Day by Day Program

Day by Day Program
August 11 (Monday)
8:45 - 12:20 Opening Ceremony & Plenary Lectures (Main Ballroom, Lory Student Center, 2nd Floor)

8:45		OPENING CEREMONY

9:00		Chair: Professor Steven M. Weinreb (Pennsylvania State University)
		*11-PL-1*
		Professor David MacMillan California Institute of Technology, USA
		Enantioselective Organocatalysis: Development of New Catalysis Concepts of Broad Utility to Chemical Synthesis

10:00		Chair: Professor Tomislav Rovis (Colorado State University, USA)
		*11-PL-2*
		Professor Ben Feringa University of Groningen, The Netherlands
		New Approaches in Asymmetric Catalysis

11:00 - 11:20			BREAK

11:20		Chair: Professor Yian Shi (Colorado State University)
		*11-PL-3*
		Professor Miwako Mori Hokkaido University, Japan
		Novel Synthesis of Heterocycles Using Transition Metal- Mediated or -Catalyzed Reactions

12:20			LUNCH

	2:00 - 2:40			Invited Lectures (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Tomislav Rovis (Colorado State University)
	*11-IL-1*			Professor Greg Fu, Massachusetts Institute of Technology, U.S.A.
				Recent Advances in Palladium-Catalyzed Coupling Reactions

	Section B			(Room A-102 Clark) Chair: Dr. Joseph Flisak (Glaxo SmithKline)
	*11-IL-2*			Professor Thorsten Bach, Technische Universität München, Germany
				New Synthetic Routes to Heterocyclic Natural Products

	Section C			(Room A-103 Clark) Chair: Professor Toshiyuki Kan (University of Tokyo)
	*11-IL-3*			Professor Jan Bergman, Karolinska Institute, Sweden
				Synthesis of Some Marine Indole Alkaloids

	Section D			(Room A-104 Clark) Chair: Professor Yian Shi (Colorado State University)
	*11-IL-4*			Professor Lixin Dai, Shanghai Institute of Organic Chemistry, China
				On the Regioselectivity of Asymmetric Intermolecular Heck Reaction with Planar Chiral Diphosphineoxazoline Ferrocenyl Ligands

	2:40 - 3:00			Short Oral Sessions (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Tomislav Rovis (Colorado State University)
	*11-OR-1*			Total Synthesis of Nakadomarin A
				T. Nagata, M. Nakagawa, A. Nishida (Chiba University)

	Section B			(Room A-102 Clark) Chair: Dr. Joseph Flisak (Glaxo SmithKline)
	*11-OR-2*			Syntheses of the Azatricyclic Cores ABC and ACE-Rings of the Madangamine Alkaloids
				N. Yamazaki, T. Kusanagi, J. Inoue, C. Kibayashi (Tokyo University of Pharmacy and Life Sciences)

	Section C			(Room A-103 Clark) Chair: Professor Toshiyuki Kan (University of Tokyo)
	*11-OR-3*			Total Synthesis of Spiro-Heterocyclic Biologically Intriguing γ-Lactam Natural Products
				S. Aoki, T. Oi, K. Takao, K. Tadano (Keio University)

	Section D			(Room A-104 Clark) Chair: Professor Yian Shi (Colorado State University)
	*11-OR-4*			Synthesis of Mappicine Ketone (Nothapodytine B) by Means of Aryl Radical Cyclization onto Enamides
				I. Kato, M. Higashimoto, O. Tamura, H. Ishibashi (Kanazawa University)

	3:00 - 3:30			BREAK

	3:30 - 3:50			Short Oral Sessions (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Tomislav Rovis (Colorado State University)
	*11-OR-5*			Total Synthesis of Optically Active Tetrodotoxin
				N. Ohyabu, T. Nishikawa and M. Isobe (Nagoya University)

	Section B			(Room A-102 Clark) Chair: Dr. Joseph Flisak (Glaxo SmithKline)
	*11-OR-6*			Construction of Cyclic Carbonates from Propargylic Carbonates and Phenol Using Palladium-Catalyzed Cascade Reaction
				M. Yoshida, M. Fujita and M. Ihara (Tohoku University)

	Section C			(Room A-103 Clark) Chair: Professor Toshiyuki Kan (University of Tokyo)
	*11-OR-7*			Pincer Auxiliaries to Force Difficult Lactamizations
				J.H. van Maarseveen, H. Bieräugel, O.D. Wim, J.N. Meester, H.E. Schoemaker, H. Himestra (University of Amsterdam)

	Section D			(Room A-104 Clark) Chair: Professor Yian Shi (Colorado State University)
	*11-OR-8*			Pd-Catalyzed Synthesis of Functional Building Blocks from Acetylene-Containing Amino Acids
				B.C. J. van Esseveldt, F.L. van Delft and F.P.J.T. Rutjes (University of Nijmegen)

	3:50 - 4:30			Invited Lectures (Sections A, B, C, D)
	Section A			(Room A-101 Clark) Chair: Professor Tomislav Rovis (Colorado State University)
	*11-IL-5*			Professor Albert S.C. Chan, The Hong Kong Polytechnic University, China
				Chiral Dipyridylphosphines and their Application in Catalytic Asymmetric Hydrogenation Reactions

	Section B			(Room A-102 Clark) Chair: Dr. Joseph Flisak (Glaxo SmithKline)
	*11-IL-6*			Professor Saverio Florio, Università di Bari, Italy
				Novel Oxazoline-Mediated Synthesis of Heterocycles

	Section C			(Room A-103 Clark) Chair: Professor Toshiyuki Kan (University of Tokyo)
	*11-IL-7*			Professor Marisa C. Kozlowski, The University of Pennsylvania
				Progress Towards the Synthesis of Purpuromycin and Nigerone

	Section D			(Room A-104 Clark) Chair: Professor Yian Shi (Colorado State University)
	*11-IL-8*			Dr. Bruce Pearlman, Pfizer, Inc., U.S.A.
				Development of a Process for Commercial Scale Production of a Heterocyclic Compound

	4:30 - 5:10			Invited Lectures (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Tomislav Rovis (Colorado State University)
	*11-IL-9*			Professor Shuji Kanemasa, Kyushu University, Japan
				Enantioselective Michael Additions Through Double Catalytic Activation Using Chiral Lewis Acid and Amine Catalysts

	Section B			(Room A-102 Clark) Chair: Dr. Joseph Flisak (Glaxo SmithKline)
	*11-IL-10*			Professor Michael Harmata, University of Missouri-Columbia, U.S.A.
				Synthesis and Chemistry of 2,1-Benzothiazines

	Section C			(Room A-103 Clark) Chair: Professor Toshiyuki Kan (University of Tokyo)
	*11-IL-11*			Professor Oliver Reiser, Universität Regensburg, Germany
				Asymmetric Cyclopropanation of Furans as Key Step for the Synthesis of Natural Products and Analogs

	Section D			(Room A-104 Clark) Chair: Professor Yian Shi (Colorado State University)
	*11-IL-12*			Professor Biao Jiang, Shanghai Institute of Organic Chemistry, China
				Total Synthesis and Biological Evaluation of marine Bis(indole) Alkaloids and Analogues

5:10 - 6:30					POSTER SESSION I

11-PO-1					Synthesis of 3,3'-Diindolylmethane Using Several Energy Sources	101
					J. Guillermo Penieres C., J. Manuel Aceves H, J. Guadalupe Garcia E., César Sandoval c., Francisca, García L.

11-PO-2					Synthesis, Photochromic Properties of Aryl-, Heteroaryl- and Biphenyl-Linked Biphenyl-Linked 3H-naphthol[2,1-b]pyrans	102
					Stuart Aiken, Christopher D. Gabbutt, B. Mark Heron

11-PO-3					[2+2] Photocycloaddition Reactions of Uracils as an Efficient Route to Cyclobutane β-Aminoacids	103
					David J. Aitken, Sophie Faure, Christine Gauzy, Elisabeth Pereira, Bertrand Saby

11-PO-4					A Practical Synthesis of Arylbenzthioamide Based on Friedel-Crafts Reaction with Potassium Thiocyanate in Methanesulfonic Acid	104
					Shinji Aki, Takafumi Fujioka, Masashi Ishigami, Jun-ichi Minamikawa

11-PO-5					An Improved Synthesis of New Aldehydes in the Pyranone Series	105
					Rufine Akué Gédo, Benoît Rigo, Jean-Pierre Hénichart

11-PO-6					Mechanism of Formation of a Pinacol Like Dimer	106
					Rufine Akué Gédo, Daniel Couturier, Benoît Rigo

11-PO-7					Studies Toward the total Synthesis of TMC-95A/B	107
					Brian K. Albrecht, Robert M. Williams

11-PO-8					New Methods of Palladium-Catalyzed Cross Coupling between Organometallics, Heteroraromatic Thioethers	108
					France-Aimée Alphonse, Franck Suzenet, Anne Keromnes, Bruno Lebret, Gérald Guillaumet

11-PO-9					Design, Synthesis of 5-Substituted 4,7-Dihydro-5H-thieno[2,3-c]pyrans as Classical Competitive Inhibitors of Protein-Tyrosine Phosphatase Beta	109
					Ida Katrine Lund, Henrik Sune Andersen, Lars Fogh Iversen, Ole Hvilsted Olsen, Karin Bach Møller, Yu Ge, Daniel D. Holsworth, Michael Newman, Frank Axe, Niels Peter Hundahl Møller

11-PO-10					Vicarious Nucleophilic Alkylations of 3-Nitropyridines	110
					Jan M. Bakke, Harald Svensen, Einar J. Andreassen

11-PO-11					Synthesis, Electrochemical Properties of Highly Electron Rich Compounds: 3,3'-, 4,4'-Dimethoxy-2,2'-bipyrroles 3-, 3,4-Aminopyrroles	111
					Sergiy Anikin, Andreas Merz

11-PO-12					Pyrrole Derivatives via Catalytic Hydroamination of 1,4-, 1,5-Diynes	112
					Douglas Armstrong, Bala Ramanathan, Yanhui Shi, Aaron L. Odom

11-PO-13					Domino Diels-Alder Reaction of Furan at High Pressure	113
					Kota Asanuma, Koji Kumamoto, Motoo Shiro, Hiyoshizo Kotsuki

11-PO-14					A New Strategy for Asymmetric Synthesis Exploiting Oxime Ethers, Application to Enantioselective Syntheses of G-Protein Couple Receptor Ligands	114
					Masakazu Atobe, Naoki Yamazaki, Chihiro Kibayashi


11-PO-15					Reaction of Thioamides with Methyl 2,4-Dioxovalerate as a Novel Approach to Pyrrolo[3,4-c]pyridine	115
					Vasiliy A. Bakulev, Vera S. Berseneva, Wim Dehaen

11-PO-16					Synthesis of Some New Bis-(5-hydroxy-4-(5-aryl-3-isoxazolyl)1-phenoxy) Methanes (I), Bis-(5-hydroxy-4-(1-phenyl-5-aryl-3-pyrazolyl)1-phenoxy) Methanes (II), Their Applications as Antibacterial, Antifungal Agents	116
					P.M. Band, V.S. Jamode

11-PO-17					Calix[4]pyrroles Having Stable Cone Conformations. A Computational Choice of Synthetic Targets	117
					Harold D. Banks

11-PO-18					cis-Dithienylethenes via Dithienylacetylenes	118
					L.I. Belen'kii, V.Z. Shirinian, G.P. Gromova, A.V. Kolotaev, M.M. Krayushkin

