Dr Louise Major
Technical Manager (Research)
Selected publications
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Open access
Building a cell-factory in Crithidia fasciculata: a bio-sustainable system to produce high-value polyunsaturated fatty acids
Cerone, M., Major, L. L. & Smith, T. K., 23 Jun 2025, In: Microbial Cell Factories. 24, p. 1-16 16 p., 142.Research output: Contribution to journal › Article › peer-review
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Open access
High-throughput screening of potent drug-like molecules targeting 17β-HSD10 for the treatment of Alzheimer's disease and cancer
Aitken, L., Baillie, G., Pannifer, A., Morrison, A., Major, L. L., Alphey, M. S., Sethi, R., Timmerman, M., Robinson, J., Riley, J., Shishikura, Y., Koekemoer, L., Von Delft, F., Rutjes, H., Read, K., Jones, P. S., McElroy, S. P., Smith, T. K. & Gunn-Moore, F. J., 18 Jun 2025, (E-pub ahead of print) In: ACS Chemical Biology. ASAP, p. 1-16 16 p.Research output: Contribution to journal › Article › peer-review
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Open access
Inactivating SARS-CoV-2 virus with MOF-composites as smart face masks
Ettlinger, R., Desai, A. V., Cheong, H. L. J., Major, L. L., Smith, T. K., Naden, A. B., Hilton, J., Adamson, C. S., Armstrong, A. R. & Morris, R. E., 2 Oct 2025, (E-pub ahead of print) In: Advanced Functional Materials. Early View, p. 1-7 7 p.Research output: Contribution to journal › Article › peer-review
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Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents
Garsi, J. B., Hocine, S., Hensienne, R., Moitessier, M., Denton, H., Major, L. L., Smith, T. K. & Hanessian, S., 15 Sept 2024, In: Bioorganic and Medicinal Chemistry Letters. 110, 12 p., 129883.Research output: Contribution to journal › Article › peer-review
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Open access
An eggshell-localised annexin plays a key role in the coordination of the life cycle of a plant-parasitic nematode with its host
Price, J. A., Ali, M. F., Major, L. L., Smith, T. K. & Jones, J. T., 13 Feb 2023, In: PLoS Pathogens. 19, 2, 19 p., e1011147.Research output: Contribution to journal › Article › peer-review
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Open access
Surface-Functionalized Metal-Organic Frameworks for Binding Coronavirus Proteins
Desai, A. V., Vornholt, S. M., Major, L. L., Ettlinger, R., Jansen, C., Rainer, D., de Rome, R., So, V., Wheatley, P. S., Edward, A. K., Elliott, C., Pramanik, A., Karmakar, A., Armstrong, R., Janiak, C., Smith, T. K. & Morris, R. E., 22 Feb 2023, In: ACS Applied Materials & Interfaces. 15, 7, p. 9058–9065 8 p.Research output: Contribution to journal › Article › peer-review
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Open access
Towards chemical validation of Leishmania infantum ribose 5-phosphate isomerase as a drug target
Dickie, E. A., Ronin, C., Sá, M., Ciesielski, F., Trouche, N., Tavares, J., Santarem, N., Major, L. L., Pemberton, I. K., MacDougall, J., Smith, T. K., Cordeiro-da-Silva, A. & Ciapetti, P., 19 Apr 2021, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy. EarlyResearch output: Contribution to journal › Article › peer-review
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Open access
Synthesis, study of antileishmanial and antitrypanosomal activity of imidazo pyridine fused triazole analogues
Nandikolla, A., Srinivasarao, S., Karan Kumar, B., Murugesan, S., Aggarwal, H., Major, L. L., Smith, T. K. & Chandra Sekhar, K. V. G., 19 Oct 2020, In: RSC Advances. 10, 63, p. 38328-38343 16 p.Research output: Contribution to journal › Article › peer-review
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Open access
Novel benzothiazole-based ureas as 17β-HSD10 inhibitors, a potential Alzheimer’s disease treatment
Aitken, L., Benek, O., McKelvie, B., Hughes, R. E., Hroch, L., Schmidt, M., Major, L. L., Vinklarova, L., Kuca, K., Smith, T. K., Musilek, K. & Gunn-Moore, F. J., 29 Jul 2019, In: Molecules. 24, 15, 2757.Research output: Contribution to journal › Article › peer-review
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Open access
Inhibitors of Trypanosoma cruzi Sir2 related protein 1 as potential drugs against Chagas disease
Gaspar, L., Coron, R. P., Kongthoo Lin, P., Costa, D. M., Perez-Cabezas, B., Tavares, J., Roura-Ferrer, M., Ramos, I., Ronin, C., Major, L. L., Ciesielski, F., Pemberton, I. K., MacDougall, J., Ciapetti, P., Smith, T. K. & Cordeiro-da-Silva, A., 22 Jan 2018, In: PLoS Neglected Tropical Diseases. 12, 1, 30 p., e0006180.Research output: Contribution to journal › Article › peer-review