Scientific Programs

Plenary Lectures, Award Address, and Honorary Invited Lecture

Room A

August 22 (Mon) 9:00-11:15

PL-1	Chemistry of N-Oxides: Further Developments
9:00	P. Potier (ICSN, CNRS, France)	1
	Chairman H. Rapoport (M. Hamana)
PL-2	Development of Microbial Secondary Metabolites with Potential Usefulness
10:15	H. Umezawa (Inst. Microbial Chem., Japan)	2
	Chairman P. Potier (Y. Ban)

August 23 (Tue) 9:00-11:15

PL-3	New Approaches to the Synthesis of Carbohydrates
9:00	T. Mukaiyama (Univ. Tokyo, Japan)	3
	Chairman A. I. Meyers (Y. Tamura)
PL-4	Probing Receptors with Natural and Synthetic Alkaloids
10:15	A. Brossi (NIH, USA)	4
	Chairman E. Wenkert (M. Hori)

August 24 (Wed) 9:00-11:15

PL-5	Synthesis of Unusual Molecules by Flash Vacuum Pyrolysis of Heterocyclic Compounds
9:00	C. Wentrup (Univ. Marburg, W. Gerrnany)	5
	Chairman A. Neunhoffer (T. Sasaki)
PL-6	The Synthesis and Properties of Polycyclic Aromatic Thiophenes and Related Heterocycles Occurring in Coal-Derived Products (Award Address)
10:15	R. N. Castle (Univ. South Florida, USA)	6
	Chairman W. Pfleiderer (Y. Mizuno)

August 25 (Thu) 9:00-11:15

PL-7	New Directions in Heterocyclic Synthesis Using Metalated Amides
9:00	V. Snieckus (Univ. Waterloo, Canada)	7
	Chairman S. W. Schneller (N. Inamoto)
PL-8	Six-Membered Zwitterionic Malonyl heterocycles
10:15	T. Kappe (Univ. Graz, Austria)	8
	Chairman H. Junek (T. Kato)

August 26 (Fri) 9:00-12:30

PL-9	Chemical and Biological Reactions of Reduced Pterins
9:00	W. L. F. Armarego (Australian Nat. Univ., Australia)	9
	Chairman L. B. Townsend (F. Yoneda)
PL-10	Alkylation of N-Heterocycles via Their α-Amino Carbanion
10:15	A. I. Meyers (Colorado State Univ., USA)	10
	Chairman H. Wasserman (S. Sakai)
H. Inv	Some Recent Progress in Natural Product Chemistry
11:30	D. H. R. Barton and W. B. Motherweil (ICSN, CNRS, France)	11
	Chairman T. Kametani (H. Yamanaka)

Session Programs

August 22 (Mon) Room A

Symposium V. Heterocycles in Anticancer and Antiviral Research (1)

Chairman J. A. Montgomery (Y Hashimoto) 12:45-14:15

S. Inv-17 Synthesis and Ring A Conformations of New Anthracyclines (Special Invited Lecture)
12:45	S. Penco, F. Angelucci, M. Ballabio, G. Barchielli, A. Suarato, E. Vanotti, A. Vigevani, and F. Arcamone (Farmitalia, Ricerca Chimica, Italy)	13
S-V-1	Condensed Pyrazoles. Synthesis of Pyrazolo[3,4-d]pyrimidin-4-ones and Pyrazolo[3,4-b] quinolin-4-amines
13:15	E.B. Pedersen, S.V. Nielsen, and P. Finlander (Odense Univ., Denmark)	14
S-V-2	A Synthetic Method for Pyrrolo[1,4]benzodiazepine Antitumor Antibiotics
13:30	T. Kaneko, H. Wong, and T.W. Doyle (Bristol-Myers Co., Ltd., USA)	15
S-V-3	1,3-Dienamines Reacting as 1,5-Dipoles in the Synthesis of N-Heterocycles
13:45	D.N. Reinhoudt, G.W. Visser, and W. Verboom (Twente Univ. Tech., Netherlands)	16
S-V-4	Antitumor Activity of Acodazole and Related Anilinoimidazo[4,5-f]quinolines
14:00	F.F. Ebetino (Norwich Eaton Pharm., Inc., USA)	17

Chairman F. F. Ebetino (N. Katagiri) 14:45-16:15

S-V-5	Interaction of 2-Aminodipyrido[1,2-a:3',2',d]imidazole with DNA. I. Structure of the Modified Nucleic Acid Base and Initial Chemical Event Caused by the Mutagen
14:45	Y. Hashimoto, K. Shudo, and T. Okamoto (Univ. Tokyo, Japan)			18
S-V-6	Interaction of 2-Aminodipyrido[1,2-a:3',2'-d]imidazole with DNA. I. Synthesis of New Intercalative Analogs
15:00	C.-S. Lee, T. Ohta, Y. Hashimoto, K. Shudo, and T. Okamoto (Univ. Tokyo, Japan)			19
S-V-7	Synthesis of Dihydro Diols as Potential Proximate Carcinogens of Benzo[c]acridines
15:15	J.K. Ray, G.K. Kar, and B.G. Chatterjee (Indian Inst. Tech., India)			20
S-V-8	Bond Alternation and Mutagenicity of Azulenoquinolines and Diazulenopyridines
15:30	T. Morita, Y. Takizawa, S. Okita, K. Takase, A. Tajiri, K. Wakabayashi, and T. Sugimura (Tohoku Univ. and Nat. Cancer Center Res. Inst., Japan)			21
S. Inv-18			Novel Ring Transformation Reactions and Their Application to the Syntheses of Potential Anticancer Heterocyclic Compounds (Special Invited Lecture)
15:45		K. A. Watanabe and T.-L. Su (Sloan-Kettering Inst., USA)		22

Chairman K. A. Watanabe (K. Senga) 16:30-18:00

S-V-9	Synthesis of Potential Anti-Cancer Agents
16:30	N.N. Singh, B. Singh, G.P. Singh, and P.N. Singh (Patna Univ., India)		23
S-V-10	Synthesis and Antitumor Activity of N¹-(4-Fluorobenzoyl)-3,5-diphenyl-4-sulfamoyl-phenylazo)-1,2-diazoles
16:45	C.P. Singh and Km. A. Chauhan (Sahu Jain Coll., India)		24
S-V-11	Design, Synthesis, and Potent Chemotherapeutic Activity of Certain Azole Nucleosides
17:00	P.C. Srivastava, S.G. Harris, G.R. Revankar, and R.K. Robins (Brigham Young Univ., USA)		25
S-V-12	Computer-Assisted Structure Antiturnor Activity Analysis of Purines, Purine Nucleosides and Their Aza and Deaza Analogs
17.15	M. Nasr, K.D. Paull, and V.L. Narayanan (Starks C.P., Inc. and NIH, USA)		26
S. Inv-19		Purines, Pyrimidines, Pteridines, and Cancer (Special Invited Lecture)
17:30	J.A. Montgomery (Southern Res. Inst., USA)		27

August 22 (Mon) Room B

Symposium III. Synthesis of Natural Heterocycles (1)

Chairman W N. Speckarnp (C. Kaneko) 12:45-14:15

S-III-1	Heterocyclic Systems via Functionally Substituted Vinyl Carbanions
12:45	R.R. Schmidt, R. Betz, O. Miyata, and J. Kast (Univ. Konstanz, W. Germany)		28
S-III-2	Studies in the Synthesis of Lorostemin and Related Pyranoxanthones
13:00	C.S. Rukmani Iyer and P.R. Iyer (Indian Inst. Tech. Bombay, India)		29
S. Inv-9		Synthesis of Bioactive Natural Heterocycles with Polyfunctional Groups (Special Invited Lecture)
13:15	T. Goto and S. Nakatsuka (Nagoya Univ., Japan)		30
S-III-3	Alkaloid Synthesis through Electron Transfer Mediated Cyclisation of o-Halogenated N-Acylbenzylamines
13:45	S.V. Kessar, P. Singh, R. Kaur, and P. Singla (Panjab Univ., India)		31
S-III-4	Synthetic Approach toward Naphthyridinomycin
14:00	T. Fukuyama, R.K. Frank, A.A. Laird, and G.A. Krudy (Rice Univ., USA)		32

Chairman A. S. Kende (S. Nakatsuka) 14:45-16:15

S. Inv-10		Heterocyclic Diels-Alder Reactions for the Synthesis of Natural Products (Special Invited Lecture)
14:45	S. M. Weinreb (Pennsylvania State Univ., USA)		33
S-III-5	Synthesis of Nitrogen-containing Polycycles Based upon New Generation of o-Quinone Methide Imine
15:15	Y. Ito, E. Nakajo, M. Nakatsuka, and T. Saegusa (Kyoto Univ., Japan)		34
S-III-6	Synthesis of (±)-Lasubine-I and (±)-Subcosine-II
15:30	H. Iida, M. Tanaka, and C. Kibayashi (Tokyo Coll. Pharm., Japan)		35
S-III-7	Synthetic Studies on Necine Bases of Pyrrolizidine Alkaloids
15:45	H. Niwa, A. Kuroda, Y. Uosaki, and K. Yamada (Nagoya Univ., Japan)		36
S-III-8	A Novel Cyclization for the Synthesis of Nitrogen-containing Heterocycles: The Synthesis of (±)-Heliotridane, (±)-Nuphar Indolizidine, and (±)-Dihydrodeoxyotonecine
16:00	T. Ohnuma, K. Shiiya, M. Tabe, M. Nagasaki, and Y. Ban (Hokkaido Univ., Japan)		37

Chairman S. M. Weinreb (C. Kibayashi) 16:30-18:00

S-III-9	A Stereoselective Synthesis of the Compound Having Palustrine Structure
16:30	M. Ogawa, I. Yoda, M. Natsume, and M. Shiro (Itsuu Lab. and Shionogi & Co., Ltd., Japan)	38
S-III-10	Synthesis of Quinazolinocarboline Alkaloids
16:45	J. Bergman (Royal Inst. Tech., Sweden)	39
S. Inv-11	New Tactics in Heterocyclic Synthesis (Special Invited Lecture)
17:00	A.S. Kende (Univ. Rochester, USA)	40
S-III-11	Alkaloid Syntheses Using Photochemical Reactions
17:30	C. Kaneko, T. Naito, C. Miwa, and T. Ohashi (Kanazawa Univ., Japan)	41
S-III-12	Total Synthesis of (+)- and (-)- Tryptoquivaline G and L by Biomimetic Double Cyclization
17:45	M. Nakagawa, M. Taniguchi, M. Sodeoka, M. Ito, K. Yamaguchi, and T. Hino (Chiba Univ., Japan)	42

August 22 (Mon) Room C

Symposium II. Heterocycles with Novel Functions (1)

Chairman D. N. Reinhoudt (E. Kimura) 12:45-15:30

S. Inv-5		Macropolycyclic Compounds as Host Molecules (Special Invited Lecture)
12:45	I. O. Sutherland (Univ. Liverpool, UK)		43
S-II-1	Crown Ethers of Low Symmetry. 14- to 17-Crown 5 and 17- to 22-Crown-6
13:15	M. Ouchi, Y. Inoue, and T. Hakushi (Himeji Inst. Tech., Japan)		44
S-II-2	Synergistic Solvent Extraction of Crown Ether Complexes with Alkali Metal Picrates by Neutral Donor Solvents
13:30	Y. Takeda (Chiba Univ., Japan)		45
S-II-3	Metal Ion Uptake and Release with 2,2'-Bipyridine Derivatives by pH Switching
13:45	S. Shiraishi, N. Kishii, and K. Araki (Univ. Tokyo, Japan)		46
S-II-4	Active Transport of Alkali Metal Cations Using Crown Ethers Having an Amino Group
14:00	Y. Nakatsuji and M. Okahara (Osaka Univ., Japan)		47
S-II-5	Thiol-bearing Crown Ethers as Enzyme Models for the Synthesis of Peptides
14:45	S. Sasaki, M. Shionoya, and K. Koga (Univ. Tokyo, Japan)		48
S-II-6	Is 3-Methyl[15]annulenone-Hydroxy-3-methyl[15]annulenylium Ion Cycle Mimic to Bacteriorhodopsin Cycle?
15:00	H. Ogawa, M. Kuribayashi, H. Morita, T. Imoto, I. Miyamoto, H. Kato, and Y. Taniguchi(Kyushu Univ. and Kurume Tech. Coll., Japan)		49
S-II-7	18<(2,6)Pyridino₆coronand-6>: "Sexipyridine"
15:15	G.R. Newkome and H.-W. Lee (Louisiana State Univ., USA)		50

Chairman G. R. Newkome (M. Hirobe) 15:30-17:30

S. Inv-6		Metal Porphyrin Complexes with Novel Functions (Special Invited Lecture)
15:30	Z. Yoshida (Kyoto Univ., Japan)		51
S-II-8	Asymmetric Charge Distribution in Metallochlorins
16:00	A. Ulman (Weizmann Inst. Sci., Israel)		52
S-II-9	Picket-gable Porphyrin as a New Hb Model
16:30	I. Tabushi, T. Sasaki, and T. Kondo (Kyoto Univ., Japan)		53
S-II-10	Electron-Deficient Porphyrins. 1. Perfluoroalkylporphyrins
16:45	H. Ogoshi, M. Homma, Y. Aoyama, and K. Aoyagi (Tech. Univ. Nagaoka, Japan)		54
S-Inv-7		Synthesis and Properties of Novel Porphyrins for Use as Oxygen-Reduction Catalysts (Special Invited Lecture)
17:00	T.G. Traylor, T.A. Evans, R. Hildreth, and K.B. Nolan (Univ. California-San Diego, USA)		55

August 22 (Mon) Room D

General Sessions (Oral) (G) (1)

Chairman A. Dondoni (Y. Nagao) 12:45-14:15

G-1	Heterocycles as Masked Functional Monomers
12:45	H. Ulrich, S.-H. Dai, and F.A. Stuber (Upjohn Co., USA)	56
G-2	Reactions of Vinimidinium Salts of Furan Derivatives
13:00	J. Kovác, T. Gracza, and Z. Arnold (Univ. Bratislava and Czech. Akad. Sci., Czechoslovakia)	57
G-3	A New Synthetic Method of b-Substituted Furans
13:15	K. Itoh and H. Nishiyama (Toyohashi Univ. Tech., Japan)	58
G-4	2-Cyanotetrahydrofurans via Cyano-oxyselenenylation
13:30	S. Tomoda, Y. Takeuchi, and Y. Nomura (Univ. Tokyo, Japan)	59
G-5	Cyclization of Some Heterocyclic Dialdehydes with Nitromethane
13:45	M.El Borai (Tanta Univ., Egypt)	60
G-6	The Claisen Rearrangement of Aryl Propargyl Ethers in Poly(ethylene glycol). An Improved Method for the Synthesis of (2H)Benzopyrans and 2-Methylbenzofurans
14:00	U. Rao and K.K. Balasubramanian (Indian Inst. Tech. Madras, India)	61

Chairman G. Bernath (Y. Takeuchi) 14:45-16:15

G-7	Indenoisocoumarins: Synthesis of Indenoisocoumarins
14:45	G. Jha and J.N. Srivastava (Bhagalpur Univ., India)	62
G-8	Synthesis and Reactions of Some 1,3-Oxazolium-4-olate
15:00	M.J. Haddadin and H. Tanous (American Univ. Beirut, Lebanon)	63
G-9	Autocatalyzed Additions and Cycloadditions of Ketenes to Thiazoles
15:15	A. Dondoni, G. Fantin, M. Fogagnolo, A. Medici, and P. Pedrini (Univ. Ferrara, Italy)	64
G-10	A New Nonenzymatic Chiral Induction into Cyclic meso-Compounds
15:30	Y. Nagao, T. Inoue, and E. Fujita (Kyoto Univ., Japan)	65
G-11	Facile One-pot Synthesis of Benzothiazolones from 2-Halonitrobenzenes
15:45	I. Nishiguchi, K. Konishi, and T. Hirashima (Osaka Municipal Tech. Res. Inst., Japan)	66
G-12	Syntheses of Thiazoles and Thiazines from Allenes
16:00	S.R. Landor, P.D. Landor, Z.T. Fomum, J.T. Mbafor, and J. Silike-Muruumu (Univ. West Indies, Jamaica)	67

