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Prof Andy Lynch

Prof Andy Lynch

Professor of Statistics in Bioscience

Researcher profile

Email
andy.lynch@st-andrews.ac.uk

 

PhD supervision

  • Victor Velasco Pardo
  • Xiaoyue Yang
  • Naici Guo
  • Filippo Abbondanza

Selected publications

  • Deciphering the genomic, epigenomic and transcriptomic landscapes of pre-invasive lung cancer lesions

    Texeira, V. H., Pipinikas, C. P., Pennycuick, A., Lee-Six, H., Chandrasekharan, D., Beane, J., Morris, T. J., Karpathakis, A., Feber, A., Breeze, C. E., Ntolios, P., Hynds, R. E., Falzon, M., Capitanio, A., Carroll, B., Durrenberger, P. F., Hardavella, G., Brown, J. M., Lynch, A. G., Farmery, H., Paul, D. S., Chambers, R. C., McGranahan, N., Navani, N., Thakrar, R. M., Swanton, C., Beck, S., George, P. J., Spira, A., Campbell, P. J., Thirwell, C. & Janes, S. M., Mar 2019, In : Nature Medicine. 25, p. 517-525 9 p.

    Research output: Contribution to journal ? Article

  • Different laterality indexes are poorly correlated with one another but consistently show the tendency of males and females to be more left- and right- lateralised, respectively

    Buenaventura Castillo, C., Lynch, A. & Paracchini, S., 26 Sep 2019, In : PsyArXiv. 16 p.

    Research output: Contribution to journal ? Article

  • Multicenter validation of the CamGFR model for estimated glomerular filtration rate

    Williams, E. H., Connell, C. M., Weaver, J. M. J., Beh, I., Potts, H., Whitley, C. T., Bird, N., Al-Sayed, T., Fehr, M., Cathomas, R., Bertelli, G., Quinton, A., Lewis, P., Shamash, J., Wilson, P., Dooley, M., Poole, S., Mark, P. B., Bookman, M., Earl, H., Jodrell, D., Tavaré, S., Lynch, A. & Janowitz, T., Dec 2019, In : JNCI Cancer Spectrum. 3, 4, 4 p., pkz068.

    Research output: Contribution to journal ? Article

  • DESNT: a poor prognosis category of human prostate cancer

    Luca, B-A., Brewer, D. S., Edwards, D. R., Edwards, S., Whitaker, H. C., Merson, S., Dennis, N., Cooper, R. A., Hazell, S., Warren, A. Y., Eeles, R., Lynch, A. G., Ross-Adams, H., Lamb, A. D., Neal, D. E., Sethia, K., Mills, R. D., Ball, R. Y., Curley, H., Clark, J., Moulton, V. & Cooper, C. S., Dec 2018, In : European Urology Focus. 4, 6, p. 842-850 9 p.

    Research output: Contribution to journal ? Article

  • Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets

    Wedge, D. C., Gundem, G., Mitchell, T., Woodstock, D. J., Martincorena, I., Ghori, M., Zamora, J., Butler, A., Whitaker, H., Kote-Jarai, Z., Alexandrov, L. B., Van Loo, P., Massie, C. E., Dentro, S., Warren, A. Y., Verrill, C., Berney, D. M., Dennis, N., Merson, S., Hawkins, S., Howat, W., Lu, Y-J., Lambert, A., Kay, J., Kremeyer, B., Karaszi, K., Camacho, N., Luxton, H., Marsden, L., Edwards, S., Matthews, L., Bo, V., Leongamornlert, D., McLaren, S., Ng, A., Yu, Y., Zhang, H., Dadaev, T., Thomas, S., Easton, D. F., Ahmed, M., Bancroft, E., Fisher, C., Livni, N., Nicol, D., Tavaré, S., Gill, P., Greenman, C., Khoo, V., Van As, N., Kumar, P., Ogden, C., Cahill, D., Thompson, A., Mayer, E., Rowe, E., Dudderidge, T., Gnanapragasam, V., Shah, N. C., Raine, K., Jones, D., Menzies, A., Stebbings, L., Teague, J., Hazell, S., Corbishley, C., CamCaP Study Group, de Bono, J., Attard, G., Isaacs, W., Visakorpi, T., Fraser, M., Boutros, P. C., Bristow, R. G., Workman, P., Sander, C., The TCGA Consortium, Hamdy, F. C., Futreal, A., McDermott, U., Al-Lazikani, B., Lynch, A., Bova, G. S., Foster, C. S., Brewer, D. S., Neal, D. E., Cooper, C. S. & Eeles, R. A., 16 Apr 2018, In : Nature Genetics. 50, p. 682-692 16 p.

