Prof Matthew Holden

Prof Matthew Holden

Director of Impact

Professor

Researcher profile

Phone
+44 (0)1334 46 3504
Email
mtgh@st-andrews.ac.uk

 

Research areas

I am a molecular microbiologist and computer biologist with an interest in pathogenomics and the application of genomics in public health. I have over 24 years’ experience in bacterial whole genome sequencing (WGS), 13 of which were as a member of Pathogen Sequencing Unit at The Wellcome Trust Sanger Institute, responsible for sequencing and analysis of the genomes of a wide range of microbial pathogens. Since moving to the University of St Andrews in 2013, I have established a translational genomics research group working closely with academic, NHS and public health partners. My work has focused on using WGS as a research tool to investigate the evolution of pathogens and their ability to cause disease, and also as a clinical tool to identify outbreaks and trace the spread of infectious diseases. I have acted as the genomics lead for the CSO funded SHAIPI consortium tackling nosocomial infections in Scotland and led NIHR funded HATUA and CARE consortia investigating the burden and drivers of antibacterial resistance (ABR) and impact of COVID-19 on ABR in East Africa.

PhD supervision

  • Sepideh Benvari
  • Ashley Deventer
  • Jianbin Zhao
  • Eva Agnes Laker Odongpiny
  • Madeleine Clarkson

Selected publications

 

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