Chairman A. K. S. Gupta (Y. Oshiro) 16:30-18:00

G-13	Lithiation of Five-membered Heteroaromatic Compounds. The 5-Alkoxymethyl- and 5-Alkylthiomethylisoxazoles
16:30	R.G. Micetich, C.C. Shaw, P. Spevak, and P. Wolfert (Univ. Alberta, Ayerst Lab., and Chembiomed Ltd., Canada)	68
G-14	A Synthesis of Geminally Functionalized Cyclic Aminocarboxylic Acids by Diels-Alder Reaction and 1,3-Dipolar Cycloaddition Using α,b-Dehydroalaninates
16:45	H. Horikawa, T. Nisbitani, T. Iwasaki, and I. Inoue (Tanabe Seiyaku Co., Ltd., Japan)	69
G-15	Newer Heterocycles from Fluorochalcones
17-00	N. Latif, N. Mishriky, and W. Basyouni (Nat. Res. Centre, Cairo, Egypt)	70
G-16	Ring Transformation Reaction of Heterocyclic Sulfoxides
17:15	N. Ueda, H. Shimizu, T. Kataoka, and M. Hori (Gifu Coll. Pharm., Japan)	71
G-17	Some Unexpected Oxidation Reactions of 1,3-Benzothiazines. A New Isoquinoline Synthesis by Ring Transformation of 1,3-Benzothiazinc-b-lactams
17:30	J. Szabó, L. Fodor, E. Szücs, G. Bernáth, and P. Sohár (Univ. Med. School Szeged and EGYT Pharm. Works, Hungary)	72
G-18	Studies on Phenothiazines, 4H[1,4]-Benzothiazines and Their Sulphones
17:45	R.R. Gupta, G.S. Kalwania, M. Kumar, and R. Kumar (Univ. Rajasthan, India)	73

August 22 (Mon) Room E

General Sessions (Oral) (G) (2)

Chairman M. S. R. Naidu (M. Takeda) 12:45-14:15

G-19	Transannular Interactions in the Reactions of Sulfilimines of Cyclic Polythiaethers with Strong Bases
12:45	N. Furukawa, K. Imaoka, A. Kawada, and S. Oae (Univ. Tsukuba, Japan)	74
G-20	Facile Reduction of Sulfoxides and Sulfilimines to Sulfides by Using Metal/Chloromethylsilanes
13:00	K. Nagasawa, T. Umezawa, and K. Itoh (Hokkaido Coll. Pharm., Japan)	75
G-21	New Mode of Thermal Reactions of Cyclic Sulfur Ylides. Solvent Uptake and Spiro-compound Formation
13:15	M. Kataoka, T. Kataoka, H. Shimizu, and M. Hori (Gifu Coll. Pharm., Japan)	76
G-22	Synthesis and Properties of Bridged Thionin
13:30	R. Okazaki, T. Hasegawa, Y. Shishido, and N. Inamoto (Univ. Tokyo, Japan)	77
G-23	Bridged Heteronins, Thiecinone, and Related Systems from Mesoionic Compounds
13:45	H. Kato, M. Hashimoto, and K. Ikoma (Shinshu Univ., Japan)	78
G-24	1,2-Dithiolylium Salts in the Synthesis of 1,2-Tetrathiafulvalenes
14:00	C. Th. Pedersen and O. Hammerich (Odense Univ. and Univ. Copenhagen, Denmark)	79

Chairman C. T. Pedersen (N. Furukawa) 14:45-16:15

G-25	1-Methyl-2-azathiabenzene 1-Oxide: Synthesis and Some Properties
14:45	M. Ikeda, Y. Tamura, H. Tsubouchi, and M. Tsunekawa (Kyoto Coll. Pharm. and Osaka Univ., Japan)	80
G-26	The Homothiopyrylium Ions
15:00	K. Yamamoto, S. Yamazaki, A, Matsukawa, and I. Murata (Osaka Univ., Japan)	81
G-27	New Purple Pigment Produced by Brevibacterium fluvum
15:15	C. Eguchi and Y. Yokokawa (Ajinomoto Co., Inc., Japan)	82
G-28	Synthesis and Structure of Novel Halosulfuranes, 5-Chloro- and 5-Bromo-5,11-dihydrodibenzo[b,e]thiepins
15:30	K. Onogi, M. Hori, T. Kataoka, H. Shirnizu, and M. Kido (Kowa Co., Ltd., Gifu Coll. Pharm., and Otsuka Pharm. Co., Ltd., Japan)	83
G-29	Synthesis of 2-Substituted imino-1,3-dithioles, 2-Substituted imino-1,3-thiaselenoles and 2-Substituted imino-1,3-diselenoles
15:45	A. Shafiee and G. Fanaii (Tehran Univ., Iran)	84
G-30	Novel Bicyclic σ-Selenuranes: Syntheses and Reactions of 9-Alkyl (or Aryl)-10-chloro-10,9-epoxyethanoselenoxanthenes and Their Related Compounds
16:00	K. Tomimatsu, T. Kataoka, H. Shimizu, and M. Hori (Gifu Coll. Pharm., Japan)	85

Chairman P. Tovivich (M. Ikeda) 16:30-17:30

G-31	Insecticidal Cyclic Phosphorus Compounds
16:30	S. Tawata and N. Kobamoto (Univ. Ryukyus, Japan)	86
G-32	Synthesis of 2,3-Dihydro-2-phenoxy-1H-1,3,2-benzodiazaphosphole 2-Sulphides
16:45	M.S.R. Naidu and R.L. Dannley (Sri Venkateswara Univ., India and Case Western Reserve Univ., USA)	87
G-33	Isolation and Characterization of a Thiadiphosphirane
17:00	M. Yoshifuji, K. Shibayama, K. Ando, and N. Inamoto (Univ. Tokyo, Japan)	88
G-34	New Developments for the Preparation of Allylic Monophosphates
17:15	M. Garrossian (Nat. Iranian Ind. Org., Iran)	89

August 22 (Mon) Room F

General Sessions (Oral) (G) (3)

Chairman H. Suschitzky (H. Ishii) 12:45-14:15

G-35	Advances in Reissert Compound Chemistry
12:45	F.D. Popp and J. Kant (Univ. Missouri-Kansas City, USA)	90
G-36	The Tetrahydroisoquinoline Oxidative Rearrangement
13:00	H. Hara, H. Shinoki, O. Hoshino; and B. Umezawa (Sci. Univ. Tokyo, Japan)	91
G-37	Mechanism of the Condensation Reaction between 1-Aryl- and Heteroaryl-1,4-dihydro3(2H)-isoquinolinones and Aldehydes
13:15	L. Hazai, Gy. Deák, J. Tamás, G. Doleschall, and G. Tóth (Hungarian Acad. Sci. and Tech. Univ. Budapest, Hungary)	92
G-38	A Synthetic Methodology for the Synthesis of Optically Active Heterocycles by Enamide Photocyclization
13:30	T. Naito, Y. Tada, and I. Ninomiya (Kobe Women's Coll. Pharm., Japan)	93
G-39	Syntheses of Despyrrole Analogs of Ergoline Group of Alkaloids
13:45	I. Ninomiya, T. Kiguchi, C. Hashimoto, and T. Naito (Kobe Women's Coll. Pharm., Japan)	94
G-40	Syntheses of Coumarinoxy Benzylisoquinolines
14:00	D. Ramesh and M. Srinivasan (Indian Inst. Tech. Madras, India)	95

Chairman F. D. Popp (I. Ninomiya) 14:45-16:15

G-41	Ring Transformations of 1-Aza-dibenzo[c,f]bicyclo[3.3.1]nona-3,6-dienes
14:45	H. Takayama, T. Nomoto and N. Nasui (Teikyo Univ., Japan)	96
G-42	Preparation of Nitrones from Secondary Amines. Tungstate Catalyzed Oxidation of Secondary Amines with Hydrogen Peroxide
15:00	S. Murahashi, H. Mitsui, and S. Zenki (Osaka Univ., Japan)	97
G-43	Acyliminium Salts: Synthesis and Properties
15:15	J. Dusemund and E. Kröger (Freie Univ. Berlin, W. Germany)	98
G-44	Photo-Ring Expansion of Azidomethoxyquinolines to Methoxypyridoazepines
15:30	R.K. Smalley, E.F.V. Scriven, and H. Suschitzky (Univ. Salford, UK)	99
G-45	Intramolecular Aminopalladation Reaction of 1-Aminohexatriene
15:45	H. Taniguchi, H. Yamasaki, N. Okada, K. Isomura, and S. Kobayashi (Kyushu Univ., Japan)	100
G-46	Reissert Type's Reaction by Use of Phosphite
16:00	Y. Hamada, I. Takeuchi, and Y. Shibata (Meijo Univ., Japan)	101

Chairman T. Fukuyama (H. Takayama) 16:30-17.30

G-47	Stereocontrolled Synthesis of Withaferin A and Withanolide D
16:30	K. Gamoh, M. Hirayama, and N. Ikekawa (Tokyo Inst. Tech., Japan)	102
G-48	Isolation and Structure of New Alkaloids from Buxus Papilosa
16:45	Atta-ur-Rahman, Mehrun Nisa, S. Farhi, and T.Z. Ismail (Univ. Karachi, Pakistan)	103
G-49	Novel 2'-Substituted Amino-3-methoxy-16α-bromo-17-oxoestra-1,3,5(10)-trieno[1,2-d]thiazoles
17:00	A.-M.M.E. Omar and O.M. Aboulwafa (Univ. Alexandria, Egypt)	104
G-50	Investigations Concerning the Total Synthesis of B-Nor-6,12-bisthiaestra-1,3,5(10),8,14- pentaen-17-one
17:15	S. R. Ramadas and J. Appa Rao (Indian Inst. Tech. Madras, India)	105

August 23 (Tue) Room A

Symposium IV. New b-Lactams and Other Heterocyclic Antibiotics (1)

Chairman B. G. Christensen (S. Kobayashi) 12:45-14:15

S. Inv-13	Advances in Stereochemical Control (Special Invited Lecture)
12:45	S. Masamune (MIT., USA)	107
S-IV-1	New Synthesis of 1,4-Benzodiazepine Derivatives via Palladium Catalyzed Carbonylation
13:15	M. Mori, M. Ishikura, M. Terashima, M. Kimura, and Y. Ban (Hokkaido Univ. and Higashi-Nippon-Gakuen Univ., Japan)	108
S-IV-2	A Synthetic Approach to the Mechanism of DNA-Cleavage by Bleomycin-Fe(II)-O₂ Complex
13:30	M. Otsuka, A. Kittaka, Y. Sugano, S. Kobayashi, Y. Sugiura, T. Takita, H. Umezawa, and M. Ohno (Univ. Tokyo, Kyoto Univ., and Inst. Microbial Chem., Japan)	109
S-IV-3	Synthesis of b-Lactam Antibiotics via the Sulfeno-cycloamination
13:45	M. Ihara, Y. Haga, M. Yonekura, K. Fukumoto, and T. Kametani (Tohoku Univ. and Hoshi Univ., Japan)	110
S-IV-4	7α-Hydroxycephaiosporin C, an Intermediate in the Methoxylation of Cephalosporin C by a Cell-Free Extract of S. Clavuligerus
14:00	J.D. Hood, A. Elson, M.L. Gilpin, and A.G. Brown (Beecham Pharm. Res. Div., UK)	111

Chairman W. A. Slusarchyk (I. Kawamoto) 14:45-16:15

S. Inv-14	Highly Stereoselective Synthesis of Antitumor Antibiotics, (+)-Actinobolin and Bactobolin, by Asymmetric Cyclization (Special Invited Lccture)
14:45	M. Yoshioka, H. Nakai, and M. Ohno (Univ. Tokyo, Japan)	112
S-IV-5	Syntheses of Althiomycin and Its Analogs in Relation to Their Antibacterial Activities
15:15	T. Shiba, K. Inami, and H. Imanaka (Osaka Univ., Japan)	113
S-IV-6	The Structure of Medermycin
15:30	H. Ogura and K. Furuhata (Kitasato Univ., Japan)	114
S-IV-7	Synthetic Study of Carbapenems Utilizing D-Glucosamine
15:45	N. Chida, M. Miyashita, and A. Yoshikoshi (Tohoku Univ., Japan)	115
S-IV-8	Synthesis of Some 1-Aza/Oxa-Analogs of Cepham
16:00	S.D. Sharma and U. Mehra (Panjab Univ., India)	116

August 23 (Tue) Room B

Symposium V. Heterocycles in Anticancer and Antiviral Research (2)

Chairman V. L. Narayanan (T. Shimidzu) 12:45-14:15

S-V-13	The Binding Sites in Xanthine and Methyl Substituted Xanthines with Some Group VIII Transition Metals
12:45	J.R. Lusty and J. Peeling (Nat. Univ. Singapore, Singapore and Univ. Petroleum Minerals, Saudi Arabia)	117
S-V-14	Circular Dichroism and Fluorescence Studies on the Interactions of Vincristine to Homopolyribonucleotides
13:00	H.N. Borazan and M.E. Zia (Univ. Baghdad, Iraq)	118
S-V-15	Chemical Synthesis and Biological Activity of 5'-"Capped" 2',5'-Oligoadenylates
13:15	J. Imai and P.F. Torrence (NIH, USA)	119
S-V-16	Synthesis and Biological Activity of a Tubercidin Analog of 2-5A
13:30	J.-C. Jamoulle, J. Imai, and P.F. Torrence (NIH, USA)	120
S. Inv-20	2'-Substituted 2'-Deoxypurinenucleotides - Their Conformation and Properties (Special Invited Lecture)
13:45	M. Ikehara (Osaka Univ., Japan)	121

Symposium III. Synthesis of Natural Heterocycles (2)

Chairman V. Snieckus (N. Aimi) 14:45-16:15

S-III-13	Total Synthesis of (±)-Clavicipitic Acid
14:45	S. Nakatsuka, T. Masuda, K. Yamada, and T. Goto (Nagoya Univ., Japan)	122
S-III-14	Synthesis of Active Fragments of Teleocidins and Lyngbyatoxins
15:00	Y. Endo, K. Shudo, and T. Okamoto (Univ. Tokyo, Japan)	123
S. Inv-12	Imines and Iminium Ions in Stereoselective Natural Product Synthesis (Special Invited Lecture)
15:15	W.N. Speckamp (Univ. Amsterdam, Netherlands)	124
S-III-15	A Synthetic Pathway to Strychnos, Aspidosperma, Schizozygane and Eburnamonine Alkaloids by Way of the Novel Photoisomerization
15:45	Y. Ban, K. Yoshida, S. Nomura, J. Goto, and T. Oishi (Hokkaido Univ., Japan)	125
S-III-16	Synthetic Approach toward Mitomycins. New Facile Synthesis of 3H-Pyrrolo [1,2-a]indol-5,8-diones
16:00	Y. Naruta, N. Nagai, and K. Maruyama (Kyoto Univ., Japan)	126

August 23 (Tue) Room C

Symposium II. Heterocycles with Novel Functions (2)

Chairman I. O. Sutherland (M. Okahara) 12:45-14:15

S-II-11	New Type of ipso-Substitution in Pyridine Ring and Its Application for the Synthesis of Macrocycles Containing Both Oxa- and Thia-bridges
12:45	N. Furukawa, T. Kawai, S. Ogawa, and S. Oae (Univ. Tsukuba, Japan)	127
S-II-12	The Preparation of Macrocyclic Polyether-Diester Ligands Containing the Pyridine Subcyclic Unit, Their Complexes and Their Reductive Desulfurization to the Pyridino-Crown Ethers
13:00	B.A. Jones, J.S. Bradshaw, P.R. Brown, R.B. Davidson, J.J. Christensen, and R.M. Izatt(Brigham Young Univ., USA)	128
S-II-13	Synthesis of Multifunctional Macrocyclic Polyamines from Natural Amino Acids
13:15	T. Yatsunami, E. Kimura, and M. Kodama (Hiroshima Univ., Japan)	129
S-II-14	Selection of Guest Inclusion Geometry by a Series of Water-soluble Paracyclophanes Having Well-defined Hydrophobic Cavities
13:30	K. Mori, K. Odashima, A. Itai, Y. Iitaka, and K. Koga (Univ. Tokyo, Japan)	130
S-II-15	Host-Guest Complex Formation by an Optically Active Paracyclophane in Water
13:45	I. Takahashi, K. Odashima, and K. Koga (Univ. Tokyo, Japan)	131
S-II-16	Lipophilic and Amphiphilic Cyclodextrin Derivatives as the New Class of Host Compounds
14:00	W. Tagaki, Y. Irinatsu, H. Takahashi, and S. Kozuka (Osaka City Univ., Japan)	132

Chairman J. S. Bradshaw (S. Shiraishi) 14:45-16:15

S-II-17	Flavin Catalysts Bearing Sulfur Functional Groups
14:45	K. Fujimori, T. Nagata, and S. Oae (Univ. Tsukuba, Japan)	133
S-II-18	Novel Function of the Pyrroloquinoline Quinone, PQQ, Enhanced by Micelle
15:00	Y. Ohshiro, T. Hirao, and T. Agawa (Osaka Univ., Japan)	134
S-Inv-8	Dyestuff Lasers and Light Collectors - Two New Fields of Application for Fluorescent Heterocyclic Compounds (Special Invited Lecture)
15:15	R. Raue, K.H. Drexhage, and H. Harnisch (Bayer AG and Univ. Siegen. W. Germany)	135
S-II-19	Syntheses of a New Class of Dyes - Coupling Reactions of Diazonium Salts with Bridged Annulenes - Syntheses of New Bridged Heterocycles
15:45	R. Neidlein, C.M. Radke, R. Gottfried, Gg. Hartz, and V. Poignée (Univ. Heidelberg, W. Germany)	136
S-II-20	Electrical and Optical Properties of Heterocyclic Polymers and Their Application as Opto-Electronics Devices
16:00	K. Kaneto, K. Yoshino and Y. Inuishi (Osaka Univ., Japan)	137

