Prof Douglas Philp
Professor
Research areas
Our laboratory is engaged in developing synthetic routes to complex, functional systems through the programmed application of non-covalent interactions in self-assembly and in replication processes. At all levels, our research exploits the interplay between experimental and computational science, encompassing synthetic chemistry, reaction kinetics, numerical simulations, advanced spectroscopic methods and computational chemistry for the design and construction of complex chemical systems. Our approach involves the reshaping of principles from life sciences by creating a wholly synthetic chemical framework that exploits the principles of dynamic systemic resolution, out-of-equilibrium processes and replication to create chemical systems that display complex behaviour.
PhD supervision
- Virginie Viseur
- Laura Gravener
- Lucy Hutton
Selected publications
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Open access
Two synthetic replicators compete to process a dynamic reagent pool
Kosikova, T. & Philp, D., 20 Feb 2019, In: Journal of the American Chemical Society. 141, 7, p. 3059-3072 14 p.Research output: Contribution to journal › Article › peer-review
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Open access
An environmentally responsive reciprocal replicating network
Robertson, C. C., Mackenzie, H. W., Kosikova, T. & Philp, D., 6 Jun 2018, In: Journal of the American Chemical Society. 140, 22, p. 6832-6841 10 p.Research output: Contribution to journal › Article › peer-review
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Open access
Exploring the emergence of complexity using synthetic replicators
Kosikova, T. & Philp, D., 7 Dec 2017, In: Chemical Society Reviews. 46, 23, p. 7274-7305Research output: Contribution to journal › Article › peer-review
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Open access
Generating system-level responses from a network of simple synthetic replicators
Sadownik, J. W., Kosikova, T. & Philp, D., 6 Dec 2017, In: Journal of the American Chemical Society. 139, 48, p. 17565-17573Research output: Contribution to journal › Article › peer-review
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Open access
A critical cross-catalytic relationship determines the outcome of competition in a replicator network
Kosikova, T. & Philp, D., 13 Sept 2017, In: Journal of the American Chemical Society. 139, 36, p. 12579-12590 12 p.Research output: Contribution to journal › Article › peer-review
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Open access
A synthetic replicator drives a propagating reaction-diffusion front
Bottero, I., Huck, J., Kosikova, T. & Philp, D., 1 Jun 2016, In: Journal of the American Chemical Society. 138, 21, p. 6723-6726 4 p.Research output: Contribution to journal › Article › peer-review
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Open access
Orthogonal recognition processes drive the assembly and replication of a [2]rotaxane
Kosikova, T., Hassan, N. I. B., Cordes, D. B., Slawin, A. M. Z. & Philp, D., 30 Dec 2015, In: Journal of the American Chemical Society. 137, 51, p. 16074–16083Research output: Contribution to journal › Article › peer-review