11-PO-19					Synthesis of Anti-HIV CADA Compounds, Quantitative Structure-Activity Relationships for CD4 Down-Modulation	119
					Thomas W. Bell, Kaka Dey, Qi Jin, Meinrado F. Samala, Andrej Sodoma, Kurt Vermeire, Erik De Clercq, Dominique Schols

11-PO-20					Synthesis, Reactivity of N-hydroxy-2-aminoindoles	120
					Michel Belley, Peter Duspara, Effiette Sauer, Pascal Dubé

11-PO-21					Synthesis of Cytokinin Analogs as Potential Plant Growth Stimulators	121
					Tom Christian Berg, Lise-Lotte Gundersen

11-PO-22					Nucleophilic Substitution in Some 5-Halopyrimidines	122
					Evgeniy V. Blyumin, Hans Neunhoeffer, Yulian M. Volovenko

11-PO-23					[3,3]Sigmatropic Rearrangements of 2,4-Dinitrophgenyl Oximes	123
					Peter H. Boyle, Haslin Dato Paduka Ali, Thomas J. McDonald

11-PO-24					Synthesis of Antimycobacterial 6-Aryl-9-benzylpurines	124
					Morten Brændvang, Lise-Lotte Gundersen

11-PO-25					Cytotoxic Activity, Synthesis of 6-Alkenyl, 6-Alkynylpurines	125
					Anders Bråthe, Lise-Lotte Gundersen, Frode Rise, Jon Nissen-Meyer, Bjørn Spilsberg

11-PO-26					Studies Towards the Total Synthesis of Microsclerodermin G	126
					Cameron M. Burnett, Robert M. Williams

11-PO-27					Radical Aromatic Substitution on Nitrogen Heterocycles	127
					Jeffrey H. Byers, Gregory W. Woo, Anne J. Dewitt, Michael P. Duff, Christopher G. Nasveschuk

11-PO-28					Lithiated Styrene Oxides: Influence of the C-Li Bond Nature on Their Reactivity	128
					Vito Capriati, Saverio Florio, Renzo Luisi, Luana Possessere

11-PO-29					Studies on the Asymmetric Synthesis of Spiroquinazoline	129
					Siyuan, Chen, Robert M. Williams

11-PO-30					Studies Toward the Total Synthesis of Lemonomycin	130
					Yuyin Chen, Robert M. Williams
11-PO-31					Synthesis of Novel Nucleoside Analogues Based on a Spiroacetal Framework	131
					Ka Wai Choi, Margaret A. Brimble, James E. Robinson

11-PO-32					A New Synthesis of the Functionalized Indoles by the Allene-Mediated Electrocyclic Reaction Involving the Pyrrole 2,3-Bond	132
					Tominari Choshi, Maho Hirayama, Junko Nobuhiro, Satoshi Hibino

11-PO-33					Synthesis of Pyrazinone Thrombin Inhibitor Mediated by 2-Pyridylthioimidate-ZnCl₂ Complexes	133
					John Y.L. Chung, Raymond Cvetovich, Fuh-Rong Tsay, Peter Dormer, Lisa DiMichele, Bing Mao, Robert Wenslow

11-PO-34					Practical Synthesis of Highly Optical Active (R)-Aryloxyphenoxy-2-propionates Through Walden Inversion	134
					Kun Hoe Chung, Sung Kon Ryu, Young Kwan Ko, Hae Sung Chang, Jae Wook Ryu, Jae Chun Woo, Dong Wan Koo, Dae-Whang Kim

11-PO-35					Solid Phase Synthesis of Lamellarins	135
					Pablo Cironi, Ignacio Manzanares, Fernando Albericio, Mercedes Álvarez

11-PO-36					Studies Toward the Total Synthesis of (-)-Neodysiherbaine	136
					Matthew J. Cook, Timothy Gallagher

11-PO-37					Synthetic Approaches Towards Potent α_vβ₃ Integrin Antagonists	137
					Cameron J. Cowden, Brian C. Bishop, Karel M.J. Brands, Antony J. Davies, Ulf-H Dolling, Deborah C. Hammond, David R. Lieberman, Sarah E. Newman

11-PO-38					Synthetic Studies Towards Paraherquamide F and Stephacidin A	138
					Rhona J. Cox, Robert M. Williams

11-PO-39					Acetoxy(methoxy)carbene	139
					Wojech Czardybon, John Warkentin, Nick Henry Werstiuk

11-PO-40					Stereo-, Regioselective Synthesis of Alkyl-, Phenyl-Substituted β-Aminocyclopropanecarboxylates	140
					Sven Mangelinckx, Norbert De Kimpe

11-PO-41					New Reduction of Pyrrolin-2-ones Towards Functionalised Pyrroles	141
					Guido Verniest, Norbert De Kimpe

11-PO-42					Comparative Reactivities of Halogenated Pyrimidines	142
					Thomas J. Delia, John D. Sivey, Geneice F. McCloud

11-PO-43					Functionalized Indolylfulgimides - Synthesis, Photochemical Properties	143
					Steffen Dietrich, Karola Rück-Braun

11-PO-44					Synthesis of Arylamino-Substituted 2-Chloropyridines via Regioselective Palladium-Catalyzed Amination Under Mild Reaction Conditions	144
					Bert U.W. Maes, Tim H.M. Jonckers, Kristof T.J. Loones, Guy L.F. Lemière, Roger A. Dommisse, A. Haemers

11-PO-45					Synthesis of C-Glycoside Containing Natural Products via Oxocarbenium Ions	145
					Julie M. Lukesh, Patrick B. Greer. Luping Liu, William A. Donaldson

11-PO-46					Butynyl Ether Derivatives as Inhibitors of TACE	146
					J. Levin, X. Du, J.D. Albright, J. Chen, E. Delos Santos, M. Du, F.C. Nelson, T. Cummons, R Mulvey, S. Skala, A. Sung, J. Xu, G. Jin, R Cowling, D. Barone, RA. Black, J.S. Skotnicki

11-PO-47					FR900482 Analogues as Tools in Biology	147
					Pascal Ducept, Robert M. Williams

11-PO-48					The Interaction of 1,2-bis(2,5-dimethylthienyl-3)-2-hydroxyethanone-1 with Sulfur-Containing Nucleophiles	148
					Mikhail M. Krayushkin, Boris V. Lichitsky, Aleksei P. Mikhalev, Sergey N. Ivanov, Denis V. Kozhinov, Arkady A. Dudinov

11-PO-49					Synthesis of the Thrombin Inhibitor 2-{3-[(2,2-Difluoro-2-(2-pyridyl)ethyl)amino]-6-chloro-2-oxohydro pyrazinyl}-N-[(3-fluoro(2-pyridyl))methyl]acetamide Khateeta Emerson	149

11-PO-50					Synthesis of Quinone Epoxides, Rearrangement to Furan-Containing Angular Quinones	150
					Jaime A. Valderrama, Omar Espinoza, M.F. Gonzalez

11-PO-51					Selective N-9 Alkylation of Guanine Using N⁷-(4-Nitrobenzyl)guanine	151
					Györgyi Ferenc, Péter Forgó, Zoltán Kele, Lajos Kovács

11-PO-52					A Convenient Synthesis of 6H-Chromeno[2,3-d]pyrimidines	152
					Maria C. Fonseca, Margarita Romero, José M. Mendez, Blas Flores

11-PO-53					Preparation, Cyclization of 2-Amidoacroleins: Application to the Synthesis of Alkaloid Natural Products	153
					James R. Fuchs, Thomas J. Greshock, Jun-Ho Maeng, Raymond L. Funk

11-PO-54					*2-exo-Methyl-3-endo-phenyl-5-norbornene-2-carboxyaldehyde: Highly Effective, Recycable Auxiliary for Desymmertrization of meso-Diols*	154
					Hiromichi Fujioka, Tetsuya Fujita, Naoyuki Kotoku, Yasushi Nagatomi, Yasuyuki Kita

11-PO-55					Synthetic Study of Pyridinium Retinoids as Probe Molecules for G-Protein-Coupled Receptor	155
					Takume Furuta, Yoshiki Matsuzawa, Tomohiro Asakawa, Kiyoshi Tanaka

11-PO-56					Transformations of 3-Acylchromones into Alkenyl, Allenyl Chromones	156
					Dan E. Daia, David S. Clarke, Christopher D. Gabbutt, John D. Hepworth, B. Mark Heron

11-PO-57					Amino Isoxazole Derivatives as Building Blocks for Pyrimidoblamic Acid Analogs and Other Pyrimidine Derivatives	157
					Isra Gbara, Gury Zvilichovsky

11-PO-58					Preparation of 1,4-bis(5-aminobenzimidazol-2-yl)benzene - Monomer for Polyamidobenzimidazole Polymers and Fibers	158
					Mark Gelmont

11-PO-59					Unusual Reaction of 4-Bromomethyl Coumarin with Hydrazine Hydrate, Phenyl Hydrazine in Ethanol, Acetic Acid Medium: New Method of Synthesis of 3-Oxo-a4-benzopyridazine	159
					Manjunath Ghate, Manohar V. Kulkarni

11-PO-60					Heterocyclic Analogues of the Iron-Only Hydrogenases	160
					Maya S. Singh, Richard S. Glass

11-PO-61					Stereoselective Synthesis of Alkenyl-β-Lactams by Pd-Catalyzed [2+2] Carbonylative Cycloaddition	161
					Luigino Troisi, Saverio Florio, Catia Granito, Luisella De Vitis

11-PO-62					Synthetic Efforts Toward Asperparaline A and Biosynthetic Studies	162
					Chandele R. Gray, Juan F. Sanz-Cervera, Robert M. Williams

11-PO-63					Studies Towards the Total Synthesis of Okaramine B	163
					Alan W. Grubbs, Robert M. Williams

11-PO-64					Regioselective N-9 Arylation of Purines Employing Arylboronic Acids in the Presence of Cu(II)	164
					Anne Kristin Bakkestuen, Lise-Lotte Gundersen

11-PO-65					Synthesis and Cycloaddition of Azomethine Imines Containing [1,2,4]triazine Ring	165
					György Hajós, Zsuzsanna Riedl, Csilla Gróf, Branko Stanovnik

11-PO-66					Novel Synthesis of Naphthobenzazepines from N-bromobenzylnaphthylamines by Regioselective C-H Activation Utilizing Intramolecular Coordination of Amine to Pd	166
					Takashi Harayama, Tomonori Sato, Akihiro Hori

11-PO-67					Total Synthesis of Antitumor Marine Alkaloid, Discorhabdin A	167
					Hirofumi Tohma, Yu Harayama, Miki Hashizume, Yorito Kiyono, Minako Iwata, Masahiro Egi, Yasuyuki Kita

11-PO-68					Synthetic Studies of Indole Alkaloids Based on Indolylborates	168
					Minoru Ishikura, Hidekazu Takahashi, Miyako Hasunuma

11-PO-69					Lewis Acid-Mediated Asymmetric 1,3-Dipolar Cycloadditions of Nitrile Oxide	169
					Hidetoshi Yamamoto, Saori Hayashi, Akiko Nishida, Michihiko Noguchi, Shuji Kanamasa

11-PO-70					The Synthesis of Novel Thienoisoxazole Piperidines and Thienopyrazole Piperazines	170
					James A. Hendrix, David Stefany, Sarah L. Brooks, George E. Lee, Jean-François Sabuco, Eric MacMillan, Leila Albers, Shelley Pavlek, Nicola Collar, Ephraim Vidal