August 23 (Tue) Room D

General Sessions (Oral) (G) (4)

Chairman K. C. Joshi (T Shioiri) 12:45-14:15

G-51	Synthesis of Aziridine Derivatives from a-Silyl Carbanion and Oxime Ethers
12:45	T. Konakahara, K. Sato, and M. Matsuki (Sci. Univ. Tokyo, Japan)	138
G-52	A Novel Ring Transformation of Imidazoles to Pyrimidines
13:00	S. Furuya and Y. Furukawa (Takeda Chem. Ind., Ltd., Japan)	139
G-53	Syntheses of Phenyltrifluoromethylacetylenes and Their 1,3-Dipolar Reaction
13:15	Y. Kobayashi, T. Yamashita, and I. Kumadaki (Tokyo Coll. Pharm., Japan)	140
G-54	Synthesis and Reactions of 5(3)-Methylpyrazole-3(5)-aldehyde Thiosemicarbazone, a Potential Antiviral Agent
13:30	N. Saha and N. Mukherjee (Univ. Coll. Sci. Calcutta, India)	141
G-55	Novel Cycloaddition Reactions of Nitroimidazole Derivatives with Diazomethane to Form Imidazopyrazoles
13:45	K. Nagarajan, V. Sudarsanam, S.J. Shenoy, and K. Rama Rao (Hindustan Ciba-Geigy Ltd., India)	142
G-56	Synthesis and Biological Activity of N¹-Salicyloyl-3-methyl-4-(substituted phenylazo)-2-pyrazolin-5-ones.
14:00	Km. Archana Chauhan and C.P. Singh (Sahu Jain Coll., India)	143

Chairman J. Becher (T. Koizumi) 14:45-16:15

G-57	Reaction of 1,2,3-Triazole N-Oxides with Acylating Agents and Nucleophiles
14:45	M. Begtrup (Tech. Univ. Denmark, Denmark)	144
G-58	Trimethylsilyldiazomethane: A New Synthon for the Preparation of 2-Amino-1,3,4-thiadiazoles
15:00	T. Aoyama, A. Fukushima, and T. Shioiri (Nagoya City Univ., Japan)	145
G-59	A Novel Synthesis of Heterocycles by Use of Trithiocyclopropenium Ion
15:15	Z. Yoshida, T. Sugimoto, H. Hirai, E. Seki, N. Nakayama, and S. Yoneda (Kyoto Univ., Japan)	146
G-60	Formation of 2-Alkylthio-substituted 2H-Pyrans in the Reaction of Cyclic 1,3-Diketones with Alkylthiodiphenylcyclopropenium Ions
15:30	H. Yoshida, M. Nakajima, T. Ogata, and K. Matsumoto (Shizuoka Univ. and Kyoto Univ., Japan)	147
G-61	Enhanced Reactivity of Fused Thiirene Sulfoxide in Cycloadditions with Enophiles
15:45	T. Takata, Y. Hanyu, and W. Ando (Univ. Tsukuba, Japan)	148
G-62	A Novel Synthesis of 5-Aryl-3-oxo-2-phenyl-2H,3H-1,2,4-thiadiazoles
16:00	V.K. Verma, Mohd. Ramzan Ali, and R. Singh (Banaras Hindu Univ., India)	149

August 23 (Tue) Room E

General Sessions (Oral) (G) (5)

Chairman S. C. Pakrashi (O. Hoshino) 12:45-14:15

G-63	Synthesis of Some Triazine Derivatives and Their Biological Activity
12:45	A.K.S. Gupta, T. Bhattacharya, and K. Hajela (Lucknow Univ., India)	150
G-64	Synthesis of Novel Sulfur-containing Strong Analgesic (S-Etorphine)
13:00	T. Iwamura, E. Imai, H. Shimizu. T. Kataoka, M. Hori, M. Niwa, M. Nozaki, and H. Fujimura (Gifu Coll. Pharm., Gifu Univ., and Kyoto Coll. Pharm., Japan)	151
G-65	Benzo-separated Xanthines as Phosphodiesterase Inhibitors
13:15	S.W. Schneller and A.C. Ibay (Univ. South Florida, USA)	152
G-66	Naturally Occurring Bioactive Benzo [d e]-1,6-naphthyridines from the Sea Sponge Aaptos aaptos
13:30	H. Nakamura, J. Kobayashi, R. Abe, Y. Ohizumi, and Y. Hirata (Mitsubishi-Kasei Inst. Life Sci. and Meijo Univ., Japan)	153
G-67	Synthesis and Antihypertensive Activity of Some Fused Quinazoline Derivatives
13:45	K.-C. Liu and J.-W. Chern (Nat. Defense Med. Center, Taipei, China)	154
G-68	Synthesis of New Benzopyrano-/4,3-b/-pyridine Ring Systems
14:00	J. Bálint, M. Rákosi, Zs. Szegény, and R. Bognár (BIOGAL Pharm. Works and Hungarian Acad. Sci., Hungary)	155

Chairman J. Chattopadhyaya (T. Itaya) 14:45-16:15

G-69	Synthesis of 4-Deoxy-4-C-ethylphosphinyl-D-ribo- and -L-lyxo-furanoses
14:45	Y. Nakamura, H. Yamamoto, S. Inokawa, and M. Yamashita (Okayama Univ. and Shizuoka Univ., Japan)	156
G-70	Synthesis of L-Idopyranose Derivatives Having a Phosphorus Atom in the Hemiacetal Ring
15:00	M. Yamashita, M. Yamada, K. Tsunekawa, T. Oshikawa, and S. Inokawa (Shizuoka Univ. and Okayama Univ., Japan)	157
G-71	Synthesis of Tunicaminyl Uracil
15:15	T. Suami, H. Sasai, and K. Matsuno (Keio Univ., Japan)	158
G-72	Nⁱⁿ-Mesitylene-2-sulfonyltryptophan, a New Tryptophan Derivative, and Its Application for Peptide Synthesis
15:30	N. Fujii, S. Futaki, K. Yasumura, K. Akaji, and H. Yajima (Kyoto Univ., Japan)	159
G-73	Chemistry of Nucleoside-Amino Acid Adducts and Its Relevance to Photoinduced Lesions
15:45	I. Saito, H. Sugiyama, M.B. Gupta, and T. Matsuura (Kyoto Univ., Japan)	160
G-74	Unconventional Toxic Heterocycles of Clitocybe acromelalga
16:00	K. Konno, H. Shirahama, and T. Matsumoto (Hokkaido Univ., Japan)	161

August 23 (Tue) Room F

General Sessions (Oral) (G) (6)

Chairman A. K. Ganguly (T. Sakamoto) 12:45-14:15

G-75	Synthesis of Quinazolines and 1,4-Benzodiazepines
12:45	J. Bergman, A. Brynolf, and B. Elman (Royal Inst. Tech., Sweden)	162
G-76	Preparation and Reactions of 3-Benzoyl-3,4-dihydro-4-quinazolinecarbonitrile (Quinazoline Reissert Compound)
13:00	T. Higashino, H. Kokubo, and E. Hayashi (Shizuoka Coll. Pharm., Japan)	163
G-77	Novel Mesoionic Heterocycles
13:15	W. Friedrichsen, A. Böttcher, T. Debaerdemacker, G. Möckel, and M. Schildberg (Univ. Kiel and Univ. Ulm, W. Germany)	164
G-78	The Reaction of 5-Benzalimino-1,2,4-triazoles with Substituted Acetyl Chlorides
13:30	J. Reiter, L. Pongó, P. Sohár, and P. Dvortsák (EGYT Pharm. Works and Inst. Drug Res., Hungary)	165
G-79	Palladium Catalyzed Polyhetero-Claisen Rearrangement of 3-Allylthio-1,2,4-triazin-5(2H)-ones
13:45	M. Mizutani, Y. Sanemitsu, Y. Tamaru, and Z. Yoshida (Sumitomo Chem. Co., Ltd., Japan)	166
G-80	Synthesis of Some 3-Hydroxy Metabolites of Psychotropic Trifluoromethyl Analogs of Chlorpromazine. 3-Hydroxy and 3-Methoxy-trifluoroperazine and Their Sulphoxides
14:00	R.L. Mital, M. Anand, H.L. Sharma, A.R. Goyal, A.P. Shukla, and S.B. Gupta (Univ. Rajasthan, India)	167

Chairman R. L. Mital (R. Okazaki) 14:45-16:15

G-81	Synthesis of a Few Novel Purine Analogue Heterocycles (1,9-Dideaza-5-aza-9-thiapurines)
14:45	A. Nayak, S.N. Dehuri, and J.K. Sahu (Sambalpur Univ., India)	168
G-82	A New, Synchronous Construction of Some Fused Pyrimidines by the Reaction of 6‑Arylidenehydrazino-1,3-dimethyluracils with Thionyl Chloride
15:00	M. Ichiba, S. Nishigaki, and K. Senga (Keio Univ., Japan)	169
G-83	1,3-Dipolar Cycloaddition Reactions of Thiazolo[5,4-d]pyrimidine 1-Oxides and Thiazolo [4,5-g]quinazoline 1-Oxides with Acetylenic Esters
15:15	K. Senga, M. Ichiba, H. Kanazawa, and S. Nishigaki (Keio Univ., Japan)	170
G-84	4-Dicyanomethylene-1,4-dihydropyrimidines and Pyrido [4,3-d] pyrimidine-8-carbonitriles from Enaminonitriles
15:30	H. Junek and M. Mittelbach (Karl-Franzens-Univ., Austria)	171
G-85	Heterocyclic Syntheses with Brominated Malononitriles
15:45	R.W. Morrison, Jr. and W.R. Mallory (Burroughs Wellcome Co., USA)	172
G-86	Synthesis of 1,2,4-Triazino[6,5-e]-1,2,4-triazines, 1,2,4-Triazino [6,5-e]-1,2,4-thiadiazines and 1,2,4-Triazino [5,6-e]-1,2,4-thiadiazines
16:00	H. Neunhoeffer and H. Hammann (Tech. Hoch. Darmstadt, W. Germany)	173

August 23 (Tue) Room G

Poster Sessions (P) (1) 16:15-18:00

P-1	A Novel Alkynylation Reaction of Epoxyalcohols
	M. Yamaguchi and I. Hirao (Kyushu Inst. Tech., Japan)	174
P-2	Synthesis of Some Thiaziridine 1,1-Dioxide
	M.M. Kidwai and J. Iqbal (Aligarh Muslim Univ., India)	175
P-3	Synthesis of 1-Benzazocin-5-one Derivative Having Aziridine Ring
	K. Nomura, M. Takeuchi, and K. Masuda (Toyama Med. Pharm. Univ., Japan)	176
P-4	Effective Route to Azetidines from Azetidin-2-ones with the Use of Hydroalanes as Specific Reducing Agents
	M. Yamashita and I. Ojima (Sagami Chem. Res. Center, Japan)	177
P-5	Aluminum Chloride-catalyzed Reactions of 4-Aryl-2-chloro- and 3-Aryl-2-chloro-thiophenes with Some Aromatic Compounds
	T. Sone, K. Sato, and Y. Umetsu (Yamagata Univ., Japan)	178
P-6	An Investigation into the Chlorosulfonation of Acetophenone and Some Derivatives
	D.D. Chapman (Eastman Kodak Co., USA)	179
P-7	Novel Sigmatropic Reactions and Particular Reactivities in the Field of 2-Oxatricyclo[3,3,0,0^4,6]oct-7-ene-3-ones
	A. Valla, M. Giraud, C. Brassy, and B. Bachet (MNHN and CNRS, France)	180
P-8	New Methods for Syntheses of Furanone Derivatives Using Dianions
	K. Tanaka, Y. Isobe, H. Yoda, and A. Kaji (Kyoto Univ., Japan)	181
P-9	Highly Efficient Synthesis of γ-Lactones with Titanium Homoenolates
	E. Nakamura, H. Oshino, and I. Kuwajima (Tokyo Inst. Tech., Japan)	182
P-10	New Methods for the Synthesis of 3(2H)-Furanones and 2(5H)-Furanones
	H. Saimoto, S. Matsubara, K. Oshima, T. Hiyama, and H. Nozaki (Kyoto Univ., Japan)	183
P-11	A New Method for the Synthesis of Functionalized Tetrahydrofurans and Tetrahydropyrans Directed toward the Total Synthesis of Polyether Antibiotics
	Y. Oikawa, K. Horita, I. Noda, and O. Yonemitsu (Hokkaido Univ., Japan)	184
P-12	Silica Gel-promoted γ-Lactonization of γ-Halo Esters
	S. Tsuboi, K. Muranaka, H. Fujita, K. Seko, and A. Takeda (Okayama Univ., Japan)	185
P-13	Facile Preparation of, 2,6-Dimethyl-2,6-tetrahydropyrancarbolactone, a Versatile Intermediate for the Syntheses of (±)-Frontalin, (±)-Cinenic Acid, and (±)-Linaloyl Oxide
	M. Utaka, S. Tsuboi, H. Makino, Y. Oota, and A. Takeda (Okayama Univ., Japan)	186
P-14	Novel Synthetic Methods of Dihydro-4-pyrone, γ-Butyrolactone, and 3(2H)-Furanone by Using α,α'-Dihalo Ketone or α-Monohalo Ketone
	T. Sakai, M. Ishikawa, A. Yamawaki, H. Ito, E. Amano, and A. Takeda (Okayama Univ., Japan)	187
P-15	Reaction of Methyl 12-Hydroxyabietan-8,11,,13-triene-19-oate with Thallium(III) Perchlorate. Formation of a Lactone with a New Rearranged Skeleton
	T. Nakano, M.I. Hernández, and A.T. McPhail (IVIC, Venezuela and Duke Univ., USA)	188
P-16	Reactions of 5-Arylfurfurals and Dialkylphosphonates
	C.-H. Wang, P.-L. Hsiao, Z.-S. Chuang (Northwest Teacher's Coll., China)	189
P-17	New Synthetic Intermediates for Heterocyclic Syntheses from Furfurylidenes
	R. El Gharbi, Y. Le Bigot, M. Delmas, and A. Gaset (Ecole Nat. Sup. Chim., France)	190
P-18	Oxidation Reactions of Bicyclic Pyrrole Derivatives
	Y. Otsuji, N. Ohmura, S. Nakanishi, and K. Mizuno (Univ. Osaka Prefecture, Japan)	191
P-19	Novel Base-catalyzed 1,3-Dipolar Cycloaddition Leading to Pyrrolidines from N-(Phenylthiomethyl) amino Acids
	N. Imai, Y. Terao, K. Achiwa, and M. Sekiya (Shizuoka Coll. Pharm., Japan)	192
P-20	Preparation of Optically Active Phosphonic Acid Derivatives Using Ethyl L-Prolinate and Their Application to Asymmetric Organic Synthesis
	T. Koizumi, M. Iwata, N. Tanaka, K. Hirutani, and E. Yoshii (Toyama Med. Pharm. Univ., Japan)	193
P-21	Stereospecific Synthesis of Nucleoside Cyclic P-Chiral 3',5'-Phosphates and -Phosphoro-thioates
	W. J. Stec (Polish Acad. Sci., Poland)	194
P-22	Syntheses of Five-membered Heterocycles Containing Both Ring and Side-chain Phosphorus Atoms
	Md. Amin, D.G. Holah, A.N. Hughes, and T. Rukachaisirikul (Lakehead Univ., Canada)	195
P-23	Stereoselective Total Synthesis of Pyrrolizidine Alkaloid Bases, (-)-Rosmarinecine and(-)-Isoretronecanol
	K. Tatsuta, H. Takahashi, Y. Amemiya, and M. Kinoshita (Keio Univ., Japan)	196
P-24	Reactions of Trifluoroacetonitrile Ylides with Electron-deficient Olefins and Acetylenes
	K. Tanaka, H. Daikaku, and K. Mitsuhashi (Seikei Univ., Japan)	197
P-25	Reactivity of Isoselenazole Derivatives
	F. Lucchesini, V. Bertini, and A. De Munno (Univ. Calabria and Inst. Chim. Org. Pisa, Italy)	198
P-26	Synthesis of Thiazoline, Thiophene, and 1,3-Dithiolane Using Ethyl 4-Haloacetoacetate
	T. Chiba, H. Sato, and T. Kato (Tohoku Univ., Japan)	199
P-27	C-Alkylation, Alkenylation, and Arylation of 1,2,5-Thiadiazoles
	V. Bertini, A. De Munno, and N. Picci (Univ. Calabria and Inst. Chim. Org. Pisa, Italy)	200
P-28	A New Aromatic Annelation Reaction Utilizing Reaction of Isoxazole with Diiron-nonacarbonyl
	N. Takeuchi, K. Okazaki, J. Ohki, and S. Tobinaga (Showa Coll. Pharm. Sci., Japan)	201
P-29	The Mechanism of Asymmetric Transformation of 2-Substituted Alkanoic Acids
	S. Shibata, H. Matsushita, H. Kaneko, M. Noguchi, M. Saburi, and S. Yoshikawa (Japan Tabacco Salt Public Corp. and Univ. Tokyo, Japan)	202
P-30	Diels-Alder Reaction of Oxazoles
	T. Ibata and S. Nakano (Osaka Univ., Japan)	203
P-31	4,7-Dihydroisoxazolo [5,4-b] pyridines
	T. Yamamori, Y. Hiramatsu, K. Sakai, and I. Adachi (Shionogi & Co., Ltd., Japan)	204
P-32	Air Oxidation Reaction of Diazoalkenes. Efficient Oxygen-transfer Reaction to Give Epoxyketones
	T. Miyashi, M. Kamata, Y. Nishizawa, and T. Mukai (Tohoku Univ., Japan)	205
P-33	Trimethylsilyldiazomethane: A New Synthon for the Preparation of Pyrazoles
	S. Inoue, K. Sudo, T. Aoyama, and T. Shioiri (Nagoya City Univ., Japan)	206
P-34	The Selective Synthesis of Pyrazoles
	C. Kashima and N. Yoshiwara (Univ. Tsukuba and Tokyo Gakugei Univ., Japan)	207
P-36	Photochemistry of the Nitrogen-containing Thiocarbonyl System
	K. Oda, M. Machida, and Y. Kanaoka (Higashi-Nippon-Gakuen Univ. and Hokkaido Univ., Japan)	208
P-37	Sulfur Dichloride as a Sulfur Transfer Reagent in Heterocyclic Synthesis
	M. Komatsu, Y. Ohshiro, and T. Agawa (Osaka Univ., Japan)	209
P-38	Diphenyl Phosphorazidate (DPPA) as a 1,3-Dipole. Formation and Decomposition of Labile 1,2,3-Triazoline Derivatives
	N. Kato, Y. Hamada, and T. Shioiri (Nagoya City Univ., Japan)	210
P-39	Trimethylsilyldiazomethane: A New Synthon for the Preparation of 5-Hydroxy-1,2,3-triazoles
	T. Aoyama, A. Fukushima, and T. Shioiri (Nagoya City Univ., Japan)	211
P-40	Oxidation of 4-Acetyl-2-methylthio-Δ²-1,3,4-thiadiazolines with m-Chloroperbenzoic Acid and Reaction of the Oxidation Products
	S. Kubota, K. Toyooka, M. Shibuya, and Z. Taira (Univ. Tokushima and Tokushima Bunri Univ., Japan)	212
P-41	Heterocyclic Conversion from 5-Amino-1-vinyl-4,5-dihydro-1H-1,2,3-triazoles
	M.M. Ito, Y. Nomura, Y. Takeuchi, and S. Tomoda (Aoyama Gakuin Univ. and Univ. Tokyo, Japan)	213
P-42	Behavior of the Active Aldehyde Generated from Thiamine and Its Derivatives
	K. Hirai and H Sugimoto (Shionogi & Co., Ltd., Japan)	214
P-43	The Oxidation and Reduction of 4-Formyl- and 4-Acetyl-3-arylsydnones
	H.-J. Tien (Nat. Cheng Kung Univ., China)	215
P-44	Synthesis of Sydnone Compounds with Heterocyclic Substituents
	H.-J. Tien, M.-Y. Yeh, T. Goto, T. Fuchigami, and T. Nonaka (Nat. Cheng Kung Univ., China and Tokyo Inst. Tech., Japan)	216
P-45	Reactions of 6-Bromoacetyl-2,3-diphenyl-5-methoxybenzofuran
	A.H.Abd-El-Rahman and M.A. Hanna (Univ. Mansoura, Egypt)	217
P-46	Synthesis and Biological Activities of Some Naphthofurans as Analogues of 7,8‑Benzoflavones
	G. Bastian and R. Royer (Inst. Curie, France)	218
P-47	A New Synthesis of Substituted 2(1H)Pyridinethiones from Enolates of 1,5-Enediones Obtained via Pyrylium Salts.
	J. Becher, F.M. Asaad, and H. Nissen (Odense Univ., Denmark)	219
P-48	Reaction de Kostanecki Appliquee aux Cynnamoyl-pyrones-2
	M. Hamdi, D. Chergui, and Y. Rachedi (Univ. Sci. Tech., Algeria)	220
P-49	Synthesis of Terpenoids from Coumarins
	K.J. Divakar, Y.S. Sanghvi, D.G. Talekar, and A.S. Rao (Nat. Chem. Lab. Pune, India)	221
P-50	A Study on the Oxidative Degradation of Dibenz[b,f]oxepin-11(10H)-one by Field Desorption Mass Spectrometry
	K. Yoshida, S. Arakawa, K. Hino, T. Irie, and H. Uno (Dainippon Pharm. Co., Ltd., Japan)	222

