Dr Remi Fritzen

Research Fellow

Researcher profile

Email

rf79@st-andrews.ac.uk

 

Research areas

I am a postdoc in Alan Stewart's group. I am using fluorescence to assess the effect of zinc and other factor on insulin hexamers assembly and disassembly.

PhD supervision

• Boyang Lin

Selected publications

• Open access

  Targeted removal of the FA2 site on human albumin prevents fatty acid-mediated inhibition of Zn²⁺-binding

  Wu, D., Hierons, S. J., Polepalli, S., Gucwa, M., Fritzen, R., Markiewicz, M., Sabín, J., Minor, W., Murzyn, K., Blindauer, C. A. & Stewart, A. J., 1 Jun 2024, In: Journal of Lipid Research. 65, 6, 12 p., 100560.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Magnesium deficiency and cardiometabolic disease

  Fritzen, R., Davies, A., Veenhuizen, M., Campbell, M., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., 17 May 2023, In: Nutrients. 15, 10, 19 p., 2355.

  Research output: Contribution to journal › Review article › peer-review

• Open access

  Structural and biochemical characterisation of Co²⁺-binding sites on serum albumins and their interplay with fatty acids

  Wu, D., Gucwa, M., Czub, M. P., Cooper, D. R., Shabalin, I. G., Fritzen, R., Arya, S., Schwarz-Linek, U., Blindauer, C. A., Minor, W. & Stewart, A. J., 21 Jun 2023, In: Chemical Science. 14, 23, p. 6244-6258 15 p.

  Research output: Contribution to journal › Article › peer-review

• T-independent responses to polysaccharides in humans mobilize marginal zone B cells prediversified against gut bacterial antigens

  Weller, S., Sterlin, D., Fadeev, T., Coignard, E., Aires, A. V. D. L., Goetz, C., Fritzen, R., Bahuaud, M., Batteux, F., Gorochov, G., Weill, J.-C. & Reynaud, C.-A., 27 Jan 2023, In: Science Immunology. 8, 79, 18 p., eade1413.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Critical role of WASp in germinal center tolerance through regulation of B cell apoptosis and diversification

  Descatoire, M., Fritzen, R., Rotman, S., Kuntzelman, G., Leber, X. C., Droz-Georget, S., Thrasher, A. J., Traggiai, E. & Candotti, F., 8 Mar 2022, In: Cell Reports. 38, 10, 17 p., 110474.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Strategies for therapeutic amelioration of aberrant plasma Zn²⁺ handling in thrombotic disease: targeting fatty acid/serum albumin-mediated effects

  Regan-Smith, S., Fritzen, R., Hierons, S. J., Ajjan, R. A., Blindauer, C. A. & Stewart, A. J., 7 Sept 2022, In: International Journal of Molecular Sciences. 23, 18, 18 p., 10302.

  Research output: Contribution to journal › Review article › peer-review

• Open access

  Asymmetric base-pair opening drives helicase unwinding dynamics

  Colizzi, F., Perez-Gonzalez, C., Fritzen, R., Levy, Y., White, M. F., Penedo, J. C. & Bussi, G., 5 Nov 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 45, p. 22471-22477 7 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses

  Le Gallou, S., Zhou, Z., Thai, L.-H., Fritzen, R., de Los Aires, A. V., Mégret, J., Yu, P., Kitamura, D., Bille, E., Tros, F., Nassif, X., Charbit, A., Weller, S., Weill, J.-C. & Reynaud, C.-A., Aug 2018, In: Journal of Experimental Medicine. 215, 8, p. 2035-2053 19 p.

  Research output: Contribution to journal › Article › peer-review

• A single aspartate mutation in the conserved catalytic site of Rev3L generates a hypomorphic phenotype in vivo and in vitro

  Fritzen, R., Delbos, F., De Smet, A., Palancade, B., Canman, C. E., Aoufouchi, S., Weill, J.-C., Reynaud, C.-A. & Storck, S., Oct 2016, In: DNA Repair. 46, p. 37-46 10 p.

  Research output: Contribution to journal › Article › peer-review

• Segmented filamentous bacterium uses secondary and tertiary lymphoid tissues to induce gut IgA and specific T helper 17 cell responses

  Lécuyer, E., Rakotobe, S., Lengliné-Garnier, H., Lebreton, C., Picard, M., Juste, C., Fritzen, R., Eberl, G., McCoy, K. D., Macpherson, A. J., Reynaud, C.-A., Cerf-Bensussan, N. & Gaboriau-Routhiau, V., 17 Apr 2014, In: Genes and Immunity. 40, 4, p. 608-20 13 p.

  Research output: Contribution to journal › Article › peer-review

 

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