12 Apr 2024, In: Nucleic Acids Research. 52, 6, p. 2761-2775 15 p., gkae167.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Antiviral type III CRISPR signalling via conjugation of ATP and SAM

  Chi, H., Hoikkala, V. P., Gruschow, S., Graham, S., Shirran, S. L. & White, M., 26 Oct 2023, In: Nature. 622, 7984, p. 826-833 22 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Author Correction: Cyclic nucleotide-induced helical structure activates a TIR immune effector (Nature, (2022), 608, 7924, (808-812), 10.1038/s41586-022-05070-9)

  Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L. & White, M. F., 2 Feb 2023, In: Nature. 614, 7946, p. E15

  Research output: Contribution to journal › Comment/debate › peer-review

• Open access

  Cyclic nucleotide-induced helical structure activates a TIR immune effector

  Hogrel, G., Guild, A., Graham, S., Rickman, H., Grüschow, S., Bertrand, Q., Spagnolo, L. & White, M. F., 25 Aug 2022, In: Nature. 608, 7924, p. 808–812 5 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Specificity and sensitivity of an RNA targeting type III CRISPR complex coupled with a NucC endonuclease effector

  Grüschow, S., Adamson, C. S. & White, M. F., 16 Dec 2021, In: Nucleic Acids Research. 49, 22, p. 13122-13134 13 p., gkab1190.

  Research output: Contribution to journal › Article › peer-review

• Open access

  The CRISPR ancillary effector Can2 is a dual-specificity nuclease potentiating type III CRISPR defence

  Zhu, W., McQuarrie, S. J., Gruschow, S., McMahon, S., Graham, S., Gloster, T. & White, M., 18 Mar 2021, In: Nucleic Acids Research. 49, 5, p. 2777–2789 13 p., gkab073.

  Research output: Contribution to journal › Article › peer-review

• Open access

  An anti-CRISPR viral ring nuclease subverts type III CRISPR immunity

  Athukoralage, J. S., McMahon, S., Zhang, C., Gruschow, S., Graham, S., Krupovic, M., Whitaker, R., Gloster, T. & White, M., 23 Jan 2020, In: Nature. 577, 7791, p. 572-575 19 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Phenylalanine meta-hydroxylase: a single residue mediates mechanistic control of aromatic amino acid hydroxylation

  Gruschow, S., Sadler, J., Sharrat, P. & Goss, R. J. M., 3 Feb 2020, In: ChemBioChem. 21, 3, p. 417-422

  Research output: Contribution to journal › Article › peer-review

• Open access

  Regulation of the RNA and DNA nuclease activities required for Pyrococcus furiosus Type III-B CRISPR-Cas immunity

  Foster, K., Grüschow, S., Bailey, S., White, M. F. & Terns, M. P., 7 May 2020, In: Nucleic Acids Research. 48, 8, p. 4418-4434 17 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Tetramerisation of the CRISPR ring nuclease Crn3/Csx3 facilitates cyclic oligoadenylate cleavage

  Athukoralage, J. S., McQuarrie, S. J., Gruschow, S., Graham, S., Gloster, T. & White, M., 20 Jul 2020, In: eLife. 9, 19 p., e57627.

  Research output: Contribution to journal › Article › peer-review

 

See more publications