August 23 (Tue) Room H

Poster Sessions (P) (2) 16:15-18:00

P-51	Heterocycles from Photolysis of b-(o-Heteroatom-substituted-phenyl)vinyl Bromides
	T. Kitamura, H. Kawasato, S. Kobayashi, and H. Taniguchi (Kyushu Univ., Japan)	223
P-52	Synthesis of 2-Pyrone Derivatives Using Ketenethioacetal (3)
	Y. Tominaga, A. Ushirogochi, Y. Matsuda, and G. Kobayashi (Nagasaki Univ., Japan)	224
P-53	Structures of Natural Diels-Alder Adducts from the Root Barks of the Mulberry Tree
	T. Fukai, Y. Hano, J. Matsumoto, T. Fujimoto, K. Hirakura, and T. Nomura (Toho Univ., Japan)	225
P-54	Total Synthesis of D-Homoesterone Using Pyran Annelation
	M. Yamamoto, S. Iwasa, K. Suzuki, and K. Yamada (Chiba Univ., Japan)	226
P-55	The Synthesis of Dimeric Macrolides, (±)-Pyrenophorin and (±)-Colletallol
	T. Wakamatsu, S. Yamada, Y. Ohseko, and Y. Ban (Hokkaido Univ., Japan)	227
P-56	New Annelation Methods for Heteroaromatics
	C. Kaneko, T. Naito, N. Shimomura, and Y. Momose (Kanazawa Univ., Japan)	228
P-57	Synthesis of Pyridines and Pyridones
	O.H. Hishmat, M.M.Y. Zohair, and J.A.A. Micky (Nat. Res. Centre and El-Azhar Univ., Egypt)	229
P-58	Acylation of Some Furocoumarin Derivatives
	O. H. Hishmat, and S.S.E.-D. El-Nakkady (Nat. Res. Centre, Egypt)	230
P-59	New Synthesis of Polyheteroarenes via Palladium-Phosphine Complex Catalyzed Cross-coupling
	A. Minato, K. Suzuki, K. Tamao, and M. Kumada (Kyoto Coll. Pharm. and Kyoto Univ., Japan)	231
P-60	Ethyl 2-Cyano-3-ethoxycrotonate in the Gould-Jacobs Reaction
	M.A. Khan and P.G.P. de Oliviera (Inst. Militar Eng., Brasil)	232
P-61	Synthesis of Pyranobenzimidazoles and Pyranoquinoxalines
	M.A. Khan and E.C. Caldas (Inst. Militar Eng., Brasil)	233
P-62	Synthesis of Cycloalkenopyridine by Thermal Rearrangement of Cycloalkanone Oxime O‑Allyl Ether and Synthesis of Alkaloids by Its Application
	H. Irie, J. Koyama, T. Sugita, and Y. Suzuta (Nagasaki Univ. and Kobe Women's Coll. Pharm., Japan)	234
P-63	Photochemistry of 2-Pyridones. Photoaddition with Conjugated Dienes
	Y. Kanaoka, Y. Ikeda, and E. Sato (Hokkaido Univ., Japan)	235
P-64	Dealkylation of Tertiary Amines Using TMS Reagents
	N. Tokitoh, R. Okazaki, and N. Inamoto (Univ. Tokyo, Japan)	236
P-65	Thermal cis-trans Isomerization of 5-Ethyl-2-oxo-4-piperidineacetic Acid and Related Compounds
	T. Fujii, M. Ohba, S. Yoshifuji, and S. Akiyama (Kanazawa Univ., Japan)	237
P-66	Photo-arylation: Synthesis of Aryl- and Heteroarylpyridines by Photolysis of 2‑Halopyridines
	K. Seki, K. Ohkura, C. Yoshida, M. Terashima, and Y. Kanaoka (Higashi-Nippon-Gakuen Univ. and Hokkaido Univ., Japan)	238
P-67	Syntheses and Reactions of Heteroarylorganoboranes
	M. Terashima, M. Ishikura, and M. Kamada (Higashi-Nippon-Gakuen Univ., Japan)	239
P-68	Preparation of Arylamines Using Diphenyl Phosphorazidate (DPPA)
	S. Mori, T. Aoyama, and T. Shioiri (Nagoya City Univ., Japan)	240
P-69	Intramolecular Cyclization Reactions of Cyclic Amine N-Imides Having Unsaturated Substituents
	H. Sashida, M. Hasebe, M. Kato, J. Kurita, and T. Tsuchiya (Hokuriku Univ., Japan)	241
P-70	Indirect Electrooxidation of tert-Amines with RuO₄
	S. Torii, T. Inokuchi, and T. Yukawa (Okayama Univ., Japan)	242
P-71	Oxidation of Heterocyclic b-Dicarbonyl Compounds
	W. Stadlbauer and T. Kappe (Univ. Graz, Austria)	243
P-72	Reaction of Dihydropyrimidine with p-Benzoquinone
	C. Kashima, M. Shimizu, A. Katoh, and Y. Omote (Univ. Tsukuba, Japan)	244
P-73	A New Condensation of Enol Silyl Ethers with Oxime Sulfonates
	K. Maruoka, Y. Matsumura, J. Fujiwara, and H. Ywnainoto (Nagoya Univ., Japan)	245
P-74	A Synthetic Route to the Morphan Ring System from Norbonadiene. The synthesis of the 6,7-Pyridazinoannelated Morphan
	H. Inoue, T. Origuchi, and K. Umano (Univ. Osaka Prefecture, Japan)	246
P-75	Novel Formation of [5]Para-1-azacyclophanes
	H. Takeuchi and Y. Okazaki (Shinshu Univ., Japan)	247
P-76	Double Intramolecular Cycloaddition of 3,6-Bis(2-allylphenoxy)pyridazines
	H. Takeshiba, T. Kinoto, and T. Jojima (Sankyo Co., Ltd., Japan)	248
P-77	Synthesis of Pyrimidine "Analogs" of Natural Polyamines
	G. Menichi, J. Naciri, K. Takagi, and M. Hubert-Habart (Inst. Curie, France)	249
P-78	Photochemical Ring Opening of Pyrimidin-2(1H)-ones
	T. Nishio and Y. Omote (Univ. Tsukuba, Japan)	250
P-79	New Synthetic Methods of Pyrazinoisoquinolines by Simultaneous C-N and C-C Bond Formation
	C.S. Kim, J.H. Kim, and N.J. Lee (Korea Ady. Inst. Sci. Tech., Korea)	251
P-80	A Metal Mediated Synthesis of Chelate Reagent: 2,3,5,6-Tetra(α-pyridyl)pyrazine
	Y. Okamoto, K. Ogura, and T. Kinoshita (Kitasato Univ., Japan)	252
P-81	Abnormal Formation of Pyrazolo[1,5-a]alpyridines via the Desulfurization of Pyrido[1,2-b]-4,1,2-thiadiazine Intermediates
	A. Kakehi, S. Ito, and M. Ito (Shinshu Univ., Japan)	253
P-82	Reactions of Isoquinoline N-Oxide with Cyanoacetic Acid and Related Compounds
	K. Funakoshi, H. Inada, and M. Hamana (Kyushu Univ., Japan)	254
P-83	Syntheses of α,b-Conjugated Carbodiimides and Ketenimines and Their Conversion to Some Heterocycles
	S. Motoki, T. Saito, and M. Nakane (Sci. Univ. Tokyo, Japan)	255
P-84	Synthesis of Pyrimidin-4-ones from Diphenylcyclopropenone and Amidoximes
	M. Takahashi, T. Nogami, and K. Nidaira (Ibaraki Univ., Japan)	256
P-85	Synthesis and Property of 5-(2,2-Difluorovinyl)uracil Derivatives
	K. Hirota, F. Iwami, Y. Kitade, S. Senda, and Y. Maki (Gifu Coll. Pharm., Japan)	257
P-86	Synthesis of Pyrimidines from Perfluoro-2-methyl-2-pentene and Amidines
	I. Ikeda, T. Ineyama, and M. Okahara (Osaka Univ., Japan)	258
P-87	Reaction of Trichloromethyl-N-heteroaromatics with Triphenylphosphine
	S. Konno, E. Takaharu, Y. Sato, S. Fujimura, T. Sakamoto, and H. Yamanaka (Tohoku Univ., Japan)	259
P-88	A Novel Photochemical Ring Transformation of 4-Pyrimidinones. Formation of 5‑Carboxypyrimidinium Betaines
	T. Takahashi, S. Hirokami, M. Nagata, and T. Yamazaki (Toyama Med. Pharm. Univ., Japan)	260
P-89	Pyrazinols and Pyrazinethiols as Acyl Carriers
	A. Ohta, M. Shimazaki, M. Inoue, and Y. Inagawa (Tokyo Coll. Pharm., Japan)	261
P-90	Palladium Catalyzed Reactions of Pyrazines
	A. Ohta, A. Inoue, and Y. Akita (Tokyo Coll. Pharm., Japan)	262
P-91	Regioselective Syntheses of Monosubstituted 2(1H)-Quinoxalinone Derivatives
	G. Sakata, K. Makino, K. Morimoto, and I. Hashiba (Nissan Chem. Ind., Ltd., Japan)	263
P-92	Synthesis and Reactions of 1,2,3-Triazines
	A. Ohsawa, K. Yamaguchi, T. Kaihoh, H. Arai, H. Ohnishi, H. Igeta, and Y. Iitaka (Showa Univ. and Univ. Tokyo, Japan)	264
P-93	Heterocyclic Synthesis via Cu(I)-promoted Arylation of Anionic Species
	H. Suzuki, S.V. Thiruvikraman, and A. Osuka (Ehime Univ., Japan)	265
P-94	Ring Transformation of 1,3-Thiazinones with Hydrazines
	Y. Yamamoto, Y. Azuma, Y. Morita, and S. Ohnishi (Tohoku Coll. Pharm., Japan)	266
P-95	New Synthesis of Cephems
	G. Duguay, J.P. Pradère, H. Quiniou, and A. Reliquet (Lab. Chim. Org. Nantes, France)	267
P-96	Synthesis of Stereoisomeric 2-Imino-1,3-oxazine and 2-Imino-1,3-thiazine Derivatives with Condensed Skeleton
	G. Bernáth, F. Fülöp, and G. Csirinyi (Univ. Med. School Szeged, Hungary)	268
P-97	Synthesis and Stereochemical Studies of Pyrido[2,1-b]quinazolin-11-ones
	F. Fülöp, I. Huber, G. Bernáth, G. Tóth, K. Simon, I. Hermecz, and Z. Mészáros (Univ. Med. School Szeged and CHINOIN Pharm. Chem. Works, Hungary)	269
P-98	Synthesis of Methylene-bridged Saturated 1,3-Benzoxazines
	G. Stájer, E.A. Szabó, G. Bernáth, and P. Sohár (Univ. Med. School Szeged and EGYT Pharm. Works, Hungary)	270
P-99	Reactions of 1,3-Benzothiazine Derivatives with Aroyl Cyanides
	J. Szabó, L. Fodor, E. Szücs, G. Bernáth, and P. Sohár (Univ. Med. School Szeged and EGYT Pharm. Works, Hungary)	271
P-100	Syntheses of Monocyclic 1,4-Diheteroepines from Pyridines via 3‑Azatricyclo[4.1.0.0]heptanes
	J. Kurita, M. Hasebe, K. Iwata, and T. Tsuchiya (Hokuriku Univ., Japan)	272
P-101	Thermal Cycloaddition Reactivity and Regioselectivity of Adamantanethione
	T. Sasaki, S. Eguchi, and T. Katada (Nagoya Univ., Japan)	273
P-102	Synthesis of Some Novel Homoadamantano[4,5]fused Azaheterocycles
	T. Sasaki, S. Eguchi, and Y. Wakata (Nagoya Univ., Japan)	274
P-103	A Novel Synthesis of Benzothiazocines and Their Homologues
	S. Sato, K. Tomita, S. Kobayashi, H. Fujita, and Y. Sato (Sankyo Co., Ltd. and Sankyo Chem. Ind., Japan)	275
P-104	Synthesis of the Cyclobutane Derivatives by Photochemical Cycloaddition of 1,2- or1,4-Benzopyrones to Acetylene
	T. Matsui and M. Nakayama (Miyazaki Univ. and Hiroshima Univ., Japan)	276
P-105	Regioselective Syntheses of 2-Methyl-4H,5H-pyrano[3,2-e][1]benzopyran-4-one and 4,10‑Dihydro-3-hydroxy-3-methyl-1H,3H-pyrano[4,3-b][1]benzopyran-10-one
	M. Yamauchi, S. Katayama, Y. Nakashita, and T. Watanabe (Josai Univ., Japan)	277
P-106	Distribution of Some Coumarins in Different Plants Families Grown in Saudi Arabia
	B.A.H. El-Tawil and F.K.A. El-Beih (King Abdulaziz Univ., Saudi Arabia)	278
P-107	Reactions of Pyridone Derivatives with Isocyanates: Preparation of 1,3,5-Triazine-2,4-dione Derivatives
	Y. Furukawa, M. Sawada, and T. Hanafusa (Osaka Univ., Japan)	279
P-108	Ring-Opening of Methylenedioxyquinolones
	J. Frank and B. Podányi (CHINOIN Pham. Chem. Works, Hungary)	280
P-109	Synthesis and Some Reactions of 2,4-Benzodiazepines
	H. Sawanishi and T. Tsuchiya (Hokuriku Univ., Japan)	281
P-110	Regio- and Stereo-selective Synthesis of Amido-lactones by Anodic Oxidation. The Application for the Synthesis of Eburnamonine and Vincamine
	K. Irie, M. Okita, T. Wakamatsu, Y. Ban, Y. Nishibata, K. Aoe, and K. Kodera (Hokkaido Univ. and Tanabe Seiyaku Co., Ltd., Japan)	282
P-111	The Synthesis and Study of Some Condensed and Uncondensed Bisindoles
	Sh. A. Samsonia (Tbilisi State Univ., USSR)	283
P-112	Synthetic Approach to the Antitumor Antibiotic Labendamycin
	S. Hibino, M. Okazaki, K. Sato, I. Morita, and M. Ichikawa (Fukuyama Univ., Japan)	284
P-113	Synthesis of 6-Thio-L-sorbopyranose
	G. E. M. Moussa, M. N. Basyouni, and A. Saad (Ain Shams Univ., Egypt)	285
P-114	Himalayamin and Limogine. Alkaloids of a New Skeletal Type
	S. K. Talapatra (Univ. Calcutta, India)	286
P-115	The Photochemical Reaction of N-Alkyl-7-azabenzonorbornadienes
	S. Yamada, S. Sato, and M. Ohashi (Univ. Electro-Commun., Japan)	287
P-116	Photo-dearomatization of N-Methylphthalimides
	Y. Kanaoka and Y. Hatanaka (Hokkaido Univ., Japan)	288
P-117	Cyclic Peptides. Syntheses and Properties of Cyclic Hexa- and Octa-peptides Containing Lysine or Aspartic Acid
	Y. Kanaoka, K. Okumura, H. Itoh, Y. Hatanaka, and K. Tanizawa (Hokkaido Univ., Japan)	289
P-118	Reactions of Vinylogous Acyl Cyanides with Enamines
	M. Sakamoto, Y. Akiyama, J. Abe, T. Takano, and T. Kawasaki (Meiji Coll. Pharm., Japan)	290
P-119	A Practical Synthesis of 4-Aryl-1,2,3,4-tetrahydroisoquinolines
	H. Hara, R. Shirai, O. Hoshino, and B. Umezawa (Sci. Univ. Tokyo, Japan)	291
P-120	A Synthesis of Mixed Tetrahydroisoquinoline Dimers via p-Quinol Acetate
	H. Hara, M. Murakata, O. Hoshino, and B. Umezawa (Sci. Univ. Tokyo, Japan)	292