11-PO-71					Observations on the Synthesis, Reactivity of Photochromic Naphthopyrans	171
					Christopher D. Gabbutt, B. Mark Heron, David A. Thomas

11-PO-72					The Absolute Configuration of (+)-Oxopropaline D by Theoretical Calculation of Specific Rotation, Asymmetric Synthesis	172
					Satoshi Hibino, Takeshi Kuwada, Miyako Fukui, Tominari Choshi, Junko Nobuhiro, Toshiyuki Hata, Yukio Ono

11-PO-73					The Asymmetric Synthesis of 1-Substituted Cyclohex[b]indoles	173
					M.C. Hillier, J.-F. Marcoux, B.A. Suhr, E.J.J. Grabowski, R.D. Tillyer

11-PO-74					A Second-Generation Synthesis of Zaragozic Acid C	174
					Yuuki Hirata, Takahiro Kurosaki, Masahiro Anada, Seiichi Nakamura, Shunichi Hashimoto

11-PO-75					Synthesis of 2,8-Disubstituted 9-Benzyladenines with Interferon-Inducing Activity	175
					Kosaku Hirota, Kazunori Kazaoka, Hironao Sajiki

11-PO-76					Use of Phenacylesters of Substituted Benzoic Acid for Synthesis of Derivatives of 2-Phenyl-3-hydroxy-4(1H)-quinolones	176
					Jan Hlaváč, Pavel Hradil, Miroslav Soural, Lucie Spáǒilová

11-PO-77					Synthesis of a Potential Intermediate for Pseudomonic Acid B by Means of Means of Enantioselective Deprotonation Strateg y	177
					Toshio Honda, Nobuaki Kimura

11-PO-78					Studies on Taxol Biosynthesis. Preparation and Tritium Labelling of Biosynthetic Intermediates by Deoxygenation of a Taxadiene Tetra-Acetate Obtained from Japanese Yew	178
					Tohru Horiguchi, Christopher D. Rithner, Rodney Croteau, Robert M. Williams

11-PO-79					Elaboration of 9- and 8-Oxa-1-azabicyclo[4.2.1]nonanes into Chiral Azetidines	179
					Miklós Hornyák, Petra Pádár, Péter Forgó, Zoltán Kele, Nicola M. Howarth, Lajos Kovács

11-PO-80					A Highly Effective Preparation of an α_vβ₃ Antagonist Part I. Synthesis of Tetrahydronaphthyridine	180
					Yi Hsiao, N. Yasuda, M. Palucki, N. Rivera, M.S. Jensen, D.L. Hughes

11-PO-81					3-Indolyl Methylphosphonates as Indicator for Enzyme-Based Decontaminant of Organophosphates	181
					Fu-Lian Hsu, Tu-chen Cheng, Frederic J. Berg, Vipin K. Rastogi

11-PO-82					Asymmetric Syntheses of Pharmaceutically Interesting Piperidines Based a Chiral New Piperidine Synthon	182
					Liang-Xian Liu, Bang-Guo Wei, Pei-Qiang Huang

11-PO-83					An Unexpected Formylation of a Substituted Furan	183
					Walter Hübsch

11-PO-84					New Pyrimidine- and Fluorene-Containing Oligo(arylenes)	184
					Greg Hughes, Changsheng Wang, Martin R. Bryce

11-PO-85					A Biosynthesis Inspired Diels-Alder Route to the Amythiamycins	185
					Rachael A. Hughes, Christopher J. Moody

11-PO-86					A Novel, Convenient Synthesis of 4-Halobutyraldehyde Acetals	186
					John A. Hyatt

11-PO-87					Synthesis of N-Acetylneuraminic Acid Derivatives Structurally Modified at C-4 Position and Their Behavior Towards Sialidase from Human Parainfluenze Virus Type I	187
					Kiyoshi Ikeda, Satoru Kitani, Kazuki Sato, Chika Hosokawa, Takashi Suzuki, Yasuo Suzuki, Kiyoshi Tanaka, Masayuki Sato

11-PO-88					Synthesis of Optically Active 2,3-Dihydrobenzofuran Derivatives Through a Combination Strategy of Iron(III)-Catalyzed Reaction and Enzymatic Reaction	188
					Toshiyuki Itoh, Kimio Kawai, Shuichi Hayase, Hiroyuki Ohara

11-PO-89					New Synthesis of 3-Heteraryl-7-Azacoumarines	189
					Alexandre V. Ivachtchenko, Sergiy M. Kovalenko, Iryna O. Zhuravel, Valentyn P. Chernykh

11-PO-90					Convergent Synthesis of Lamellarin Alkaloids	190
					Masatomo Iwao, Naotaka Fujikawa, Tsutomu Fukuda, Fumito Ishibashi

11-PO-91					Synthesis and Pharmacology of 3-(4-Arylpiperazin-1-ylaklyl)-Uracils as Uroselective α_1A-Antagonists	191
					S. Jaime-Figueroa, L. Arias, R. Chan, D.E. Clarke, T.R. Elworthy, AP.D.W. Ford, A Guzman, J.R., F.J. Lopez, D.J. Morgans Jr., F. Padilla, A. Perez-Medrano, C. Quintero, M. Romero, L. Sandoval, S.A Smith, T.J. Williams, D.R. Blue

11-PO-92					Efficient Synthesis of the Clinical Agent Cladribine (2-Chloro-2'-deoxyadenosine) from 2'-Deoxyguanosine	192
					Zlatko Janeba, Paula Francom, Morris J. Robins

11-PO-93					Study Towards the Total Synthesis of Ecteinascidin-743	193
					Wei Jin, Robert M. Williams

11-PO-94					Remarkable Reactivity Enhancement Through Sb-N Non-Bonding Interaction in Azastibocine: Palladium Catalyzed C-C Bond Forming Reaction with Organic Halides	194
					Naoki Kakusawa, Kentaro Ymaguchi, Jyoji Kurita

11-PO-95					Synthesis, Physical Properties and Formation of Metal Complexes of Unsaturated Thiacrown Ethers	195
					Nobumasa Kamigata, Takahiro Tsuchiya, Kazunori Hirabayashi, Toshio Shimizu

11-PO-96					Oxyoxazolidinones as a New Synthetic Auxiliary	196
					Akio Kamimura, Yoji amata

11-PO-97					Solution and Solid-Phase Generation of Multifunctionalized 2-Amino-6-H-1,3-thiazine Libraries	197
					Gernot A. Strohmeier, C. Oliver Kappe

11-PO-98					Diastereo- and Enantioselective Cycloaddition of Azomethine Ylides Generated from N-Alkylideneglycine Esters Catalyzed by Chiral Copper-Phosphine Complexes	198
					Yukihiro Kasano, Yoji Oderaotoshi, Satoshi Minikata, Mitsuo Komatsu

11-PO-99					Synthesis of New 1,3-Linked 1,4-Dihydropyridines Containing the p-Amino-L-Phenylalanine Residue and Their Enantioselective Reducing Ability	199
					Akira Katoh, Koji Takano, Ryota Saito

11-PO-100					Palladium Catalysts in Carbohydrate Synthesis	200
					Hirotoshi Kawabata, Kanako Yamada, Masahiko Hayashi

12-PO-121					New Protection Strategy for the Synthesis of Aminoalkyl Azoles: Synthesis of 5-Aminoalkyl-1,2,4-Oxadiazoles	221
					Volodymyr Kysil, Alexander Khvat, Alexander Ivachtchenko

12-PO-122					About Isoxazolines and N-O-Bond Cleavages	222
					Markku Lager, Karola Rück-Braun

12-PO-123					Docking of Indolo- and Pyrrolo-Pyrimidines to DNA. New DNA-Interactive Polycycles from 2-Amino-Indoles/Pyrroles and BMMA	223
					Antonino Lauria, Diana Patrizia, Paola Barraja, Alessandra Montalbano, Gaetano Dattolo, Girolamo Cirrincione, Anna Maria Almerico

12-PO-124					New Tetracyclic Ring System of Biological Interest. Indolo[3,2-e][1,2,3]triazolo[1,5-a]pyrimidine Through Domino Reactions of 2-Azidoindole	224
					Antonino Lauria, Chiara Patella, Diana Patrizia, Paola Barraja, Alessandra Montalbano, Gaetano Dattolo, Girolamo Cirrincione, Anna Maria Almerico

12-PO-125					Stereoselective Reduction of 2-Acylaziridines: An Efficient Synthesis of D-erythro-Sphinganine and Safingol from a Common Intermediate	225
					Jung Min Yun, Taebo Sim, Heung Sik Hahm, Won Koo Lee, Hyun-Joon Ha

12-PO-126					Overcrowded 1,8-Diazafluorenylidine-Chalcoxanthenes Series	226
					Amalia Levy, Shmuel Cohen, Israel Agranat

12-PO-127					A Nitro-Aldol Approach to the Synthesis of Cylindrospermopsin	227
					Ryan E. Looper, Robert M. Williams

12-PO-128					Synthesis of Tetracyclic Angular Heterocyclic Quinones with Potential Biological Activities	228
					Ricardo A. Tapia, Claudio López, Jaime Valderrama

12-PO-129					Push-Pull Molecules Derived from Acridine, Benzothiazole with N L O Properties. Photonic Crystals	229
					Albert Molinos, Francisco López-Calahorra, Dolores Velasco, Mariano Martínez

12-PO-130					N-Arylation of Carbazoles Under Bronze Catalyst	230
					Meritxell Martínez-Palau, Eva Perea, Francisco López-Calahorra, Dolores Velasco

12-PO-131					On the Addition of Lithiated 2-Alkyloxazolines to Nitrones: Stereoselective Synthesis of Oxazetidines and Isoxazolidinones	231
					Vito Capriati, Saverio Florio, Renzo Luisi, Eliana Piccolo, Teresa Vista

12-PO-132					Design and Synthesis of Substances Possessing of Cardio-Vascular Action on the Base of Arylalkylamines and Nitrogen and Oxygen-Containing Heterocycles Conjugated with Them	232
					Eduard A. Margaryan, Hambardzum G. Khachatryan

12-PO-133					Synthesis of Tetrahydrobenzazepine and Isoquinoline Derivatives Possessing of Anticholinesterase Action	233
					Eduard A. Margaryan, Asya A. Aghekyan, Zhasmina S. Arustamyan, Ruzanna E. Margaryan, Levon Sh. Pirdjanov, Hambardzum G. Khachatryan

12-PO-134					Novel Phosphorus Ylides from ANRORC and Ring Cleavage Reactions of 3-(Aryliminomethyl)chromones	234
					Christopher D. Gabbutt, B. Mark Heron, Craig A. Mars, Mark E. Light, Michael B. Hursthouse

12-PO-135					Synthesis and Powdery Mildew Activity of Novel Substituted Bicyclic Oxazinones and Thiazinones	235
					James F. Bereznak, Eric A. Marshall

12-PO-136					A Simple Method for the Preparation of Pyrrolo[2,3-d]pyrimidines and 2H-1,2,3-Triazolo[4,5-d]pyrimidines from Conjugated Sulfilimines	236
					Nobuaki Matsumoto, Masahiko Takahashi

12-PO-137					Synthesis and Properties of Macrocyclic Compounds Bearing Thiourea Moieties	237
					Noboru Matsumura, Yasuyuki Okumura, Satoshi Murakami, Hajime Maeda, Kazuhiko Mizuno

12-PO-138					New Syntheses and Applications of Pyrrolo-, Indolo-Carbazoles	238
					Lynne A. Crawford, Hamish McNab, Andrew R. Mount, Stuart I. Wharton