    Research output: Contribution to journal ? Article

  • Telomerecat: a ploidy-agnostic method for estimating telomere length from whole genome sequencing data

    Farmery, J., Smith, M., NIHR BioResource - Rare Diseases & Lynch, A., 22 Jan 2018, In : Scientific Reports. 8, 17 p., 1300.

    Research output: Contribution to journal ? Article

  • The role of TET-mediated DNA hydroxymethylation in prostate cancer

    Smeets, E., Lynch, A. G., Prekovic, S., Van den Broeck, T., Moris, L., Helsen, C., Joniau, S., Claessens, F. & Massie, C. E., 15 Feb 2018, In : Molecular and Cellular Endocrinology. 462, A, p. 41-55

    Research output: Contribution to journal ? Review article

  • Timing the landmark events in the evolution of clear cell renal cell cancer: TRACERx renal

    Mitchell, T. J., Turajlic, S., Rowan, A., Nicol, D., Farmery, J. H. R., O?Brien, T., Martincorena, I., Tarpey, P., Angelopoulos, N., Yates, L. R., Butler, A. P., Raine, K., Stewart, G. D., Challacombe, B., Fernando, A., Lopez, J. I., Hazell, S., Chandra, A., Chowdhury, S., Rudman, S., Soultati, A., Stamp, G., Fotiadis, N., Pickering, L., Au, L., Spain, L., Lynch, J., Stares, M., Teague, J., Maura, F., Wedge, D. C., Horswell, S., Chambers, T., Litchfield, K., Xu, H., Stewart, A., Elaidi, R., Oudard, S., McGranahan, N., Csabai, I., Gore, M., Futreal, P. A., Larkin, J., Lynch, A. G., Szallasi, Z., Swanton, C. & Campbell, P. J., 19 Apr 2018, In : Cell. 173, 3, p. 611-623 13 p., e17.

    Research output: Contribution to journal ? Article

  • A comparative analysis of whole genome sequencing of esophageal adenocarcinoma pre- and post-chemotherapy

    Noorani, A., Bornschein, J., Lynch, A. G., Secrier, M., Achilleos, A., Eldridge, M., Bower, L., Weaver, J. M. J., Crawte, J., Ong, C-A., Shannon, N., MacRae, S., Grehan, N., Nutzinger, B., O'Donovan, M., Hardwick, R., Tavaré, S., Fitzgerald, R. C. & Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium, 1 Jun 2017, In : Genome Research. 27, 6, p. 902-912 11 p.

    Research output: Contribution to journal ? Article

  • Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data

    Camacho, N., Van Loo, P., Edwards, S., Kay, J. D., Matthews, L., Haase, K., Clark, J., Dennis, N., Thomas, S., Kremeyer, B., Zamora, J., Butler, A. P., Gundem, G., Merson, S., Luxton, H., Hawkins, S., Ghori, M., Marsden, L., Lambert, A., Karaszi, K., Pelvender, G., Massie, C. E., Kote-Jarai, ZS., Raine, K., Jones, D., Howat, W. J., Hazell, S., Livni, N., Fisher, C., Ogden, C., Kumar, P., Thompson, A., Nicol, D., Mayer, E., Dudderidge, T., Yu, Y., Zhang, H., Shah, N. C., Gnanapragasam, V. J., Group, T. CRUK-ICGC. P., Isaacs, W., Visakorpi, T., Hamdy, F., Berney, D., Verrill, C., Warren, A. Y., Wedge, D. C., Lynch, A. G., Foster, C. S., Lu, Y. J., Bova, G. S., Whitaker, H. C., McDermott, U., Neal, D. E., Eeles, R., Cooper, C. S. & Brewer, D. S., 25 Sep 2017, In : PLoS Genetics. 13, 9, e1007001.

    Research output: Contribution to journal ? Article

 

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