Dr Clarissa Melo Czekster
Reader
PhD supervision
- Soumili Biswas
- Qingtian Gong
- Ghazal Sharifian
- Claire Stevens
Selected publications
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Open access
Broad substrate scope C-C oxidation in cyclodipeptides catalysed by a flavin-dependent filament
Sutherland, E., Harding, C. J., du Monceau de Bergendal, T., Florence, G. J., Ackermann, K., Bode, B. E., Synowsky, S., Sundaramoorthy, R. & Melo Czekster, C., 24 Jan 2025, In: Nature Communications. 16, 14 p., 995.Research output: Contribution to journal › Article › peer-review
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Design of an antimicrobial peptide prodrug of D-Bac8C: activation and growth inhibition of Pseudomonas aeruginosa
Gong, Q. & Melo Czekster, C., 27 Aug 2025. 1 p.Research output: Contribution to conference › Poster
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Open access
Immobilized nucleoside 2-deoxyribosyltransferases from extremophiles for nucleoside biocatalysis
Hernández Martínez, S., Tang, P., Parra-Saldivar, R., Melchor-Martínez, E. & Melo Czekster, C., 14 Jan 2025, In: ACS Omega. 10, 1, p. 1067-1076 10 p.Research output: Contribution to journal › Article › peer-review
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Open access
Improved nucleoside (2'-deoxy)ribosyltransferases maximize enzyme promiscuity while maintaining catalytic efficiency
Tang, P., Zickuhr, G. M., Dickson, A. L., Harding, C. J., Devi, S., Lebl, T., Harrison, D. J., da Silva, R. G. & Melo Czekster, C., 21 Nov 2025, In: ACS Chemical Biology. 20, 11, p. 2547–2553 7 p.Research output: Contribution to journal › Letter › peer-review
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Open access
Closing the loop: the “Antibiotics under our feet” project
Ross, K. S., Melo Czekster, C. & Cornwell, R. M., 9 Aug 2024. 1 p.Research output: Contribution to conference › Poster › peer-review
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Open access
Defining the mode of action of cisplatin combined with NUC-1031, a phosphoramidate modification of gemcitabine
Patel, D., Dickson, A., Zickuhr, G. M., Um, I. H., Read, O. J., Melo Czekster, C., Mullen, P., Harrison, D. J. & Bre, J. L., 1 Dec 2024, In: Translational Oncology. 50, 11 p., 102114.Research output: Contribution to journal › Article › peer-review
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Open access
Snapshots of the reaction coordinate of a thermophilic 2'-deoxyribonucleoside/ribonucleoside transferase
Tang, P., Harding, C. J., Dickson, A., da Silva, R. G., Harrison, D. J. & Melo Czekster, C., 1 Mar 2024, In: ACS Catalysis. 14, 5, p. 3090-3102 13 p.Research output: Contribution to journal › Article › peer-review
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Open access
The immobilization of a cyclodipeptide synthase enables biocatalysis for cyclodipeptide production
Alvarado-Ramirez, L., Sutherland, E. J., Melchor-Martinez, E., Parra-Saldivar, R., Bonaccorso, A. D. & Melo Czekster, C., 2 Sept 2024, In: ACS Sustainable Chemistry & Engineering. 12, 35, p. 13080-13089 10 p.Research output: Contribution to journal › Article › peer-review
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Open access
Unearthing new learning opportunities: adapting and innovating through the 'Antibiotics Under Our Feet' citizen science project in Scotland during COVID-19
Cornwell, R. M., Ross, K. S., Gibeily, C., Guthrie, I., Li, P. H., Seeley, L. T., Kong, Y., True, A., Barnes, A., Nimmo, E., Len, G., Oprea, I., Lin, B., Sasi, A., Chu, V., Davidson, C., Ulasavets, D., Renouf-Bilanski, G., Dmitrieva, M. & Leung, Y. & 9 others, , 19 Jun 2024, In: Access Microbiology. 6, 6, 13 p., acmi000710.v3.Research output: Contribution to journal › Article › peer-review
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Open access
An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa
Harding, C. J., Bischoff, M., Bergkessel, M. & Melo Czekster, C., 1 Sept 2023, In: Nature Chemical Biology. 19, 9, p. 1158-1166 15 p.Research output: Contribution to journal › Article › peer-review