August 24 (Wed) Room A

Symposium IV. New b-Lactams and Other Heterocyclic Antibiotics (2)

Chairman R. G. Micetich (M. Otsuka) 12:45-14:00

S. Inv-15	Monobactams: Ring Activating N-1-Substituents in Monocyclic b-Lactam Antibiotics (Special Invited Lecture)
12:45	W.A. Slusarchyk, T. Dejneka, E.M. Gordon, W.H. Koster, and E.R. Weaver (Squibb Inst., USA)	293
S-IV-9	Asymmetric Synthesis of b-Lactams Using Chiral Five-membered Heterocyclic Compounds Derived from (+)-Tartaric Acid and L-Amino Acids
13:15	N. Ikota and A. Hanaki (Nat. Inst. Radiol. Sci., Japan)	294
S-IV-10	Asymmetric Synthesis of b-Lactam Antibiotics
13:30	A. Nishida, M. Shibasaki, and S. Ikegami (Teikyo Univ., Japan)	295
S-IV-11	Synthesis and Antibacterial Activity of 2-Fluoroalkylthiopenems
13:45	I. Kawamoto, R. Endo, K. Suzuki, and S. Sugawara (Sankyo Co., Ltd., Japan)	296

Chairman C. Hubschwerlen (S. Ikegami) 14:45-16:00

S-IV-12	Synthesis of Penem Antibiotics
14:45	A.K. Ganguly, A. Afonso, V. Girijavallabhan, and S. McCombie (Schering-Plough Corp., USA)	297
S-IV-13	Chemistry of 3-H-1-Carbacephem Compounds
15:00	T. Hirata, A. Sato, and S. Kobayashi (Kyowa Hakko Kogyo Co., Ltd., Japan)	298
S-IV-14	Synthesis of Penem and Cephem Antibiotics Employing Carbene Reaction
15:15	T. Kametani, N. Kanaya, and T. Honda (Hoshi Univ., Japan)	299
S-IV-15	Penicillin-Cephalosporin Conversion with Complete Utilization of All the Framework Elements
15:30	S. Torii, H. Tanaka, T. Siroi, and M. Sasaoka (Okayama Univ., Japan)	300
S-IV-16	A New Method for the Synthesis of 7α-Methoxycephalosporins
15:45	K. Katano, K. Atsumi, K. Nishihata, F. Kai, E. Akita, S. Inoue, and T. Niida (Meiji Seika Kaisha, Ltd., Japan)	301
		301

August 24 (Wed) Room B

Symposium I. Organic Synthesis Utilizing Heterocycles (1)

Chairman J. W. Lown (M. Yokoyama) 12:45-14:15

S-I-1	2-Lithio-2-trimethylsilyl-1,3-oxathiane: A Possible Acyl Dianion Equivalent
12:45	K. Fuji, M. Ueda, and E. Fujita (Kyoto Univ., Japan)	302
S-I-2	Nucleophilic Acylation of Heteroaromatics with Aromatic Aldehydes in the Presence of Benzimidazolium Salt
13:00	A. Miyashita and E. Hayashi (Shizuoka Coll. Pharm., Japan)	303
S-I-3	Synthesis and Properties of Pyrrolo[2,3-d]pyrimidine Derivative and Related Compounds
13:15	Z.S. Salih and W. Pfleiderer (Univ. Baghdad, Iraq and Univ. Konstanz, W. Germany)	304
S-I-4	Reactivity of b-(1-Imidazolyl)enones with Nucleophile
13:30	C. Kashima and T. Tajima (Univ. Tsukuba, Japan)	305
S-Inv-1	Organic Synthesis Utilizing Thiazolidine and the Related Heterocycles (Special Invited Lecture)
13:45	E. Fujita (Kyoto Univ., Japan)	306

Chairman P. K. Kadaba (M. Isobe) 14:45-16:15

S-I-5	Formation of Novel 1-,2-Oxathietanes and Their Chemical Reactivity Including Formal [σ2_s + σ2_a] Cycloreversions and Rearrangement
14:45	J.W. Lown and R.R. Koganty (Univ. Alberta, Canada)	307
S-I-6	Thermal and Photochemical Rearrangements of S-Substituted 2,5-Diphenyl-1,4-dithiins
15:00	K. Kobayashi and K. Mutai (Univ. Tokyo, Japan)	308
S-I-7	Reaction Mechanism of S,N-Double Rearrangement
15:15	M. Yokoyama, M. Kodera, M. Nakamura, and T. Imamoto (Chiba Univ., Japan)	309
S-I-8	Synthesis of N-Heterocycles Using 1,3-Dioxin-4-ones
15:30	M. Sato, H. Ogasawara, S. Komatsu, and T. Kato (Tohoku Univ., Japan)	310
S.Inv-2	New Methods and Reagents for the Synthesis of Heterocyclic Natural Products (Special Invited Lecture)
15:45	I. Ugi, J. Geller, and J. Götz (Tech. Univ. München, W. Germany)	311

August 24 (Wed) Room C

General Sessions (Oral) (G) (7)

Chairman J. Bergman (M. Somei) 12:45-14:15

G-87	Synthesis of 6-Hydroxy-4-(2'-di-n-propylaminoethyl)indole
12:45	T. Lee and J.G. Cannon (Univ. Iowa, USA)	312
G-88	Regioselective Vinylation of Indoles with Olefins and PdCl₂
13:00	Y. Murakami, Y. Yokoyama, and T. Aoki (Toho Univ., Japan)	313
G-89	A New Versatile Synthesis of 4-Nitroindoles
13:15	J. Bergman, P.J.O. Sand, and U. Tilstam (Royal Inst. Tech., Sweden)	314
G-90	Reactions of Ethyl Phenylpropiolate with Indole Derivatives
13:30	M.Y. Shandala, H.A. Khatab, and N.Y. Yahya (Univ. Mosul, Iraq)	315
G-91	A Novel Spiro System: 2-Oxo-1',2',4',5'-tetrahydro-spiro[3H-indole-3,3'-1,2,4,5-tetrazine]-6'-thione
13:45	K.C. Joshi, P. Chand, and A. Dandia (Univ. Rajasthan, India)	316
G-92	A Novel Spiro System: 4',7'-Dihydro-8'-phenyl-spiro[3H-indole-3,6'-[pyrazolo(3,2-d)-1,3,5-thiadiazepine] ]-2,3'(1H)-dione
14:00	K.C. Joshi, P. Chand, and A. Dandia (Univ. Rajasthan, India)	317

Chairman R. Neidlein (Y. Murakami) 14:45-16:15

G-93	Some Reactions and Antibacterial Activities of Some Sulfonylimino-indoline Derivatives
14:45	C.A. Obafemi and D.C. Kolawole (Univ. Ife, Nigeria)	318
G-94	Reaction of 4,6-Dibromo-2-mercaptobenzimidazole with α,b-Bifunctional Compounds
15:00	H.K. Pujari and Brij Raj Sharma (Kurukshetra Univ., India)	319
G-95	Tetrahydro-b-carboline- and b-Carboline-3-carboxamides
15:15	R.T. Coutts, R.G. Micetich, R.A. Locock, G.B. Baker, A. Benderley, J. Pyrozko, T.W. Hall, and T. Dewhurst (Univ. Alberta, Canada)	320
G-96	Synthesis and Chemical Reactivity of Some Benzimidazol-2-yl Hydrazonyl Chlorides
15:30	E.M. Kandeel, H. H. Alnima, and M.H. Elnagdi (Mansoura Univ., Egypt)	321
G-97	Reactions of Haloketenes with Ethyl N-(2-Pyridyl)formimidates and 2‑Arylideneaminopyridines
15:45	N. Katagiri, R. Niwa, and T. Kato (Tohoku Univ., Japan)	322
G-98	Photochemical Formation and Transannular Reactions of Medium-sized Nitrogen Heterocycles
16:00	T. Sheradsky and R. Moshenberg (Hebrew Univ., Israel)	323

August 24 (Wed) Room D

General Sessions (Oral) (G) (8)

Chairman W. Lowe (K. Akiba) 12:45-14:15

G-99	4-Diazomethylcoumarins as Stable Diazoalkanes. Their Facile Isomerization into Benzopyrano[3,4-c]pyrazol-4(3H)-ones
12:45	K. Ito, K. Nagasawa, and J. Maruyama (Hokkaido Inst. Pharm. Sci., Japan)	324
G-100	Triethylamine Mediated Transformation of 3-Formylchromone
13:00	C.K. Ghosh, C. Bandyopadhyay, and N. Tewari (Calcutta Univ., India)	325
G-101	Synthetic and Spectral Investigation on Some Coumarin Derivatives
13:15	D. Ramash, B.M. Sivaram, and M. Srinivasan (Indian Inst. Tech. Madras, India)	326
G-102	5-(2-Nitroethenyl)salicylandides, 6-(2-Nitroethenyl)-3-alkyl-2H-1,3-benzoxazine-2,4-dione, and Related Compounds and Their Antimicrobial and Molluscicidal Activity
13:30	N. Latif, N.S. Girgis, and F.M. Assad (Nat. Res. Centre, Cairo, Egypt)	327
G-103	Photo- and Radiation-induced Alkylation, Hydroxyalkylation, and Alkoxylation of Pyridinecarboxamides in Alcohol
13:45	A. Sugimori, H. Itoh, M. Kanai, N. Kuniyoshi, and M. Nishijima (Sophia Univ., Japan)	328
G-104	Stereoselective Condensation Reactions of 3-Formyl-2(1H)pyridones and Thiones
14:00	J. Becher, T. Johansen, I. Winckelmann, and M.A. Michael (Odense Univ., Denmark)	329

Chairman H. -H. Otto (A. Kubo) 14:45-16:15

G-105	Stereo- and Regioscicctive Aldol-type Reaction of Active Methylene Groups of Nitrogen-containing Heteroaromatic Compounds
14:45	H. Hamana and T. Sugasawa (Shionogi & Co., Ltd., Japan)	330
G-106	On the Facile and Convenient Synthesis of Substituted Pyridylglycols
15:00	A. Clerici and O. Porta (Politec. Milano, Italy)	331
G-107	Introduction of b-Ketoalkyl Groups at 4-Position of Pyridine Using Silyl Enol Ethers
15:15	K. Akiba, Y. Nishihara, and M. Wada (Hiroshima Univ., Japan)	332
G-108	The Pseudo-Gomberg Reaction of 4-Aminopyridine N-Oxide
15:30	S. Saeki, S. Kondo, T. Hayashi, and M. Hamana (Kyushu Univ., Japan)	333
G-109	The Reformatsky Reactions of N-Aryl-2(1H)-pyrimidinones
15:45	A. Katoh, Y. Omote, and C. Kashima (Univ. Tsukuba, Japan)	334
G-110	Vilsmeyer-Haack Reaction on Tetrahydroisoquinolines
16:00	T.R. Kasturi and H.R.Y. Jois (Indian Inst. Sci. Bangalore, India)	335

August 24 (Wed) Room E

General Sessions (Oral) (G) (9)

Chairman G. R. Revankar (I. Saito) 12:45-14:15

G-111	Synthesis of 6,2'-Methylene-cyclouridines
12:45	H. Inoue, T. Sano, S. Shuto, and T. Ueda (Hokkaido Univ., Japan)	336
G-112	Structure of a C-Cyclopyrimidine Nucleoside Derived from a 2'-C-Nitromethyluridine
13:00	T. Ueda, S. Sbuto, and H. Inoue (Hokkaido Univ., Japan)	337
G-113	A Ring Expansion Approach to 1,3-Diazepin-2-one Nucleosides
13:15	V.E. Marquez, K.V.B. Rao, J.V. Silverton, and J.A. Kelley (NIH, USA)	338
G-114	3-N-Acyl Uridines: Preparation and Properties of a New Class of Uracil Protecting Groups
13:30	C.J. Welch and J. Chattopadhyaya (Univ. Uppsala, Sweden)	339
G-115	The 9-Fluorenylmethoxycarbonyl-(FMOC) and 2-Nitrophenylsulfenyl-(NPS) Groups for the Protection of the Base Residues for the Chemical Syntheses of DNA and RNA Fragments
13:45	J. Heikkilä and J. Chattopadhyaya (Univ. Uppsala, Sweden)	340
G-116	Synthesis and Chemistry of Psicofuranosyl and Fructofuranosyl Nucleosides
14:00	A. Grouiller and J. Chattopadhyaya (Inst. Sci. Appl. Lyon, France and Univ. Uppsala, Sweden)	341

