Single-molecule Biophysics and Fluorescence Spectroscopy Lab

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Publications

Structural insights into the ligand-controlled organization of SAM-sensing riboswitches. Heppel, B., Blouin S., Mulhbacher, J., Ennifar, J., Penedo*, J. C. and Lafontaine*, D. A. Submitted. Nat. Struct. Mol. Biol. 2010

PCNA and XPF cooperate to distort DNA substrates. Hutton, R. D., Craggs, T. D., White*, M. F. and J. Carlos Penedo*. Nucleic Acid. Res.  38(5), 1664-1675, 2010

Riboswitches: Ancient and promising genetic regulators. Blouin S., Mulhbacher J, Penedo JC, Lafontaine DA. ChemBioChem., 10(3), 400-416, 2009

Application of fluorescent measurements for characterization of riboswitch-ligand interactions. Heppell B, Mulhbacher J, Penedo JC, Lafontaine DA. Methods in Molecular Biology, Vol 540, Riboswitches, A. Serganov, eds.; Humana Press: New Jersey, 2009. ISBN: 978-1-934115-88-6

Functional studies of DNA-protein interactions using FRET techniques. Blouin, Lafontaine, DA, Penedo* JC. Methods in Molecular Biology, Vol 543, T. Moss and B. Leblanc, eds.; Humana Press: New Jersey, 2009. ISBN: 978-1-60327-014-4

Molecular basis of RNA-mediated gene regulation on the adenine riboswitch by single-molecule approaches. Lemay JF, Mulhbacher J, Penedo JC, Lafontaine DA. Methods in Molecular Biology, Vol 540, Riboswitches, A. Serganov, eds.; Humana Press: New Jersey, 2009. ISBN: 978-1-934115-88-6

Natural Functional Nucleic Acids: Ribozymes and Riboswitches, Tremblay, R., Mulbacher, J., Penedo, J. C., Lafontaine, D. A., Chapter Book, “Functional Nucleic Acids for Sensing and Other Analytical Applications”.  Editors: Lu, Y., Li, Y., Kluwer-Springer Academic Publishers, 2008. ISBN: 978-0-387-73710-2

PCNA stimulates catalysis by structure specific nucleases using two distinct mechanisms: substrate targeting and catalytic step. Richard Hutton; Jennifer A. Roberts; J. Carlos Penedo*; Malcolm F. White*., Nucleic. Acid. Res. 36(21), 6720-6727, 2008

Solvent dependent photophysics of fac-[Rec(CO)3(11,12-X2dppz)(py)]+ (X=H, Me, F). Dyer, J., Creely, C. M., Penedo, J. C., Grills, D. C., Hudson, S., Matousek, P., Parker, A. W., Towrie, M., Kelly, J. M., George, M. W., Photochemical and Photobiological Sciences, 2007, 6(7), 741-8

Folding of the adenine riboswitch., Lemay J. –F, Penedo, J. C., Tremblay R., Lilley DMJ., Lafontaine, D. A., Chemistry and Biology, 2006, 13(8) 857.  (Cover of the volume). Preview in the same volume: 13(8), 807, 2006, and highlighted in Faculty of 1000 Biology

 Two Competitive Routes in the Lactim/Lactam Phototautomerization of a Hydroxypyridine Derivative Cation in Water: Dissociative Mechanism versus Water-Assisted Proton Transfer. Penedo, J. C.,Pérez-Lustres J. L.; Ríos-Rodriguez, M.C.; Rodriguez-Prieto, F.; Mosquera, M.; Accepted for publication in  J. Phys. Chem. A., 2005, 109, 10189

Photophysical study of a family of [Ru(phen)2(Mendpq)]2+ complexes in several solvents and DNA: a specific water effect promoted by methyl substitution., Karen O´Donoghue, J. Carlos Penedo, John M. Kelly, Paul E. Kruger.Dalton Transactions, 2005, 6, 1123

Solvent-Dependent Ground- and Excited-State Tautomerism in 2-(6´-Hydroxy-2’-pyridil)benzimidazole. Penedo, J. C.; Perez-Lustres, J.L.; García-Lema, I; Ríos-Rodriguez, M. C.; Mosquera, M.; Rodriguez-Prieto, F.;  J. Phys. Chem. A., 2004, 108, 6117

Folding of the natural hammerhead ribozyme is enhanced by interaction of auxiliary elements. J. C. Penedo, T. J. Wilson, S. D. Jayasena, A. Khvorova, D. M. J. Lilley.  RNA 10 (5), 2004, 880.

 Ultrafast Transient Absorption Studies of Ruthenium and Rhenium Dipyridophenazine Complexes Bound to DNA and Polynucleotides. Creely, Caitriona M.; Kelly, John M.; Feeney, M. M.; Hudson, S.; Penedo, J. C.; Blau, Werner J.; Elias, B.; Kirsch-De Mesmaeker, Andree; Matousek, P.;Towrie, M.; Parker, A. W.; Dyer, J. S.; George, Mikhael W.; Coates, C. G.;McGarvey, John J. Proc. SPIE , 2002, 4876, p. 92-103.

Role of Hydrogen-Bonded Adducts in Excited-State Proton-Transfer Processes. Penedo, JC; Mosquera, M.; Rodriguez-Prieto, F. J. Phys. Chem. A, 2000, 104, 7429-7441

On the Mechanism of Alcohol-Catalyzed Excited-State Intramolecular Proton Transfer in Cationic Benzimidazoles. Rios-Rodriguez, M. C.; Penedo, J. C.; Willemse, R. J.; Mosquera, M.; Rodriguez-Prieto. J. Phys. Chem., 1999, 103, 7236-7243

Solvent Control of Molecular Structure and Excited-State Proton-Transfer Processes of 1-methyl-2-(2'-hydroxyphenyl)benzimidazole. Rodriguez-Prieto, F.; Penedo, J.C.; Mosquera, M.; J. Chem. Soc., Faraday Trans., 1998, 94, 2775-2782.

Photoinduced Inter- and Intramolecular Proton Transfer in Aqueous and Ethanolic Solutions of 2-(2'-hydroxyphenyl) benzimidazole: Evidence for Tautomeric and Conformational Equilibria in the Ground State. Mosquera, M.; Penedo, J.C.; Rios-Rodriguez, M. C.; Rodriguez-Prieto, F., J. Phys. Chem., 1996, 100, 5398

 

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