Dr Hassane El Mkami

Senior Research Fellow

Researcher profile

Phone

+44 (0)1334 46 3029

Phone

+44 (0)1334 46 3062

Email

hem2@st-andrews.ac.uk

 

Selected publications

• Open access

  Investigating native metal ion binding sites in mammalian histidine-rich glycoprotein

  Ackermann, K., Khazaipoul, S., Wort, J., Sobczak, A. I. S., El Mkami, H., Stewart, A. J. & Bode, B. E., 17 Mar 2023, (Accepted/In press) In: Journal of the American Chemical Society.

  Research output: Contribution to journal › Article › peer-review

• Open access

  HDX-guided EPR spectroscopy to interrogate membrane protein dynamics

  Lane, B. J., Wang, B., Ma, Y., Calabrese, A. N., El Mkami, H. & Pliotas, C., 16 Sep 2022, In: STAR Protocols. 3, 3, 28 p., 101562.

  Research output: Contribution to journal › Review article › peer-review

• Open access

  Pocket delipidation induced by membrane tension or modification leads to a structurally analogous mechanosensitive channel state

  Wang, B., Lane, B. J., Kapsalis, C., Ault, J. R., Sobott, F., El Mkami, H., Calabrese, A. N., Kalli, A. C. & Pliotas, C., 7 Apr 2022, In: Structure. 30, 4, p. 608-622.e5 21 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  High-sensitivity Gd³⁺-Gd³⁺ EPR distance measurements that eliminate artefacts seen at short distances

  El Mkami, H., Hunter, R. I., Cruickshank, P. A. S., Taylor, M. J., Lovett, J. E., Feintuch, A., Qi, M., Godt, A. & Smith, G. M., 9 Dec 2020, In: Magnetic Resonance. 1, 2, p. 301-313

  Research output: Contribution to journal › Article › peer-review

• Open access

  A gadolinium spin label with both a narrow central transition and short tether for use in double electron electron resonance distance measurements

  Shah, A., Roux, A., Starck, M., Mosely, J. A., Stevens, M., Norman, D. G., Hunter, R. I., El Mkami, H., Smith, G., Parker, D. & Lovett, J. E., 18 Feb 2019, (E-pub ahead of print) In: Inorganic Chemistry. Article ASAP

  Research output: Contribution to journal › Article › peer-review

• Open access

  Allosteric activation of an ion channel triggered by modification of mechanosensitive nano-pockets

  Kapsalis, C., Wang, B., El Mkami, H., Pitt, S. J., Schnell, J., Smith, T. K., Lippiat, J., Bode, B. E. & Pliotas, C., 10 Oct 2019, In: Nature Communications. 10, 14 p., 4619.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Distance measurement of a noncovalently bound Y@C₈₂ Pair with double electron electron resonance spectroscopy

  Gil-Ramírez, G., Shah, A., El Mkami, H., Porfyrakis, K., Briggs, A. D., Morton, J. J. L., Anderson, H. L. & Lovett, J. E., 20 Jun 2018, In: Journal of the American Chemical Society. 140, 24, p. 7420-7424

  Research output: Contribution to journal › Article › peer-review

• Open access

  Structure of the chromatin remodelling enzyme Chd1 bound to a ubiquitinylated nucleosome

  Sundaramoorthy, R., Hughes, A. L., El-Mkami, H., Norman, D. G., Ferreira, H. & Owen-Hughes, T., 6 Aug 2018, In: eLife. 7, 28 p., e35720.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Cryo-EM structure of a relaxase reveals the molecular basis of DNA unwinding during bacterial conjugation

  Ilangovan, A., Kay, C. W. M., Roier, S., El Mkami, H., Salvadori, E., Zechner, E. L., Zanetti, G. & Waksman, G., 4 May 2017, In: Cell. 169, 4, p. 708-721 27 p., e12.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Structural reorganization of the chromatin remodeling enzyme Chd1 upon engagement with nucleosomes

  Sundaramoorthy, R., Hughes, A. L., Singh, V., Wiechens, N., Ryan, D. P., El-Mkami, H., Petoukhov, M., Svergun, D. I., Treutlein, B., Quack, S., Fischer, M., Michaelis, J., Böttcher, B., Norman, D. G. & Owen-Hughes, T., 23 Mar 2017, In: eLife. 6, 28 p., e22510.

  Research output: Contribution to journal › Article › peer-review

 

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