Principal Investigator: Prof. Carlos Penedo

We are currently focused in the following main areas:

1. New dyes with improved photophysics, brighter, more photostable

2. Fighting pathogens: metabolite-sensing RNA-mediared gene-regulation processes

3. New fluorescent labeling strategies and ortoghonal chemistries for single-molecule FRET studies

4. Molecular machines involved in DNA and RNA processing

5. Single-molecule studies of conjugated light-emitting polymers

6. Single-molecule characterization of ubiquitin and sumo-related pathways

7. Mechanosensitive proteins

The two schemes below show the main biology areas in which we are currently working and the main single-molecule biophysical tools available in our labs in the School of Physics and the Shool of Biology: