Dr Marco Ferreira Fernandes

Bioinformatician

Phone: +44 (0)1334 46 4229
Email: maff1@st-andrews.ac.uk

Research areas

PostDoc Supervision

Víctor Velasco-Pardo

Project title: Prediction of Brain Amyloid Positivity from Blood-based Biomarkers to Accelerate Alzheimer’s Disease Clinical Research

29/02/24 → 28/03/25

PhD Supervision

Hasnain Ahmed

Project title: Assessment of the predictive value of plasma proteins in oesophageal adenocarcinoma treatment

2/08/24 → 26/10/25

MSc Supervision

Bruin Snow

Project title: Predicting Biomarkers of Differential Accelerated Brain Aging between Patients with Alzheimer's Disease

26/05/25 → 12/08/25

Ece Sagiroglu

Project title: Multi-OMICs Data Integration for Alzheimer's Disease Prediction

26/05/25 → 12/08/25

BSc (Honours) Supervision

Sukannya Sarwar

Project title: Does insulin resistance change the rate of Alzheimer’s Disease progression?

03/02/24 → 16/04/25

Selected publications

Open access
Genome-wide association neural networks identify genes linked to family history of Alzheimer's disease
Ghose, U., Sproviero, W., Winchester, L., Amin, N., Zhu, T., Newby, D., Ulm, B. S., Papathanasiou, A., Shi, L., Liu, Q., Fernandes, M., Adams, C., Albukhari, A., Almansouri, M., Choudhry, H., van Duijn, C. & Nevado-Holgado, A., 8 Jan 2025, In: Briefings in Bioinformatics. 26, 1, 10 p., bbae704.
Research output: Contribution to journal › Article › peer-review
Open access
Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer’s disease
Amin, N., Liu, J., Sproviero, W., Arnold, M., Batra, R., Bonnechere, B., Chiou, Y.-J., Fernandes, M., Krumsiek, J., Newby, D., Nho, K., Kim, J. P., Saykin, A. J., Shi, L., Winchester, L. M., Yang, Y., Nevado-Holgado, A. J., Kastenmüller, G., Kaddurah-Daouk, R. & van Duijn, C. M., Dec 2025, In: Translational Psychiatry. 15, p. 1-15 15 p., 460.
Research output: Contribution to journal › Article › peer-review
Open access
Quantitative proteomics identifies plasma protein alterations that associate with metabolic and thrombotic profile changes after bariatric surgery
Ahmed, H., Fernandes, M. F., Abbas, K., Synowsky, S. A., Shirran, S. L., Ajjan, R. A. & Stewart, A. J., May 2025, In: Diabetes, Obesity and Metabolism. 27, 5, p. 2647-2657 11 p.
Research output: Contribution to journal › Article › peer-review
Interplay of metabolome and gut microbiome in individuals with major depressive disorder vs control individuals
Amin, N., Liu, J., Bonnechere, B., Mahmoudiandehkordi, S., Arnold, M., Batra, R., Chiou, Y. J., Fernandes, M., Ikram, M. A., Kraaij, R., Krumsiek, J., Newby, D., Nho, K., Radjabzadeh, D., Saykin, A. J., Shi, L., Sproviero, W., Winchester, L., Yang, Y. & Nevado-Holgado, A. J. & 3 others, Kastenmüller, G., Kaddurah-Daouk, R. & Van Duijn, C. M., 7 Jun 2023, In: JAMA Psychiatry. 80, 6, p. 597-609 13 p.
Research output: Contribution to journal › Article › peer-review
The impact of Short Tandem Repeats on grey matter brain imaging derived phenotypes in UK Biobank
Sproviero, W., Ghose, U., Winchester, L. M., Fernandes, M., Newby, D., Sproviero, D., Amin, N., Smets, B., He, K. Y., Khramtsova, E. A., Patel, P., Sarver, B. A. J., Howe, T., Black, M. H., van Duijn, C. & Nevado-Holgado, A., 1 Mar 2023, (Accepted/In press).
Research output: Working paper › Preprint
Open access
Comparative effect of metformin versus sulfonylureas with dementia and Parkinson's disease risk in US patients over 50 with type 2 diabetes mellitus
Newby, D., Linden, A. B., Fernandes, M., Molero, Y., Winchester, L., Sproviero, W., Ghose, U., Li, Q. S., Launer, L. J., Duijn, C. M. V. & Nevado-Holgado, A. J., 15 Sept 2022, In: BMJ Open Diabetes Research and Care. 10, 5, e003036.
Research output: Contribution to journal › Article › peer-review
Open access
Gene Ontology (GO)-driven inference of candidate proteomic markers associated with muscle atrophy conditions
Stalmach, A., Boehm, I., Fernandes, M., Rutter, A., Skipworth, R. J. E. & Husi, H., 27 Aug 2022, In: Molecules. 27, 17, 5514.
Research output: Contribution to journal › Article › peer-review
Open access
Glycosylated clusterin species facilitate Aβ toxicity in human neurons
Foster, E. M., Fernandes, M., Dangla-Valls, A., Hublitz, P., Pangalos, M., Lovestone, S., Ribe, E. M. & Buckley, N. J., 3 Nov 2022, In: Scientific Reports. 12, 18639.
Research output: Contribution to journal › Article › peer-review
Open access
Interplay of the human exposome, metabolome and gut microbiome in dementia and major depression
van Duijn, C. M., Amin, N., Liu, J., Bonnechere, B., MahmoudianDehkordi, S., Arnold, M., Batra, R., Chiou, Y. J., Fernandes, M., Ikram, M. A., Kraaij, R., Krumsiek, J., Newby, D., Nho, K., Radjabzadeh, D., Saykin, A. J., Shi, L., Sproviero, W., Winchester, L. M. & Yang, Y. & 3 others, Nevado-Holgado, A. J., Kastenmüller, G. & Kaddurah-Daouk, R., Dec 2022, In: Alzheimer's and Dementia. 18, S4, e067261.
Research output: Contribution to journal › Comment/debate › peer-review
Open access
Validation of UK Biobank data for mental health outcomes: a pilot study using secondary care electronic health records
Li, Z., Kormilitzin, A., Fernandes, M., Vaci, N., Liu, Q., Newby, D., Goodday, S., Smith, T., Nevado-Holgado, A. J. & Winchester, L., Apr 2022, In: International Journal of Medical Informatics. 160, 104704.
Research output: Contribution to journal › Article › peer-review

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