Prof David Crossman
Dean of Medicine
Professor
Selected publications
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Open access
Effect of second booster vaccinations and prior infection against SARS-CoV-2 in the UK SIREN healthcare worker cohort
Kirwan, P. D., Hall, V. J., Foulkes, S., Otter, A. D., Munro, K., Sparkes, D., Howells, A., Platt, N., Broad, J., Crossman, D., Norman, C., Corrigan, D., Jackson, C. H., Cole, M., Brown, C. S., Atti, A., Islam, J., SIREN Study Group, Presanis, A. M. & Charlett, A. & 2 others, , Jan 2024, In: The Lancet Regional Health - Europe. 36, 12 p., 100809.Research output: Contribution to journal › Article › peer-review
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Open access
Effect of transcatheter aortic valve implantation vs surgical aortic valve replacement on all-cause mortality in patients with aortic stenosis: a randomized clinical trial
UK TAVI Trial Investigators, 17 May 2022, In: JAMA - Journal of the American Medical Association. 327, 19, p. 1875-1887 13 p.Research output: Contribution to journal › Article › peer-review
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Open access
A therapeutic antibody targeting osteoprotegerin attenuates severe experimental pulmonary arterial hypertension
Arnold, N. D., Pickworth, J. A., West, L. E., Dawson, S., Carvalho, J. A., Casbolt, H., Braithwaite, A. T., Iremonger, J., Renshall, L., Germaschewski, V., McCourt, M., Bland-Ward, P., Kowash, H., Hameed, A. G., Rothman, A. M. K., Frid, M. G., Roger Thompson, A. A., Evans, H. R., Southwood, M. & Morrell, N. W. & 7 others, , 15 Nov 2019, In: Nature Communications. 10, 18 p., 5183.Research output: Contribution to journal › Article › peer-review
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Open access
Irbesartan in Marfan syndrome (AIMS): a double-blind, placebo-controlled randomised trial
Mullen, M., Jin, X. Y., Child, A., Stuart, A. G., Dodd, M., Aragon-Martin, J. A., Gaze, D., Kiotsekoglou, A., Yuan, L., Hu, J., Foley, C., Van Dyck, L., Knight, R., Clayton, T., Swan, L., Thomson, J. D. R., Erdem, G., Crossman, D., Flather, M. & AIMS Investigators, 21 Dec 2019, In: Lancet. 394, 10216, p. 2263-2270Research output: Contribution to journal › Article › peer-review
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Open access
ATP evokes Ca2+ responses and CXCL5 secretion via P2X4 receptor activation in human monocyte-derived macrophages
Layhadi, J. A., Turner, J., Crossman, D. & Fountain, S. J., 1 Feb 2018, In: The Journal of Immunology. 200, 3, p. 1159-1168Research output: Contribution to journal › Article › peer-review
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Canakinumab for atherosclerotic disease
MRC-ILA Heart investigators, Rothman, A. M., Morton, A. C. & Crossman, D. C., 11 Jan 2018, In: New England Journal of Medicine. 378, 2, p. 197-8 2 p.Research output: Contribution to journal › Article › peer-review
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Open access
Dietary docosahexaenoic acid reduces oscillatory wall shear stress, atherosclerosis and hypertension, most likely mediated via an IL-1-mediated mechanism
Alfaida, M., Chamberlain, J., Rothman, A., Crossman, D. C., Villa-Uriol, M.-C., Hadoke, P., Wu, J., Schenkel, T., Evans, P. & Francis, S., 3 Jul 2018, In: Journal of the American Heart Association. 7, 13, 19 p., e008757.Research output: Contribution to journal › Article › peer-review
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Interleukin-1 beta inhibition with canakinumab and reducing lung cancer-subset analysis of the canakinumab anti-inflammatory thrombosis outcome study trial (CANTOS)
Crossman, D. & Rothman, A. M. K., 18 Sept 2018, In: Journal of Thoracic Disease. 10, Suppl 26, p. S3084-S3087Research output: Contribution to journal › Editorial › peer-review
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Open access
The Canakinumab Antiinflammatory Thrombosis Outcome Study trial-the starting gun has fired
Crossman, D. & Rothman, A., Dec 2017, In: Journal of Thoracic Disease. 9, 12, p. 4922-4925 4 p.Research output: Contribution to journal › Editorial › peer-review
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Anti-inflammatory therapies in myocardial infarction
Abbate, A., Morton, A. C. & Crossman, D. C., 27 Jun 2015, In: Lancet. 385, 9987, p. 2573-2574 2 p.Research output: Contribution to journal › Letter › peer-review