12-PO-139					Bithiophenes, Bipyrroles and Mixed Heterocycles	239
					Christina Rehm, Jürgen Kronberger, Andreas Merz

12-PO-140					Friedel-Crafts Reaction of Indole-2,3-dicarboxylic Anhydride with Anisoles	240
					Yasuyoshi Miki, Yasuhiko Tsuzaki

12-PO-141					Aziridination of Olefins in Water Utilizing Chloramine-T-I₂-silica System	241
					Satoshi Minakata, Yoshiaki Inda, Yoji Oderaotoshi, Mitsuo Komatsu



	August 12 (Tuesday)

	9:00 - 12:20 Plenary Lectures (Main Ballroom, Lory Student Center, 2^nd Floor)

	9:00	Chair: Professor Alan J. Kennan (Colorado State University, USA)
		*12-PL-4*
		Professor M. Reza Ghadiri Scripps Research Institute, USA
		Self-Assembling Peptide Nanotubes: Design and Biological Applications

	10:00	Chair: Professor Robert M. Williams (Colorado State University)
		*12-PL-5*
		Professor Cynthia J. Burrows University of Utah
		Spirocyclic Nucleosides from Oxidative DNA Damage

	11:00 - 11:20		BREAK
	11:20	Chair: Dr. Michael J. Martinelli (Eli Lilly & co.)
		*12-PL-6*
		Professor Dale Boger Scripps Research Institute, USA
		Azadiene Diels-Alder Reactions: Scope and Applications

	12:20		LUNCH

	2:00 - 2:40			Invited Lectures (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Robert M. Williams (Colorado State University)
	*12-IL-13*			Professor Oliver Kappe, Karl-Franzens-University Graz, Austria
				Rapid Microwave-Assisted Protocols for the Generation and Decoration of Privileged Heterocyclic Scaffolds

	Section B			(Room A-102 Clark) Chair: Professor Louis S. Hegedus (Colorado State University)
	*12-IL-14*			Professor Anthony G.M. Barrett, Imperial College, U.K.
				Peripherally-Functionalized Porphyrazines: Novel Metallomacrocycles with Broad, Untapped Potential

	Section C			(Room A-103 Clark) Chair: Dr. Michael J. Martinelli (Eli Lilly & Co.)
	*12-IL-15*			Dr. Paul Reider, Amgen, Inc., U.S.A.
				Synthesis of Carbapenem Antibiotics and Other Complex Heterocycles

	Section D			(Room A-104 Clark) Chair: Dr. Joe Guiles (Replidyne, Inc.)
	*12-IL-16*			Professor Dieter Hoppe, Westfälische Wilhelms-Universität Münster, Germany
				Enantioselective Synthesis of Saturated Heterocycles via Stereoselective Lithiation

	2:40 - 3:00			Short Oral Sessions (Sections A, B, C, D)

	Section A			(Room A-101Clark) Chair: Professor Robert M. Williams (Colorado State University)
	*12-OR-9*			Synthetic and Medicinal Applications of Imidazoline Scaffolds
				J.J. Tepe, M. Peddibhotla, T.A. Landsdell, V. Aharma and S. Jayakumar (Michigan State University)

	Section B			(Room A-102 Clark) Chair: Professor Louis S. Hegedus (Colorado State University)
	*12-OR-10*			Multiple Ring Closing Metathesis Reactions in the Synthesis of Novel Heterocyclic Compounds
				D. J. Wallace (Merck & Co.)

	Section C			(Room A-103 Clark) Chair: Dr. Michael J. Martinelli (Eli Lilly & Co.)
	*12-OR-11*			Total Synthesis of Brevetoxin-B
				T. Nakata, G. Matsuo, K. Kawamura, N. Hori, H. Matsukura (RIKEN)

	Section D			(Room A-104 Clark) Chair: Dr. Joe Guiles (Replidyne, Inc.)
	*12-OR-12*			Stereoselective Synthesis of 2,4-cis-Substituted Pyrrolidines Through a Free Radical Sulfur to Carbon Translocation Reaction
				M.D. Bachi, E.E. Korshin, Y.V. Bilokin, H. Zheng (Weizmann Institute of Science)

	3:00 - 3:30			BREAK

	3:30 - 3:50			Short Oral Sessions (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Robert M. Williams (Colorado State University)
	*12-OR-13*			Total Synthesis of (-)-Ephedradine A
				T. Kan, W. Kurosawa, T. Fukuyama (University of Tokyo)

	Section B			(Room A-102 Clark) Professor Louis S. Hegedus (Colorado State University)
	*12-OR-14*			Efficient Cyclizations of Medium Ether Rings Using SmI₂
				F. Matsuda, H. Tamiya (Hokkaido University)

	Section C			(Room A-103 Clark) Chair: Dr. Michael J. Martinelli (Eli Lilly & Co.)
	*12-OR-15*			Application of Radical Cyclization Studies Toward Assemblage of the D-Ring of the Aspidosperma Alkaloid Skeleton
				P. Rashatasakhon, A. Padwa (Emory University)

	Section D			(Room A-104 Clark) Chair: Dr. Joe Guiles (Replidyne, Inc.)
	*12-OR-16*			Progress Towards the Synthesis of Bioactive Alkaloids from Chiral Vinyl Epoxides
				S.G. Pyne (University of Wollongong)

	3:50 - 4:30			Invited Lectures (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Robert M. Williams (Colorado State University)
	*12-IL-17*			Professor Raymond L. Funk, Pennsylvania State University, U.S.A.
				Preparation and Cyclization of 2-Amidoacroleins: Application to the Synthesis of Alkaloid Natural Products

	Section B			(Room A-102 Clark) Chair: Professor Louis S. Hegedus (Colorado State University)
	*12-IL-18*			Professor Janusz Jurczak, Warsaw University, Poland
				Synthesis of Heteromacrocyclic Compounds Using Dynamic Combinatorial Chemistry Methods

	Section C			(Room A-103 Clark) Chair: Dr. Michael J. Martinelli (Eli Lilly & Co.)
	*12-IL-19*			Professor Girolamo Cirrincione, University of Palermo, Italy
				Pyrrolo[2,1-d][1,2,3,5]tetrazine-4(3H)-ones with Potent Antitumor Activity

	Section D			(Room A-104 Clark) Chair: Dr. Joe Guiles (Replidyne, Inc.)
	*12-IL-20*			Professor Binne Zwanenburg, University of Nijmegen, The Netherlands
				Functionalized Small-Ring Heterocycles in Synthesis and Catalysis

	4:30 - 5:10			Invited Lectures (Sections A, B, C, D)

	Section A			(Room A-101 Clark) Chair: Professor Robert M. Williams (Colorado State University)
	*12-IL-21*			Professor Marc L. Snapper, Boston College, U.S.A.
				New Reactions: Introducing Molecular Strain to Access Molecular Complexity

	Section B			(Room A-102 Clark) Chair: Professor Louis S. Hegedus (Colorado State University)
	*12-IL-22*			Professor Christopher J. Moody, University of Exeter, U.K.
				Synthetic Approaches to Macrocyclic Heterocyclic Peptides

	Section C			(Room A-103 Clark) Chair: Dr. Michael J. Martinelli (Eli Lilly & Co.)
	*12-IL-23*			Dr. Jos Brands, Merck & Co., U.S.A.
				The Power of Crystallization Induced Asymmetric Transformations in Efficient Syntheses of hNK-1 Receptor Antagonist MK-0869

	Seetion D			(Room A-104 Clark) Chair: Dr. Joe Guiles (Replidyne, Inc.)
	*12-IL-24*			Professor Zhi-tang Huang, Chinese Academy of Sciences, Beijing, China
				Advances in Heterocyclic Ketene Aminals

5:10 - 6:30	POSTER SESSION II

12-PO-101	Synthesis and Pharmacological Properties of Some Bis-(1-(5-Aryl-3-isoxzolnyl)2-hydroxy-4-oxyphenyl) Methanes and Bis-(1-(1-Phenyl-5-aryl-3-pyrazolinyl)2-hydroxy-4-oxyphenyl) Methanes	201
	Jayant Kaware, Pramod Band

12-PO-102	Regioselective Condensation of 1-Methyl-3-trimethylsilylimidazolidinetrione with Primary Amines	202
	Seikou Nakamura, Ikuo Kawasaki, Masami Terano, Masayuki Yamashita, Shunsaku Ohta

12-PO-103	Enantioselective Total Synthesis of (-)-Pseudophrynaminol Through Tandem Olefination, Isomerization and Asymmetric Claisen Rearrangement	203
	Tomomi Kawasaki, Atsuyo Ogawa, Yasuyuki Takashima, Masanori Sakamoto

12-PO-104	A Short Synthesis of Five Membered Ring Heterocycle in High Stereo Selectivity Without Catalyser	204
	Yango Keita, Siegfried Hünig

12-PO-105	New Scaffolds for Combinatorial Synthesis and Libraries. New Synthetic Approach to 6-Sulfamoyl-Quinoline-4-Carboxamindes	205
	Alexandre V. Ivachtchenko, Vladimir V. Kobak, Alexander V. Khvat, Caroline Williams

12-PO-106	A Novel Synthesis of 4,5-Disubstituted 6-Alkyl (and Aryl)amino-2,3-benzo-1,3a,6a-Triazapentaienes from 2,3-Disubstituted 3-(benzotriazol-1-yl)acrylaldehydes	206
	Yu Ah Choi, Kyongtae Kim

12-PO-107	Regioselective Synthesis of Novel Tricyclic Aroisoprenoid Stachybotrins	207
	Riyong Kim, Yujiro Hoshino, Kiyoshi Honda, Seiichi Inoue

12-PO-108	Pd-Catalyzed Transformation of Olefinic Oximes to Aza-Hetercycles	208
	Mitsuru Kitamura, Koichi Narasaka

12-PO-109	Convenient Synthesis of Coumarins Using Phenols and Acetylenecarboxylates	209
	Tsugio Kitamura, Kiyomi Yamamoto, Masashi Kotani, Juzo Oyamada, Yuzo Fujiwara

12-PO-110	Molecular Rearrangement of 3-Amino-1H,3H-Quinoline-2,4-Diones via the Reaction with Urea	210
	Antonin Klásek, Kamil Kořstek, Antonin Lyčka, Michal Holčapek

12-PO-111	2H-Pyran-2-Ones and Fused Pyran-2-Ones: Cycloaddition Reactions	211
	Krištof Kranjc, Siovenko Polanc, Marijan Kočevar

12-PO-112	Solvent-Free Synthesis of Benzothiazoles and 1,5-Benzothiazepines on a Solid Surface	212
	Mitsuo Kodomari, Tomohiro Noguchi, Yoshimi Tamaru, Tatsuya Yamaguchi

12-PO-113	Efficient Synthesis of α_1D Adrenoceptor Antagonist A-315456	213
	Teodozyj Kolasa, Robert Altenbach, Steven A. Buckner, Ivan Milicic, Anthony Daza, Jorge Brioni

12-PO-114	Chemo-Enzymatic Synthesis of Naturala and Unnatural 2'-Deoxynucleosides	214
	Hironori Komatsu, Hirokazu Awano, Hiroki Ishibashi, Toshihiro Oikawa, Ichirou Ikeda, Tadashi Araki

12-PO-115	Synthetic Study of Miraziridine A	215
	Hiroyuki Konno, Emi Toshiro, Hitoshi Hori

