Prof Terry K Smith
Director of Biomedical Sciences Research Complex
Professor
Research areas
1) Biosynthesis and uptake of phospholipids in protozoan parasites.
2) The enzymology of biosynthetic enzymes in parasites.
3) Lipidomics and focussed metabolomics of pathogens.
4) Carbohydrate synthesis and “simple” chemistry towards drugs for neglected disease.
5) Structure, function & biosynthesis of parasite glycoconjugates including GPI anchors.
PhD supervision
- Rachel Humann
- Veronica Harris
- Nora Von Xylander
- Peter Black
- Ngoc Anh Thu Trinh
- Vytautas Kuodis
- Berta Fatas
Selected publications
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Open access
The role of ion dissolution in metal and metal oxide surface inactivation of SARS CoV-2
Hilton, J. V., Nanao, Y., Flokstra, M. G., Askari, M., Smith, T. K., Di Falco, A., King, P., Wahl, P. & Adamson, C. S., Feb 2024, In: Applied and Environmental Microbiology. 90, 2, 15 p., e01553-23.Research output: Contribution to journal › Article › peer-review
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Open access
A type VII-secreted lipase toxin with reverse domain arrangement
Garrett, S. R., Mietrach, N., Deme, J., Bitzer, A., Yang, Y., Ulhuq, F. R., Kretschmer, D., Heilbronner, S., Smith, T. K., Lea, S. M. & Palmer, T., 19 Dec 2023, In: Nature Communications. 14, 16 p., 8438.Research output: Contribution to journal › Article › peer-review
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Open access
Adipocyte lipolysis protects mice against Trypanosoma brucei infection
Machado, H., Hofer, P., Zechner, R., Smith, T. K. & Figueiredo, L. M., 12 Oct 2023, In: Nature Microbiology. 8, p. 2020-2032 27 p.Research output: Contribution to journal › Article › peer-review
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Open access
An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host
Price, J. A., Ali, M. F., Major, L. L., Smith, T. K. & Jones, J. T., 13 Feb 2023, In: PLoS Pathogens. 19, 2, 19 p., e1011147.Research output: Contribution to journal › Article › peer-review
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Open access
Disruption of the inositol phosphorylceramide synthase gene affects Trypanosoma cruzi differentiation and infection capacity
Dos Santos, N. S. A., Estevez-Castro, C. F., Macedo, J. P., Chame, D. F., Castro-Gomes, T., Santos-Cardoso, M., Burle-Caldas, G. A., Covington, C. N., Steel, P. G., Smith, T. K., Denny, P. W. & Teixeira, S. M. R., 20 Sept 2023, In: PLoS Neglected Tropical Diseases. 17, 9, 26 p., e0011646.Research output: Contribution to journal › Article › peer-review
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Open access
New insights in photodynamic inactivation of Leishmania amazonensis: a focus on lipidomics and resistance
Cabral, F. V., Cerone, M., Persheyev, S., Lian, C., Samuel, I. D. W., Ribeiro, M. S. & Smith, T. K., 15 Sept 2023, In: PLoS ONE. 18, 9, e0289492.Research output: Contribution to journal › Article › peer-review
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Open access
Organic and inorganic light-emitting diodes for photodynamic therapy of cutaneous Leishmaniasis
Persheyev, S., Samuel, I. D. W. & Smith, T. K., 29 Aug 2023, In: Global Journal of Infectious Diseases and Clinical Research. 9, 1, p. 025-030Research output: Contribution to journal › Article › peer-review
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Open access
Sterols, free fatty acids, and total fatty acid content in the massive Porites spp. corals cultured under different pCO2 and temperature treatments
von Xylander, N. S. H., Young, S., Cole, C. S., Smith, T. K. & Allison, N., 1 Apr 2023, In: Coral Reefs. 42, p. 551-566 16 p.Research output: Contribution to journal › Article › peer-review
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Open access
Surface-Functionalized Metal-Organic Frameworks for Binding Coronavirus Proteins
Desai, A. V., Vornholt, S. M., Major, L. L., Ettlinger, R., Jansen, C., Rainer, D., de Rome, R., So, V., Wheatley, P. S., Edward, A. K., Elliott, C., Pramanik, A., Karmakar, A., Armstrong, R., Janiak, C., Smith, T. K. & Morris, R. E., 22 Feb 2023, In: ACS Applied Materials & Interfaces. 15, 7, p. 9058–9065 8 p.Research output: Contribution to journal › Article › peer-review
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Surface-Functionalized Metal-Organic Frameworks for Binding Coronavirus Proteins
Desai, AV., Vornholt, SM., Major, LL., Ettlinger, R., Jansen, C., Rainer, DN., de Rome, R., So, V., Wheatley, PS., Edward, AK., Elliott, CG., Pramanik, A., Karmakar, A., Armstrong, R., Janiak, C., Smith, TK. & Morris, RE., 14 Feb 2023, (E-pub ahead of print) In: ACS Applied Materials & Interfaces. 8 p.Research output: Contribution to journal › Article › peer-review