Dr Clarissa Melo Czekster
Sir Henry Dale Fellow and Lecturer
PhD supervision
- Charlene Ogilvie
- Ngoc Anh Thu Trinh
- Martha Simpson
- Qingtian Gong
Selected publications
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Open access
Snapshots of the reaction coordinate of a thermophilic 2'-deoxyribonucleoside/ribonucleoside transferase
Tang, P., Harding, C. J., Dickson, A., da Silva, R. G., Harrison, D. J. & Melo Czekster, C., 1 Mar 2024, In: ACS Catalysis. 14, 5, p. 3090-3102 13 p.Research output: Contribution to journal › Article › peer-review
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Open access
Unearthing new learning opportunities: adapting and innovating through the 'Antibiotics Under Our Feet' citizen science project in Scotland during COVID-19
Cornwell, R. M., Ross, K. S., Gibeily, C., Guthrie, I., Seeley, L. T., Kong, Y., True, A., Barnes, A., Nimmo, E., Len, G., Oprea, I., Lin, B., Sasi, A., Chu, V., Davidson, C., Ulasavets, D., Renouf-Bilanski, G., Dmitrieva, M., Leung, Y., Ye, Z., & 7 others , 7 Mar 2024, (Accepted/In press) In: Access Microbiology.Research output: Contribution to journal › Article › peer-review
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Open access
An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa
Harding, C. J., Bischoff, M., Bergkessel, M. & Melo Czekster, C., 1 Sept 2023, In: Nature Chemical Biology. 19, 9, p. 1158-1166 15 p.Research output: Contribution to journal › Article › peer-review
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Open access
Antibiotics under our feet
Cornwell, R. M., Melo Czekster, C., Gibeily, C., Ionescu, D., Harper, S., Kennedy, M., Sutherland, E. J., Simpson, M. C., Easton, E., Vaughan, R., Jones, C. E., Lynch, R., Yong, E., Athukoralage, J. S., Hogrel, G., Zickuhr, G. M., Hynes, J., Williams, R-J., Ross, K. S., Kruger, L., & 9 others , 25 Apr 2023, Antibiotics under our feet.Research output: Other contribution
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Open access
Catalytic cycle of the bifunctional enzyme phosphoribosyl-ATP pyrophosphohydrolase/phosphoribosyl-AMP cyclohydrolase
Fisher, G., Pecaver, E., Read, B., Leese, S., Laing, E., Dickson, A., Melo Czekster, C. & da Silva, R. G., 2 Jun 2023, In: ACS Catalysis. 13, 11, p. 7669-7679 11 p.Research output: Contribution to journal › Article › peer-review
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Open access
Cyclic dipeptides and the human microbiome: opportunities and challenges
Ogilvie, C. E. & Melo Czekster, C., 15 Jul 2023, In: Bioorganic & Medicinal Chemistry. 90, 6 p., 117372.Research output: Contribution to journal › Review article › peer-review
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Open access
The novel anti-cancer fluoropyrimidine NUC-3373 is a potent inhibitor of thymidylate synthase and an effective DNA-damaging agent
Bré, J. L., Dickson, A., Read, O. J., Zhang, Y., McKissock, F. G., Mullen, P., Tang, P., Zickuhr, G. M., Melo Czekster, C. & Harrison, D. J., 31 Mar 2023, In: Cancer Chemotherapy and Pharmacology. 12 p.Research output: Contribution to journal › Article › peer-review
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Open access
Unveiling the catalytic mechanism of a processive metalloaminopeptidase
Simpson, M. C., Harding, C. J., Czekster, R., Remmel, L., Bode, B. E. & Melo Czekster, C., 4 Nov 2023, (E-pub ahead of print) In: Biochemistry. Articles ASAP, 18 p.Research output: Contribution to journal › Article › peer-review
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Open access
Active site remodelling of a cyclodipeptide synthase redefines substrate scope
Sutherland, E., Harding, C. J. & Melo Czekster, C., 25 Aug 2022, In: Communications Chemistry. 5, 1, 10 p., 101.Research output: Contribution to journal › Article › peer-review
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Open access
Structure, dynamics, and molecular inhibition of the Staphylococcus aureus m1A22-tRNA methyltransferase TrmK
Sweeney, P., Galliford, A., Kumar, A., Raju, D., Krishna, N. B., Sutherland, E., Leo, C. J., Fisher, G., Lalitha, R., Muthuraj, L., Sigamani, G., Oehler, V., Synowsky, S. A., Shirran, S. L., Gloster, T., Melo Czekster, C., Kumar, P. & da Silva, R. G., May 2022, In: Journal of Biological Chemistry. 298, 6, 15 p., 102040.Research output: Contribution to journal › Article › peer-review