Dr Helen Connaris

Senior Research Fellow in Enzyme Production, Purification and Assessment (Translationally Focused)

Researcher profile

Phone

+44 (0)1334 46 7257

Email

hc6@st-andrews.ac.uk

 

Selected publications

• Open access

  Halogenases: a palette of emerging opportunities for synthetic biology–synthetic chemistry and C–H functionalisation

  Crowe, C., Molyneux, S., Sharma, S. V., Zhang, Y., Gkotsi, D. S., Connaris, H. & Goss, R. J. M., 7 Sep 2021, In: Chemical Society Reviews. 17, 50, p. 9443-9481 39 p.

  Research output: Contribution to journal › Review article › peer-review

• Immunomodulatory Compounds

  Taylor, G. L. & Connaris, H., 30 Jul 2015, IPC No. A61K31/74, Patent No. WO2015110831 (A1)

  Research output: Patent

• Open access

  Sialic acid-binding protein Sp2CBMTD protects mice against lethal challenge with emerging influenza A (H7N9) virus

  Govorkova, E. A., Baranovich, T., Marathe, B. M., Yang, L., Taylor, M. A., Webster, R. G., Taylor, G. L. & Connaris, H., Mar 2015, In: Antimicrobial Agents and Chemotherapy. 59, 3, p. 1495-1504 10 p.

  Research output: Contribution to journal › Article › peer-review

• Open access

  Structural characterization of the carbohydrate-binding module of NanA sialidase, a pneumococcal virulence factor

  Yang, L., Connaris, H., Potter, J. A. & Taylor, G. L., 20 Aug 2015, In: BMC Structural Biology. 15, 10 p., 15.

  Research output: Contribution to journal › Article › peer-review

• Prevention of influenza by targeting host receptors using engineered proteins

  Connaris, H., Govorkova, E. A., Ligertwood, Y., Dutia, B. M., Yang, L., Tauber, S., Taylor, M. A., Alias, N., Hagan, R., Nash, A. A., Webster, R. G. & Taylor, G. L., 29 Apr 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 17, p. 6401-6406

  Research output: Contribution to journal › Article › peer-review

• Carbohydrate Binding Molecules

  Connaris, H. & Taylor, G. L., 3 Nov 2011, IPC No. A61P31/04, Patent No. US2011269670 (A1)

  Research output: Patent

• Enhancing the receptor affinity of the sialic acid-binding domain of Vibrio cholerae sialidase through multivalency

  Connaris, H., Crocker, PR. & Taylor, G. L., 13 Mar 2009, In: Journal of Biological Chemistry. 284, p. 7339-7351 13 p.

  Research output: Contribution to journal › Article › peer-review

• Sialic acid recognition by Vibrio cholerae neuraminidase

  Moustafa, I., Connaris, H., Taylor, M., Zaitsev, V., Wilson, JC., Kiefel, MJ., von Itzstein, M. & Taylor, G. L., 24 Sep 2004, In: Journal of Biological Chemistry. 279, 39, p. 40819-40826 8 p.

  Research output: Contribution to journal › Article › peer-review

• The Structural Basis for Substrate Promiscuity in 2-Keto-3-deoxygluconate aldolase from the Entner-Doudoroff Pathway in Sulfolobus solfataricus

  Theodossis, A., Walden, H., Westwick, EJ., Connaris, H., Lamble, HJ., Hough, DW., Danson, MJ. & Taylor, G. L., 15 Oct 2004, In: Journal of Biological Chemistry. 279, 42, p. 43886-43892 7 p.

  Research output: Contribution to journal › Article › peer-review

• Probing the sialic acid binding site of the hemagglutinin-neuraminidase of Newcastle disease virus: identification of key amino acids involved in cell binding, catalysis and fusion

  Connaris, H., Takimoto, T., Russell, R. J. M., Crennell, S., Moustafa, I., Portner, A. & Taylor, G. L., Feb 2002, In: Journal of Virology. 76, 4, p. 1816-1824 9 p.

  Research output: Contribution to journal › Article › peer-review

 

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