Chairman P. C. Srivastava (J. Imai) 14:45-16:00

G-117	Synthesis of 3,4-Disubstituted-1-b-D-ribofuranosylpyrazolo[3,4-d]pyrimidines
14:45	H.B. Cottam, C.R. Petrie, G.R. Revankar, and R.K. Robins (Brigham Young Univ., USA)	342
G-118	Mitsunobu Reaction on Protected Deoxyguanosine and Guanosine
15:00	R. Charubala, T. Trichtinger, and W. Pfleiderer (Univ. Konstanz, W. Germany)	343
G-119	One-pot Synthesis of Oligoribonucleotide from Unblocked Nucleoside
15:15	T. Shimidzu, K. Yamana, A. Murakami, and S. Maikuma (Kyoto Univ., Japan)	344
G-120	Chemical Synthesis of an Undecaribonucleoside Decaphosphate Constituting the 3'‑Terminal Acceptor Stem Sequence of Yeast tRNA^Phe
15:30	M. Kwiatkowski, J. Heikkilä, S. Björkman, H. Seliger, and J. Chattopadhyaya (Univ. Uppsala, Sweden and Univ. Ulm, W. Germany)	345
G-121	Preparation of Blocks for Oligonucleotide Synthesis: A New Approach
15:45	G. Kochak and K. Misra (Univ. Allababad, India)	346

August 24 (Wed) Room F

General Sessions (Oral) (G) (10)

Chairman S. K. Talapatra (K. Kanematsu) 12:45-14:15

G-122	Catalytic Asymmetric Epoxidation by Means of Polyaminoacids in a Triphase System
12:45	S. Colonna, S. Julia, H. Molinari, and S. Banfi (Univ. Milano, Italy and Inst. Quim. Sarria, Spain)	347
G-123	Synthesis of (±)-1-Hydroxy-2,6-diaryl-3,7-dioxabicyclo[3,3,0]octane Lignans
13:00	E. Taniguchi, F. Ishibashi, and Y. Narutomi (Kyushu Univ., Japan)	348
G-124	Enantioselective Synthesis of (-)-Sarracenin Using D-Glucose as Chiral Template
13:15	S. Takano, K. Morikawa, and S. Hatakeyama (Tohoku Univ., Japan)	349
G-125	The Total Synthesis of (+)-Polyzonimine
13:30	T. Sugahara, Y. Komatsu, and S. Takano (Tohoku Univ., Japan)	350
G-126	Total Synthesis of (±)-Sarubicin A (U-58,431)
13:45	Y. Takeuchi, M. Sudani, and E. Yoshii (Toyama Med. Pharm. Univ., Japan)	351
G-127	Syntheses of Pyranoisoflavones from the Corresponding Chalcones with Thallium (III) Nitrate
14:00	M. Tsukayama, Y. Iguchi, T. Horie, M. Masumura, and M. Nakayama (Tokushima Univ. and Hiroshima Univ., Japan)	352

Chairman J. P. Kutney (E. Yoshii) 14:45-16:15

G-128	9,10-Dihydrophenanthropyrans and Pyrones: Novel Phenolic Oxygen Heterocycles of Himalayan Orchids
14:45	P.L. Majumder, S. Joardar, D. Bandyopadhyay, N. Datta, M. Joardar, A.K. Sarkar, and J. Chakraborti (Univ. Coll. Sci. Calcutta, India)	353
G-129	Synthetic Studies of Crowned Morphines: Synthesis and Chemical Transformations of Crowned Thebaine
15:00	I. Fujii, K. Hayakawa, and K. Kanematsu (Kyushu Univ., Japan)	354
G-130	Chemistry of Isoquinolinequinone Antibiotics
15:15	A. Kubo, Y. Kitahara, S. Nakahara, N. Saito, K. Takahashi, and T. Arai (Meiji Coll. Pharm., Chiba Cancer Center Res. Inst., and Chiba Univ., Japan)	355
G-131	Caesalpinine A - A New Skeleton Spermidine Alkaloid from Caesalpinia digyna Rottl.
15:30	S.B. Mahato, N.P. Sahu, and P. Luger (Indian Inst. Chem. Biol., India and Freie Univ. Berlin, W. Germany)	356
G-132	Introduction of a Hydroxyl Group at C-14 of Yohimbine Alkaloids
15:45	E. Yamanaka, S. Kasamatsu, N. Aimi, S. Sakai, D. Ponglux, and S. Wongseripipatana (Chiba Univ., Japan and Chulaiongkorn Univ., Thailand)	357
G-133	Alamaridine, a Novel Isoquinoline Alkaloid from Alangium lamarckii Thw.
16:00	S.C. Pakrashi, R. R. Sinha, A. Bhattacharjya, R. Mukhopadhyay, and E. Ali (Indian Inst. Chem. Biol. Calcutta, India)	358

August 24 (Wed) Room G

Poster Sessions (P) (3) 16:15-18:00

P-121	A Synthesis of (±)-3-Hydroxyhomoaporphines
	O. Hoshino, A. Takahashi, and B. Umezawa (Sci. Univ. Tokyo, Japan)	359
P-122	A Synthesis of (±)-2-Hydroxyhomoaporphines Bearing a Hydroxyl Group on the D-Ring
	O. Hoshino, H. Ogose, M. Inoue, and B. Umezawa (Sci. Univ. Tokyo, Japan)	360
P-123	A Study on the Cyclization of N-Phenylacetyliminium Ions
	S. Kano, T. Yokomatsu, and Y. Yuasa (Tokyo Coll. Pharm., Japan)	361
P-124	Synthesis of N-Heterocycles through N-Oxa-acyliminium Ions
	S. Kano, Y. Yuasa, T. Yokomatsu, and S. Shibuya (Tokyo Coll. Pharm., Japan)	362
P-125	Facile Oxy-Vinyl [1,3]-Shift Promoted by Tetrabutylammonium Fluoride
	T. Sano, J. Toda, and Y. Tsuda (Showa Coll. Pharm. Sci. and Kanazawa Univ., Japan)	363
P-126	Synthesis and Rearrangement Reactions of 3-(1,2,3,4-Tetrahydro-1-isoquinoline-methylene)-Δ²-1,2,4-oxadiazolin-5-ones
	K. Takács (CHINOIN Pharm. Chem. Works, Hungary)	364
P-127	Synthesis and Properties of New Heterotricyclic Quinoxalinones - 3,3a‑Dihydrothiazolo[3,4-a]quinoxalin-4-ones
	E.A. Adegoke and B.I. Alo (Univ. Lagos, Nigeria)	365
P-128	New Ring Transformations of a Spiro[quinoxaline-3,4'-butene] into Novel Quinoxaline Derivatives
	Y. Kurasawa and A. Takada (Kitasato Univ., Japan)	366
P-129	Biosynthesis and Biomimetic Synthesis of Heterocyclic b-Substituted Alanines in Higher Plants
	I. Murakoshi, F. Ikegami, and C. Koide (Chiba Univ., Japan)	367
P-130	Syntheses and Reaction of 2-Chloroformyl-4H-3,1-benzoxazin-4-one
	M. Tsubota and M. Hamashima (Utsunomiya Univ., Japan)	368
P-131	Novel Ring-Closure Reaction between Quinones and Diamines
	M. Matsuoka, K. Takagi, K. Hamano, and T. Kitao (Univ. Osaka Prefecture, Japan)	369
P-132	A Novel and Convenient "One Pot" Synthesis of 5-Substituted Pyrimido(4,5-b)quinolines Including 5-Substituted 5-Deazaflavines
	B. Kokel (Inst. Curie, France)	370
P-133	A Convenient Novel "One Pot" Synthesis of Quinazoline and Benzoxazine Derivatives from Corresponding 2-Amino and 2-Hydroxybenzonitriles via Phosgeniminium Salt Condensation
	B. Kokel (Inst. Curie, France)	371
P-134	Synthetic Studies of the Lythraceae Alkaloids via [3+2]Cycloaddition Reaction
	K. Shishido, K. Tanaka, K. Fukumoto, T. Kametani, and S. Takano (Tohoku Univ. and Hoshi Univ., Japan)	372
P-135	Photochemistry of Hemicyanines. Part II. Syntheses of New Nitrogen Heterocyclic Ring Systems
	K.B. Soroka, A.R. Kósmider, and J.A. Soroka (Polytech. Univ. Szczecin, Poland)	373
P-136	New Syntheses of Antitumor Benzo[c]phenanthridine Alkaloids: Nitidine and Fagaronine
	H. Ishii, T. Ishikawa, I.-S. Chen, and Y. Ichikawa (Chiba Univ., Japan)	374
P-137	Reactions and Properties of New Azonia Compounds Derived from 2‑Methylbenzo[a]quinolizinium Salt
	S. Arai, K. Nagakura, M. Ishikawa, and M. Hida (Tokyo Metropolitan Univ., Japan)	375
P-138	Synthesis of Some b-D-Ribofuranosyl-4,7-methanoindazoles and Pyrazolo[1,5-a]azepines
	S. Nagai and J. Sakakibara (Nagoya City Univ., Japan)	376
P-139	Reactivity of Oxygenated 5-Deazaflavins
	F. Yoneda, Y. Sakuma. and M. Takamoto (Kumamoto Univ. and Takeda Chem. Ind., Ltd., Japan)	377
P-140	Synthesis and Desulfurization of Pyridazino[4,5-e][1,3,4]thiadiazines
	K. Kaji and H. Oda (Gifu Coll. Pharm., Japan)	378
P-141	Some Anionic Reactions of Δ²-Pyrazolines
	A. Jończyk, J. Włostowska, W. Woźniak, and M. Ludwikow (Tech. Univ. Warszawa, Poland)	379
P-142	Novel Aminomethynylation Reaction of Guanidine Heterocyclic System
	S.M.M. Bayomi, A. Tantawy, and M. El-kerdawy (Mansoura Univ., Egypt)	380
P-143	Synthesis of 2-Bromo-2,3-dihydro-1H-pyrazolo[1,2-a]indazolium Bromides and Their Reactions with Alkaline Solations
	Y. Fujimura, Y. Nawata, I. Matsunaga, and M. Hamana (Chugai Pharm. Co., Ltd., Japan)	381
P-144	Synthesis of Macrocyclic Polyethers Containing Cyclobutane Ring by Intramolecular Photocycloaddition
	K. Mizuno, H. Kagano, T. Hashizume, and Y. Otsuji (Univ. Osaka Prefecture, Japan)	382
P-145	Methine Dyes from 1-Alkyl-3-[4-(dialkylamino)phenyl]-2,3-dihydro-2,2-dimethyl-1H- indole-5-carboxaldehydes
	J.J. Krutak and H.M. Beard (Eastman Kodak Co., USA)	383
P-146	Electron Transfer Processes: Reaction of Indolizines with Diazonio Ions or Cripto-Ions
	M. Colonna and M. Poloni (Univ. Bologna, Italy)	384
P-147	Introduction of a Methoxyl Group into the 6-Position of Indoles
	Y. Miyake, M. Kawase, and Y. Kikugawa (Josai Univ., Japan)	385
P-148	Catalytic Transfer Hydrogenation (CTH) of Indoles with Palladium on Carbon in Formic Acid
	M. Kashimura and Y. Kikugawa (Josai Univ., Japan)	386
P-149	Methyl Migration and Demethylation in the 4,5-Dimethylcarbazole Synthesis by Täuber Method
	Y. Tsunashima and M. Kuroki (Shibaura Inst. Tech., Japan)	387
P-150	Synthesis and Characterization of 4,9-Dioxy-1H-benz[f]indoles
	G. Malesani, M.G. Ferlin, G. Chiarelotto, and S. Masiero (Univ. Padova, Italy)	388
P-151	Strong Base Induced Cycloaddition of Homophthalic Anhydrides and Their Heteroaromatic Analogues Leading to Polycyclic Aromatic Compounds
	Y. Tamura, M. Sasho, H. Maeda, T. Tsugoshi, and Y. Kita (Osaka Univ., Japan)	389
P-152	The Photochemistry of Keto-imine Compounds
	Y. Hirai, H. Egawa, and T. Yamazaki (Toyama Med. Pharm. Univ., Japan)	390
P-153	A New Synthetic Method for the Framework of Aspidosperma Alkaloids
	I. Utsunomiya and M. Natsume (Itsuu Lab., Japan)	391
P-154	1-Ethyl-octahydro-indoloquinolizine-1-pyruvic Acid Methyl Ester Oxime. A Key Intermediate for the Synthesis of Ebumane Alkaloids
	A. Nemes, J. Kreidl, Gy. Kalaus, L. Szabó, Cs. Szántay (Chem. Works G. Richter Ltd. and Tech. Univ. Budapest, Hungary)	392
P-155	Syntheses and Reactions of Yohimban Derivatives
	I. Ninomiya, O. Miyata, Y. Hirata, and T. Naito (Kobe Women's Coll. Pharm., Japan)	393
P-156	Total Synthesis of Surugatoxin
	S. Inoue, K. Okada, H. Tanino, K. Hashizume, H. Kakoi, and M. Mizuno (Meijo Univ., Japan)	394
P-157	The Synthesis of Spiro-(cyclopentane-1,3'-oxindol)-derivatives
	T. Kosuge, H. Ishida and Y. Katuyama (Shizuoka Coll. Pharm., Japan)	395
P-158	Studies Directed toward the Total Synthesis of (+)-Griseoviridin
	S. Saito, K. Terao, T. Yamakawa, Y. Matsumoto, R. Nishida, M. Inaba, and T. Moriwake (Okayama Univ., Japan)	396
P-159	Synthesis of 2,3,4,9-Tetrahydrothiopyrano[2,3-b]indoles via a Novel Intramolecular Indole Grignard Reaction
	N. Ishizuka and Y. Makisumi (Shionogi & Co., Ltd., Japan)	397
P-160	A Ring Destruction Approach to Novel Fused Azecine and Azonine Derivatives from Bridgehead Amines
	J. B. Bremner and K.N. Winzenberg (Univ. Tasmania, Australia)	398
P-161	Syntheses and Reactions of 3-Cyanoindolizines
	K. Matsumoto, Y. Ikemi, and T. Uchida (Kyoto Univ. and Fukui Univ., Japan)	399
P-162	Addition Reactions of Condensed Azole Derivatives with Dimethyl Acetylenedicarboxylate. II
	N. Kawahara, T. Nakajima, T. Itoh, and H. Ogura (Hokkaido Inst. Pharm. Sci. and Kitasato Univ., Japan)	400
P-163	The Synthesis of Novel Heterocyclic Compounds. Derivatives of 3H-Indole and Benzofuro[3,3a-d]isoxazole
	K. Takahashi, E. Kaji, and S. Zen (Kitasato Univ., Japan)	401
P-164	Novel Synthesis of Benzofuran and Chroman Derivatives
	K. Matsukawa, T. Ueda, J. Setsune, and T. Kitao (Univ. Osaka Prefecture, Japan)	402
P-165	Typical Electrophilic Reactions of Furopyridines
	S. Shiotani and H. Morita (Univ. Toyama, Japan)	403
P-166	Mechanisms of Photo-induced Isomerization of 4-Oxo-4H-benzisoxazolo[2,3-a]pyridine Derivatives
	T. Yoshida, N. Nagamoto, H. Mizuta, S. Naruto, and H. Uno (Dainippon Pharm. CO., Ltd., Japan)	404
P-167	Steric Effects in the Ring Closure Reactions of 2-(2-Pyridylaminomethylene)succinates
	L. Vasvári-Debreczy, I. Hermecz, and Z. Mészáros (CHINOIN Pharm. Chem. Works, Hungary)	405
P-168	One-Step Synthesis of Pyrrolo[2,3-d]pyrimidin-4-imines
	N.S. Girgis, A. Jørgensen, and E.B. Pedersen (Nat. Res. Centre, Egypt and Odense, Univ., Denmark)	406
P-169	The Reaction of 5-Amino-1,2,4-triazoles with Cyclic b-Keto Esters. A Novel Ring System
	J. Reiter, L. Pongó, P. Sohár, and P. Dvortsák (EGYT Pharm. Works and Inst. Drug Res., Hungary)	407
P-170	Synthesis of Some New 2-Thiox-4-amino[1,2-d]pyrimidine Derivatives
	E.M. Kandeel, S. Elmorsi, and M.T. Zimaity (Mansoura Univ., Egypt)	408

