Dr Christopher Harding
Research Fellow
Selected publications
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Open access
Snapshots of the reaction coordinate of a thermophilic 2'-deoxyribonucleoside/ribonucleoside transferase
Tang, P., Harding, C. J., Dickson, A., da Silva, R. G., Harrison, D. J. & Melo Czekster, C., 1 Mar 2024, In: ACS Catalysis. 14, 5, p. 3090-3102 13 p.Research output: Contribution to journal › Article › peer-review
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Open access
An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa
Harding, C. J., Bischoff, M., Bergkessel, M. & Melo Czekster, C., 1 Sept 2023, In: Nature Chemical Biology. 19, 9, p. 1158-1166 15 p.Research output: Contribution to journal › Article › peer-review
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Open access
Unveiling the catalytic mechanism of a processive metalloaminopeptidase
Simpson, M. C., Harding, C. J., Czekster, R., Remmel, L., Bode, B. E. & Melo Czekster, C., 4 Nov 2023, (E-pub ahead of print) In: Biochemistry. Articles ASAP, 18 p.Research output: Contribution to journal › Article › peer-review
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Open access
Active site remodelling of a cyclodipeptide synthase redefines substrate scope
Sutherland, E., Harding, C. J. & Melo Czekster, C., 25 Aug 2022, In: Communications Chemistry. 5, 1, 10 p., 101.Research output: Contribution to journal › Article › peer-review
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Open access
A rotary mechanism for allostery in bacterial hybrid malic enzymes
Harding, C. J., Cadby, I. T., Moynihan, P. J. & Lovering, A. L., 23 Feb 2021, In: Nature Communications. 12, 12 p., 1228.Research output: Contribution to journal › Article › peer-review
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Open access
Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme
Harding, C. J., Sutherland, E., Hanna, J., Houston, D. & Melo Czekster, C., 15 Jan 2021, (E-pub ahead of print) In: RSC Chemical Biology. Advance article, 11 p.Research output: Contribution to journal › Article › peer-review
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Open access
Erratum: Bypassing the requirement for aminoacyl-tRNA by a cyclodipeptide synthase enzyme (RSC Chem. Biol. (2021) 2 (230-240) DOI: 10.1039/D0CB00142B)
Harding, C. J., Sutherland, E., Hanna, J. G., Houston, D. R. & Czekster, C. M., Jun 2021, In: RSC Chemical Biology. 2, 3, p. 942-943 2 p.Research output: Contribution to journal › Comment/debate › peer-review