Prof David Harrison

Professor

Researcher profile

Phone

+44 (0)1334 46 4826

Email

djh20@st-andrews.ac.uk

PhD supervision

• Hazem Abdullah
• Anna Carberry
• Keira Hughes
• Myriam Kabu
• Minyeoung Kweon
• Clare Orange
• Ennio Pecaver
• Ngoc Anh Thu Trinh
• Rebecca Watts
• Greice Zickuhr

Selected publications

• Open access

  A good feature extractor is all you need for weakly supervised pathology slide classification

  Wölflein, G., Ferber, D., Meneghetti, A. R., El Nahhas, O. S. M., Truhn, D., Carrero, Z. I., Harrison, D. J., Arandjelović, O. & Kather, J. N., 30 May 2025, Computer vision – ECCV 2024 workshops, proceedings: Milan, Italy, September 29–October 4, 2024, proceedings, part XVI. Del Bue, A., Canton, C., Pont-Tuset, J. & Tommasi, T. (eds.). Cham: Springer, p. 68-87 20 p. (Lecture notes in computer science; vol. 15638 LNCS).

  Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

• Open access

  A phosphoramidate modification of FUDR, NUC-3373, causes DNA damage and DAMPs release from colorectal cancer cells, potentiating lymphocyte-induced cell death

  Read, O., Bre, J., Zhang, Y., Mullen, P., Elshani, M. & Harrison, D., 16 Sept 2025, In: PLoS One. 20, 9, p. 1-19 19 p., e0331567.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Determining the impact of histology on the incidence, pattern, and timing of recurrences in patients with renal cell carcinoma: a pooled analysis from the SORCE and ASSURE Trials

  Oza, B., Frangou, E., Eisen, T., Stewart, G. D., Bex, A., Harrison, D., Parmar, M. K. B., Langley, R., Gilbert, D. & Meade, A., Sept 2025, In: European Urology Open Science. 79, p. 19-26 8 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Improved nucleoside (2'-deoxy)ribosyltransferases maximize enzyme promiscuity while maintaining catalytic efficiency

  Tang, P., Zickuhr, G. M., Dickson, A. L., Harding, C. J., Devi, S., Lebl, T., Harrison, D. J., da Silva, R. G. & Melo Czekster, C., 17 Oct 2025, (E-pub ahead of print) In: ACS Chemical Biology. Article ASAP, 7 p.

  Research output: Contribution to journal › Letter › peer-review

• Open access

  Kidney tumoroid characterisation by spatial mass spectrometry with same-section multiplex immunofluorescence uncovers tumour microenvironment lipid signatures associated with aggressive tumour phenotypes

  Abdullah, H., Zickuhr, G. M., Um, I. H., Laird, A., Mullen, P., Harrison, D. J. & Dickson, A. L., 16 Sept 2025, In: npj Imaging. 3, p. 1-11 11 p., 43.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Kinetic and thermodynamic characterization of human 4-oxo-L-proline reductase catalysis

  Pecaver, E., Zickuhr, G. M., Machado, T. F. G., Harrison, D. J. & da Silva, R. G., 18 Feb 2025, In: Biochemistry. 64, 4, p. 860-870 11 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Leveraging knowledge for explainable AI in personalized cancer treatment: challenges and future directions

  Daghir-Wojtkowiak, E., Alfaro, J., Mastromattei, M., Palkowski, A., Stares, M., Roca-Umbert, A., Krajnc, A., Leoni, R., Boland, A., Nourbaksh, A., Kallor, A., Ducki, C., Venditti, D., Montesano, C., Cipriani, C., Faria, D., Pflieger, D., Zago, E., Bardet, E. & Serrano, F. & 75 others, Jeanneret, F., Alouges, D., Yin, L., Coquelet, E., Bacquet, A., Bonchi, F., Maiorino, F., Torino, F., Bedran, G., Long, J.-A., Balbi, L., Guyon, L., Bevilacqua, L., Fiorelli, M., Wagner, M.-C., Reyes, M., Roselli, M., Silva, M. C., Waleron, M., Dovrolis, N., Filhol-Cochet, O., Um, I. H., Wolflein, G., Eugénio, P., Bazelle, P., Golnas, P., Thorpe, P., Bove, P., Borole, P., Bernardini, R., Kumar, R., Cicconi, R., Kaltenbrunner, S., Gravina, S., Brezar, S., Symeonides, S., McGinn, S., Nunes, S., Hupp, T., Gordienko, Y., Varvaras, D., Stirenko, S., Xumerle, L., Mariani, S., Bouzit, A., Gazut, S., Poth, H., Souliotis, K., Katifelis, H., Verzoni, E., Procopio, G., Schoch, S., Lupiáñez-Villanueva, F., Türk, S., Barud, K., Koroliouk, D., Caubet, J., Moreno, Y., Descotes, J.-L., Golna, C., Guadalupi, V., Garagnani, P., Gazouli, M., Deleuze, J.-F., Folkvord, F., Forgó, N., Harrison, D. J., Axelson, H., Stellato, A., Mattei, M., Rajan, A., Laird, A., Battail, C., Pesquita, C. & Zanzotto, F. M., 29 Sept 2025, In: Frontiers in Digital Health. 7, p. 1-10 10 p., 104267.

  Research output: Contribution to journal › Article › peer-review

• Open access

  SurGen: 1020 H&E-stained whole slide images with survival and genetic markers

  Myles, C., Um, I., Marshall, C., Harris-Birtill, D. & Harrison, D., 2025, In: GigaScience. 14, p. 1-16 16 p., giaf086.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Adapting the design of the ongoing RAMPART trial in response to external evidence: an example for trials which take many years to run and report

  Meade, A., Frangou, E., Choodari-Oskooei, B., Larkin, J., Powles, T., Stewart, G. D., Albiges, L., Bex, A., Choueiri, T. K., Davis, I. D., Eisen, T., Fielding, A., Gedye, C., Harrison, D. J., Kaplan, R., Mulhere, S., Nathan, P., Patel, G., Patel, J. & Plant, H. & 9 others, Ritchie, A., Rush, H., Shakeshaft, C., Stockler, M. R., Suarez, C., Thompson, J., Thorogood, N., Venugopal, B. & Parmar, M. K. B., 1 Dec 2024, In: Contemporary Clinical Trials Communications. 42, 5 p., 101381.

  Research output: Contribution to journal › Article › peer-review

• Open access

  A phase I open-label, dose-escalation study of NUC-3373, a targeted thymidylate synthase inhibitor, in patients with advanced cancer (NuTide:301)

  Spiliopoulou, P., Kazmi, F., Aroldi, F., Holmes, T., Thompson, D., Griffiths, L., Qi, C., Parkes, M., Lord, S., Veal, G. J., Harrison, D. J., Coyle, V. M., Graham, J., Jeffry Evans, T. R. & Blagden, S. P., 2 Apr 2024, In: Journal of Experimental & Clinical Cancer Research. 43, 16 p.

  Research output: Contribution to journal › Article › peer-review

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