August 24 (Wed) Room H

Poster Sessions (P) (4) 16:15-18:00

P-171	Synthesis of Furopyridine Derivatives for Biological Evaluation
	A. Attia and M.M. Kamel (Nat. Res. Centre, Egypt)	409
P-172	Thia and Ring-opening Analogues of Isoalloxazines
	M. Sako, Y. Kojima, K. Hirota, and Y. Maki (Gifu Coll. Pharm., Japan)	410
P-173	Studies on Reactive Intermediates.III.Reaction of Diketene with 3-Amino-1,2,4-triazines
	M. Daneshtalab and M.H.H. Tehrani (Tehran Univ., Iran)	411
P-174	Synthesis of N⁶-Alkoxy-1,3-dialkyladeninium Salts and an Attempt to Synthesize 1,3‑Dimethyladenine
	T. Fujii, T. Saito, and T. Nakasaka (Kanazawa Univ., Japan)	412
P-175	Synthesis of New Heterocyclic Compounds Containing 1,2,3,4-Tetrahydroisoquinoline or 3-Oxo-tetrahydroisoquinoline Ring
	K. Gáll-Istók, Gy. Deák, and G. Tóth (Hungarian Acad. Sci. and Tech. Univ. Budapest,Hungary)	413
P-176	Reaction of 7-Methoxy-1-phenyl-1H-1,2,3-triazolo[4,5-d]pyridazine 5-Oxide with Nucleophiles
	E. Oishi, Y. Asahina and E. Hayashi (Shizuoka Coll. Pharm., Japan)	414
P-177	Hydrolysis of Nucleosides Related to Fluorescent Minor Components of Phenylalanine Transfer Ribonucleic Acids
	T. Itaya and T. Harada (Kanazawa Univ., Japan)	415
P-178	Synthesis of Phosphorylcholine-bearing Porphinato-Iron Complexes and Their Hemolytic Activities
	E. Hasegawa, Y. Matsushita, K. Eshima, and E. Tsuchida (Taiho Pharm. Co., Ltd. and Waseda Univ., Japan)	416
P-179	Cationic Polar Cycloaddition with α-Chlorosulfides
	Y. Tamura, S. Akai, H.-D. Choi, H. Nakagawa, and H. Ishibashi (Osaka Univ., Japan)	417
P-180	Preparation and Thermolysis of 1,2,3,6-Tetrahydro-1,2-diphenyl-1^λ,2^λ-diphosphorin-1,2-Disulfide
	T. Kawashima, M. Shimamura, and N. Inamoto (Univ. Tokyo, Japan)	418
P-181	Diels-Alder Reaction of 1,4-Benzodithiin 1,1,4,4-Tetraoxide with a Variety of Dienophiles
	J. Nakayama, Y. Nakamura, and M. Hoshino (Saitama Univ., Japan)	419
P-182	Syntheses of Biologically Active Organic Germanium Compounds
	N. Kakimoto, M. Akiba, and T. Takada (Asai Germanium Res. Inst. and Tokyo Coll. Pharm., Japan)	420
P-183	Carbon-13 Chemical Shift of Some Substituted Tetrahydropyrazine
	S.R. Salman, M. Khayate, and S.A. Kanber (Univ. Baghdad, Iraq)	421
P-184	An Account of the Selectivity in the Reactions of Nitrile Oxides with Substituted p‑Benzoquinones by FMO Theory
	T. Hayakawa, K. Araki, and S. Shiraishi (Univ. Tokyo, Japan)	422
P-185	Azinyl-Ylidene Tautomerism of Acylmethyl Azines
	S.A. Stekhova, V.V. Lapachov, O.P. Petrenko, and V.P. Mamaev (Inst. Org. Chem., Novosibirsk, USSR)	423
P-186	Prototropic Rearrangements in Some Aminopyrrolidinones
	J. Lange, J. Rajewski, and W. Koberda (Warsaw Tech. Univ., Poland)	424
P-187	Covalent Hydration of 7,8-Dihydro(3H)pterin
	W.L.F. Armarego, D. Randies, and H. Taguchi (Australian Nat. Univ., Australia, and Kyoto Women's Univ., Japan)	425
P-188	A New Heterocyclisation between Monosubstituted Amidines and α-Bromo-α,b- unsaturated Esters and Ketones
	C. Luu-Duc, A. Marsura, and G. Gellon (UER Pharm. Grenoble, France)	426
P-189	Photochemical Aromatization of 9-Benzyl-1,6-dihydro-2-methyl-8-azapurine through Its Intermediate Intermolecular Photo Dimer ic. Bis-(9-benzyl-1,6-dihydro-2-methyl-8-azapurin-6-yl)
	F. Kázmierczak (Adain Mickiewicz Univ., Poland)	427
P-190	Solution Form of Rubranine and Related Compounds from NMR and X-Ray Studies
	S.K. Arora, V.V. Kane, A.R. Martin, and P. Crews (Univ. Arizona and Univ. California, USA)	428
P-191	Synthesis of Oxygen-bridged Aza[15]annulene Derivatives. Novel Cyclization Reaction Leading to Aza-annulene Frames
	H. Ogawa, M. Kumemura, T. Imoto, I. Miyamoto, H. Kato, S. Takahashi, and Y. Taniguchi (Kyushu Univ. and Kurume Tech. Coll., Japan)	429
P-192	Amphiphilic Phthalocyanine
	T. Kunitake, M. Shimomura, and H. Tsuruta (Kyushu Univ., Japan)	430
P-193	Generation of Chiral Cavity from Achiral Heterocyclophane Host and Achiral Guest
	I. Tabushi, K. Yamamura, H. Nonoguchi, K. Hirotsu, and T. Higuchi (Kyoto Univ. and Osaka City Univ., Japan)	431
P-194	Structure and Cation Selectivity of Unsymmetrical Bis(Crown Ether)_s
	T. Ikeda, K. Kikukawa, and T. Matsuda (Kyushu Univ., Japan)	432
P-195	Crown Ether-based Extraction Photometric Reagents for Alkali Metals
	H. Nakamura, K. Nita, M. Takagi, and K. Ueno (Kyushu Univ., Japan)	433
P-196	Synthesis and Property of Fluorescent Cyclic Polyether Dye Containing a Benzothiazole Unit
	I. Tanigawa, T. Kaneda, and S. Misumi (Osaka Univ., Japan)	434
P-197	Total Synthesis of Jolkinolide A, B, and E
	S. Katsumura and S. Isoe (Osaka City Univ., Japan)	435
P-198	An Application of the Angular Hydroxylation Using Benzeneseleninic Anhydride to the Synthesis of 10β-Hydroxyfuranocremophilanes and Related Compounds
	K. Yamakawa, T. Satoh, S. Takita, T. Iida, and M. Iwasaki (Sci. Univ. Tokyo, Japan)	436
P-199	Alkylations at C-3 and C-5 of Triacetic Acid Lactone and Derivatives
	P. de March, M. Moreno-Mañas, R. Pleixats, and I. Ripoll (Univ. Autónoma Barcelona, Spain)	437
P-200	Synthetic Studies on Antibiotic A23187 (Calcimycin)
	Y. Nakahara, A. Fujita, and T. Ogawa (Inst. Phys. Chem. Res., Japan)	438
P-201	Total Synthesis of (±)-Sesbanine via Directed Metalation of Tertiary Nicotinamides
	M. Iwao and T. Kuraishi (Nagasaki Univ., Japan)	439
P-202	Stereospecific Synthesis of Solenopsin A
	M. Ogawa and M. Natume (Itsuu Lab., Japan)	440
P-203	Aziridine in Alkaloid Synthesis: Syntheses of γ-Lycorane and Erythrina Skeletons
	K. Higashiyama, T. Honda, H. Otomasu, and T. Kametani (Hoshi Univ., Japan)	441
P-204	Conversion of the Protopine N-Oxides to the Benzo[c]phenanthridines and the Secoberbines
	K. Iwasa and N. Takao (Kobe Women's Coll. Pharm., Japan)	442
P-205	Synthesis of Benzindenoazepine Alkaloids, Fumarofine and Fumaritrine
	M. Hanaoka, C. Mukai, S. Sakurai, A. Ashimori, H. Yamagishi, M. Iwasaki, and S. Yasuda(Kanazawa Univ., Japan)	443
P-206	Synthetic Study Directed toward Cyclopiazonic Acid
	M. Somei, S. Tokutake, and C. Kaneko (Kanazawa Univ., Japan)	444
P-207	Synthesis of Cardioactive Steroids. Modified Synthetic Route to Isocardenolide
	M.-J. Shiao (Tunghai Univ., China)	445
P-208	Synthesis of Both the Enantiomers of 2,5-Dimethyl-2-isopropyl-2,3-dihydrofuran, the Sex Pheromone of Hylecoetus dennestoides L.
	T. Ebata and K. Mori (Univ. Tokyo, Japan)	446
P-209	A Stereoselective Synthesis of Daunosamine Utilizing Oxazole Derivatives
	A. Kawai, Y. Hamada, and T. Shioiri (Nagoya City Univ., Japan)	447
P-210	Synthesis and Antimicrobial Activity of Some Heterocycles
	N.F. Eweiss, M.A. Ghannoum, A.A. Bahajaj, and E.A. Elsherbini (Univ. Kuwait, Kuwait)	448
P-211	Synthesis of Some New [1,2]Diazepino[4,5-b]indoles and [1,2]Diazepino[5,6-b] indoles
	A. Monge J.A. Palop, T. Goñi, A. Martínez, and E. Femandez-Alvarez (Univ. Navarra, Spain)	449
P-212	Synthesis and Antibacterial Activity of 2-Phenyl-4H-benzo[b]thiopyran-4-ones (Thioflavones) and Related Compounds
	H. Nakazumi, T. Ueyama, T. Kitaguchi, and T. Kitao (Univ. Osaka Prefecture, Japan)	450
P-213	Synthesis and Bioactivitics of Fused Perimidine Derivatives
	K.-C. Liu and H.-H. Chen (Nat. Defense Med. Center, Taipei, China)	451
P-214	Synthesis and Antibacterial Activity of Thiazolo[5,4-b]pyridine Analogs of Pipemidic Acid
	D.C. Leysen, A. Haemers, and A.J. Vlietinck (Univ. Antwerp, Belgium)	452
P-215	Synthesis and Chemotherapeutical Activity of 5-Cyano-6-aryluracil and 2-Thiouracil Derivatives
	V.J. Ram, A.J. Vlietinck, and D.A.V. Berghe (S.C. Coll. Ballia, India and Univ. Antwerp, Belgium)	453
P-216	A Novel Fluorogenic Substrate for Chymotrypsin. 4-Amino-7-nitrobenzo-2-oxa-1,3-diazole Derivatives
	E. Sato, M. Miyakawa, and Y. Kanaoka (Hokkaido Univ., Japan)	454
P-217	Synthetic Study on Dolastatin 3 Bearing Thiazole Ring
	Y. Hamada, M. Kokuryu, and T. Shioiri (Nagoya City Univ., Japan)	455
P-218	Novel Functions of Porphyrin-Iron Complex as a Model of Cytochrome P-450: Deoxygenation and Reductive Dioxygen Activation
	N. Miyata, T. Santa, and M. Hirobe (Univ. Tokyo, Japan)	456
P-219	Micro-computer-assisted Synthesis Design
	S. Hara and T. Uchimaru (Tokyo Coll. Pharm., Japan)	457
P-220	Heterocycles from Carbohydrate Precursors. Studies on Dehydro-D-Erythro-ascorbic Acid 2-Arylhydrazone 3-Oximes: Conversion into Substituted Triazoles and Isoxazolines
	M.A.El Sekily and S. Mancy (Alexandria Univ., Egypt)	458
P-221	Synthesis of the Phthalimide C-Nucleoside, a Benzologue of Showdomycin
	I. Maeba, F. Usami, and H. Furukawa (Meijo Univ., Japan)	459
P-222	Some New Aspects in the Synthesis of Purine 8-N-Cyclonucleosides
	T. Sasaki, K. Minamoto, Y. Fujiki, and H. Nakade (Nagoya Univ., Japan)	460
P-223	Benzodithiol-2-yl as a New Hydroxyl Protecting Group in Nucleosides
	M. Sekine and T. Hata (Tokyo Inst. Tech., Japan)	461
P-224	Synthesis of Dinucleotide-like Compounds Containing a 5'-Deoxy-S'-adenosineacetic Acid
	T. Kurihara, A. Ota, H. Urata, S. Harusawa, H. Hirano, M. Inoue, and T. Ishida (Osaka Coll. Pharm., Japan)	462
P-225	Synthesis and Attempted Polymerization of N-Arylmaleimides Substituted with Allylamino or Cyclopropylamino Groups at 2- Position
	T.M. Pyriadi and H. Kaleefa (Univ. Baghdad, Iraq)	463
P-226	Synthesis of Some New Heterocyclic Systems of Biological Interest via Reactions with Isothiocyanates
	H.H.S. Alnima (Univ. Salahaldin, Iraq)	464
P-227	Chemical Reactivity of 2-Amino-4-methyl-5-benzothiazole towards Isothiocyanates
	H.H.S. Alnima (Univ. Salahaldin, Iraq)	465
P-228	Photochemical Decomposition of the Oxides of 2,5-Diphenyl-1,4-dithiin Systems in DMSO-A Novel Case of Ring Expansion
	C. L. Gajurel and S. R. Vaidya (Tribhuvan Univ., Nepal)	466
P-229	A Novel Approach towards the Synthesis of the 3,4,5-Trihydro-1,3-diazepin-5-ol Ring Structure
	L. B. Townsend, O.L. Acevedo, and S. Krawczyk (Univ. Michigan, USA)	467
P-230	Reactions of Scienonucleosides with Koshland's Reagents
	A. Jankowsky (Adam Mickiewicz Univ., Poland)	468
P-231	The Synthesis of Glucopyranosylthioureas from Rhodanines
	P. Tovivich and W. Pasakdee (Chulaiongkorn Univ. and Chiangmai Univ., Thailand)	469
P-232	NMR and IR Studies on Cyclic Formals
	L. Arslan (Univ. Salahedeen, Iraq)	470
P-233	Synthesis of Phosphorylated 2,5-Dihydrothiophene 1,1-Dioxides
	C.M. Angelov, D.D. Enchev, and M. Kirilov (Higher Pedagogical Inst., Bulgaria)	471
P-234	Synthesis of Ethynylselenocarboxylic Acids from 1,2,3-Selenadiazoles
	I. Lalezari (Montefiore Med. Center, USA)	472
P-235	A New Synthesis of 4H-1,4-Thiazines and N-Alkyl-4H-1,4-benzothiazines
	G. Liso, G. Trapani, A. Reho, A. Latrofa, and P. Marchini (Univ. Bari, Italy)	473
P-236	N-(2-Acylthio)phenylenamides from Benzothiazolines
	G. Liso, G. Trapani, A. Reho, A. Latrofa, and F. Morlacchi (Univ. Bari, Italy)	474
P-237	Synthesis and Spectroscopic Data of Some Quinolinium Nucleosides
	F. C. Alderweireldt, L. Kemps E. L. Esmans, R. A. Dommisse, and J. A. Lepoivre (Antwerp Univ., Belgium)	475
P-238	On the Synthesis, Reducing and Spectroscopic Properties of Methyl Substituted 1,4‑Dihydronicotinamides
	J.D. Bossaerts, R. A. Dommisse, and F. C. Alderweireldt (Antwerp Univ., Belgium)	476
P-239	Thermal Rearrangement and in vitro Activity of Toromycin against Aerobic Anaerobic Bacteria. Significance of Rearrangement Studies on the Nature of Chrysomycin and the Structure of Gilvocarcin A
	T. Jain, L. Jackman, G. Simolike, and I. Zajac (Smith Kline & French Labs., USA)	477

August 25 (Thu) Room

A Symposium IV. New β-Lactams and Other Heterocyclic Antibiotics (3)

Chairman S. Masamune (M. Sbibasaki) 12:45-14:00

S. Inv-16	The Total Synthesis of Some Non-classical β-Lactams (Special Invited Lecture)
12:45	D.H. Shih, L.D. Cama, F. Baker, and B.G. Christensen (Merck Sharp & Dohme Res. Lab., USA)	479
S-IV-17	A Simple Enantioselective Synthesis of β-Lactams
13:15	C. Hubschwerlen and G. Schmid (F. Hoffmann-La Roche and Co., Ltd., Switzerland)	480
S-IV-18	Enantioscicetive Synthesis of Asparenomyein C by Chemicoenzymatic Approach
13:30	S. Kobayashi, K. Okano, and M. Ohno (Univ. Tokyo, Japan)	481
S-IV-19	Enantioselective Synthesis of Optically Active β-Lactams from D-Glyceraldehyde Acetonide
13:45	H. Matsunaga. T. Sakamaki, H. Nagaoka, and Y. Yamada (Tokyo Coll. Pharm., Japan)	482

Chairman A. G. Brown (M. Ihara) 14:45-15:45

S-IV-20	The Chlorinolysis of Sulfur Containing β-Lactams
14:45	R.G. Micetich, R.B. Morin, C.C. Shaw, and R. Singh (Univ. Alberta, Canada, Bristol-Meyers Co., USA, and Ayerst Lab., Canada)	483
S-IV-21	Synthesis of β-Lactams with Thienamycin-type Sidechain
15:00	M. Sunagawa, K. Goda, M. Enomoto, and A. Sasaki (Sumitomo Chem. Co., Ltd., Japan)	484
S-IV-22	Synthesis of Thienamycin and 2-Alkylthiomethyl-carbapenem (2-Homo-thienamycin) Analogues from 6-Aminopenicillanic Acid
15:15	T. Hiraoka, T. Kobayashi, N. Ishida, M. Shiozaki, K. Hirai, H. Maruyama, S. Sato, C. Tamura, and S. Sugawara (Sankyo Co., Ltd., Japan)	485
S-IV-23	A Chiral Synthesis of Carbapenem Antibiotics from Penicillins
15:30	M. Aratani, K. Sawada, H. Hirai, and M. Hashimoto (Fujisawa Pharm. Co., Ltd., Japan)	486

August 25 (Thu) Room B

Symposium I. Organic Synthesis Utilizing Heterocycles (2)

Chairman I. Ugi (K. Fuji) 12:45-14:15

S-I-9	Quinone Diazide Cyclizations
12:45	G.A. Kraus and J.O. Nagy (Iowa State Univ., USA)	487
S-I-10	Darzens Condensation for Stereocontrol in Sugar Template
13:00	M. Isobe, N. Fukami, and T. Goto (Nagoya Univ., Japan)	488
S-I-11	Enantiocontrolled Synthesis of Natural Products Utilizing Heterocycles
13:15	S. Takano, K. Seya, H. Nuinata, E. Goto, M. Hirama, and K. Ogasawara (Tohoku Univ., Japan)	489
S-I-12	An Approach to Taxane Diterpenes. The Synthesis of the Bicyclo[5.3.1]undecan-4-one Derivatives
13:30	Y. Ohtsuka and T. Oishi (Inst. Phys. Chem. Res., Japan)	490
S. Inv-3	New Routes to Macrocyclic Lactones and Lactams (Special Invited Lecture)
13:45	H.H. Wasserman, R.P. Robinson, C.G. Carter, H. Matsuyama, G.D. Berger, and M.R. Leadbetter (Yale Univ., USA)	491

Chairman G. A. Kraus (K. Ogasawara) 14:45-16:00

S-I-13	Conversion of Azidotriazolines to Tetrazoles via Diazo Transfer Reaction
14:45	P.K. Kadaba (Univ. Kentucky, USA)	492
S-I-14	Synthesis of Bridgehead Nitrogen Heterocycles Utilizing Intramolecular Ring Transformation
15:00	T. Sasaki, E. Ito, and K. Asai (Nagoya Univ., Japan)	493
S-I-15	Utilization of Optically Active 4-Trityloxymethyl-2-buten-4-olide in Photoinduced Asymmetric (2+2) Cycloaddition
15:15	M. Tanaka, K. Tomioka, and K. Koga (Univ. Tokyo, Japan)	494
S.Inv-4	Alkaloid Synthesis (Special Invited Lecture)
15:30	E. Wenkert (Univ. California-San Diego, USA)	495

August 25 (Thu) Room C

General Sessions (Oral) (G) (11)

Chairman F. A. Neugebauer (K. Matsumoto) 12:45-14:15

G-134	Mechanistic and Synthetic Studies of Pyrimidine Ring Formation from α,β-Unsaturated Carbonyl Compounds and Amidines
12:45	A. Weis, M. Bernstein, and D. Zamir (Weizmann Inst. Sci., Israel)	496
G-135	Cyclic Amidines as Convenient Models for the Studies of Proton Transfer Reactions
13:00	A. Weis (Weizmann Inst. Sci., Israel)	497
G-136	Substituent Effect on the Site-selective Reaction of Pyrimidines
13:15	T. Sakamoto, H. Yoshizawa, S. Kaneda, and H. Yamanaka (Tohoku Univ., Japan)	498
G-137	Effect of Thymine Hydroperoxide on DNA Bases
13:30	T. Nagamatsu, F. Yoneda, and S.Y. Wang (Kumamoto Univ., Japan and Johns Hopkin’s Univ., USA)	499
G-138	One Stage Synthesis of Nitrogen-Heterocycles Using Nitriles under High Pressure
13:45	M. Kurabayashi, K. Yanagiya, and M. Yasumoto (Nat. Chem. Lab. Industry, Japan)	500
G-139	Synthesis and Stereochemical Studies of cis and trans Condensed-skeleton 5,6-Dihydro-2-phenyl-4H-1,3-thiazines. An Unexpected Spirocyclization
14:00	L. Simon, S.G. Talpas, F. Fülöp, G. Bernáth, and P. Sohár (Univ. Med. School Szeged and EGYT Pharm. Works, Hungary)	501

Chairman S. V. Kessar (T. Higashino) 14:45-16:15

G-140	Synthesis and Properties of Some New Sulfur Derivatives of Chromone and 4-Quinolone
14:45	W. Löwe, A. Kennemann, A. Kietzmann, and C. Müller-Menke (Free Univ. Berlin, W. Ger- many)	502
G-141	Novel Synthesis of Substituted Quinolines
15:00	M.Z.A. Badr, Y.S. Mobamed, and F.F. Abdel-Latif (Assiut Univ., Egypt)	503
G-142	Intramolecular Alkylazide 1,3-Dipolar Cycloadditon: Application to the Synthesis of Heterocyclic Systems
15: 15	C.-K. Sha, J.-J. Yuang, and S.-L. Ouyang (Nat. Tsing Hua Univ., China)	504
G-143	Transition Metal Catalyzed Novel Route to Quinoline Derivatives Using Alcohols
15:30	Y. Watanabe and Y. Tsuji (Kyoto Univ., Japan)	505
G-144	Studies on the Vilsmeier-Haack Reaction. Reaction of Substituted Acetophenone Oximes
15:45	R.A. Pawar (Sci. Coll., Dhule, India)	506
G-145	Curtius Rearrangement of 1(2H)-Isoquinoline- and 1H-2-Benzopyran-1-one Carboxylic Acids
16:00	I. Atanassova, M. Haimova, E. Stanoeva, and S. Spassov (Univ. Sofia and Bulgarian Acad. Sci., Bulgaria)	507

August 25 (Thu) Room D

General Sessions (Oral) (G) (12)

Chairman Atta-Ur-Rahman (T. Tsuchiya) 12:45-14:15

G-146	Facile Syntheses of Spiro[cycloheptane-1,3'(4H)[2H]thiazolo[3,2-b]-s-tetrazine] and Spiro[cyclooctane-1,3'(4'H)[2H]thiazolo[3,2-b]-s-tetrazine] – Two New Novel Heterocyclic Systems
12:45	H.K. Pujari Sat Narayan, and V. Bindal (Kurukshetra Univ., India)	508
G-147	Cyclodehydration of Some Fused Triazolyl Malondialdehydes to Heteryl Quinolines
13:00	D.S. Deshpande, S.T. Jannawar, S.K. Deshmukh, and A.P. Kulkarni (Sci. Coll., Nanded, India)	509
G-148	Thermal and Photochemical Cyclisation of the Schiff’s Bases and Enamino-imines Derived from 4-Chloro-3-formyl(2H)benzopyrans and Benzothiopyrans
13:15
	K.K. Balasubramanian, K.S. Swaminathan, R. Sai Ganesh, C.S. Venkatachalam, and G.V. Bindumadhavan (Indian Inst. Tech. Madras, India)	510
G-149	Synthesis of Furo and Thieno Fused Phenanthridines
13:30	V. Arisvaran, R.D. Rajan, and P. Shanmugam (Bharathiar Univ., India)	511
G-150	Novel Heterocycles by the Malonic Ester Variation of the Japp-Klingemann Reaction
13:45	R. Heckendorn and A.R. Gagneux (Ciba-Geigy Ltd., Switzeriand)	512
G-151	Hypochromism Encountered in Dimerization of Porphyrin
14:00	H. Kamogawa, T. Nakamura, and S. Miyama (Yamanashi Univ., Japan)	513

Chairman W. Friedrichsen (S. Zen) 14:45-16:00

G-152	Synthesis and Cycloaddition Reaction of 1,2-Aromatic Ring Fused-3-Cyanoindolizines
14:45	K. Matsumoto, T. Uchida, T. Sugi, and T. Kobayashi (Kyoto Univ. and Fukui Univ., Japan)	514
G-153	Synthesis and Cycloaddition Reaction of a Nitrogen-bridged Tetravalent Sulfur Compound, 1,3,6-Triphenylimidazo [1,2-c] thiazole
15:00	O. Tsuge, S. Kanemasa, and T. Hamamoto (Kyushu Univ., Japan)	515
G-154	Synthesis and Structure of Purinophanes with Fully Overlapped Conformation
15:15	Y. Sakata, K. Akahori, F. Hama, and S. Misumi (Osaka Univ., Japan)	516
G-155	Novel Method for Preparation of 6H-1,3-Oxazin-6-ones by Retrodiene Reaction
15:30	G. Bernáth, G. Stájer, E.A. Szabó, and F. Fülöp (Univ. Med. School Szeged, Hungary)	517
G-156	A Novel Generation of Bridgehead Imines via Intramolecular Aza-Wittig Reactions. Synthesis and Reactions of 4-Azahomoadamant-3(4)-ene and 4-Aza-4-homobrend-3(4)‑enes
15:45	T. Sasaki, S. Eguchi, and T. Okano (Nagoya Univ., Japan)	518

August 25 (Thu) Room E

General Sessions (Oral) (G) (13)

Chairman J. Reiter (A. Obia) 12:45-14:15

G-157	The Topliss Manual Approach to the Hansch Design of Biologically Active Heterocycles
12:45	P.K. Kadaba (Univ. Kentucky, USA)	519
G-158	The Synthesis of Novel Tetrahydrofuran Analogs as Molecular Probes for Cholinergic Receptors
13:00	M.C. Lu and M.T. Flavin (Univ. Illinois-Chicago, USA)	520
G-159	Synthesis of Some New Potential Antithyroids
13:15	S.C. Mehra, R. Aron, and A. Saxena (Barcilly Coll., India)	521
G-160	Synthesis and Biological Activity of Some New Coumarin-6-sulphonylamino Acid and Dipeptide Derivatives
13:30	A.M. El-Naggar, A.M. Abd El-Saiam, F.S.M. Ahmed, and T.M. Ibrabim (Al-Azhar Univ.,Egypt)	522
G-161	Synthesis of New Radioiodinated Barbiturates as Potential Brain Imaging Agents
13:45	P.C. Srivastava and F.F. Knapp, Jr. (Oak Ridge Nat. Lab., USA)	523
G-162	Conformational and Chemical Indices Study of Some Biologically Active Compounds
14:00	P.G. Abdul-Ahad (Sci. Res. Council, Iraq)	524

Chairman R. R. Schmidt (T. Miyasaka) 14:45-16:15

G-163	Synthesis and Elucidation of Structure of 1- or 2-R-3-R', R"-Amino-5-amino-1,2,4-triazoles
14:45	J. Reiter, L. Pongó, T. Somorai, and P. Dvortsák (EGYT Pharm. Works and Inst. Drug Res., Hungary)	525
G-164	Some Conversions of 1,2,4-Triazolyl-imino-dithiocarbonic Acid Dimethyl Esters
15: 00	J. Reiter, L. Pongó, and P. Dvortsák (EGYT Pharm. Works and Inst. Drug Res., Hungary)	526
G-165	Correlation of Substituent Constants in Heteroaromatic Esters Using the Lanthanide Shift Reagent Eu(fod)₃
15:15	K. Ranganayakulu and K. Rajeswari (Reg. Eng. Coll., Waranpl, India)	527
C-166	Photochemistry of 1-Azatriptycene
15:30	T. Sugawara and H. Iwamura (Inst. Mol. Sci., Japan)	528
G-167	Synthesis of C 10213-GO, a Potent Antiprotozoal Nitroimidazole Derivative
15:45	K. Nagarajan, V.P. Arya, T. George, and V. Sudarsanam (Hindustan Ciba-Geigy Ltd., India)	529
G-168	Applications of ¹³C NMR Spectroscopy to Assignment of Structures of Isomeric imidazoles and Pyrazoles
16:00	K. Nagarajan, V.P. Arya, V. Sudarsanam, and S.J. Sbenoy (Hindustan Ciba-Geigy Ltd., India)	530

August 25 (Thu) Room F

General Sessions (Oral) (G) (14)

Chairman T. Jain (T. Shibata) 12:45-14:15

G-169	Heterocycles from p-Methoxyphenyl(3,4-xylyl)propen-1-one
12:45	H.H. Moussa and L.M. Chabaka (Nat. Res. Center, Cairo, Egypt)	531
G-170	Synthesis and Absolute Configuration of 2-Alkyl-chroman-4-spiro-hydantoin Derivatives
13:00	Y. Kawakami, Y. Nagai, H. Ono, K. Ueda, T. Sato, and S. Tanaka (Eisai Co., Ltd., Japan)	532
G-171	Base-induced Chemiluminescence of N-Methyl-9-(dicarboalkoxymethyl)acridanes
13:15	N. Suzuki, T. Tsukamoto, and Y. Izawa (Mie Univ., Japan)	533
G-172	Barriers to Rotation and Inversion in meso-1,1'-Bi(2-methylpiperidine)s
13:30	K. Ogawa, Y. Takeuchi, H. Suzuki, and Y. Nomura (Univ. Tokyo, Japan)	534
G-173	Oxidation and Reactivity of Thiopteridines
13:45	W. Pfleiderer, M. Bartke, and A. Heckel (Univ. Konstanz, W. Germany)	535
G-174	Reactions of Some Nitrogen Heterocyclics Containing Donor Functional Groups with Metal Ions
14:00	B. Singh (Patna Univ., India)	536

Chairman S. Colonna (N. Suzuki) 14:45-16:15

G-175	Dithiolane and Dithiane: New Chiroptical Group for Determination of Absolute Confíguration at α- and β-Positions to the Groups by CD
14:45	T. Shibata, T. Ohkura, T. Ohsaka, S. Nislúhara, M. Yanagita, and S. Inayama (Keio Univ., Japan)	537
G-176	1,5-Dialkyl Verdazyls and a New Betaine System
15:00	H. Fischer, F.A. Neugebauer, and R. Siegel (Max-Planck Inst., W. Germany)	538
G-177	Synthesis and Hydrolysis of a New Water Soluble Pyrylium Cation
15:15	A.R. Katritzky, M.De Rosa and N.E. Grzeskowiak (Univ. Florida, USA and Univ. Simón Bolivar, Venezuela)	539
G-178	Tautomeric Structure and Alkylation Products of 3,5-Dioxo-4-phenyl Derivatives of Isoxazole and Pyrazole
15:30	G. Zvilichovsky and M. David (Hebrew Univ., Israel)	540
G-179	Charge Density Activity Correlations in Nicotinoids
15:45	S. Natarajan, V. Kannappan, Sp. Shanmuganathan, and M.J. Nanjan (Presidency Coll., India)	541
G-180	Thermal Analysis of Some Pharmaceutical Compounds
16:00	U. Bhattacharyya, P.P. De, and K. Datta (Indian Inst. Tech., India)	542

Special Invited Lecturers

Special Topic I: Organic Synthesis Utilizing Heterocycles

E. Fujita (Kyoto University, Japan)	306
I. Ugi (Technische Universität München, West Germany)	311
H. H. Wasserman (Yale University, USA)	491
E. Wenkert (University of California at San Diego, USA)	495

Special Topic II: Heterocycles with Novel Functions

R. Raue (Bayer Werk, West Germany)	135
I. O. Sutherland (University of Liverpool, UK)	43
T. G. Traylor (University of California at San Diego, USA)	55
Z. Yoshida (Kyoto University, Japan)	51

Special Topic III: Synthesis of Natural Heterocycles

T. Goto (Nagoya University, Japan)	30
A. S. Kende (University of Rochester, USA)	40
W. N. Speckamp (University of Amsterdam, The Netherlands)	124
S. M. Weinreb (Pennsylvania State University, USA)	33

Special Topic IV: New β-Lactams and Other Heterocyclic Antibiotics

B. G. Christensen (Merck Sharp & Dohme Research Laboratories, USA)	479
S. Masamune (Massachusetts Institute of Technology, USA)	107
M. Ohno (University of Tokyo, Japan)	112
W. A. Slusarchyk (Squibb Institute, USA)	293

Special Topic V: Heterocycles in Anticancer and Antiviral Research

F. Arcamone (Farmitalia, Ricerca Chimica, Italy)	13
M. Ikehara (Osaka University, Japan)	121
J. A. Montgomery (Southern Research Institute, USA)	27
K. A. Watanabe (Sloan-Kettering Institute for Cancer Research, USA)	22