12-PO-116	Route Selection and Development for the Synthesis of N-(Azacycloalkyl) Bisindolylmaleimides: Selective Inhibitors of PKCβ	216
	Margaret M. Faul, John L Grutsch, Michael E. Kobierski, Michael E. Kopach, Christine A. Krumrich, Michael A. Staszak, Kevin A. Sullivan, Uko Udodong, Jeffrey T. Vicenzi

12-PO-117	Hydrothermal Organic Reactions. A Novel Annulation Reaction of Anilines with Ketones	217
	Hiyoshizo Kotsuki, Barun K. Mehta, Kazumichi Yanagisawa, Motoo Shiro

12-PO-118	Total Synthesis of Hamacanthin A and B Through Transamidation	218
	Takashi Kouko, Kei Hiramatsu, Tomomi Kawasaki

12-PO-119	High-Pressure Diels-Alder Reaction of Thiophene	219
	Koji Kumamoto, Isao Fukada, Hiyoshizo Kotsuki

12-PO-120	Synthesis of Optically Active Organoantimony Compounds Bearing Oxazoline Group and Their Evaluation for Asymmetric Reaction as Chiral Ligands	220
	Jyoji Kurita, Yoshihito Kishi, Kentaro Yamaguchi, Shuji Yasuike

12-PO-142	First Total Synthesis of Naturally Occurring Acetylenic Spiroacetal Enol Ether Epoxide (AL-2)	242
	Naoki Miyakoshi, Shinji Kitagaki, Chisato Mukai

12-PO-143	Synthesis of Benzofurans by Efficient [3,3]-Sigmatropic Rearrangement	243
	Okiko Miyata, Norihiko Takeda, Takeaki Naito

12-PO-144	Synthetic Studies on (+)-Naththyridinomycin	244
	Kazuki Mori, Toshiyuki Kan, Tohru Fukuyama

12-PO-145	Studies Toward an Asymmetric Total Synthesis of Quinine	245
	Makoto Mori, Robert M. Williams

12-PO-146	Planar Chiral β-Diketones as Optical Resolution Reagent of Amines	246
	Yasuko Morie, Ken-ichi Iwamoto, Satoshi Fujii, Masayuki Sato

12-PO-147	Synthetic Study of Property-Changeable Functional Dyes	247
	Kana Moriyama, Hidemitsu Uno, Noboru Ono, Takayuki Ishikawa

12-PO-148	New Approach in Synthesis of Heterocycles - Rearrangements of 1,2,3-Thiadiazoles and 1,2,3-Triazoles	248
	Yury Yu. Morzherin, T.V. Glukhareva, L.V. Dyudya, T.A. Pospelova, V.A. Bakulev

12-PO-149	Reactivity of 3-Alkyl/Aryl-3-thiocyanato-1H,3H-quinoline-2,4-diones with Nucleophiles and with Sulfuric Acid	249
	Antonín Klásek, Vladimír Mrkvička, Janez Košrnrlj

12-PO-150	The Interesting Reactivities of C₂-Indolic Acyl Group and Total Synthesis of Picrasidine V.	250
	Yasuoki Murakami, Hiroshi Yamada, Hideharu Suzuki

12-PO-151	Essential Structural Factors for the α-Glucosidase Inhibitory Activity of Salacinol; Role of the Substituents on the Side Chain	251
	Osamu Muraoka, Kazuya Yoshikai, Toshie Minematu, Genzoh Tanabe, Tao Wang, Hisashi Matsuda, Masayuki Yoshikawa

12-PO-152	Indium-Mediated Addition Reactions in Heterocycles	252
	Takeaki Naito, Hideto Miyabe, Masafumi Ueda, Azusa Nishimura

12-PO-153	Synthesis of Arunoamine B	253
	Shinsuki Nakahara, Akinori Kubo

12-PO-154	Synthesis of Liposidomycin: 1,4-Diazepane-3-one Ring Synthesis and Stereochemistry Assignment	254
	Noriyuki Nakajima, Takahiro Isobe, Shiro lrisa, Shouhei Fukunishi, Makoto Ubukata

12-PO-155	Synthesis and Evaluation of 5'-[4-(1-Substituted pyridinio)]-2-(5,2'-bithienyl)-carbaldehyde Iodide as a Fluorescent Labeling Reagent for HPCE	255
	Riichiro Nakajima, Norikatsu Aoyama, Yuki Matsui, Keiichi Noda, Takashi Tamura, Kazuhiko Tsukagoshi

12-PO-156	Aerobic Oxidative Aromatization of 1,3,5-Trisubstituted Pyrazolines and Hantzsch 1,4-Dihydropyridines Catalyzed by Pd/C	256
	Natsuki Nakamichi, Yuka Kawashita, Hirotoshi Kawabata, Masahiko Hayashi

12-PO-157	Design, Synthesis, and Biological Evaluation of Aminoboronic Acids as Growth Factor Receptor Inhibitors for EGFR, Flt-1 Tyrosine Kinases	257
	Hiroyuki Nakamura, Toru Asano, Yoshinori Yamamoto, Yoshimasa Uehara

12-PO-158	A Novel and Efficient Chiral Palladium-Phosphinooxazolidine Catalyst for the Enantioselective Diels-Alder Reaction	258
	Hiroto Nakano, Yuko Okuyama, Yuichiro Suzuki, Reiko Fujita, Chizuko Kabuto

12-PO-159	Catalytic Asymmetric Epoxidation of Olefins by C₂-Symmetric Chiral Dioxiranes	259
	Kumi Nakata, Madoka Kawamura, Ryuichi Shirai

12-PO-160	An Oxidative Intramolecular Non-Phenolic Coupling Reaction for the Synthesis of Spirodienone-Type Alkaloids Using a Combination of Hypervalent Iodine Reagent and Heteropoly Acid	260
	Hiromi Hamamoto, Yukiko Shiozaki, Hisanori Nambu, Hirofumi Tohma, Yasuyuki Kita

12-PO-161	*Synthesis of Thieno-1 ,2,4-Thiadiazine 1,1-Dioxides via* Intramolecular Copper Promoted Condensation of o-Halothienylsulfonyl Guanidines, Amidines or Isothioureas**	261
	Flemming E. Nielsen, Søren Ebdrup, Hanne T. Kornø, Claus U. Jessen, Per O.G. Arkhammar, John Bondo Hansen

12-PO-162	Nitroisoxazolone: Diverse Synthetic Intermediate for Polyfunctionalized Systems	262
	Nagatoshi Nishiwaki, Mina Tamura, Kazushige Hori, Yasuo Tohda, Masahiro Ariga

12-PO-163	Synthetic Study of Indoloiminoquinone Alkaloid Veiutamine	263
	Junko Nobuhiro, Maho Hirayama, Shigeo Tohyama, Tominari Choshi, Satoshi Hibino

12-PO-164	Synthesis of Antimalarial Yingzhaosu A Analogues by the Peroxidation of Dienes with CO(II)/O₂/Et₂SiH	264
	Takahiro Tokuyasu, Shigeki Kunikawa, Manabu Abe, Araki Masuyama, Masatomo Nojima, Hye-Sook Kim, Yusuki Wataya

12-PO-165	Synthesis of 2-Azacyclopentadienone by Ring Transformation of Squaric Acid and Its Conversion to Some Nitrogen Heterocycles	265
	Masatomi Ohno

12-PO-166	Reaction of 2-Phenyloxazolo[4,5-d]pyridazines with Nucleophiles	266
	Etsuo Oishi, Chitose Sugiyama, Ken-ichi Iwamoto

12-PO-167	*Synthesis of cis-* and trans-1 ,3,4-Selenadiazolines from Ketone Hydraxones**	267
	Kentaro Okuma, Kento Kubo, Kosei Shioji

12-PO-168	Novel, Efficient Chiral Sulfideoxathiane Ligands for Palladium-Catalyzed Asymmetric Allylic Alkylation	268
	Yuko Okuyama, Hiroto Nakano, Kouichi Takahashi, Hiroshi Hongo, Chizuko Kabuto

12-PO-169	The Asymmetric Total Synthesis of Spirotryprostatin A	269
	Tomoyuki Onishi, Paul R. Sebahar, Robert M. Williams

12-PO-170	Asymmetric Synthesis of (-)-Nakadomarin A	270
	Koji Ono, Masako Nakagawa, Atsushi Nishida

12-PO-171	Imidazoanthraquinol-Type Fluorescent Host: Clathrate Formation and Solid Fluorescence Enhancement Behavior	271
	Yousuki Ooyama, Katsuhira Yoshida

12-PO-172	Pd-Catalyzed Aromatic Carbonylation, Amination using Pd(OAc)₂-Cu(OAc)₂ Catalytic Systems	272
	Kazuhiko Orito, Akiyoshi Horibata, Takatoshi Nakamura, Harumi Ushito, Hideo Nagasaki, Motoki Yuguchi, Rika Harada, Masao Tokuda

12-PO-173	Synthesis and Properties of Highly Fluorescent Materials Based on Tricyclic Benzo[1,2]b:4,3-b']dithiophene	273
	Hideji Osuga, Yoshifumi Nakatani, Kazuhiko Tanaka

12-PO-174	Oligo(octithienylene-diethynylene)s as Unprecedentely Long Conjugated Nanomolecules	274
	Kiyofumi Inouchi, Seiji Kobashi, Kazuo Takimiya, Yoshio Aso, Tetsuo Otsubo

12-PO-175	*Simple Method for Preparation of Isofagomine and Its Analogs via* 5-Hydroxy-3-piperidene**	275
	Hidekazu Ouchi, Yukiko Mihara, Hiroki Takahata

12-PO-176	Synthesis of Functionalised 2,5-Diaryl[1,3,4]oxadiazoles for Use as Electron Transport Materials	276
	Stephen Oyston, Martin R. Bryce

12-PO-177	Heterocyclic Rearrangements: An Expedient Route to the Synthesis of Fluorinated Heterocyclic Compounds	277
	Andrea Pace, Silvestre Buscemi, Ivana Pibiri, Nicolò Vivona

12-PO-178	Viologen-Alkene CT complex: A Comparison Between Solution and Intrazeolite Behavior	278
	Andrea Pace, Edward L. Clennan

12-PO-179	Intramolecular 1,3-Dipolar Cycloaddition of Unsaturated Nitrones Derived from Carbohydrates	279
	Petra Pádár, Miklós Hornyák, Péter Forgó, Zoltán Kele, Nicola M. Howarth, Lajos Kovács

12-PO-180	Regio- and Diastereoselective Deprotonation of L-Glutamine Diol Dicarbamates: Asymmetric Synthesis of Indolizidines and Quinolizidines	280
	Lars Padeken, Dieter Hoppe

12-PO-181	*Hypoxanthine vs. DNA Bases: an Ab Initio* Study**	281
	Gábor Paragi, Zoltán Timár, Róbert Rónyai, Botond Penke

12-PO-182	Theoretical and Experimental Studies of Nitropyridine 1-Oxides	282
	Cyril Párkányi, Omar R. Martinez, Marwan Dakkouri

12-PO-183	Natural Product Synthesis Using Cyclisations of Iodonium Ions	283
	Aideen Dunne, Enrica Pascarella, Mike Casey

12-PO-184	Isoindolo[2,1-c]benzo[1,2,4]triazine: A New Ring System with Potential Antitumor Activity	284
	Diana Patrizia, Annamaria Martorana, Paola Barraja, Antonino Lauria, Alessandra Montalbano, Anna Maria Almerico, Gaetano Dattolo, Girolamo Cirrincione

12-PO-185	A Non-Cryogenic Method for the Preparation of 2-(Indolyl) Borates, Silanes and Silanols	285
	Joseph F. Payack, Enrique Vazquez, Ian W. Davies

12-PO-186	Oxidative Dearylation of Dihydropyridines	286
	J. Guillermo Penieres C, Ofelia Vega V., Eduardo López M., Carmen Márquez A., Cecilio Álvarez T.

12-PO-187	Synthesis of 1H-Indole in Heterogeneous Medium	287
	J. Guillermo Penieres C, J. Manuel Aceves H., Lucia Álvarez G., Miguel A. Cosme M., Cecilio Álvarez T.

12-PO-188	Asymmetric Michael Addition Reactions with Chiral α,β-Unsaturated N-Acyloxazolidinones	288
	Lydia Pérez, Leticia Quintero, Ceeilia Anaya de Parrodi, Eusebio Juaristi

12-PO-189	Synthesis of 2-Chloromethyl-4-oxo-3,4-dihydroquinazoline-7-carboxylic Acid Methyl Ester	289
	Sergey V. Pirogov, Alexandre V. Ivachtchenko

12-PO-190	Dihydropyrimidinone NPY Y₁ Receptor Antagonists	290
	Graham S. Poindexter, Mare A. Bruce, Graham Johnson, Lawrenee G. Iben, Rachel T. McGovern, Gail K. Mattson, Ildiko Antal-Zimanyi

12-PO-191	Design and Synthesis of Macrocyclic Inhibitors of the Hepatitis C NS3 Protease	291
	Martin Poirier, Murray Bailey, Dale R Cameron, Jean-Simon Duceppe, Jean-Marie Ferland, Elise Ghiro, Vida Gorys, Nathalie Goudreau, George Kukolj, Daniel Lamarre, Steven LaPlante, Montse Llinàs-Brunet, Mare-André Poupart, Jean Rancourt, Bruno Simoneau, Diane Thibeault, Herbert Nar, Youla S. Tsantrizos

12-PO-192	N-Alkyl-3,4-Thiophenedicarboximide, Monomers, Dimers and Polymers	292
	Martin Pomerantz, Ananda S. Amarasekara

12-PO-193	Alicyclic Isoxazolinone Antibacterial Agents	293
	Claude Quesnelle, Patrice Gill, Stephan Roy, Marco Dodier, Anne Marinier, Alain Martel, Lawrenee B. Snyder, Stanley D'Andrea, Joanne Bronson, MaryBeth Frosco, Danielle Beaulieu, Glen Warr, Ken Denbleyker, Terry Stickle, Hyekyung Yang, Susan Chaniewski, Cheryl Ferraro, Dennis Taylor, John Russell, Kenneth Santone, Junius Clarke, Rebecca L. Drain, Jay O. Knipe, Kathleen Mosure, John F. Barrett

12-PO-194	The Design of Ligands Based on Symmetrical and Unsymmetrical N-Alkyl Derivatives of 1,1'-Bis(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline)	294
	Benjamin Chan, Bing Deng, Michael Jones, Roger W. Read

12-PO-195	Synthesis and Ring Transformation of Some 1,3a,5,6,ωc-Pentaazaheterocycloalka[e]acenaphthylenes	295
	Gábor Berecz, József Reiter

12-PO-196	Unequivocal Synthesis of 6- and 7-Substituted Thiazolo[3,2-a]benzimidazoles	296
	Gordon W. Rewcastle, William A. Denny, Ellen M. Dobrusin, Daniel F. Ortwine

12-PO-197	Ligand Electronic Effects in Enantioselective Diethylzinc Additions	297
	Sandra M. Riordan, Mike Casey, Martin P. Smyth

12-PO-198	Electroorganic Synthesis of 1-Alkyl-2-methylbenzimidazoles	298
	Cynthia Torres, Luis A. Rivera, Carmen A. Vega

12-PO-199	Synthesis of Novel Macrocyclic Polyamine Complexes for Use as Anti-Cancer Prodrugs	299
	Laurie L. Parker, David J. Robins

12-PO-200	Synthetic Studies Towards Spirolaxine	300
	James E. Robinson, Margaret A. Brimble

5:30 - 6:30	Meeting of the International Society of Heterocyclic Chemistry (room to be announced)

August 13 (Wednesday)

9:00 - 12:20 Plenary Lectures (Main Ballroom, Lory Student Center, 2^nd Floor)

9:00	Chair: Professor Albert Padwa (Emory University, U.S.A.)
	*13-PL-7*
	Professor Andrew G. Myers Harvard University, USA
	Synthetic and Chemical Biological Studies of Saframycin A

10:00	Chair: Professor Tohru Fukuyama (University of Tokyo)
	*13-PL-8*
	Professor Yasufumi Ohfune Osaka City University, Japan
	Asymmetric Strecker Route Toward the Total Synthesis of Bioactive Natural Products

11 :00 - 11:20		BREAK

11:20	Chair: Professor Marco Ciufolini (Université Claude Bernard Lyon, France)
	*13-PL-9*
	Professor Erick M. Carreira ETH, Zurich, Switzerland
	Natural Products Inspired Studies in Asymmetric Synthesis

12:20		LUNCH

August 14 (Thursday)

9:00 - 12:30 Plenary Lectures (Main Ballroom, Lory Student Center, 2^nd Floor)

9:00	Chair: Professor Albert I. Meyers (Colorado State University)
	*14-PL-10*
	Professor Charles Rees Imperial College, UK
	Heterocyclic Chemistry: An Historical Perspective

10:00 - 10:10		Announcement of the forthcoming 20^th ICHC Professor Girolamo Cirrincione, University of Palermo, Italy

10:10	Award Ceremony: *Katritzky Junior Award in Heterocyclic Chemistry*
	Chair: Dr. Stanley Lang (Ribapharm, Inc., U.S.A.)
	*14-PL-11*
	Professor Peter Wipf University of Pittsburgh, USA
	1,3-Oxazoles and -Thiazoles in Natural Product Synthesis

11:10 - 11:30		BREAK

11:30	Award Ceremony: Pfizer Award in Hetrocyclic Chemistry
	Chair: Professor Robert M. Williams (Colorado State University, USA)
	*14-PL-12*
	Professor Tohru Fukuyama University of Tokyo, Japan
	Total Synthesis of Heterocyclic Natural Products-Highlights from Our Laboratories

12:30		LUNCH

2:00 - 2:40			Invited Lectures (Sections A, B, C, D)

Section A			(Room A-101 Clark) Chair: Professor Hans Neunhoffer (Darmstadt University of Technology)
*14-IL-25*
			Professor Tom Livinghouse, Montana State University, U.S.A.
			New Classes of Highly Active Non-Metallocene Group 3 Catalysts for Intramolecular Alkene Hydroamination, Pinacolborane Hydroboration and Hydrosilylation

Section B			(Room A-102 Clark) Chair: Professor Jetze Tepe (Michigan State University)
*14-IL-26*			Dr. Joel Hawkins, Pfizer CentraI Research, U.S.A.
			Laboratory Automation for Process R&D

Section C			(Room A-103 Clark) Chair: Professor Alan J. Kennan, Colorado State University
*14-IL-27*			Professor Peter Seeberger, Massachusetts Institute of Technology, U.S.A.
			Automated Solid Phase Synthesis of Blood Group Determinants and Cancer Vaccines

Section D			(Room A-104 Clark) Chair: Professor Tarek Sammakia (University of Colorado)
*14-IL-28*			Professor David Gin, University of Illinois Urbana, U.S.A.
			Exploring Strategies for Carbohydrate and Alkaloid Synthesis via O- and N-Heterocycles

2:40 - 3:00			Short Oral Sessions (Sections A, B, C, D)

Section A			(Room A-101 Clark) Chair: Professor Hans Neunhoffer (Darmstadt University of Technology)
*14-OR-17*
			An Approach to Total Synthesis of the Marine Ascidian Metabolite Perophoramidine via a Halogen-Selective Tandem Heck/Carbonylation Strategy
			G.D. Artman III, S.M. Weinreb (Pennsylvania State University)

Section B			(Room A-102 Clark) Chair: Professor Jetze Tepe (Michigan State University)
*14-OR-18*			Rivals for Oxazolines: Preparation and Applications of Imidazoline Ligands
			M. Casey (University College Dublin)

Section C			(Room A-103 Clark) Chair: Professor Alan J. Kennan, Colorado State University
*14-OR-19*			Synthesis and Binding Studies of Aminothiazoline-Carbohydrate Conjugates
			Ioannis Vrasidas, Rob M.J. Liskamp and Roland J. Pieters (Utrecht University)

Section D			(Room A-104 Clark) Chair: Professor Tarek Sammakia (University of Colorado)
*14-OR-20*			The (Absolute) Barrier to Enantiomerization of Unstabilized and Dipole-Stabilized 2-Lithiopyrrolidines
			N.J. Ashweek, P. Brandt, L Coldham, S. Dufour, F. Haeffner, R. Klein, R.E. Gawley (University of Arkansas)

3:00 - 3:30			BREAK

3:30 - 3:50			Short Oral Sessions (Sections A, B, C, D)

Section A			(Room A-101 Clark) Chair: Professar Hans Neunhoffer (Darrnstadt University of Technology)
*14-OR-21*
			Enantioselective Acylation of the meso-1,2,3-Triol Derivatives of myo-Inositol Catalyzed by CuCl₂-Chiral Diamine Complex: Improved Synthesis of Phosphatidylinositol 3,5-Bisphosphate
			A. Hamaguchi, A. Nishikawa, Ryuichi Shirai (Nara Institute of Science & Technology)

Section B			(Room A-102 Clark) Chair: Professor Jetze Tepe (Michigan State University)
*14-OR-22*			Studies Toward the Total Synthesis of Solanoeclepin A
			B.T.B. Hue, J. Dijkink, F.S. Guziec Jr., J.H. van Maarseveen and H. Hiemstra (University of Amsterdam)

Section C			(Room A-103 Clark) Chair: Professor Alan J. Kennan, Colorado State University
*14-OR-23*			Minor Groove Binders Substituted by Lipophilic Groups
			C.J. Suckling, R.D. Waigh, A.I. Khalaf, J. Parkinson, I.S. Hunter (University of Strathclyde)

Section D			(Room A-104 Clark) Chair: Professor Tarek Sammakia (University of Colorado)
*14-OR-24*			A Practical Synthesis of (+)-Biotin from L-Cysteine
			M. Seki, T. Shimizu, S. Yoshida, M. Hatsuda, M. Kimura, Y. Mori, S.Yamada (Tanabe Seiyaku Co.)

3:50 - 4:30			Invited Lectures (Sections A, B, C, D)

Section A			(Room A-101 Clark) Chair: Professor Hans Neunhoffer (Darmstadt University of Technology)
*14-IL-29*
			Professor Scott Miller, Boston College, U.S.A.
			Asymmetric Catalysis with Peptide-Based Heterocycles

Section B			(Room A-102 Clark) Chair: Professor Jetze Tepe (Michigan State University)
*14-IL-30*			Dr. John Macor, Bristol-Myers Squibb Company, U.S.A.
			Heteroarylsulfonamido Biphenyls as Potent Dual Antagonists Blocking Angiotensin and Endothelin Receptors and Useful as Novel Anti-Hypertensives

Section C			(Room A-103 Clark) Chair: Professor Alan J. Kennan, Colorado State University
*14-IL-31*			Profesor Itaru Hamachi, Kyushu University, Japan
			Protein/Peptide Recognition and Reaction by Artificial Receptors

Section D			(Room A-104 Clark) Chair: Professor Tarek Sammakia (University of Colorado)
*14-IL-32*			Dr. John Josey, Array BioPharma, Inc., U.S.A.
			Efficient, Stereospecific Synthesis of Oxazolo[3,2-a]pyrazin-5-ones: Novel Constrained Peptide Scaffolds from the Bicyclocondensation of 3-Aza-1,5-Ketoacids and Amino Alcohols

4:30 - 5:10			Invited Lectures (Sections A, B, C, D)

Section A			(Room A-101 Clark) Chair: Professor Hans Neunhoffer (Darmstadt University of Technology)
*14-IL-33*
			Professor Dieter Enders, Rheinisch-Westfälische Technische Hochschule, Germany
			Heterocycles as Auxiliaries, Catalysts and Synthetic Goals in Asymmetric Synthesis

Section B			(Room A-102 Clark) Chair: Professor Jetze Tepe (Michigan State University)
*14-IL-34*			Dr. Margaret M. Faul, Eli Lilly and Company, U.S.A.
			Synthesis and biological Activity of Novel Indolocarbazoles

Section C			(Room A-103 Clark) Chair: Professor Alan J. Kennan, Colorado State University
*14-IL-35*			Dr. Yagesh Sanghvi, ISIS Pharmaceuticals, U.S.A.
			Design and Synthesis of a new Silicon-Based Protecting Group and its Application in Nucleoside Chemistry

Section D			(Room A-104 Clark) Chair: Professor Tarek Sammakia (University of Colorado)
*14-IL-36*			Professor Randall L. Halcomb, University of Colorado, U.S.A.
			Synthesis of Bicyclic Ketals: Spiroketal-Based Glycopeptide Mimetics and the Bridged Bicyclic Ketal of Zaragozic Acid

5:10 - 6:30	POSTER SESSION III

14-PO-201	The Synthesis of Structurally Novel Bridged Glycosidic Fluoroindolocarbazoles as Topoisomerase I Inhibitors	301
	Edward Ruediger, Byron Long, Carol Bachand, Francis Beaulieu, Karen Bedingfield, Jeffrey Eummer, Craig Fairchild, David Frennesson, Mikael Mahler, Alain Martel, Mark Saulnier, Denis St. Laurent, Dolatrai Vyas, Kurt Zimmerman, Balu Balasubramanian

14-PO-202	Isolation and Characterization of Enticing Antitumor Isoquinoline Marine Natural Products from Pretreated with Potassium Cyanide with Thai Marine Organisms	302
	Naoki Saito, Yu-ichi Koizumi, Chieko Tanaka, Akinori Kubo, Khanit Suwanborirux, Surattana Amnuoypol, Kornvika Charupant

14-PO-203	*A Convenient Transformation of Carboxcylic Acids to Esters Using 1-tert-Butoxy-2-tert-Butoxycarbonyl-1,2-Dihydroisoquinoline (BBDI)*	303
	Yukako Saito, Hidekazu Duchi, Hiroki Takahata

14-PO-204	Syntheses of Azoloquinolines and Quinobenzodiazepines	304
	Alexander V. Ivachtchenko, Yuriy B. Sandulenko, Caroline Williams

14-PO-205	Asymmetric Deprotonation-Substitution of Chiral 1,3-Hexahidroimidazolidines	305
	Ericka Santacruz, Leticia Quintero, Cecilia Anaya de Parrodi, Eusebio Juaristi

14-PO-206	Syntheses of Thiopyrone and Pyrone Derivatives by Photocyclization Reaction of 3-Aryl-2-([1]benzothien-3-yl)propenoic Acids	306
	Kenji Sasaki, Yasuyoshi Satoh, Daiki Morisaki, Hiroki Kakuta, Takashi Hirota, Yoshinori Tominaga, Raymond N. Castle

14-PO-207	Highly Efficient Synthesis of Heterophanes by Intramolecular [2+2] Cycloaddition of Bis(acylketene)	307
	Masayuyki Sato, Tsunehisa Oda, Ken-ichi Iwamoto, Yumiko Suzuki, Kiyoshi Ikeda

14-PO-208	Synthesis of Cell-Permeable Caged Fluorescein Diphosphates as Photoactivatable Substrates for Protein Tyrosine Phosphatases	308
	Qingping Wang, John Scheigetz, Bruno Roy, Chidambaram Ramachandran, Michael J. Gresser

14-PO-209	Recent Progress on Halogen-Dance Reactions on Thiazoles	309
	Michael Schnürch, Peter Stanetty

14-PO-210	Synthetic Study of 1,10-Phenanthroline Derivatives with B-Ring Chirality	310
	Elke Schoffers, San Duc Tran, EunJoo Kim, Sun Wallace

14-PO-211	Nitrile Hydrolyzing Enzymes in the Synthesis of Enantiopure Functionalized Nitrogen Heterocycles	311
	C.A. Schortinghuis, J.K.S. Vink, H.E. Schoemaker, F.L. van Delft, F.P.J-T. Rutjes

14-PO-212	*Synthesis of Heterocyclic Compounds Containing Selenium and Nitrogen Atoms via* Cycloaddition Reaction of Selenoaldehydes**	312
	Masahito Segi, Aojia Zhou, Masumi Kojima, Katsuhiko Tanno, Yuki Endo, Mitsunori Honda

14-PO-213	Synthesis and Herbicidal Activity of Novel Substituted 2-Heteroaryl-5-methyl-4-phenoxypyrimidines	313
	Thomas P. Selby, Gerard M. Koether

14-PO-214	Synthesis and Cytotoxic Activity of Bis-Heterocycles Analogs to Bengazoles	314
	Laura Scarone, Diver Sellanes, Eduardo Manta, Gloria Serra, Peter Wipf

14-PO-215	*Conversion of 6H-1,3,5-Oxathiazine S-Oxides into 5H-1,2,4-oxathiazoles via* Novel Generation of 1,3-Thiaza-1,3-butadiene S-Oxides**	315
	Kazuaki Shimada, Islam Md. Rafiqul, Shigenobu Aoyagi, Yuji Takikawa

14-PO-216	Synthesis of Reveromycin A Derivatives and Its Biological Activities	316
	Takeshi Shimizu, Takeo Usui, Kiyotaka Machida, Kouichi Furuya, Hiroyuki Osada, Tadashi Nakata

14-PO-217	Synthetic Studies on Batzelladines	317
	Jun Shimokawa, Yuichi Hashimoto, Tadashi Nakata, Kazuo Nagasawa

14-PO-218	The Molecular Nature of Carbohydrate-Carbohydrate Interactions	318
	Graham L. Simpson, Barry Hayter, Timothy Gallagher

14-PO-219	Substitution Reactions of 5-Nitropyridine-2-Sulfonic Acid and Its Potassium Salt: A New Pathway to 2,5-Substituted Pyridines	319
	Jan M. Bakke, Ingrid Sletvold

14-PO-220	Rearrangements and Ring Contractions of Heteroaryldiazonium Salts and Azides	320
	Simon Rečnik, Jurij Svete, Branko Stanovnik

14-PO-221	Stereoselective Intramolecular Cyclization of Nitrogen-Substituted Stannylated Alkyl Carbamates	321
	Christian Stratmann, Dieter Hoppe

14-PO-222	Solid Phase Syntheses of Pteridines and Related Compounds	322
	Colin J. Suckling, Colin L. Gibson, Salvatore La Rosa, Judith Huggan, Sophie Oppillart

14-PO-223	Metalloporphyrin Catalyzed Regioselective Rearrangement of α-β-EpoxyKetones into 1,2-Diketones	323
	Kohji Suda, Kenji Baba, Shin-ichiro Nakajima, Toshikatsu Takanami

14-PO-224	Studies Towards the Total Synthesis of the Chartellines	324
	Cuixiang Sun, Xichen Lin, Steven M. Weinreb

14-PO-225	Asymmetric Synthesis of the Cyclopentane Core of Palau'amine	325
	Kosuki Namba, Uta Sundermeier, Robert M. Williams

14-PO-226	Synthesis of Heterophanes by Intramolecular [4+2] Cycloaddition of Bis(acylketene)	326
	Kie Suwa, Yumiko Suzuki, Kiyoshi Ikeda, Masayuki Sato

14-PO-227	Imidazolidenyl Carbene-Catalyzed Nucleophilic Acylation as a Tool for the Synthesis of Heterocyclic Compounds	327
	Yumiko Suzuki, Tomonori Toyota, Fumie Imada, Akira Miyashita, Masayuki Sato

14-PO-228	Origin for the Thiocrown Ether Mediated Modification of Lipase Reactivity	328
	Toshiyuki Itoh, Yumiko Takagi, Hiroshi Tsukube, Syun-suke Izumi, Toshifumi Hirata

14-PO-229	Catalytic Direct Introduction of Amino and Amido Nitrogen onto meso-Carbon of Porphyrins	329
	Toshikatsu Takanami, Mikiko Hayashi, Kohji Suda

14-PO-230	A Determination of the Absolute Stereochemistry of (-)-Linderol A	330
	Masayuki Yamashita, Takashi Shimizu, Ikuko Takao, Nobukazu Ohta, Ikuo Kawasaki, Shunsaku Ohta

14-PO-231	Novel Antimalarial Agents Targeting Parasitic Organelle: Antimalarial Activity of p-Delocalized Lipophilic Cations	331
	Kiyosei Takasu, Hiroki Terauchi, Tsubasa Shimogama, Hiroshi Inoue, Masataka Ihara

14-PO-232	Chirality Transfer from Epoxide to Carbanion: Alkylation of Metalated O-Protected Cyanohydrins of β-Silyl-α,β-epoxyaldehydes	332
	Kei Takeda, Eiji Kawanishi, Michiko Sasaki

14-PO-233	A Novel Synthesis of Pyrroloquinoline Core of the Martinellines via Radical Addition-Cyclization	333
	Yoshifumi Takeda, Toshiki Nakabayashi, Atsushi Shirai, Miki Hanaura, Takeaki Naito

14-PO-234	Enantio- and Diastereoselective Ir-Catalyzed Allylic Substitutions for Asymmetric Synthesis of β-Substituted α-Amino Acid Derivatives	334
	Takatoshi Kanayama, Kazumasa Yoshida, Hideto Miyabe, Yoshiji Takemoto

14-PO-235	Novel Synthesis of Isotellurazoles and Their Conversion into Pyridine Derivatives	335
	Yuji Takikawa, Akiko Morooka, Akiko Maruyama, Hisashi Kogawa, Yoriko Fujisawa, Shigenobu Aoyagi, Kazuaki Shimada

14-PO-236	Novel Nitrone-Formation Reaction and Its Application to Pyrrolidine and Pyrrolizidine Alkaloids	336
	Osamu Tamura, Atsushi Toyao, Hiroko Takagi, Hiroyuki Ishibashi

14-PO-237	An Interesting Intramolecular Cyclization of N-(2-Chloroethyl) Ureas	337
	Lushi Tan, Kenneth M. Wells, Peter G. Dormer, Nobuyoshi Yasuda

14-PO-238	Synthesis and Application of Novel, Axially Chiral 1,8-Disubstituted Naphthalenes	338
	Seiji Yoshikawa, Junichi Odaira, Ashutosh V. Bedekar, Takumi Furuta, Kiyoshi Tanaka

14-PO-239	Synthesis of Conformationally Restricted Analogues of Emivirine with Potential Activity Against HIV-1	339
	Frans D. Therkelsen, Erik B. Pedersen, Claus Nielsen

14-PO-240	*Ab Initio* Calculations on Simple Heterocycles and DNA Base-Pair Triplets	340
	Gábor Paragi, Zoltán Timár, Botond Penke

14-PO-241	Synthesis of a New Porphyrin-Phthalocyanine Dimer	341
	João P.C. Tomé, Cristina M.A. Alonso, Ana M.V.M. Pereira, Maria G.P.M.S. Neves, Augusto C. Tomé, Artur M.S. Silva, José A.S. Cavaleiro, Maria V. Martínez-Díaz, Tomás Torres

14-PO-242	Synthetic Studies on Salacinol Analogue with Sulfonium-Carboxylate Inner Salt	342
	Osamu Muraoka, Shunji Toya, Yoshiharu Matsuura, Toshie Minematu, Tomohisa Yasuhara, Genzoh Tanabe

14-PO-243	Synthetic Studies on Dart-Poison Frog Alkaloids 223A and 205B	343
	Naoki Toyooka, Ayako Fukutome, Hideo Nemoto, John W. Daly, Thomas F. Spande, H. Martin Garraffo, Tetsuo Kaneko

14-PO-244	Stereodivergent Process for the Synthesis of the Decahydroquinoline-Type Dendrobated Alkaloids	344
	Naoki Toyooka, Maiko Okumura, Hideo Nemoto

14-PO-245	Synthetic Studies Towards the Rubromycins	345
	Kit Yee Tsang, Margaret A. Brimble

14-PO-246	A Stereocontrolled Construction of 2-Azido-2-deoxy-β-glycosidic Linkages Capitalizing on 2-Azido-2-deoxyglycopyranosyl Diphenyl Phosphates	346
	Toshifumi Tsuda, Seiichi Nakamura, Shunichi Hashimoto

14-PO-247	Lipase-Catalyzed Enantioselective Desymmetrization of Prochiral 3,3-Bis(hydroxymethyl)oxindoles	347
	Shuji Akai, Toshiaki Tsujino, Emi Akiyama, Kouichi Tanimoto, Yasuyuki Kita

14-PO-248	o-Alkynylsydnones as Versatile Intermediates for Heterocyclic Synthesis	348
	Kenneth Turnbull, Andrew J. Weisner

14-PO-249	Novel Intermolecular Carbon Radical Addition to Cyclic Nitrone: The Asymmetric Synthesis of a-Amino Acids	349
	Masafumi Ueda, Hideto Miyabe, Masako Teramachi, Okiko Miyata, Takeaki Naito

14-PO-250	Catalytic Asymmetric 1,3-Dipolar Cycloaddition Reactions Utilizing Tartaric Acid Ester as a Chiral Auxiliary	350
	Yutaka Ukaji, Katsuhiko Inomata

14-PO-251	Hexagonal Columnar Porphyrin Structure by Unique Trimeric Assembly of a Porphyrin Dimer with π-π Stacking	351
	Hidemitsu Uno, Akane Masumoto, Kazuyuki Tominaga, Noboru Ono

14-PO-252	Microwave-Promoted Hetero-Diels-Alder Reactions of 2(1H)-Pyrazinones in Ionic Liquid Doped Solvents and on Solid Support	352
	Erik Van der Eycken, Oliver Kappe

14-PO-253	Synthesis and Applications of Oxazoline-Based Ligands	353
	H.L. van Lingen, K.F.W. Hekking, F.L. van Delft, F.P.J.T. Ruljes

14-PO-254	An Efficient Synthesis of 3-Carbomethoxy Isoquinolines	354
	Alfredo Vazquez, Angel Guzman

14-PO-255	*Novel Reductive Amination of Nitriles: An Efficient Route to 5-Hydroxypiperidone-Derived N,N-Acetals*	355
	Mandy K.S. Vink, Christien A. Schortinghuis, Herfried Griengl, Henk Hiemstra, Hans E. Schoemaker, Floris P.J.T. Ruljes

14-PO-256	A New Methodology of Catalytic Asymmetric Intramolecular Hetero Diels-Alder Reaction for Construction of Fused Heterocycles with Methyl (E)-4-Methoxy-2-oxo-3-butenoate	356
	Eiji Wada, Hidetaka Koga, Tomoyuki Manabe

14-PO-257	Synthesis of the Marine Bisindolotropolone Caulersin	357
	Niklas Wahlström, Birgitta Stensland, Jan Bergman

14-PO-258	Diels-Alder Reaction of Nitroquinolones Acting as Dienophiles with Butadiene Derivatives	358
	Reiko Fujita, Toshiteru Yoshisuji, Hideaki Wakamatsu

14-PO-259	Process Development of a Novel Topoisomerase I Inhibitor	359
	Daniel J. Watson, Eric D. Dowdy, Jianji Wang, Miguel Rosingana, Wen-Sen Li

14-PO-260	Strategies Towards Heterocycles by [3+2]Cycloaddition Reactions with Polymer-Supported Cyclic Nitrones	360
	Frank Wierschem, Karola Ruck-Braun

14-PO-261	Preparation of Biimidazoline, Bisimidazoline Ligands for Asymmetric Catalysis	361
	Philippa Wilkes, Nicola Boland, Mike Casey

14-PO-262	Preparation of 4-Phenylamino-3-quinolinecarbonitriles Substituted at C-7 by Pyridines, Furans, Alkenes and Alkynes	362
	Biqi Wu, Nan Zhang, Fei Ye, Diane H. Boschelli, Dennis W. Powell

14-PO-263	Novel Synthetic Approaches to 1,4-Disbustituted Pyrido[4,3-b] indoles	363
	James H. Wynne, Samuel D. Jensen, Christopher T. Lloyd, Wayne M. Stalick, Arthur W. Snow

14-PO-264	The Characteristics of Dihydropyrazines Having DNA Strand-Breakage Activity	364
	Tadatoshi Yamaguchi, Shigeru Ito, Nobuhiro Kashige, Hajime Nomura, Shinji Takechi

14-PO-265	Lewis Acid-Mediated Regio- and Diastereo-Selective 1,3-Dipolar Cycloadditions of Nitrile Oxide	365
	Hidetoshi Yamamoto, Saori Hayashi, Tomoaki Yamauchi, Akira Mori, Masatoshi Nishina, Akiko Nishida, Michihiko Noguchi, Shuji Kanemasa

14-PO-266	Introduction of an Oxo-group in Phospholene Heterocycles	366
	MitsujiYamashita, Motoki Maeda, Lakonda Nagaprasada Rao, Valiuru Krishna Reddy, Buchammagari Haritha, Takashi Katsumata, Hirono Totsuka, Masaki Takahashi, Tatsuo Oshikawa

14-PO-267	Stereospecific Epoxidation of 2-Phospholene 1-Oxides: Novel Synthesis of 5-Substituted-2- and 3-Phospholene 1-Oxides	367
	Valiuru Kirshna Reddy, Buchammagari Haritha, Hirono Totsuka, Masaki Takahashi, Mitsuji Yamashita

14-PO-268	Enantioselective C-H Amidations Catalyzed by Chiral Dirhodium(II) Complexes	368
	Minoru Yamawaki, Hideyuki Tsutsui, Masahiro Anada, Shunichi Hashimoto

14-PO-269	A Highly Effective Preparation of an α_vβ₃ Integrin Antagonist Part II. Synthesis of the β-Alanine and Imidazolidone Parts	369
	C. Yang, M.S. Jensen, N. Yasuda, Y. Hsiao, K.M. Welis, J. Yao, N. Rivera, D.L. Hughes

14-PO-270	Synthesis of 3-Deazauridine Analogues with Potential Antitumor Activity	370
	Hong Yang, Karl Miranda, Matt A. Peterson, Morris J. Robins

14-PO-271	Synthesis of 4-Chloro-5H-1,2,3-dithiazole Azomethylene Derivatives	371
	V.N. Yarovenko, A.A. Eskov, I.V. Zavarzin, M.M. Krayushkin

14-PO-272	Paltadium-Catalyzed Synthesis of N-Arylpiperazines of Insecticidal Interest	372
	Walt Yeager, Syed Ali, Edward Barron, Dan Cohen, Ben Dugan, Christina Madsen-Duggan, Elizabeth Rowley, Dominic Suarez, George Theodoridis

14-PO-273	Asymmetric Synthesis of α- and β-Substituted β-Amino Acids	373
	Yoko Yuasa, Ken Takada, Tsutomu Yokomatsu, Shibuya Shiroshi

14-PO-274	Practical Syntheses of (S)-4-Hydroxytetrahydrofuran-2-one, (S)-3-Hydroxytetrahydrofuran and Their (R)-Enantiomers	374
	Yoshifumi Yuasa, Haruki Tsuruta

14-PO-275	Synthesis of Indole Trimers	375
	Larisa Yudina, Niklas Wahlström, Jan Bergman

14-PO-276	Synthesis of Various Heterocyclic Compounds on the Basis of Monothiooxamides and Thiohydrazides of Oxaminic Acids	376
	I.V. Zavarzin, V.N. Yarovenko, A.V. Shirokov, N.G. Smimova, M.M. Krayushkin

14-PO-277	Studies Toward the Asymmetric Total Synthesis of Mitomycin C	377
	Guiru Zhang, Robert M. Wiliiams

14-PO-278	Solid-Phase Paraltel Synthesis of 1-(4-Substituted-amino-cyclohexyl)-2-oxo-2, 3-dihydro-1H-benzoimidazoles	378
	Xiaoming Zhou, Qun Sun, Donald J. Kyle

14-PO-279	Synthesis and Characterization of Thermodynamicalty Unstable PAH Epi-Sulfides, Sulfoxides	379
	Uri Zolter

14-PO-280	Chemoselective Paltadium Catalyzed Reaction in Aqueous Media: Selectivity in the Reaction of Bromoaniline with Altylalcohol	380
	Yuusaku Yokoyama, Hidemasa Hikawa, Satoru Kaneko, Yasuoki Murakami

14-PO-281	2,6-Bis[3-N,N-dimethylamino-1-oxopropen-1-yl)pyridine as Building Blocks in Heterocyclic Synthesis: New Routes to 2,2';6',2" terpyridines and 2,6-Bis-[pyrazolyl, isoxazolyl, pyrimidinyl, diazipenyl, pyrazolo[5,1-a]pyrimidinyl and pyrazolo[4,3-d]pyridazinyl] pyridine Derivatives	381
	Abuzied A. Hassanien

14-PO-282	The Development of Selective Chemical Probes for Viral RNA Structure Recognition	382
	Paul J. Lunt, Elizabeth A.M. Francis, David J. Berrisford, Johanna M. Avis

14-PO-283	Stereospecific Construction of ~-Isopropenyl Alcohol Moiety at the C(2) and (3) of Kaltolide A and Pinnatin A Using [2,3] Wittig Rearrangement of Cyclic Furfuryl Ethers	383
	Masayoshi Tsubuki, Kazunori Takahashi, Toshio Honda

6:45 - 9:00	Congress Banquet

August 15 (Friday)

9:00 - 11:20 Plenary Lectures and Closing Ceremony (Main Ballroom, Lory Student Center, 2^nd Floor)
9:00	Chair: Professor Louis S. Hegedus (Colorado State University)
	*15-PL-13*
	Professor Antonio Echavarren University of Madrid, Spain
	Transition-metal-Catalyzed Reactions of Alkynes for the Synthesis and Transformation of Heterocycles

10:00	Chair: Professor Tom Livinghouse (Montana State University, U.S.A.)
	*15-PL-14*
	Professor Fred Wudl University of California, Los Angeles, USA
	The Pivotal Role of Heterocycles in Organic Materials

11:00 - 11:20		CLOSING CEREMONY