DAY BY DAY PROGRAM

Sunday, July 31

14:00 – 18:00	Registration (San Paolo Palace Hotel)

19:00 – 20:00	Opening Ceremony & Opening Lecture (Massimo Theatre)

19:00 – 19:30	Opening Ceremony

19:30 – 20:00	Opening Lecture
	Chair: Professor Domenico Spinelli (University of Bologna, Italy)

	Professor Giuseppe Silvestri
	Rector of the University of Palermo
	The Rectorate of the University of Palermo. A Piece of History of the Town

20:30 – 22:30	Get-together Party (Botanic Garden)

Monday, August 1

9:00 – 11:00	Plenary Lectures (Sala Orsa)

9:00 – 10:00	Chair: Professor Marco Ciufolini (British Columbia University, Canada)
1-PL1	Professor Malcolm F. G. Stevens
	University of Nottingham – UK
	Azapentacycles via Pyrolyses and Palladium: Search for DNA Telomere Maintenance Inhibitors

10:00 – 11:00	Chair: Professor Mohsen Daneshtalab (Memorial University of Newfoundland, Canada)
1-PL2	Professor Masataka Ihara
	Tohoku University – Sendai – Japan
	Cascade Reactions for Syntheses of Heterocycles

11:00 – 11:30	Coffee Break

11:30 – 13:00	Invited Lectures (Session A, B, C, D)

11:30 – 12:00
Session A	(Sala Orsa)
	Chair: Professor Curt Wentrup (University of Queensland, Australia)
1-IL1	Professor David StC. Black, University of South Wales, Sidney, Australia
	Michelle F. Channon, Glenn C. Condie, Kylie A. Clayton, Jason B. Harper, Karin Pchalek, Tutik Dwi Wahyuningsih, University of South Wales, Sidney, Australia
	Augmented Indoles

Session B	(Sala Nova)
	Chair: Professor Saverio Florio (University of Bari, Italy)
1-IL2	Professor Maurizio Botta, University of Siena, Italy
	Towards New Methodologies for the Synthesis of Biologically Interesting 6-Substituted Pyrimidines and 4(3H)‑Pyrimidinones

Session C	(Sala Orione)
	Chair: Professor Eric Scriven (University of Florida, USA)
1-IL3	Professor Jin K. Cha, Wayne State University, Detroit, USA
	Hee Bong Lee, Hyung Goo Lee, Hyoung Ik Lee, Wayne State University, Detroit, USA
	Studies Toward Total Synthesis of Sarain A

Session D	(Sala Mizar)
	Chair: Professor Branko Stanovnik (University of Lubljiana, Slovenia)
1-IL4	Professor Jose Sepulveda-Arques, University of Valencia, Spain
	González-Rosende M. Eugenia, University Cardenal Herrera-CEU, Valencia, Spain
	Synthetic and Theoretical Studies of Novel Ring Closure and Ring Opening Reactions

12:00 – 12:30
Session A	(Sala Orsa)
	Chair: Professor Curt Wentrup (University of Queensland, Australia)
1-IL5	Professor Johannes Fröhlich, University of Technology, Vienna, Austria
	Doris Domin, Daniel Dangl, Ernst Horkel, Konrad Tiefenbacher, Christian Hametner, University of Technology, Vienna, Austria
	Synthesis of Novel Hetero(macro)cyclic Compounds as Potential Ligands for Organometallics

Session B	(Sala Nova)
	Chair: Professor Saverio Florio (University of Bari, Italy)
1-IL6	Dr. David Laffan, AstraZeneca, Macclesfield, UK
	L. Diorazio, W. E. Stanier, M. W. Senior, K. Leslie, A. C. Barker, N. P. Taylor AstraZeneca, Macclesfield, UK
	Synthesis, Scale-Up and Manufacture of Rosuvastatin Calcium, Crestor

Session C	(Sala Orione)
	Chair: Professor Eric Scriven (University of Florida, USA)
1-IL7	Professor Akira Matsuda, Hokkaido University, Sapporo, Japan
	Kazuyuki Kuramoto, Sadao Hikishima, Noriaki Minakawa
	Hokkaido University, Sapporo, Japan
	New Four H-Bonding Motifs in Oligodeoxyribonucleotides

Session D	(Sala Mizar)
	Chair: Professor Branko Stanovnik (University of Lubljiana, Slovenia)
1-IL8	Professor Giovanni Petrillo, University of Genova, Italy
	Lara Bianchi, Carlo Dell’Erba, Massimo Maccagno, Fernando Sancassan, Elda Severi, Cinzia Tafani, University of Genova, Italy
	Stefano Morganti, Egon Rizzato, Domenico Spinelli, University of Bologna, Italy
	Nitrobutadienes from β-Nitrothiophenes: Valuable Building-Blocks in the Overall Ring-Opening / Ring-Closure Protocol to Homo- or Hetero-cycles

12:30 -13:00
Session A	(Sala Orsa)
	Chair: Professor Curt Wentrup (University of Queensland, Australia)
1-IL9	Professor Koichi Narasaka, University of Tokyo, Japan
	Mitsuru Kitamura, University of Tokyo, Japan
	Synthesis of Azaheterocycles by One Electron Reduction of Oximes

Session B	(Sala Nova)
	Chair: Professor Saverio Florio (University of Bari, Italy)
1-IL10	Professor Alba Chimirri, University of Messina, Italy
	Maria Letizia Barreca, Laura De Luca, Stefania Ferro, Anna-Maria Monforte, Angela Rao, University of Messina, Italy
	Computational and Synthetic Approaches for the Discovery of HIV-1 Integrase Inhibitors

Session C	(Sala Orione)
	Chair: Professor Eric Scriven (University of Florida, USA)
1-IL11	Dr. Alan Aitken, University of St Andrews, UK
	Steven D. McGill, Lynn A. Power, University of St Andrews, UK
	Synthetic Applications of Chiral 1,3-Dioxolan-4-ones and 3-Acyloxazolidine-5-ones

Session D	(Sala Mizar)
	Chair: Professor Branko Stanovnik (University of Ljubljana, Slovenia)
1-IL12	Professor Jurij Svete, University of Ljubljana, Slovenia
	Utilisation of Chiral Enaminones and Azomethine Imines in the Synthesis of Functionalised Pyrazoles

13:00 – 13:30
	(Sala Orsa)
	Chair: Professor Girolamo Cirrincione (University of Palermo)
	Professor Alan R. Katritzky, University of Florida, Gainesville, USA
	ARKIVOC: The First Five Years

13:30 – 15:00	Lunch

15:00 – 17:15	Oral Contributions (Session A, B, C, D)

17:15 – 18:45	Coffee Break & Poster Session 1-PO1 ÷ 1-PO92

20:00 – 23:00	Concert at Monreale Dome & Dinner

Tuesday, August 2

9:00 – 11:00	Plenary Lectures (Sala Orsa)

9:00 – 10:00	Chair: Professor Henk C. van der Plas (University of Wageningen, Belgium)
2-PL3	Professor José Barluenga
	University of Oviedo – Spain
	New Heterocyclization Reactions with Fischer Carbene Complexes

10:00 – 11:00	Chair: Professor Jan M. Bakke (Norwegian University of Science and Technology, Norway)
2-PL4	Professor Tsutomu Ishikawa
	Chiba University – Japan
	Roads to New Guanidine Chemistry from 2-Imidazolidines Through 2‑Chloroamidinium Derivatives

11:00 – 11:30	Coffee Break

11:30 – 12:30	Plenary Lecture (Sala Orsa)

11:30 – 12:30	Chair: Professor Margaret Brimble (University of Auckland, New Zealand)
2-PL5	Professor Mark Rizzacasa
	University of Melbourne – Australia
	Total Synthesis of Spiroketal Containing Natural Products: Kinetic vs. Thermodynamic Approaches

12:30 – 13:00	Invited Lectures (Session A, B, C, D)

Session A	(Sala Orsa)
	Chair: Professor Satoshi Hibino (Fukuyama University, Japan)
2-IL13	Professor Mitsuo Komatsu, Osaka University, Japan
	1,4-Sila/Stannatropy: A Potential Strategy for Generation of 1,3-Dipoles

Session B	(Sala Nova)
	Chair: Professor Paolo E. Todesco (University of Bologna, Italy)
2-IL14	Professor Giuseppe Guanti, University of Genova, Italy
	Design and Synthesis of Heterocycle Fused Enediyne Prodrugs Activable at Will

Session C	(Sala Orione)
	Chair: Dr. Stanley Lang (Valeant Pharmaceuticals Int., USA)
2-IL15	Professor P. Andrew Evans, Indiana University, Bloomington, USA
	New Organometallic Mediated Carbocyclization Reactions for the Construction of Complex Natural Products

Session D	(Sala Mizar)
	Chair: Professor Anna Maria Almerico (University of Palermo)
2-IL16	Dr. Panayiotis A. Koutentis, University of Cyprus, Nicosia, Cyprus
	Irene C. Christoforou, Sophia S. Michaelidou, University of Cyprus, Nicosia, Cyprus
	1,2,3-Dithiazole Chemistry in Heterocyclic Synthesis

13:00 – 15:00	Lunch

15:00 – 17:00	Oral Contributions (Session A, B, C, D)

17:00 – 18:30	Coffee Break & Poster Session 2-PO1 ÷ 2-PO94

Wednesday, August 3

9:00 – 11:00	Plenary Lectures (Sala Orsa)

9:00 – 10:00	Chair: Professor Alan R. Katritzky (University of Florida, USA)
3-PL6	Professor Tomas Hudlicky
	Brock University – St. Catharines – Canada
	Chemoenzymatic Synthesis of Complex Natural and Unnatural Products: Morphine, Pancratistatin, and Their Analogs

10:00 – 11:00	Chair: Professor Marco Ciufolini (British Columbia University, Canada)
3-PL7	Professor Dennis P. Curran
	University of Pittsburgh – USA
	Fluorous Mixture Synthesis of Murisolin and Passifloricin Stereoisomer Libraries

11:00 – 11:30	Coffee Break

11:30 – 12:30	Plenary Lecture (Sala Orsa)

11:30 – 12:30	Chair: Professor Giuseppe Ronsisvalle (University of Catania, Italy)
3-PL8	Professor Pier Giovanni Baraldi
	University of Ferrara – Italy
	DNA Minor Groove Binders as Potential Antitumor Agents

12:30 – 13:00	Invited Lectures (Session A, B, C, D)

Session A	(Sala Orsa)
	Chair: Professor Oliver C. Kappe (Karl-Franzen University, Austria)
3-IL17	Professor Peter Bäuerle, University of Ulm, Germany
	Conjugated Oligo- and Polyheterocycles for Nanoelectronics

Session B	(Sala Nova)
	Chair: Professor Guy Queguiner (University of Rouen, France)
3-IL18	Dr. Serge Halazy, Serono P.R.I, Geneva, Switzerland
	Designing Heterocyclic Selective Kinase Inhibitors: from Concept to New Drug Candidates

Session C	(Sala Orione)
	Chair: Professor Jan Bergman (KI, Biosciences at Novum, Sweden)
3-IL19	Professor Erick M. Carreira, ETH, Zürich, Switzerland
	Natural Products Inspired Studies in Asymmetric Synthesis

Session D	(Sala Mizar)
	Chair: Professor Grzegorz Mloston (University of Lodz, Poland)
3-IL20	Professor Vladimir I. Minkin, Rostov University, Russia
	Vitaly N. Komissarov, Yurii A. Sayapin, Rostov University, Russia
	Synthesis of 1,3-Tropolone and Fused Heterocycle Derivatives by Acid-Catalyzed and Photoreactions of o-Quinones with Quinolines and Benzimidazoles

13:00 – 14:00	Lunch

14:00- 23:00	Congress Excursion (Selinunte) & Dinner at “Baglio Trinità”

Thursday, August 4

9:00 – 11:00	Award Lectures (Sala Orsa)

9:00 – 10:00	Chair: Professor Oliver C. Kappe (Karl-Franzen University, Austria)
4-AL1	Professor Alois Fürstner
	Max-Plank-Institut für Kohlenforschung – Mülheim/Ruhr – Germany
	Recent Studies on Pyrrole Alkaloids

10:00 – 11:00	Chair: Professor Steven M. Weinreb (Pennsylvania State University, USA)
4-AL2	Professor Larry E. Overman
	University of California – Irvine – USA
	Recent Studies in Alkaloid Total Synthesis

11:00 – 11:30	21^St ICHC Announcement & Coffee Break

11:30 – 13:00	Invited Lectures (Session A, B, C, D)

11:30 – 12:00
Session A	(Sala Orsa)
	Chair: Professor Joseph P. Konopelski (University of California S.C., USA)
4-IL21	Professor Phil S. Baran, The Scripps Research Institute, La Jolla, USA
	The Catalytic Cycle of Discovery in Total Synthesis

Session B	(Sala Nova)
	Chair: Professor Lyle Castle (Idaho State University, USA)
4-IL22	Dr. Vittorio Farina, Boehringer Ingelheim, Ridgefield, USA
	Process Development of Novel Hepatitis C Protease Inhibitors

Session C	(Sala Orione)
	Chair: Professor Mikael Begtrup (Danish University of Pharmaceutical Sciences, Denmark)
4-IL23	Professor Volker Jäger, University of Stuttgart, Germany
	Leo Redcliffe, Mahendra Gulla, Lars Bierer, University of Stuttgart, Germany
	Carbohydrate Mimetics and Analogues: New Glycosidase Inhibitors

Session D	(Sala Mizar)
	Chair: Professor Josè A. S. Cavaleiro (University of Aveiro, Portugal)
4-IL24	Professor Milan Potacek, Masaryk University, Brno, Czech Republic
	Ways to Complex Fused Heterocycles and their Unexpected Transformations

12:00 – 12:30
Session A	(Sala Orsa)
	Chair: Professor Joseph P. Konopelski (University of California S.C., USA)
4-IL25	Dr. Frank Narjes, IRBM Merck Sharp & Dome, Pomezia, Italy
	Inhibitors of the Hepatitis C Virus RNA-dependent RNA Polymerase: Synthesis and SAR of Active Site and Allosteric Inhibitors

Session B	(Sala Nova)
	Chair: Professor Lyle Castle (Idaho State University, USA)
4-IL26	Professor Franklin A. Davis, Temple University, Philadelphia, USA
	Bin Yang, Junyi Zhang, Temple University, Philadelphia, USA
	Asymmetric Synthesis of Heterocycles Using Sulfinimines (N-Sulfinyl Imines)

Session C	(Sala Orione)
	Chair: Professor Mikael Begtrup (Danish University of Pharmaceutical Sciences, Denmark)
4-IL27	Professor Jacques Royer, University of Paris 5, France
	New Developments in the Asymmetric Synthesis of Heterocyclic Natural Products

Session D	(Sala Mizar)
	Chair: Professor Josè A. S. Cavaleiro (University of Aveiro, Portugal)
4-IL28	Professor Amin F. M. Fahmy, Ain Shams University, Cairo, Egypt
	Heterocycles as Versatile Building Blocks in Different Synthetic Strategies

12:30 – 13:00
Session A	(Sala Orsa)
	Chair: Professor Joseph P. Konopelski (University of California S.C., USA)
4-IL29	Dr. Alcide D. Perboni, Glaxo Smith & Kline, Verona, Italy
	K. Cardwell, R. Barrett, M. Berry, D. Caine, J. Cook, J. Cooke, R. Cox, S. Hermitage, A. Hodgson, R. Lawrence, P. Ravenscroft, Glaxo Smith & Kline, Stevenage, UK
	G. Guercio, Glaxo Smith & Kline, Verona, Italy
	Synthetic Routes to 3-Alkyl-hexahydro-pyrrolo[3,2-b]pyrrol-2-one

Session B	(Sala Nova)
	Chair: Professor Lyle Castle (Idaho State University, USA)
4-IL30	Dr. Guy R. Humphrey, Process Research Department, Merck & Co., Rahway, USA
	Mike Hillier, Michel Journet, Jeff Kuethe, Peter Maligres, Jeff Marcoux, J. Chris McWilliams, David Tellers, Audrey Wong, E. J. J. Grabowski, David Hughes, Process Research Department, Merck & Co., Rahway, USA
	New Developments in Fischer Indole Chemistry Practical, Highly Convergent, Asymmetric Syntheses of DP Antagonists

Session C	(Sala Orione)
	Chair: Professor Mikael Begtrup (Danish University of Pharmaceutical Sciences, Denmark)
4-IL31	Professor Viresh H. Rawal, University of Chicago, USA
	Total Synthesis of Mycalamide A

Session D	(Sala Mizar)
	Chair: Professor Josè A. S. Cavaleiro (University of Aveiro, Portugal)
4-IL32	Professor Teresa M. V. D. Pinho e Melo, University of Coimbra, Portugal
	Exploiting Azafulvenium Methides Chemistry

13:00 – 15:00	Lunch

15:00 – 17:00	Oral Contributions (Session A, B, C, D)

17:00 – 18:30	Coffee Break & Poster Session 4-PO1 ÷ 4-PO94

18:30 – 19:00	ISHC Meeting

20:30 – 23:00	Banquet at Palazzo Guglielmo, Monreale

Friday, August 5

9:00 – 11:00	Plenary Lectures (Sala Orsa)

9:00 – 10:00	Chair: Professor Gyorgy Hajos (Chemistry Research Centre, Hungary)
5-PL9	Professor Peter Mátyus
	Semmelweis University – Budapest – Hungary
	New Strategies for the Syntheses of Diazino-fused Ring Systems

10:00 – 11:00	Chair: Professor Hans Neunhoeffer (Technical University of Darmstadt – Germany)
5-PL10	Professor Michael Reggelin
	Technical University of Darmstadt – Germany
	Asymmetric Synthesis of Highly Substituted Aza(poly)cyclic Compounds from 2-Alkenylsulfoximines

11:00 – 11:30	Coffee Break

11:30 – 12:30	Plenary Lecture (Sala Orsa)

11:30 – 12:30	Chair: Professor Domenico Spinelli (University of Bologna, Italy)
5-PL11	Professor Marcello Tiecco
	University of Perugia – Italy
	Enantioselective Synthesis of Heterocyclic Compounds Mediated by Organoselenium Reagents

12:30 13:00	Closing Ceremony

MONDAY, AUGUST 1		ORAL CONTRIBUTIONS

15:00 – 17:00
Session A	(Sala Orsa)
	Chair: Professor Maurizio Bruno (University of Palermo, Italy)

1A-OC1	Imidoylketenes: Generation and [4+2] Cycloaddition to give 2‑Pyridones
	M. Sato, Y. Morie, S. Akahane, Y. Suzuki, K. Ikeda (University of Shizuoka, Japan) msato@u-shizuoka-ken.ac.jp

1A-OC2	Stereoselective Cycloaddition Reaction of Functionalized Azomethine Ylides Generated by 1,2-Hydrogen Shift of Heterocyclic Aldimines
	M. Noguchi, K. Kawashima (Yamaguchi University, Japan) noguchi@yamaguchi-u.ac.jp

1A-OC3	An Improved Synthesis of Isonitrosoacetanilides: Valuable Intermediates in the Synthesis of Isatins
	G.W. Rewcastle, H.S. Sutherland, C.A. Weir, A.G. Blackburn, W.A. Denny (University of Auckland, New Zealand) g.rewcastle@auckland.ac.nz

1A-OC4	Catalytic Enolization with Metal Acetates in Alcohols and Enantioselective Michael Additions under Multiple Activation Conditions
	S. Kanemasa, M. Hasegawa (Kyushu University, Japan) kanemasa@cm.kyushu-u.ac.jp

1A-OC5	Bromoisocyanuric Acid Sodium Salt as a Brominating Reagent for Aromatic Amino Acid under Strong Acidic Condition
	Y. Yokoyama, M. Satou, T. Yamaguchi, E. Kobayashi, H. Okuno, Y. Murakami (Toho University, Chiba, Japan) yokoyama@phar.toho-u.ac.jp

1A-OC6	Cyclobutendione Derivatives as Building-blocks for Heterocyclic Synthesis
	E. Schaumann, K. Benda, G. Oppermann, H.W. Moore, M. Stranberg (Clausthal University of Technology, Germany) ernst.schaumann@tu-clausthal.de

1A-OC7	*The First Enantioselective Synthesis of the Anti-Helicobacter Pylori* Agent Spirolaxine Methyl Ether**
	M.A. Brimble, J. Robinson (University of Auckland, New Zealand) m.brimble@auckland.ac.nz

1A-OC8	Novel Pd-Catalyzed Stereospecific Route to the Synthesis of Variously Functionalized THBC and THGC Compounds through Intramolecular AAA of Indoles
	M. Bandini, A. Melloni, R. Sinisi, S. Tommasi, A. Umani-Ronchi (University of Bologna, Italy) marco.bandini@unibo.it

1A-OC9	Dimethylzinc-initiated Radical Reaction of Cyclic Ethers with Arylamines
	Y. Yamamoto, M. Maekawa, T. Akindele, K. Yamada, K. Tomioka (Kyoto University, Japan) tomioka@pharm.kyoto-u.ac.jp

Session B	(Sala Nova)
	Chair: Professor Maurizio Botta (University of Siena, Italy)

1B-OC1	Change of 6-Exo/7-endo Selectivity in Radical Cyclization
	A. Kamimura, Y. Ohara (Yamaguchi University, Japan) ak10@yamaguchi-u.ac.jp

1B-OC2	A Synthetic Route to the Core Structures of Halichlorine and Pinnaic Acid Using a Spirocyclic Nitrone
	V. Caprio, S.H. Yang (University of Auckland, New Zealand) v.caprio@auckland.ac.nz

1B-OC3	Green Synthesis and Enantioselective Heterogeneous Hydrogenation of Bicyclo[2.2.2]octene Derivates into Substituted a-Amino Acid Derivatives
	K. Kranjc, M. Martelanc, S. Polanc, M. Kočevar, F. Iosif, S. Coman, V. Parvulescu (University of Ljubljana, Slovenia) marijan.kocevar@fkkt.uni-lj.si

1B-OC4	Total Synthesis of Mycalamide A
	N. Kagawa, M.Ihara, M. Toyota (Osaka Prefecture University, Japan) toyota@c.s.osakafu-u.ac.jp

1B-OC5	*Asymmetric Acylation of Sec-Alcohols by a New Class of Pyridine Catalyst Having a Conformation Switch System*
	S.Yamada, T. Misono, Y. Iwai, A. Masumizu (Ochanomizu University, Tokyo, Japan) yamada@cc.ocha.ac.jp

1B-OC6	An Explanation of the Relative Rates of Nucleophilic Substitution in Small-ring Nitrogen Heterocycles
	H.D. Banks (Aberdeen Proving Ground, MD, USA) harold.banks@us.army.mil

1B-OC7	Stereoselective Total Synthesis of Streptolic Acid and Tirandalydigin
	M. Miyashita, Y. Iwata, N. Maekawara, K. Tanino (Hokkaido University, Japan) miyasita@sci.hokudai.ac.jp

1B-OC8	Synthesis of Enantiopure Substituted Tetrahydrofuranols by Radical Cyclization Reactions
	F. Marini, M. Tiecco, L. Testaferri, S. Sternativo, C. Santi, L. Bagnoli A. Temperini (Università di Perugia, Italy) marini@unipg.it

1B-OC9	Chiral N-heterocyclic Carbene Catalyzed Asymmetric Acylation of Secondary Alcohols
	Y. Suzuki, K. Muramatsu, K. Yamauchi, M. Sato (University of Shizuoka, Japan) suzuyumi@u-shizuoka-ken.ac.jp

Session C	(Sala Orione)
	Chair: Professor Francesco Dall’Acqua (University of Padova, Italy)

1C-OC1	New Annulated Oligothiophenes. Synthesis and Chemistry
	V. Nenajdenko, K. Chernichenko, V. Sumerin, A. Moiseev, E. Balenkova (Moscow State University, Russia) nen@acylium.chem.msu.ru

1C-OC2	New Rearrangement of 1,2,3-Thiadiazole. The Synthesis of [1,2,3]Thiadiazolo[5',4'-2,3]pyrido[2,1-c][1,4]oxazine
	Y. Morzherin, L. Dyudya, P. Kropotina, K. Malysheva, T.V. Gluhareva (Urals State Technical University, Russia) morjerine@htf.ustu.ru

1C-OC3	On the Reactivity of Thiolactam in Indole Series: New Approaches to the Bioactive Natural Alkaloid Product Rutaecarpine, its Homologues and Corresponding Pyridones via the Tandem Processes
	A. Hamid,H. Elomri,A. Daïch. (Université du Havre, France) kareemhamid@yahoo.com

1C-OC4	Recent Progress in the Synthesis of Heterocyclic Rings from Conjugated Azoalkenes
	O. A. Attanasi, P. Filippone (Università degli Studi di Urbino, Italy) filippone@uniurb.it

1C-OC5	Porphyrins as Dienophiles: Synthesis of Novel Chlorin Derivatives
	J.A.S. Cavaleiro, A.M.G. Silva, M.G.P.M.S. Neves, A.C. Tomé and A.M.S. Silva (University of Aveiro, Portugal) jcavaleiro@dq.ua.pt

1C-OC6	Novel Synthesis of 3-Alkyl- and 3-(w-Hydroxyalkyl)oxindoles
	B. Volk, G. Simig (Egis Pharmaceuticals Ltd., Budapest, Hungary) simig.gyula@egis.hu

1C-OC7	Novel Strategies in Assembly of Heterocycles: One-Pot Syntheses of Compounds for Target-biased Screening Libraries
	A. Kiselyov, A.P. Ilyn,I.A. Okun, S.E. Tkachenko, A.V. Ivachtchenko (Small Molecule Drug Discovery, San Diego, USA) ask@chemdiv.com

1C-OC8	Synthesis and Scaffold Decoration of Dihydropyrimidine Derivatives by Microwave-assisted Solution Phase Synthesis
	D. Dallinger, C.O. Kappe (Karl-Franzens-University Graz, Austria) do.dallinger@uni-graz.at

1C-OC9	The Effect of Temperature on the Synthesis of Substituted 5,6 and 7-Azaindoles via the Hemetsberger – Knittle Reaction
	Y. Leblanc, C. Dufresne, N. Lachance, J.-P. Leclerc, M. Boisvert, P. Roy (Merck Frosst Centre for Therapeutic Research, Quebec, Canada) yves_leblanc@merck.com

Session D	(Sala Mizar)
	Chair: Professor Alba Chimirri (University of Messina, Italy)

1D-OC1	New Synthetic Concepts Toward Pyrrolizidines and Indolizidines
	M.V. Pilipecz, T.R. Varga, Z. Mucsi, P. Nemes, P. Scheiber (Szent István University, Budapest, Hungary) Nemes.Peter@aotk.szie.hu

1D-OC2	Porphyrin Arrays for Light Harvesting Devices
	F. Lodato, D.L Officer (Massey University, Palmerston North, New Zealand) F.Lodato@massey.ac.nz

1D-OC3	Synthesis and Redox Behaviour of New Singly and Doubly Bridged Bis-BenzoTTF
	L.Boudiba, A.K. Gouasmia, J.M.Fabre (Université de Tébessa, Algeria) lboudiba@hotmail.com

1D-OC4	Chemoenzymatic Synthesis of Optically Active Substituted Pyrrolidin-2-ones and Pyrrolidines
	F. Felluga, V. Gombac, G. Pitacco, E. Valentin (Università di Trieste, Italy) felluga@dsch.univ.trieste.it

1D-OC5	Functionalizations of the C₃ Side Chain of Densely Substituted Azetidin-2-ones
	F. Benfatti, G. Cardillo, L. Gentilucci, R. Perciaccante, A. Tolomelli (University of Bologna, Italy) alessandra.tolomelli@unibo.it

1D-OC6	Design, Synthesis, and Application of Pyrrolizidine Dipeptide Isosteres
	F.M. Cordero, M. Salvati, F. Pisaneschi, F. Machetti, A.M. Papini, A. Brandi (Università degli Studi di Firenze, Italy) franca.cordero@unifi.it

1D-OC7	Synthesis of Heterocyclic Amino Acid Derivatives by Palladium-Catalyzed Borylation and Suzuki Coupling (BSC) and Metal-Assisted C-N Intramolecular Cyclization
	M.R.P. Queiroz, A.S. Abreu, P.M.T. Ferreira (Universidade do Minho, Braga, Portugal) mjrpq@quimica.uminho.pt

1D-OC8	Syntheses and Oxidative Transformations of Styrylchromones
	T. Patonay, A.M.S. Silva, A. Kiss-Szikszai, A. Vasas, V.L.M. Silva, D.C.G.A. Pinto, J.A.S. Cavaleiro (University of Debrecen, Hungary) tpatonay@puma.unideb.hu

1D-OC9	The Synthesis of Important Pharmaceutical Building Blocks by Palladium-Catalyzed Coupling Reaction: Access to various functionalized Arylhydrazines Salts and related Azaheterocycles
	C.C. Mauger, G.A. Mignani (Centre de Recherches de Lyon, France) gerard.mignani@eu.rhodia.com

MONDAY, AUGUST 1		POSTERS SESSION 1-PO1 ÷ 1-PO92

17:15 - 18:45
1-PO1	New Synthetic Procedure for the Synthesis of Chiral Lactams
	A.U. Buranov, K.M. Shakhidoyatov (Department of Organic Synthesis, Tashkent, Uzbekistan) buranov71@yahoo.com

1-PO2	New Technique for Synthesizing and Separating Process of 5-Chloro-2, 3-difluoropyridine as an Intermediate of Herbicides
	A. Ahmadi, T. Yousefifard (Islamic Azad University, Karaj, Iran) abbas_ahmady_3957@yahoo.com

1-PO3	A Convenient Route *to Diverse Heterocycles via* 3-Halogeno-4-methoxybenzynes**
	K. Yoon, K. Kim (Seoul National University, South Korea) kkim@plaza.snu.ac.kr

1-PO4	Reaction of Azaenolates Derived from α-Chloroketimines with N-Tosylimines: Diastereoselective Synthesis of 2-Imidoylaziridines
	S. Mangelinckx, N. Giubellina, J. Jacobs, N. De Kimpe (Gent University, Belgium) norbert.dekimpe@UGent.be

1-PO5	Synthesis and Molecular Rearrangement of some 3-Ureidoquinoline-2,4-diones and Imidazo[4,5-c]quinoline-2,4-diones
	A. Klasek, A. Lycka, M. Holcapek (Tomas Bata University, Czech Republic) Klasek@ft.utb.cz

1-PO6	Synthetic Study on 28-Deacetylbelamcandal
	M. Inui, K. Henmi, A. Nakazaki, S. Kobayashi (Tokyo University of Science, Japan) j3104702@ed.noda.tus.ac.jp

1-PO7	Synthetic Study on Norzoanthamine
	Y. Murata, M. Shimanuki, A. Nakazaki, S. Kobayashi (Tokyo University of Science, Japan) j3104702@ed.noda.tus.ac.jp

1-PO8	Stereoselective Synthesis of Functionalized Spiro[4.5]decanes by Claisen Rearrangement of Bicyclic Dihydropyranes
	A. Nakazaki, H. Miyamoto, K. Henmi, S. Kobayashi (Tokyo University of Science, Japan) nakazaki@rs.noda.tus.ac.jp

1-PO9	A Facile Synthesis of 1-Substituted Isoindolines by Trifluoroacetic Acid-catalyzed Pictet-Spengler Reaction
	Y. Horiguchi, M. Kitabatake, T. Saitoh, Y. Hanzawa.(Showa Pharmaceutical University, Tokyo, Japan) horiguti@ac.shoyaku.ac.jp

1-PO10	Palladium-Catalyzed Deuteration of Heterocyclic Compounds in Deuterium Oxide
	K. Hirota, H. Esaki, F. Aoki, T. Maegawa, H. Sajiki (Gifu Pharmaceutical University,, Japan) hirota@gifu-pu.ac.jp

1-PO11	Stereoselective Synthesis of Cephalotaxine and Cylindricine Skeletons Using Radical Cascade Involving 5-Endo-trig Cyclization
	T. Taniguchi, A. Ishita, M. Uchiyama, O. Tamura, H. Ishibashi (Kanazawa University, Japan) isibasi@p.kanazawa-u.ac.jp

1-PO12	Effect of Oxygen Substituents on the Regioselectivity of Pd-Assisted Aryl-aryl Coupling Reaction of Benzanilides
	T. Sato, Y. Kawata, C. Nagura, T. Miyagoe, T. Harayama (Okayama University, Japan) harayama@pharm.okayama-u.ac.jp

1-PO13	Indolylcuprate as Highly Efficient Intermediate for Construction of 2,3-Disubstituted Indoles
	M. Sato, R. Uemura, M. Ishikura (Health Sciences University of Hokkaido, Japan) ishikura@hoku-iryo-u.ac.jp

1-PO14	Photochemical Reactions of N-(α-Haloacyl)enaminones and Related Compounds
	T. Nishio, M. Tabata, H. Yamasaki, H. Kuga (University of Tsukuba, Ibaraki, Japan) ishio@kankyo.envr.tsukuba.ac.jp

1-PO15	Synthesis and Fluorescence of 6-(4-Dimethylaminophenyl)-and 6-[2-(4-Aminophenyl)vinyl]-4-methylthio-2-oxo-2H-pyran-2-carbonitriles in Solution and in Solid States
	N. Mizuyama, Y. Tominaga, Y. Murakami, Y. Shigemitsu (Nagasaki University, Japan) naoko-mz@clnc.uoeh-u.ac.jp

1-PO16	Asymmetric Synthesis of (-)-Dihydrocuscohygrine using Diastereoselective Addition of Grignard Reagent to Bisoxazolidine
	T. Yamauchi, K. Higashiyama (Hoshi University School of Pharmacy and Pharmaceutical Sciences, Tokyo, Japan) kimio@hoshi.ac.jp

1-PO17	A New Methodology of Intramolecular Hetero Diels-Alder Reaction for Construction of Fused Heterocycles with Nitro Olefins as Heterodienes
	E. Wada, M. Yoshinaga (Shimane University, Matsue, Japan) wadae@riko.shimane-u.ac.jp

1-PO18	An Efficient and Safe Procedure for the Large Scale Pd-catalyzed Hydrazonation of Aromatic Chlorides: Access to Various Functionalized Arylhydrazines Salts and Related Azaheterocycles
	C.C. Mauger, G.A. Mignani (Rhodia Recherches, Lyon, France) gerard.mignani@eu.rhodia.com

1-PO19	Organogel Formation by Self-assembly of Urea Derivatives with Pyridyl Group
	S. Arai, S. Kusuda, I. Yoshihama, K. Kitahara, S. Oishi, T. Takemura (Tokyo Medical University, Japan) s-arai@tokyo-med.ac.jp

1-PO20	Microbial Baeyer-Villiger Oxidation of Cycloketones
	M.D. Mihovilovic, R. Snajdrova (Vienna University of Technology, Austria.) radka@ioc.tuwien.ac.at

1-PO21	Aza- and Oxabicyclo[5.n.0] Ring Systems (n = 2, 3) from Allenynes
	C. Mukai, F. Inagaki, K. Yoshitani, Y. Hara, S. Kitagaki (Kanazawa University, Japan) cmukai@kenroku.kanazawa-u.ac.jp

1-PO22	Synthesis and Reduction of Imidazopyridines (an Approach to Imidazopiperidines)
	D. Ellis (Pfizer Global Research and Development, Kent, England) David.Ellis@pfizer.com

1-PO23	Regioselective Synthesis of Benzo[f]phthalazinone Isomers
	P. Tapolcsányi, B.U.W. Maes, K. Monsieurs, G. Neumajer, P. Mátyus (Semmelweis University, Budapest, Hungary) tpal@szerves.sote.hu

1-PO24	Double Nucleophilic Reaction to the Imidazole Nucleus
	I. Kawasaki, T. Osaki, K. Sato, K. Itakura, M. Yamashita, S. Ohta (Kyoto Pharmaceutical University, Japan) sohta@mb.kyoto-phu.ac.jp

1-PO25	A recyclable Catalyst for Asymmetric Transfer Hydrogenation with a Formic Acid-triethylamine Mixture in Ionic Liquid
	I. Kawasaki, T. Tsuji, T. Yonezawa, M. Yamashita, S. Ohta, Y. Takemoto, H. Miyabe (Kyoto Pharmaceutical University, Japan) sohta@mb.kyoto-phu.ac.jp

1-PO26	Dinitrobutadienic Building-Blocks from the Ring Opening of 3,4‑Dinitrothiophene: New Perspectives
	L. Bianchi, C. Dell’Erba, M. Maccagno, G. Petrillo, E. Rizzato, F. Sancassan, E. Severi, M. Stenta, D. Spinelli, C. Tavani (Università di Genova, Italy) petrillo@chimica.unige.it

1-PO27	Synthesis of Thiirane 1-Imides and Their Ring-expansion to 1,2‑Thiazetidines
	Y. Sugihara, Y. Aoyama, R. Ohtsu, A. Kobiki, H. Okada, J. Nakayama (Saitama University, Japan) nakaj@post.saitama-u.ac.jp

1-PO28	Ring-Transformation of Selenopyrylium Salts 1. Preparation of Novel 1,3-Benzoselenazepines from 1-Benzoselenopyrylium Salts
	H. Sashida, S. Nakabayashi, H. Minamida (Hokuriku University, Kanazawa, Japan) 200m007@stu.hokuriku-u.ac.jp

1-PO29	Ring-Transformation of Selenopyrylium Salts 2. Preparation of 2,3‑Benzodiazepines from 2-Benzoselenopyrylium Salts
	H. Sashida, K. Ohyanagi (Hokuriku University, Kanazawa, Japan) h-sashida@hokuriku-u.ac.jp

1-PO30	Regioselective Ring Cleavage of 3-Methylene-1,5-benzodioxepanes
	M. Ishizaki, M. Hayashida, K. Nishitani, H. Hara (Josai International University, Japan) ishizaki@jiu.ac.jp

1-PO31	Photoreactions of 6-Azabicyclo[3.1.0]hexane Derivatives with Alkenes and Alkynes
	K. Ishii, M. Kido, S. Sugiyama, M. Noji (Meiji Pharmaceutical University, Tokyo, Japan) ishiikei@my-pharm.ac.jp

1-PO32	Selective Introduction of Carbon Nucleophiles into Heteroaromatic Compounds by the Hypervalent Iodine(III)-induced Oxidation Reactions
	T. Dohi, K. Morimoto, A. Maruyama, M. Yoshimura, H. Tohma, Y. Kita (Osaka University, Japan) kita@phs.osaka-u.ac.jp

1-PO33	Transformation of Cyclic Amines to ω-Amino Acids by Ruthenium Tetroxide Oxidation Using Single-Phase System
	M. Kaname, H. Mashige, N. Andou, S. Yoshifuji (Hokuriku University, Kanazawa, Japan) m-kaname@hokuriku-u.ac.jp

1-PO34	Metalloporphyrin Cr(TPP)Cl Catalyzed Claisen Rearrangement of Simple Aliphatic Allyl Vinyl Ethers and Its Unique Stereoselectivity
	T. Takanami, M. Hayashi, K. Suda (Meiji Pharmaceutical University, Tokyo, Japan) takanami@my-pharm.ac.jp

1-PO35	*Synthesis of New Ortho-functionalizedbenzophenone Derivatives, Key Intermediates for New Condensed Heterocyclic Compounds.*
	G. Lukács, M. Porcs-Makkay, G. Simig (Chemical Research Division, Budapest, Hungary) porcs@freemail.hu

1-PO36	One-pot Synthesis of Benzo[b]thiophene Ring System from Cycloaddition of Thiocoumarins and Mesoionic 1,3-Oxazolium-5-olates
	M. Cordaro, G. Grassi, F. Risitano, F. Foti (Università di Messina, Italy) ggrassi@isengard.unime.it

1-PO37	Efficient Syntheses of 5-Aminopyrimidin-4(3H)-ones
	D. Takahashi, Y. Honda, K. Izawa (AminoScience Laboratories, Kawasaki, Japan 210-8681) daisuke_takahashi@ajinomoto.com

1-PO38	Synthesis of Nitrogenous Heterocycles on the Base of Exo-3,4-diazatricyclo[5.2.1.0^2,6]decenes
	D.V. Petrov, V.A. Gorpinchenko, E.A. Shafikova, V.A. Dokichev, Yu.V. Tomilov (Ufa Research Center of the Russian Academy of Sciences, Russia) dokichev@anrb.ru

1-PO39	Synthesis of Spirooxazolines
	A. Horvat, B. Vercek (University of Ljubljana, Slovenia) *bojan.vercek@fkkt.uni-lj.si*

1-PO40	2,3-Dihydrooxazoles by One-pot Reaction of Nosyloxycarbamates with 2-Alkylidene 3-oxo Nitriles
	E. Burini, S. Fioravanti, A. Morreale, L. Pellacani, P.A. Tardella (Università degli Studi di Roma La Sapienza, Italy) stefania.fioravanti@uniroma1.it

1-PO41	Synthesis of Aziridinyl Modified Peptides
	S. Fioravanti, A. Morreale, L. Pellacani, P.A. Tardella (Università degli Studi di Roma La Sapienza, Italy) alberto.morreale@uniroma1.it

1-PO42	Novel Fluorescent 2,5-Diaryl-3,6-diphenyl-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione (DPP) Chromophores
	R.L. Riggs, C.J.H. Morton, A.M.Z. Slawin, D.M. Smith (University of St. Andrews, UK) rr9@st-andrews.ac.uk

1-PO43	Synthetic Studies Towards Huperzine A
	J. Ward, V. Caprio (University of Auckland, New Zealand) jm.ward@auckland.ac.nz

1-PO44	Formation and Electrophilic Reaction of a Novel Aromatic Azatropylium.
	K. Satake, C.E.J. Cordonier, Y. Kawamoto, Y. Kubota, H. Okamoto, M. Kimura (Okayama University, Japan) satake@cc.okayama-u.ac.jp

1-PO45	Solid-Phase Synthesis of 2-Aminothiazolines
	H. Jeon, T.H. Kim (Chonnam National University, Gwangju, South Korea) thkim@chonnam.ac.kr

1-PO46	Convenient Methods for Preparing Bicyclic Ring Systems Via Samarium(II)-induced Sequential Reactions and an Application to the Synthesis of Gibberellin A₁
	H. Nagaoka, I. Shinohara, A. Kishida (Meiji Pharmaceutical University, Tokyo, Japan) nagaoka@my-pharm.ac.jp

1-PO47	Stereoselective Synthesis of 2-Substituted Benzopyrans by Means of the Ring Fission of Benzopyrano-1,4-oxathianes
	Y. Hoshino, S. Hiromori, M. Sato, K. Honda, S. Inoue (Yokohama National University, Japan) yhoshino@ynu.ac.jp

1-PO48	*Cyclization via* An N-Acyliminium Ion Intermediate to Indolizidines Utilizing Halo Aldol-Type Reaction of α,β-Unsaturated Carbonyl Compounds by TiCl₄-Bu₄NI**
	Y. Koseki, H. Sato, A. Takeshita, T. Nagasaka (Tokyo University of Pharmacy & Life Science, Japan) nagasaka@ps.toyaku.ac.jp

1-PO49	Stereoselective Synthesis of Chiral 4-Substituted γ-Amino Acid Derivatives Precursors of Indolizidine Alkaloids
	M.C. Corvo, M.M.A. Pereira (Universidade Nova de Lisboa, Caparica, Portugal) mmm@dq.fct.unl.pt

1-PO50	Synthesis of Heterocycles from N-Alkenylamides Using ^tBuOCl-NaI System
	Y. Morino, S. Minakata, Y. Oderaotoshi, M. Komatsu (Osaka University, Japan) yomorino@chem.eng.osaka-u.ac.jp

1-PO51	Ortho-Lithiated Aryloxiranes in the Stereoselective Synthesis of Phthalanes
	V. Capriati, S. Florio, R. Luisi, F.M. Perna, A. Salomone (Università degli Studi di Bari, Italy) antoniosalomone@libero.it

1-PO52	Nitroacids Methyl Esters in the Synthesis of Piperidine and Hexahydropyrimidine
	R.R. Shakirov, N.Z. Baybulatova, V.A. Dokichev, Yu.V. Tomilov (Ufa Scientific Center of the Russian Academy of Sciences, Russia) dokichev@anrb.ru

1-PO53	Ring Closing Metathesis approach to Functionalized Indazolidines
	A. Gopalsamy, M. Shi, J. Casey, J. Ellingboe (Wyeth Research, NY, USA) gopalsa@wyeth.com

1-PO54	Regioselective Conversion of Epoxides into Chlorohydrins using Chlorotitanium(IV) Reagents
	K. Nishitani, K. Shinyama, K. Yamakawa, H. Hara (Tokyo University of Science, Chiba, Japan) nisitanir@rs.noda.tus.ac.jp

1-PO55	Applications of Capillary Electrophoresis in the Monitoring of Synthesis of Heterocyclic Compounds
	M.A. Balboa, V.H. Abrego, B. Camacho, A. Jiménez, A. Pérez, A.Ma. Velázquez, L. Martìnez, L.A. Torres, G. Díaz, Ma.G. Nuñez, N. Tlapalamatl, R. Gazelem, R. González, A. Ramírez, I. Martínez, R. López-Castañares, E. Angeles (Universidad Nacional Autónoma de México, México) angeles@servidor.unam.mx.

1-PO56	One pot Synthesis of a New Heterocyclic Methylpiperidin, Methylmopholin and Methyltiomorpholin Phenols Derivatives
	M.A. Balboa, A.Ma. Velázquez, V.H.Abrego, B. Camacho, I. Menconi, L. Martìnez, L.A. Torres, G. Montes, G. Díaz, Ma.G. Nuñez Zárraga, N. Tlapalamatl, R. Gazelem, R. González, A. Ramírez, I. Martínez, R. López-Castañares, E. Angeles (Universidad Nacional Autónoma de México, México) angeles@servidor.unam.mx.

1-PO57	Fluorescent Heterocyclic Dye Systems for Visualization of Trace Evidence at Crime Scenes
	J.J. Krutak, B. Eckenrode, V. Cavett, G. Patonay, L. Strekowski, J.Salon, M. Say, M. Medou-Ovono (FBI Academy, Quantico USA) jkrutak@fbiacademy.edu

1-PO58	Electrosynthesis of Hantzsch 1,4-Dihydropyridines in Protic Media
	Lida Fotouhi (Alzahra University, Tehran, Iran) lida_fotouhi@yahoo.com

1-PO59	*Synthesis of Bis[1]benzothieno[2,3-c:3',2'-i]-1,10-phenanthroline via* Tandem Photocyclization to Generate the 1,10-Phenanthroline Moiety**
	T.M. Abu Elmaati, L.W. Castle (Idaho State University, Pocatello, USA)

1-PO60	A Novel Clathrate Host for Diaminoethanes
	K. Yamaguchi, Y. Yoshitake, K. Harano (Sojo University, Kumamoto, Japan) harano@gpo.kumamoto-u.ac.jp

1-PO61	Synthesis and Photochemical Reactions of 2,3-Distyrylfurans
	I. Škorić; M. Šindler-Kulyk (University of Zagreb, Croatia) iskoric@fkit.hr

1-PO62	Intramolecular 1,3-Dipolar Cycloadditions of the New Sydnone Derivatives
	K. Butkovic, Z. Marinic, M. Sindler-Kulyk (University of Zagreb, Croatia) butkovic@fkit.hr

1-PO63	Synthesis of 5-(Diethylphosphono)-1,3-thiazolidine Derivatives
	Y. Okada (Kinki University, Higashi-Hiroshima, Japan) okadasan@hiro.kindai.ac.jp

1-PO64	Synthesis and Reaction of Mesoionic 1,3-Oxazolium-4-olates, 1,3‑Oxazolium-5-olates, and 1,3-Thiazolium-4-thiolate Condensed Seven-membered Ring
	H. Nakano, I. Kamiya, A. Mizutani (Aichi University of Eduction, Japan) hnakano@auecc.aichi-edu.ac.jp

1-PO65	Synthesis of 2-Substituted Pyrroles from Allylamides
	A. Spaggiari, D. Vaccari, P. Davoli, G. Torre, F. Prati (Università di Modena e Reggio Emilia , Italy) prati.fabio@unimore.it

1-PO66	Study Reactivity of Unsaturated Pentafluorosulfanyl Derivatives as Dipolarophiles in 1,3-Dipolar Cycloaddition
	V.K. Brel (Russian Academy of Sciences, Moscow, Russia) brel@ipac.ac.ru

1-PO67	(5)-(2-Hydroxyphenyl)-5(3)-styrylpyrazoles: Synthesis and Diels-Alder Transformations
	V.L.M. Silva, A.M.S. Silva, D.C.G.A. Pinto, J.A.S. Cavaleiro, J. Elguero (University of Aveiro, Portugal) arturs@dq.ua.pt

1-PO68	Syntheses of New Xanthones Derivatives
	C.M.M. Santos, A.M.S. Silva, J.A.S. Cavaleiro (University of Aveiro, Portugal) clems@dq.ua.pt

1-PO69	Synthesis of New [60]Fulleropyrrolidine-glucose Conjugates
	R.F. Enes, A.C. Tomé, J.A.S. Cavaleiro (University of Aveiro, Portugal) rfenes@dq.ua.pt

1-PO70	Progress Toward an Efficient Synthesis of Bis(Phenylenedioxy) tetrathiafulvalene; a Modified Synthesis of Precursor Iminium Salt
	H.S. Kasmai, H. Li, D. Biswas Hamid, S. Kasmai; H. Li, D. Biswas (East Tennessee State University, Johnson City, USA) kasmai@etsu.edu

1-PO71	Red-Emitting Thienylbenzene Branched Dendrimers with Benzothiadiazole Core
	K.R.J. Thomas, T. Huang, J.T. Lin (Academia Sinica, Taipei, Taiwan) jtlin@chem.sinica.edu.tw

1-PO72	Synthesis of Pyrrole Derivatives via Cyclopropanation of Vinyl Ethers with Diazoketones
	M. Romero, B. Flores, J.M. Méndez (Universidad Nacional Autónoma de México, México) tey@servidor.unam.mx

1-PO73	5-Substituted-1,3,4-oxadiazol-2(3H)-ones in Synthesis of 1,2,4-Triazol-3(4H)-ones
	M. Jure, I. Ramina, M. Petersone, I. Potorocina (Riga Technical University, Latvia) mara@ktf.rtu.lv

1-PO74	A Versatile Multicomponent Approach Towards N-Heterocyclic Carbene Complexes
	R.S. Bon, N. Sprenkels, B. van Vliet, R.F. Schmitz, F.J.J. de Kanter, M.C. Jahnke, F.E. Hahn, M.B. Groen, R.V.A. Orru (Vrije Universtiteit Amsterdam, Netherlands) bon@few.vu.nl

1-PO75	Effect of Compact Bicyclic Phosphine Ligand SMAP in Palladium-catalyzed Decarboxylative Hydrogenolysis of Propargylic Formates: Regioselective Synthesis of Internal Allenes
	M. Sawamura, Y. Ohtsuka, Y. Yamauchi (Hokkaido University, Sapporo, Japan) sawamura@sci.hokudai.ac.jp

1-PO76	Safe Synthetic Equivalent of Nitromalonaldehyde
	Y. Nakaike, T. Ogihara, M. Tamura, N. Nishiwaki, M. Ariga (Osaka Kyoiku University, Japan) j049336@ex.osaka-kyoiku.ac.jp

1-PO77	Syntheses of Versatile 1-Methyl-2-quinolone Derivatives
	M. Asahara, M. Tamura, N. Nishiwaki, M. Ariga (Osaka Kyoiku University, Japan) nishi@cc.osaka-kyoiku.ac.jp

1-PO78	Synthesis of Polysubstituted Indoles by Iterative Use of the Aromatic Pummerer-Type Reaction
	N. Kawashita, K. Kakiguchi, Y. Wada, S. Akai, Y. Kita (Osaka University, Japan) kita@phs.osaka-u.ac.jp

1-PO79	Nitroalkylation Reactions of Paraconic Acid Derivatives
	C. Forzato, P. Nitti, G. Pitacco, E. Valentin (Università di Trieste, Italy) nitti@dsch.univ.trieste.it

1-PO80	Tandem Cleavage of Azepinoindoles Under the Action of Activated Alkynes – A Novel Synthesis of Azoninoindoles
	V.A. Varlamov, S.V. Akbulatov, L.G. Voskressensky, T.N. Borisova (Russian Peoples Friendship University, Moscow, Russia) avarlamov@sci.pfu.edu.ru

1-PO81	Studies Towards the Synthesis of Novel Pyrrolobenzodiazocine Ring System
	N. M. Karousis, K. P. Koriatopoulou, G. A. Tsakonas, K. D. Papavasileiou, T. D. Tzima, V. S. Melissas, A. Geronikaki, G. Varvounis (University of Ioannina, Greece) nkarousis@yahoo.com

1-PO82	The Reactivity of 2-Oxoimidazoles: Preliminary Studies
	A. Dias, M. Zaki, M.F. Proença (Universidade do Minho, Braga, Portugal) fproenca@quimica.uminho.pt

1-PO83	New Synthesis of Indolo[b]pyridines via Iminophosphorane
	C. Bonini, G. Lorusso, M. Funicello, P. Spagnolo (Università della Basilicata, Potenza, Italy) funicello@unibas.it

1-PO84	New Mannich-Werner Bases of Substituted Chroman-4-ones by a Four-components-domino-reaction (4CDR) of some Halogenated 2-Bromo-2’-hydroxyacetophenones
	L.F.Tietze, A. Cascaval (University of Iasi, Romania) cascaval@uaic.ro

1-PO85	New Mannich-Werner Bases of Halogenated Chroman-4-ones by a Three-components-domino-reaction (3CDR) of some Halogenated 2’-Hydroxypropiophenones
	L.F.Tietze, A. Cascaval (University of Iasi, Romania) cascaval@uaic.ro

1-PO86	Bis Mannich-Werner Bases of 6,8-Diiodocroman-4-one by a Three-components-domino-reaction (3CDR) of 2’-Hydroxy-3’,5’-diiodo-acetophenone
	L.F.Tietze, A. Cascaval (University of Iasi, Romania) cascaval@uaic.ro

1-PO87	Effect of Linear 5-Alkyl Substituents on the Rearrangement Rate of the Z-Phenylhydrazones of some 5-Alkyl-3-benzoyl-1,2,4-oxadiazoles
	S. Guernelli, P. Lo Meo, E. Mezzana, S. Moranti, R. Noto, D. Spinelli (Università degli Studi di Bologna, Italy) guernel@ms.fci.unibo.it

1-PO88	Synthesis of Ferrocenyl-1-(4-pyridylmethyl)- and Ferrocenyl-1-[2-hydroxy-1,2-bis(4-pyridyl)ethyl]pyrazoles
	E.I. Klimova, E.A. Vázquez López, J.M. Méndez Stivalet (Universidad Nacional Autónoma de México, México) klimova@servidor.unam.mx

1-PO89	Application of Vinylogous Mannich Adducts to a Simple Stereocontrolled Synthesis of Tetrasubstituted Piperidines
	J.M. Aurrecoechea, J.M. Gorgojo, C. Saornil, R. Suero (Universidad del País Vasco, Bilbao, Spain) qopaufem@lg.ehu.es

1-PO90	Reactions of Aromatic Nitroso Compounds with a Chemical Model of Thiamine
	M.M.B. Marques, L.P. Ferreira, P.M.C. Glória, A.M. Lobo(Universidade Nova de Lisboa, Portugal) mmbmarques@dq.fct.unl.pt

1-PO91	Novel Synthesis of Substituted Imidazoles by Thiocarbohydrazide
	N. Nami, M.M. Heravi, H.A. Oskooie, R. Hekmatshoar (Azad Islamic University, Ghaemshahr Branch, Iran) navabehnami@yahoo.com

1-PO92	T-Reactions in Stereoselective Synthesis of Benzoanagyrine Derivatives
	V.G. Kartsev, K.A. Krasnov (InterBioScreen Ltd., Russia), screen@ibscreen.chg.ru

TUESDAY, AUGUST 2				ORAL CONTRIBUTIONS

15:00 – 17:00
Session A	(Sala Orsa)
	Chair: Professor Ennio Valentin (University of Trieste, Italy)

2A-OC10	Stereoselective Baeyer-Villiger Oxidation by Recombinant Whole-Cells
	M.D. Mihovilovic (Vienna University of Technology, Austria) mmihovil@pop.tuwien.ac.at

2A-OC11	New Bio-reducing Agents: Application to Syntheses of Enantiopure Hydroxy-β-Lactams
	M. Kayser, Y. Yang, M. Drolet (University of New Brunswick, Canada) kayser@unbsj.ca

2A-OC12	Development of Novel Chiral Ligands Bearing Spiro Skeleton
	P. Koranne, T. Tsujihara, T. Shinohara, S. Takizawa, H. Sasai
	(Osaka University, Japan) sasai@sanken.osaka-u.ac.jp

2A-OC13	Highly Stereoselective and Stereospecific Epoxidation of 2‑Phospholenes with Sodium Peroxide or Hydrogen Peroxide and Preparation of N-glycosides of Phospha Sugars
	M. Yamashita, K.R. Valluru, H. Totsuka, H. Buchammagari, T. Niimi, M. Takahashi, T. Oshikawa (Shizuoka University, Japan) tcmyama@ipc.shizuoka.ac.jp

2A-OC14	Solution and Solid-Phase Generation of Multifunctionalized 2-Amino-6-H-1,3-Thiazine Libraries
	G.A. Strohmeier, C.O. Kappe (University of Graz, Austria) oliver.kappe@uni-graz.at

2A-OC15	Evidence for Conformational Control in the 1,1'-Bis(1,2,3,4-tetrahydroisoquinoline) Ligand System
	B.H.K. Chan, J.B. Harper, M.W. Jones, R.W. Read (University of New South Wales, Sydney, Australia) r.read@unsw.edu.au

2A-OC16	Synthesis and Development of an HIV-1 Integrase Inhibitor of Clinical Interest
	R. Angelaud, P. Maligres, J. Lee, Y.-L. Zhong, D. Steinhuebel, M. Palucki, D. Askin (Merck Research Laboratories, NJ, USA) dave_askin@merck.com

2A-OC17	Novel Heterocyclic Hydroperoxides as Potential Antimalaria Compounds by Hydroperoxide Rearrangement
	H.-J. Hamann, A. Wlosnewski, R. Uebel, J. Liebscher (Humboldt-Universität Berlin, Germany) liebscher@chemie.hu-berlin.de

Session B	(Sala Nova)
	Chair: Professor Gaetano Tomaselli (University of Catania, Italy)

2B-OC10	Synthesis of Marine Natural Products and Related Compounds using Combinatorial Strategies
	D. Pla, A. Marchante, C.A. Olsen, N. Parera, F. Albericio, M. Álvarez (University of Barcelona, Spain) malvarez@pcb.ub.es

2B-OC11	Amino Acid Models of the Active Site of Cytochrome c Oxidase: Synthesis and Biophysical Studies with Biological Implications
	J.P. Konopelski, K.N. White, Y.R. Landaverry, N. Praveen, Ó. Einarsdóttir, I. Szundi, I. Sen, A. Patra, B.A. Barry, I. Vassiliev (University of California, Santa Cruz, CA) joek@chemistry.ucsc.edu

2B-OC12	New Series of Tri-Substituted Triazoles and Imidazoles as Potent Non-Nucleoside Inhibitors of the HIV Reverse Transcriptase
	J.-L. Girardet, Z. Zhang, M. de la Rosa, H.W. Kim, E. Gunic, C.Jenket, W. Xu, J.H. Shim, S. Nilar, N. Yao, R. Hamatake, S. Lang, Z. Hong (Valeant Pharmaceuticals International, R&D Drug Discovery, CA USA) jlgirardet@valeant.com

2B-OC13	The Annelated Quinolizinium Ion as a Structural Motif for New DNA-photocleavaging Agents
	G. Viola, A. Faccio, D. Vedaldi_,H. Ihmels, D. Otto_,F. Dall’Acqua (University of Padova, Italy) francesco.dallacqua@unipd.it

2B-OC14	Arylthioindoles, Potent Inhibitors of Tubulin Polymerization
	G. De Martino, G. La Regina, A. Coluccia,M.C. Edler, M.C. Barbera, A. Brancale, E. Wilcox, E. Hamel, M. Artico, R. Silvestri (Università degli Studi di Roma La Sapienza, Italy) gabriella.demartino@uniroma1.it

2B-OC15	Bioactive Iminium Alkaloids from Marine Invertebrates
	D. Uemura (Nagoya University, Japan) uemura@chem3.chem.nagoya-u.ac.jp

2B-OC16	Synthesis and Properties of 4-Aminosubstituted-1H-benzo[1,4] diazepine-2,3,5-triones
	D. Geffken, M.A. Köllner (University of Hamburg, Germany) geffken@chemie.uni-hamburg.de

2B-OC17	Synthesis of Novel Diazirines Useful for the Selective Labelling and Characterisation of Enzymes
	V.-L. Truong, M.-A. Joly, P.J. Roy, S. Roy, J.Y. Gauthier (Merck Frosst Center for Therapeutic Research, Québec, Canada) jacques-yves_gauthier@merck.com

Session C	(Sala Orione)
	Chair: Professor Giovanni Petrillo (University of Genova, Italy)

2C-OC10	Diastereo and Enantio-selective Synthesis of Homocarbocyclic-2’-oxo-3’-azanucleosides
	U. Chiacchio, A. Corsaro, D. Iannazzo, A. Piperno, V. Pistarà, A. Rescifina, G. Romeo, R. Romeo, M.G. Saita (Università di Catania, Italy) mgsaita@tiscalinet.it

2C-OC11	One-pot Copper(I)-catalyzed Synthesis of 3,5-Disubstituted Isoxazoles
	T.V. Hansen, P. Wu, V.V. Fokin,K.B. Sharpless (University of Oslo, Norway) t.v.hansen@farmasi.uio.no

2C-OC12	Progress Toward the Synthesis of Halichlorine and Pinnaic Acid
	K. Takasu, T. Matsushita, H. Ohsato, M. Ihara (Tohoku University, Japan) kay-t@mail.pharm.tohoku.ac.jp

2C-OC13	Synthetic Studies toward (–)-Tetrodotoxin
	M. Isomura, S. Kikuchi, T. Itoh, S. Yokoshima, T. Fukuyama (University of Tokyo, Japan) yokosima@mol.f.u-tokyo.ac.jp

2C-OC14	The Synthesis of New Heterohelicenes
	F.M. McMillan, H. McNab (University of Edinburgh, UK) f.m.mcmillan@sms.ed.ac.uk

2C-OC15	Iminopropadienones, R-N=C=C=C=O, in Heterocyclic Synthesis
	C. Wentrup, M. Shtaiwi, R.N. Veedu, D. Kvaskoff (University of Queensland, Brisbane, Australia) wentrup@uq.edu.au

2C-OC16	Synthesis of Heterocyclic Derivatives by Cu- or Pd-catalyzed Heteroannulation Reactions
	B. Gabriele, G. Salerno, A. Fazio, R. Mancuso, P. Plastina, L. Veltri (Università della Calabria, Cosenza, Italy) b.gabriele@unical.it

2C-OC17	Synthesis of Thiazolyl-Thiazoles via Pd-Catalyzed Cross Coupling Reactions – First Synthesis of Thiazoleboronic Esters
	M. Schnürch, P. Stanetty (Vienna University of Technology, Austria) mschnuerch@ioc.tuwien.ac.at

Session D	(Sala Mizar) Chair: Maurizio D’Auria (University of Basilicata, Italy)

2D-OC10	Thiazolyl and Benzothiazolyl-N-substituted Amines as Possible Non-steroidal Antiinflammatory Agents
	A. Geronikaki, D. Hadjipavlou-Litina, Ch. Papadopoulou, Ch. Camoutsis (Aristotelian University of Thessaloniki, Greece) geronik@pharm.auth.gr

2D-OC11	Asymmetric Syntheses Pharmaceutically Interesting Piperidines and Related Alkaloids
	L.-X. Liu, B.-G. Wei, J.-F. Zheng, P.-Q. Huang (Xiamen University, China) pqhuang@xmu.edu.cn

2D-OC12	The reaction of Substituted Uracils with Ethylene as a General Route to Cyclobutane β-Aminoacids
	D.J. Aitken, S. Faure, C. Gauzy, E. Pereira, B. Saby (Université Blaise Pascal Clermont-Ferrand II, France) aitken@chimie.univ-bpclermont.fr

2D-OC13	DNA Binding and Antiproliferative Effect of 2-(5,6,7,8-Tetrahydro-5,5,8,8-Tetramethyl-2-naphthyl)-5-Benzimidazole Derivatives
	E. Buyukbingol, Z. Ates-Alagoz, K.A. Piskin (Ankara University, Turkey) erdem@pharmacy.ankara.edu.tr

2D-OC14	Constrained Tetrahydroimidazopyrimidine Derivatives as Corticotropin-Releasing Factor Type 1 Receptor (CRF 1 R) Antagonists
	V. Vrudhula, B. Dasgupta, D. Zuev, K. Burris, S. Pin, L. Balanda, K. Browman, T. Fiedler, L. Fung, J. Alberts, C. Dangler, F. Moulin, J. Megill, B. Andrews, R. Macci, J. Zhang, G. Dubowchik (Bristol-Myers Squibb Pharmaceutical Research Institute, Wallingford, USA) vivekananda.vrudhula@bms.com

2D-OC15	The Development of Bisphosphonates for Therapeutic Uses. Bisphosphonate Structure-activity Consideration
	W.M. Abdou (National Research Centre, Cairo, Egypt) wabdou@intouch.com

2D-OC16	Unique Antiviral Activity of Dioxolane-thymine Against Drug Resistant Mutants: Anti-HIV Activity, Resistant Profile and Mechanism
	C.K. Chu, V. Yadav, R.F. Schinazi (University of Georgia, Athens, USA) dchu@rx.uga.edu

2D-OC17	Synthesis of Peptidomimetic Analogues of Echinocandins
	C. Ma, S. Takeda, M. Daneshtalab (Memorial University of Newfoundland, Canada) mohsen@pharm.mun.ca

TUESDAY, AUGUST 2					POSTERS SESSION 2-PO1 ÷ 2-PO94

17:00 - 18:30

2-PO1	Synthesis of Novel 3-Methyl-1-oxo-1,3,4,6,11,11a-hexahydro-2H-pyrazino[1,2-b]isoquinoline-3-carboxamides. New Four-component Ugi Reaction
	A.P. Ilyn, A.S. Trifilenkov,D.I. Kovrigin, M.V. Yudin, I.A. Okun, S.E. Tkachenko, A.V. Ivachtchenko (ChemDiv, Inc., San Diego, USA) av@chemdiv.com

2-PO2	Synthesis of Novel Derivatives of 3,4-Dihydropyrrolo[1,2-a]pyrazin-1(2H)-one using a New Four-component Ugi Reaction
	A.P. Ilyn,J.A. Kuzovkova, A.M. Shkirando, D.I. Kovrigin, I.A. Okun, S.E. Tkachenko, A.V. Ivachtchenko (ChemDiv, Inc., San Diego, USA) av@chemdiv.com

2-PO3	Synthesis and Selective Decarboxylation of 6-(Morpholine-4-sulfonyl)-quinoline-2,3,4-tricarboxylic Acid
	D.V. Kravchenko, Y.A. Kuzovkova, V.V. Kysil, S.E. Tkachenko, S.Maliarchouk, I.M. Okun, A.V. Ivachtchenko (ChemDiv, Inc., San Diego, USA) av@chemdiv.com

2-PO4	Synthesis and Biological Activity of 4-Oxo-1,4,5,6-tetra-hydropyrazolo[4,3-f]pyrrolo[1,2-a][1,4]diazepine-6-carboxamides
	S.E. Tkachenko,A.P. Ilyn, A.S. Trifilenkov, J.A. Kuzovkova, S.A. Kutepov, A.V. Nikitin, I.A. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO5	Synthesis and Biological Activity of 6,7-Dihydrofuro- and 6,7‑Dihydrothieno[2',3':4,5]pyrrolo[1,2-a]pyrazin-8(5H)-ones
	S.E. Tkachenko, A.P. Ilyin, V.V. Kobak, I.G. Dmitrieva, Y.N. Peregudova, V.A. Kustova,Y.S. Mishunina, I.M. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO6	Synthesis and Biological Activity of Novel 4-Oxo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-6-carboxamides
	S.E. Tkachenko, A.P. Ilyn, A.S. Trifilenkov, S.A. Tsirulnikov, I.D. Kurashvily, I.M. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO7	Synthesis and Anticancer Activity of 8-Oxo-5,6,7,8-tetrahydro-imidazo[1,5-a]pyrazine-1-carboxamides
	A.P. Ilyn,A.S. Trifilenkov, I.M. Okun, S.E. Tkachenko, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO8	Synthesis and Biological Activity of 1-Oxo-1,2,3,4-tetrahydro-benzo[4,5]imidazo[1,2-a]pyrazine-3-carboxamides
	A.P. Ilyn, A.S. Trifilenkov, G.A. Sviridov, Y.A. Kuzovkova, I.M. Okun, S.E. Tkachenko, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO9	Synthesis and Biological Activity of Novel 6-oxo-5,6-dihydro-4H-pyrrolo[1,2-a][1,4]benzodiazepine-4-carboxamides
	A.P. Ilyn, J.A. Kuzovkova, S.A. Kutepov, A.V. Nikitin, Ilya M. Okun, Sergey E. Tkachenko, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO10	Derivatives of 2-(2-Acetyloxyethyl)-4-mercapto-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones as Potent Caspase-3 Inhibitors
	D.V. Kravchenko, Y.A. Kuzovkova, V.V. Kysil, S.E. Tkachenko, S. Maliarchouk, I.M. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO11	Synthesis and Biological Activity of 6-Oxo-5,6,7,8,9,10-hexahydro-4H-[1]benzothieno[3,2-f]pyrrolo[1,2-a][1,4]diazepine-4-carboxamides
	A.P. Ilyn, J.A. Kuzovkova, S.A. Kutepov, A.V. Nikitin, I.M. Okun, Sergey E. Tkachenko, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO12	Synthesis and SAR of 2-Substituted 4-Methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones as Potent Caspase-3 Inhibitors
	D.V. Kravchenko, V.V. Kysil, Sergey E. Tkachenko,S. Maliarchouk, I.M. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO13	Synthesis of 8-Sulfonyl-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinolines as Potent Nonpeptide Caspase-3 Inhibitors
	D.V. Kravchenko, V.V. Kysil, S.E. Tkachenko, S. Maliarchouk, I.M. Okun, A.V. Ivachtchenko (Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO14	Synthesis of Substituted 2-(2-Hydroxyethyl)-1,3-dioxo-2,3-dihydro-1H-pyrrolo[3,4-c]quinoline-8-sulfonic Acid Amides as Potent Caspase-3 Inhibitors
	D.V. Kravchenko, Y.A. Kuzovkova, V.V. Kysil, S.E. Tkachenko, S.Maliarchouk, I.M. Okun, A.V. Ivachtchenko(Chemical Diversity Research Institute, Moscow, Russia) api@chemdiv.com

2-PO15	Design and Synthesis of 3-Hydroxy-4,9-Dihydro-isothiazolo[5,4-b] quinoline-4-one Derivatives as Potential Topo-II Inhibitors and Antineoplastic Agents
	Z. Amoozgar, M. Daneshtalab (Memorial University of Newfoundland, Canada, USA) Mohsen@pharm.mun.ca

2-PO16	Syntheses of Substituted 4-(3-Indolyl)quinazolines, a New Class of EGFR-Tyrosinkinase Inhibitors
	A. Lüth, W. Löwe, M. Weber, P. Luger (Freie University, Berlin, Germany) AnjaLueth@aol.com

2-PO17	Synthesis and Biological Evaluation of Amidine Analogs of Melphalan
	A. Bielawska, K. Bielawski, W. Miltyk, T. Anchim, S. Wołczyński (University of Białystok, Poland) kbiel@amb.edu.pl

2-PO18	Synthesis, DNA Binding, Topoisomerase Inhibition and Cytotoxic Properties of 2-Chloroethylnitrosourea Derivatives of Hoechst 33258
	K. Bielawski, A. Bielawska, T. Anchim, S. Wołczyński (University of Białystok, Poland) kbiel@amb.edu.pl

2-PO19	Synthesis and Reaction of N-Sulfenylbenzimidazoles: Efficient Sulfenylating Reagents
	M. Shimizu, H. Fukazawa, Y. Abe (National Institute of Advanced Industrial Science and Technology, Japan) m.shimizu@aist.go.jp

2-PO20	Development of a New Antiviral Agent: Synthesis and Biological Evaluation of Furan-fused Tetracyclic Compounds
	K. Sasaki, Y. Matsuya, H. Ochiai, H. Remoto (Toyama Medical and Pharmaceutical University, Japan) matsuya@ms.toyama-mpu.ac.jp

2-PO21	Diversity-oriented Synthesis of Macrosphelides and Relating Compounds
	Y. Matsuya, T. Kawaguchi, K. Ishihara, N. Funamori, H. Nemoto (Toyama Medical and Pharmaceutical University, Japan) matsuya@ms.toyama-mpu.ac.jp

2-PO22	Synthesis of the New Furo[3,2-h]isoquinoline Alkaloid, TMC-120B from Aspergillus Ustus
	T. Kumemura, T. Choshi, J. Yukawa, A. Hirose, M. Fujii, J. Nobuhiro, S. Hibino (Fukuyama University, Hiroshima, Japan) hibino@fupharm.fukuyama-u.ac.jp

2-PO23	A Synthesis of Novel Indolo[3,2-j]phenanthridine Alkaloid, Calothrithin B
	S. Hibino, S. Tohyama, K. Matsumoto, K. Ikegawa, A. Yamabuki, J. Nobuhiro, C. Tominari (Fukuyama University, Hiroshima, Japan) hibino@fupharm.fukuyama-u.ac.jp

2-PO24	Lipase-catalyzed Asymmetric Synthesis of Chiral 6-Desprenylcarquinostatin A
	T. Choshi, Y. Uchida, Y. Kubota, K. Ikawa, T. Nakayama, J. Nobuhiro, M. Takeshita, S. Hibino (Fukuyama University, Hiroshima, Japan) choshi@fupharm.fukuyama-u.ac.jp

2-PO25	Synthesis of 2-Amino-6-(arylaminomethyl)thieno[2,3-d]pyrimidin-4(3H)-ones as Potential Antifolates
	S. Tumkevicius, M. Dailide, V. Navickas (Vilnius University, Lithuania) sigitas.tumkevicius@chf.vu.lt

2-PO26	Synthesis and Evaluation as Antimalarial Agents of New Bis(5-nitroindazole) Derivatives
	C. Ochoa, V.J. Arán, M. Martins, R.N. García, J.J. Nogal-Ruiz, A.R. Martínez-Fernández (University of Madrid, Spain) carmela@iqm.csic.es

2-PO27	Synthesis and Evaluation of 2-Iminodihydropyrimidine Derivatives as Analgesic and Anti-Inflammatory Compounds
	A. Suay, T. Olivar,M. E. González-Rosende,E. Castillo, A. Fuster, J. Sepúlveda-Arques (CardenalHerrera-CEU University, Valencia, Spain) eugenia@uch.ceu.es

2-PO28	Synthetic Studies Towards the Rubromycins
	K.Y. Tsang, M.A. Brimble (University of Auckland, New Zealand) k.tsang@auckland.ac.nz

2-PO29	Use of Allylbroration for the Enantioselective Synthesis of Pyranonaphthoquinone Antibiotics
	M.A. Brimble, P. Bachu (University of Auckland, New Zealand) Bachu_p@yahoo.com

2-PO30	Studies Towards the Enantioselective Synthesis of Methyllycaconitine
	S. Carley, C. Brocke, M. Brimble (University of Auckland, New Zealand) scar075@ec.auckland.ac.nz

2-PO31	Studies Toward the Synthesis of Moroidin and Stephanotic Acid
	D. Bentley, C.J. Moody (University of Exeter, UK) D.J.Bentley@ex.ac.uk

2-PO32	Rational Drug Design of DNA Cross-linking Agents
	S. Alcaro, A. Artese, R.S. Coleman, A. Gallelli, F. Ortuso, R. Pasceri, A. Procopio (University of Catanzaro, Italy) alcaro@unicz.it

2-PO33	Synthesis of Novel Ring Constrained Thiazole-pyrimidine CDK Inhibitors
	N.A. McIntyre, N.J. Westwood, M. Thomas, G. Kontopidis, C. McInnes, S. Wang, P.M. Fischer (University of St. Andrews, UK) nam11@st-andrews.ac.uk

2-PO34	NOvel Heterocyclic Systems of Pyridazines
	N.G. Kandile, M.I. Mohamed, H.T. Zaky, H.M. Mohamed (Faculty of Women Ain Shams University, Heliopolis Cairo, Egypt) nadiaghk@yahoo.com

2-PO35	Synthesis of Bromoindole Derivatives by Bromination of Dimethyl Indole-2,3-dicarboxylates
	Y. Miki, M. Umemoto, M. Nakamura (Kinki University, Higashi-Osaka, Japan) miki@phar.kindai.ac.jp

2-PO36	[1,8]-Naphthyridines: a New Class of GABA-A Receptor Benzodiazepine Binding Site Ligands
	A. Mitchinson, J.R. Atack, R.W. Carling, J.L. Castro, M.G.N. Russell, R.M. McKernan, R. Newman, E. Philipps, L.J. Street (Merck Sharp & Dohme Research Laboratories, Essex, UK) andrew_mitchinson@merck.com

2-PO37	Synthesis and Characterization of New Acridone Glucosides
	M.L. Fascio, N.B. D'Accorso, M. Docampo Palacios, R.F. Pellón (University of Buenos Aires, Argentina) norma@qo.fcen.uba.ar

2-PO38	Synthesis of Antifungical Compounds for Soya Cultures Preservation
	S. Barradas, M.I. Errea, N.B. D'Accorso (University of, Buenos Aires, Argentina) norma@qo.fcen.uba.ar

2-PO39	Synthesis and Antimalarial Activity of Benzothiazine S,S-Dioxide Analogs
	J. Charris, A. Barazarte, N. Gamboa, J. Rodrigues (University of Venezuela, Caracas, Venezuela) charrisj@camelot.rect.ucv.ve

2-PO40	Synthetic Studies of 1, 11-Dioxygenated Canthin-6-ones
	Y. Murakami, H. Suzuki, H. Gyoutoku, M. Adachi, Y. Ebihara, H. Furuya, R. Takashima, S. Kato, H. Okuno (Toho University, Chiba, Japan) ymurakami@cis.ac.jp

2-PO41	Novel Lewis Acid-Catalyzed De-acylation on the C3-Position of Indoles. Findings and Application
	H. Suzuki, H. Yamada, Y. Katono, H. Mizutani, M. Kamijyo, A. Takeuchi, Y. Murakami, H. Okuno (Toho University, Chiba, Japan) suzuki@phar.toho-u.ac.jp

2-PO42	*Synthesis of the Derivatives of Novel Heterocyclic System, benzo[c,d]furo[2,3-f]indole*
	I. Davidenko, S. Popov, Y. Slominsky (National Academy of Sciences, Kiev, Ukraine) spectrum@kv.ukrtel.net

2-PO43	DNA Labeling with Imidazo[4,5-b]phenazine Intercalating Agent
	I. Dubey, I. Davidenko, S. Popov (Spectrum Info Ltd., Kiev, Ukraine) spectrum@kv.ukrtel.net

2-PO44	Synthesis of C-(het)aryl-substituted Anthranilic Acids Employing Pd(0)-catalysed Cross-coupling in Aqueous Media
	S. Popov, L. Matyash, Y. Sogulayev, V. Kysil (Spectrum Info Ltd., Kiev, Ukraine) spectrum@kv.ukrtel.net

2-PO45	Antileukemic Activity of 7-Hydroxy-8-acetylcoumarin N-Benzoyl Hydrazone
	A. Kotali, I.S. Lafazanis, A. Papageorgiou, E. Chrysogelou, Z. Sinakos (University of Thessaloniki, Greece) kotali@eng.auth.gr

2-PO46	Synthesis of Acyl Substituted Pyridine Carbaldehydes
	A. Kotali (University of Thessaloniki, Greece) kotali@eng.auth.gr

2-PO47	A New Transformation in the Synthesis of Heterocycles
	A. Kotali, I.S. Lafazanis (University of Thessaloniki, Greece) kotali@eng.auth.gr

2-PO48	Efficient Synthesis of Novel Pentacyclic 6,7-Dihydro-5a,7a,13,14-tetraaza-pentaphene-5,8-diones
	M. Pereira, J. Guillon, J.M. Léger, C. Jarry, V. Thiéry, TA. Besson (University of Rochelle, France) vthiery@univ-lr.fr

2-PO49	Syntheses and Antioxidant Effects on Lipid Peroxidation of Novel Indole Lipoic Acid Derivatives
	A.S. Gurkan, A. Karabay,Z. Buyukbingol, A. Adejare, E. Buyukbingol (Ankara University, Turkey) sgurkan@pharmacy.ankara.edu.tr

2-PO50	Genotoxicity Studies on Tetrahydronaphthalene Benzimidazole Derivatives
	Z. Ates-Alagoz, F. Balaban, M. Iscan, E. Buyukbingol(Ankara University, Turkey) zates@pharmacy.ankara.edu.tr

2-PO51	Novel Benzimidazoles Containing Substituted İndole or 1,1,4,4-Tetramethyl-1,2,3,4-tetrahydro-naphthalene Fragments
	C. Kus, Z. Ates-Alagoz, T. Coban (Ankara University, Turkey) kus@pharmacy.ankara.edu.tr

2-PO52	Synthesis and Antioxidant Activities of Novel Benzimidazoles
	G. Ayhan-Kılcıgil, C. Kuş, B. Can-Eke, M. Iscan, S. Özbey (Ankara University, Turkey) kus@pharmacy.ankara.edu.tr

2-PO53	Synthesis of New 3-(Substituted Phenacyl)-5-[3’-(4H-4-oxo-1-benzopyran-2-yl)-benzylidene]-2,4-thiazolidinediones and Their Antimicrobial Activity
	M. Tunçbilek, N. Altanlar (Ankara University, Turkey) Tuncbile@Pharmacy.Ankara.Edu.Tr

2-PO54	Methanesulphonamide of 3,5-Dihydro-4H-pyrimido[5,4-b]indol-4-one and [1]Benothieno[3,2-d]pyrimidin-4(3H)-one Derivatives as Potential COX-2 Selective Inhibitors
	S. Barbagallo, G. Granata, A. Perdicaro, A. Marrazzo, A. Santagati, G. Ronsisvalle (University of Catania, Italy)

2-PO55	*Dihalo Indolyl Aryl Sulfones (IASs) Highly Active In Vitro* Against HIV-1 WT and Variants Carrying NNRTI Resistance Mutations**
	G. De Martino, G. La Regina, R. Ragno, A. Coluccia, G. Maga, M. Artico, R. Silvestri (University of Rome, Italy) gabriella.demartino@uniroma1.it

2-PO56	2-Aryl-benzo[b]furans Derivatives for Treatment of Inflammatory Diseases
	Ilario Verpilio, Ornella Letari, Tiziana Piepoli, Antoni Giordani, Lucio C. Rovati (R&D Division of Rottapharm, Monza, Italy) Ilario.Verpilio@rotta.com

2-PO57	Synthesis of Non-Charged Thiamine Mimetics as Inhibitors of Transketolase
	T. Kaplan, B. Bernat, S.A. Boyd, J. De Meese, W.E. DeWolf, Jr., S.S. Gonzales, I. Gunawardana, Y. Le Huerou, C. Lemieux, T.T. Romoff, F. Sullivan, A.A. Thomas, M. Han, S.K. Wright (Array BioPharma, Boulder, USA) tomas.kaplan@arraybiopharma.com

2-PO58	Towards the Synthesis of Polyazole-containing Natural Products
	E. Riego, D. Hernández, F. Albericio, M. Álvarez (University of Barcelona, Spain) eriego@pcb.ub.es

2-PO59	Synthesis and Photochemical Reactions of 1-Substituted 5-Halo-7-azaisatins
	J. Tatsugi, Y. Tsuchiya (Aichi Institute of Technology, Toyota, Japan) *jtatsugi@aitech.ac.jp*

2-PO60	Fused Zwitterionic Heterocyclic: the Synthesis of 2,4,5,6-Tetrahydropyrrolo[1,2-c][1,2,3]triazolio-5-olate
	Y. Morzherin, I. Geide, J. Nein, S. Gladkova (Urals State Technical University, Russia) morjerine@htf.ustu.ru

2-PO61	The Obtainment and the Evaluation of the Antimicrobial Activity of Some Sulfonylhydrazinothiazoles
	V. Zaharia, A. Silvestru, M. Curticapean, B. Tiperciuc, N. Palibroda (University of Medicine and Pharmac, Romania) vzaharia@umfcluj.ro

2-PO62	The Evaluation of the Anti-inflammatory Activity of Some New Synthetic Flavones
	B. Tiperciuc, A. Parvu, F. Rada, O. Oniga, D. Ghiran (UMF Iuliu Hatieganu, Cluj-Napoca, Romania) brandu32@yahoo.com

2-PO63	The Synthesis of Novel Anhydroglycosidic Fluoroindolocarbazoles as Topoisomerase I Inhibitors
	E. Ruediger, M. Saulnier, C. Bachand, F. Beaulieu, C. Fairchild, D. Frennesson, M. Mahler, A. Martel, D. St. Laurent, D. Vyas, K. Zimmerman, B. Long, B. Balasubramanian (Bristol-Myers Squibb, Candiac, Canada) edward.ruediger@bms.com

2-PO64	New Synthesis and Mass Spectra Properties of Derivatives of 1H-4-[p-Substituted)phenyl]-7-[(o- and p-substituted)phenylthio]-1,5-benzodiazepines
	E. Cortés Cortés, O. García Mellado (University of Coyoacán, México) ecortes@servidor.unam.mx

2-PO65	Synthesis and Determination of the Biological Activity of New Derivatives of 1,4-Benzodiazepin-2-one as Powerful Sedative-hypnotic and Anxiolytic
	E. Cortés Cortés, O. García Mellado (University of Coyoacán, México) mellado@servidor.unam.mx

2-PO66	Synthesis of Oxo- and Thio-phosphoryl (C-N-O and C-N-S Pincers) and Pyridinyl (C-N-N Pincers) Cyclopalladated Indole Derivatives
	A. Penoni, G. Palmisano, S. Tollari, A. Coalizzi (Università dell’Insubria, Como, Italy) andrea.penoni@uninsubria.it

2-PO67	*Novel Synthesis of Azaindoles via* Catalytic Reductive Annulation of Nitropyridines with Alkynes**
	G. Palmisano, A. Penoni, S. Tollari, K. M. Nicholas (Università dell’Insubria, Como, Italy) andrea.penoni@uninsubria.it

2-PO68	Indole cPLA₂a Inhibitors: Chemistry and SAR at the C-3 Position
	L. Chen, W. Wang, J.C. McKew, K. Lee, S. Tam, P. Thakker, F. Sum, K. Wu, L. Wooder, M. Shen, W. Zhang, J.D. Clark (Wyeth Research, Cambridg, USA) Lchen@wyeth.com

2-PO69	Synthesis of 1-Acylisoquinolines
	E. Sanchez-Larios, A. Vazquez (UNAM Ciudad Universitaria, Mexico) joseavm@servidor.unam.mx

2-PO70	The Synthesis of Some Polycyclic N-H Acids with Quinoxaline, Pyrazole and [1,2,4]Triazine Cycles
	I. Fryšová, J. Slouka (Palacký University, Olomouc, Czech Republic) fryšova@orgchem.upol.cz

2-PO71	A Synthesis of some Benzimidazole-2-carboxamide Aryl-hydrazones and Study of their Structure
	I. Fryšová, J. Slouka (Palacký University, Olomouc, Czech Republic) fryšova@orgchem.upol.cz

2-PO72	The Double Course of Cyclization of 3-(2-Aminobenzyl)-1,2-dihydro-quinoxalin‑2‑one
	I. Fryšová, J. Slouka, A. Lyčka, T. Gucký (Palacký University, Olomouc, Czech Republic) fryšova@orgchem.upol.cz

2-PO73	Synthesis of Isoindolinones by Cyclization of Carbamoyl Radicals to Aromatic Systems
	L.D. Miranda, L.G. López (Universidad Nacional Autónoma de México, Coyoacán, México) lmiranda@servidor.unam.mx

2-PO74	A New Method for the Synthesis of 2,5-Bisheteroaryl-3,6-dichloro-1,4-benzoquinones
	R.E. Valters, N.G. Batenko, G.A. Karlivans (Riga Technical University, Latvia) rvalters@latnet.lv

2-PO75	Synthesis of Substituted 2-Phenyl-3-hydroxy-4(1H)-quinolinones Substituted with Carboxylic Group and Their Cytotoxicity Screening
	M. Soural, J. Hlaváč, P. Hradil, M. Hajdůch, V. Bertolasi (University of Palacký, Olomouc, Czech Republic) hlavac@prfnw.upol.cz

2-PO76	Synthesis and QSAR Exploration Studies of Some Condensed Pyrimido[4,5-d]pyrimidines as Potential Antimicrobial Agents
	P. Sharma, A. Kumar, N. Rane (Devi Ahilya University, Indore, India) na_rane@yahoo.com

2-PO77	ZnCl₂ Assisted Synthesis of Benzimidazoles Under Microwave Irradiation
	S. Rostamizadeh, M. Nojavan (K.N.Toosi Universty of Technology. Tehran, Iran) rostamizadeh@hotmail.com

2-PO78	One Pot Procedure to 1,2,4-Triazoles
	S. Rostamizadeh, M. Nojavan (K.N.Toosi Universty of Technology. Tehran, Iran) rostamizadeh@hotmail.com

2-PO79	Pyrrolo[2,1-d][1,2,3,5]tetrazin(3H)-One a New Class of Azolotetrazines Endowed of Antitumor Activity: Study of the Mechanism of Action
	G. Viola, F. Dall'Acqua, D. Vedaldi, E. Fortunato, G. Basso, P. Diana, G. Dattolo, G. Cirrincione (University of Padova, Italy) francesco.dallacqua@unipd.it

2-PO80	Synthesis of New Antitumour Azoles
	A.J. McCarroll, C.G. Mortimer, G. Wells, J.M. Berry, A.D. Westwell, M.F.G. Stevens (Centre for Biomolecular Sciences, Nottingham, UK) andrew.mccarroll@nottingham.ac.uk

2-PO81	Novel Oxidation Product of Antitumour Azoles
	A. Martorana, A.D. Westwell and M.F.G. Stevens (Centre for Biomolecular Sciences, Nottingham, UK) Martorana@unipa.it

2-PO82	Synthesis of New 5-Azaindolocarbazoles
	G. Coudert, M. Lefoix, J.Y. Mérour, S. Routier (Université d’Orléans, France) gerard.coudert@univ-orleans.fr

2-PO83	Two Different Approaches to the Synthesis of 1H-5-Amino-4-amidinoimidazoles
	M. Zaki, M.A. Carvalho, M.F. Proença (Universidade do Minho, Braga, Portugal) mzaki@quimica.uminho.pt

2-PO84	Phenylpyrroloquinolinones: A New Class of Antimitotic Agents
	V. Gasparotto, G. Chiarelotto, I. Castagliuolo, M.G. Ferlin (University of Padova, Italy) venusia.gasparotto@unipd.it

2-PO85	Access to Various 3 and 5-(1,2,4-Triazinyl)Amines under Microwave Activation
	D. Poullain, J.R. Cherouvrier, J. Guillard, B. Lebret, M.C. Viaud (Université de Tours, France) didier.poullain@cea.fr

2-PO86	Solvent-Free Synthesis of Diindolylalkanes Employing Microwave Energy and a Bentonitic Clay
	J.G. Penieres Carrillo, S. Lagunas Ávila, E.Valdez Rojas, J.M. Aceves Hernández, J. Guadalupe García Estrada (Universidad Nacional Autónoma de México, México) penieres@servidor.unam.mx

2-PO87	Preparation of Diheterocyclic Compounds with Potential Pharmacological Interest
	J.G. Penieres Carrillo, E. Valdez Rojas, J.M. Aceves Hernández, C. Álvarez Toledano, J. Guadalupe López Cortés (Universidad Nacional Autónoma de México, México) penieres@servidor.unam.mx

2-PO88	Substituent Effects in the Ring-Chain Tautomerism of Imidazo[5,1-a]- and Pyrimido[6,1-a]Isoquinolines
	F. Fülöp, Z. Zalán, A. Hetényi, L. Lázár (University of Szeged, Hungary) fulop@pharm.u-szeged.hu

2-PO89	Unexpected Synthesis of 1,2,4-Triazolo[1,5-d]1,2,4-triazine-5-Thiones
	M.M. Heravi (Azzahra University, Tehran, Iran) mmh1331@yahoo.com

2-PO90	Efficient S-Transalkylation of 2,2'-Bipyridine Methyl Sulfides and its Application for Synthesis of Macrocycles
	I. Buczek, K. Kalinska, J. Nowaczyk, D. Branowska, A. Rykowski (University of Podlasie, Siedlce, Poland) rykowski@ap.siedlce.pl

2-PO91	Solvent-Free Synthesis of 2-Aminothiazoles and 2-Substituted Benzothiazoles on Inorganic Supports under Microwave Irradiation
	M. Kodomari, K. Yamashita, Y. Tamaru (Shibaura Institute of Technology, Tokyo, Japan) kodomari@sic.shibaura-it.ac.jp

2-PO92	The Syntheses and the SAR of Potent CRF₁ Antagonists in the Pyridine Series
	Y.L. Chen, E. Brooks, M.L. Corman, J. Forman, J. Freeman, R.J. Gallaschun, R.S. Mansbach, A. Schmidt, D.W. Schulz, F.D. Tingly, F. Yang (Pfizer Inc, Groton, USA) yuhpyng_l_chen@groton.pfizer.com

2-PO93	*Regioselectivity in the Addition of Vinyl and Aromatic Grignard Reagents to bis(2-benzothiazolyl) ketone: C- versus* O-alkylation**
	C. Boga, M. Mazzacurati, P.E. Todesco (Universita’ di Bologna, Italy) boga@ms.fci.unibo.it

2-PO94	High Atom-Economical One-Pot Synthesis of Tertiary Phosphines Using a Benzothiadiphospholic Heterocycle as Phosphorus Donor Reagent
	G. Baccolini, C. Boga, M. Mazzacurati (Universita’ di Bologna, Italy) boga@ms.fci.unibo.it

THURSDAY, AUGUST 4			ORAL CONTRIBUTIONS

15:00 – 17:00

Session A		(Sala Orsa)
		Chair: Professor Anna Maria Almerico (University of Palermo, Italy)

4A-OC18		Synthesis of Novel Quinolines and Indoles via Ring-Expansion of Squaric Acid Ester Derivatives
		B.C.G. Söderberg, K.D. Fisher, P.S. Zehr, R. Kayali, A. Villanueva-Reddon,O. Robles-Resendiaz, E. Pena-Cabrera (West Virginia University, Morgantown, USA) bjorn.soderberg@mail.wvu.edu

4A-OC19		Applications of a Novel Pd(II)-Precatalyst for Solid-Phase Assisted C-C Cross Coupling of Heterocyclic Bromides Under Microwave Irradiation in Water
		K.M. Dawood, A. Kirschning (Universität Hannover, Germany) kamal.dawood@oci.uni-hannover.de

4A-OC20		Tandem Double Palladium-Catalyzed Aminations: Synthesis of Dipyrido[1,2-a:3¢,2¢-d]imidazole and its Benzo- and Aza-analogues
		K.T.J. Loones, B.U.W. Maes, R.A. Dommisse, G.L.F. Lemière (University of Antwerp, Belgium) bert.maes@ua.ac.be

4A-OC21		Selenium-Containing Heterocycles from Isoselenocyanates
		G.L. Sommen, A. Linden, H. Heimgartner (University of Zürich, Switzerland) heimgart@oci.unizh.ch

4A-OC22		New Aspects of the Utilization of Vicarious Nucleophilic Substitution (VNS) in the Synthesis of Indoles
		S. Radl, J. Cerny (Zentiva – Research Institute of Pharmacy and Biochemistry, Prague, Czech Republic) Stanislav.radl@zentiva.cz

4A-OC23		Synthesis and Herbicidal Properties of the Thaxtomin Group of Phytotoxins
		P. Bentley, D.A. Griffin, C.J. Mathews, D. McCormack, P. Worthington (Syngenta, Jealott’s Hill International Research Centre, Bracknell, UK) paul.worthington@syngenta.com

4A-OC24		Alkyl 3-(Dimethylamino)propenoates and Related Enaminones in the Synthesis of Aplysinopsins, Meridianines, Dipodazines and Their Synthetic Analogs
		B. Stanovnik, Z. Časar, R. Jakše, J. Wagger, D. Bevk, L. Selič, J. Svete, A. Meden, A. Golobič, U. Grošelj (University of Ljubljana, Slovenia) branko.stanovnik@fkkt.uni-lj.si

4A-OC25		Synthetic Approach to Aristolactam Natural Products Utilizing Palladium-Mediated Tandem Reactions
		E.T. Pelkey, M.J. Garman, M.E. Liquori (Hobart and William Smith Colleges, Geneva, NY, USA) pelkey@hws.edu

Session B		(Sala Nova)
		Chair: Professor Enrico Marcantoni (University of Camerino, Italy)

4B-OC18		New Isothiazole C-C Coupling Chemistry
		I.C. Christoforou, P.A. Koutentis (University of Cyprus, Cyprus) irenech@cytanet.com.cy

4B-OC19		Synthesis and Reactivity of New Azolyldienes, Trienes, and Their Aza Analogues
		G. Hajós, I. Nagy, Z. Riedl (Hungarian Academy of Sciences, Budapest, Hungary) ghajos@chemres.hu

4B-OC20		Introduction of Linking Groups by Alkylation of Fluorescent Heterocycles
		N.S. Badgujar, S. Kovackova, M. Pazicky, A. Terec, G. Uray, W. Stadlbauer (Karl-Franzens University of Graz, Austria) naresh12317@rediffmail.com

4B-OC21		N-Formylpyrrolidine Derivatives for Enantioselective Reduction of Aromatic Ketones Using Trichlorosilane
		Y. Matsumura, K. Ogura, O. Onomura (Nagasaki University, Japan) matumura@net.nagasaki-u.ac.jp

4B-OC22		Novel Chemistry of 2- and 3-Nitroindoles
		G.W. Gribble, S. Roy, T.L.S. Kishbaugh, E.T. Pelkey, H.A. Trujillo (Dartmouth College, Hanover, USA) ggribble@dartmouth.edu

4B-OC23		Stereoselective Synthesis of Enantiomerically Pure 2-Iso-Oxacephem Analogues of Thienamycin
		Z. Sánta, J. Nagy, J. Nyitrai (Budapest University of Technology and Economics, Hungary) sanzs@mail.bme.hu

4B-OC24		Stereoselective Homologation of Boronates in the Total Synthesis of the Actin-targeting Metabolite (–)-Microcarpalide
		P. Davoli, F. Prati (University of Modena and Reggio Emilia, Modena, Italy) prati.fabio@unimore.it

4B-OC25		Synthesis of Razaxaban, a Highly Potent, Selective and Orally Bioavailable Factor Xa Inhibitor
		J.-H. Sun, Y.B. Bethel, C.S. Brosz, F. Jin, A.C. Tabaka-Blom, T.L. Taylor, J. Yan, C.A. Teleha, M.L. Quan, C.G. Clark, R. Li, P.Y.S. Lam, R.R. Wexler (Bristol-Myers Squibb Co., Princeton, USA) jung-hui.sun@bms.com

Session C		(Sala Orione)
		Chair: Professor Jose Sepulveda-Arques (University of Valencia, Spain)

4C-OC18		New Reactions with Sterically Congested 1-Azabicyclo[1.1.0] butanes
		M. Woźnicka, G. Mlostoń, K. Urbaniak (University of Lodz, Poland) gmloston@uni.lodz.pl

4C-OC19		Synthesis and Anticancer Activity of Novel Compounds Derived from 2-Substituted-4(1H)-quinolinones
		J. Hlaváč, P. Hradil, M. Hajduch, J. Slouka (University of Palacky, Olomouc, Czech Republic) hlavac@prfnw.upol.cz

4C-OC20		New Biologically Actives in the Series of Fluorinated Benzazoles and Benzazines
		V.N. Charushin,S.K. Kotovskaya,N.M. Perova,Z.M. Baskakova, O.N. Chupakhin,E.F. Belanov, A.G. Pokrovsky (Urals State Technical University, Russia) charushin@htf.ustu.ru

4C-OC21		Asymmetric Paternò-Büchi Reaction on Furan Derivatives: the Hydroxyl Directing Effect in 2-Furylmethanols
		M. D’Auria, L. Emanuele, R. Racioppi (University of Basilicata, Potenza, Italy) dauria@unibas.it

4C-OC22		New Classes of Calcium Channels Modulators: Thiazinooxadiazol-3-one and Oxadiazol-5-one Derivatives
		R. Budriesi, E. Carosati, A. Chiarini, B. Cosimelli, G. Cruciani, P. Ioan, D. Spinelli, R. Spisani (Università degli Studi di Bologna,Italy) spisani@ms.fci.unibo.it

4C-OC23		New Calcium Channel Modulators Discovered by Virtual Screening
		R. Budriesi, E. Carosati, A. Chiarini, B. Cosimelli,G. Cruciani, P. Ioan, D. Spinelli, R. Spisani (Università degli Studi di Bologna,Italy) emanuele@chemiome.chm.unipg.it

4C-OC24		Design, Synthesis and SAR of Novel Phosphonates as Potent and Selective FBPase Inhibitors with Oral Efficacy in Rodent Models of Type 2 Diabetes
		Q. Dang, M.D. Erion, K.R. Reddy, S. Rao Kasibhatla, M. Rami Reddy, P.D. van Poelje (Metabasis Therapeutics, San Diego, USA) dang@mbasis.com

4C-OC25		Synthesis and Biological Activity of Ring E/F and Ring E/B Analogues of Methyllycaconitine
		S.C. Bergmeier, J. Huang, D.D. Reed, D.B. McKay, S. McKay (Ohio University, USA) bergmeis@ohio.edu

Session D		(Sala Mizar)
		Chair: Professor Cosimo D. Altomare (University of Bari, Italy)

4D-OC18		*Novel Synthesis of N-Methoxyindoles via* Reductive Annulation of Nitrosoarenes with Alkynes**
		G. Palmisano, A. Penoni, S. Tollari, K.M. Nicholas (Università degli Studi dell’Insubria, Como, Italy) andrea.penoni@uninsubria.it

4D-OC19		A New Microwave-Assisted Solid Phase Synthesis for the Preparation of Imidazole Libraries: a Catch & Release Strategy
		L. De Luca, G. Giacomelli, A. Porcheddu (Università degli Studi di Sassari, Italy) ldeluca@uniss.it

4D-OC20		An Efficient One-pot Synthesis of 1,2-Substituted 7-Azaindoles
		Z. Wei, H. Yang, C. Walpole, R. Dolaine (AstraZeneca R&D Montreal, Canada) john.wei@astrazeneca.com

4D-OC21		Recent Advances in 1,2,4-Oxadiazole Chemistry
		A. Pace, I. Pibiri, A. Palumbo Piccionello, S. Buscemi, N.Vivona (Università degli Studi di Palermo, Italy) pace@unipa.it

4D-OC22		Synthesis, Substitution and Ring Closure Reactions of Pyrido [3,2,1-jk]carbazol-6-ones
		H.V. Dang, B. Knobloch, A. Pfaffenschlager, T. Kappe, W. Stadlbauer (Karl-Franzens University of Graz, Austria) dvhoai@yahoo.com

4D-OC23		Novel Triple Hydrogen Bonded AAA-DDD Heterocomplexes with High Binding Stability
		S.D, Djurdjevic, D.A, Leigh, H. McNab (University of Edinburgh, UK) Smilja.Djurdjevic@ed.ac.uk

4D-OC24		6→8 and 7→9 Membered Rings Expansion in Annulated Tetrahydropyridines and Azepines – Novel Approach Toward Azocine and Azonine Derivatives with Substantial Bioactivity
		L.G. Voskressensky, T.N. Borisova, C. Altomare, L.N. Kulikova, A.V. Varlamov (Organic Chemistry Department of the RPFU, Moscow, Russia) lvoskressensky@sci.pfu.edu.ru

4D-OC25		Applications of CeCl₃·7H₂O-NaI System Towards the Formation of Heterocyclic Structures
		E. Marcantoni,M. Massaccesi, M. Petrini, G. Bartoli, L. Sembri (University of Camerino, Italy) massimo.massaccesi@unicam.it

THURSDAY, AUGUST 4		POSTERS SESSION 4-PO1 ÷ 4-PO94

17:00 - 18:30

4-PO1	Synthesis and X-ray Crystal Structures of Novel Thiopurine Analogues
	M. Ikaunieks, S. Belakovs, M. Madre (Latvian Institute of Organic Synthesis, Latvia) ikauneksl@osi.lv

4-PO2	Modified Purine Heterocycles: Synthesis and Alkylation Studies
	M. Madre, M. Ikaunieks (Latvian Institute of Organic Synthesis, Latvia) madre@osi.lv

4-PO3	Synthesis and Investigations of Heteryl(Aryl) 3-Cyano-5,5-dimethyl-2(5H)-furanones and 3-Cyano-6,6-dimethyl-5,6-dihydro-2(2H)-pyranones
	L. Leite, D. Jansone, M. Fleisher, S. Belyakov, V.Poroikov, E. Lukevics (Latvian Institute of Organic Synthesis, Latvia) leite@osi.lv

4-PO4	Computer Design of the Biologically Active Compounds on Unsaturated Aryl(hetaryl)lactones and Lactams Bases
	A. Skorova, N. Veretennikova, D. Jansone, L. Leite, E. Lukevics (Latvian Institute of Organic Synthesis, Latvia) hgs@osi.lv

4-PO5	Synthesis of N,N'-Unsymmetrically Substituted 1,3-Diketimines and Physical Properties of Their Copper(II) Complexes
	K. Park, W.J. Marshall (Materials Science and Engineering, Wilmington, USA) kyung-ho.park@usa.dupont.com

4-PO6	New Recyclable Materials for L-Proline-Catalyzed Aldol Reactions
	M. Gruttadauria, S. Riela, C. Aprile, P. Lo Meo, R. Noto (University of Palermo, Italy) mgrutt@unipa.it

4-PO7	Designing Fluorous Domains. Pyridinium Salts Bearing a Perfluoroalkylated Oxadiazole Moiety
	I. Pibiri, A. Pace, A. Palumbo Piccionello, S. Buscemi, N. Vivona (University of Palermo, Italy) pibiri@unipa.it

4-PO8	Fluoroarylation of Hydroxylated Molecules with 5-Pentafluorophenyl-1,2,4-Oxadiazoles
	A. Palumbo Piccionello, A. Pace, I. Pibiri, S. Buscemi, N. Vivona (University of Palermo, Italy) apalumbo@unipa.it

4-PO9	A Joint Experimental and Computational Study on the Oxidative Cyclization of Aldehyde Thiosemicarbazones Induced by Potassium Ferricyanide and by Tris(p-bromophenyl)amino Hexachloro-Antimoniate
	P. Lo Meo, M. Gruttadauria, R. Noto (Università degli Studi di Palermo, Italy) rnoto@unipa.it

4-PO10	Total Synthesis of Enantiopure TAN1251A, TAN1251C and TAN1251D by Means of Aromatic Oxidation.
	T. Honda, J. Takayama, H. Mizutani (Hoshi University, Tokyo, Japan) honda@hoshi.ac.jp

4-PO11	Studies Toward the Synthesis of Furanocembrane Bipinnatin J: Synthesis of a 2,3,5-Trisubstituted Furfuryl Ether Intermediate
	M. Tsubuki, K. Takahashi, K. Sakata, T. Honda (Hoshi University, Tokyo, Japan) tsubuki@hoshi.ac.jp

4-PO12	Use of Design of Experiments to Optimize the Synthesis of Tropane-based Natural Product Libraries
	Pawel Nowak (Wyeth Research,, NY, USA) nowakp@wyeth.com

4-PO13	Ring-to-ring Interconversion: a Reactivity Study of Some Substituted Z-Phenylhydrazones of the 5-Amino-3-benzoyl-1,2,4-oxadiazole
	F. D'Anna, V. Frenna, G. Macaluso, V. Pace, R. Spisani, D. Spinelli (University of Palermo, Italy) vitalbapace@tiscali.it

4-PO14	[2+2]-Regio Carbonylative Cycloaddition of Allyl Bromides to Aryl and Heteroaryl Substituted Imines
	L. Troisi, L. De Vitis, C. Granito, E. Pindinelli (University of Lecce, Italy) pindiwind@inwind.it

4-PO15	Synthesis and Functionalization of N-Heteroaryl-substituted-aziridines
	L. Troisi, C. Granito, C. Carlucci, F. Bona (University of Lecce, Italy) claudia.carlucci@email.it

4-PO16	An Efficient Synthesis of Benzazepine Skeleton
	M. Miyake, K. Nagami, T. Nishi (Bulk Pharmaceutical Chemicals Division, Tokushima, Japan) m_miyake@otsuka.jp

4-PO17	Synthesis of the Side Chain Unit of Salacinol Analogue with Sulfonium–carboxylate Inner Salt
	O. Muraoka, S. Toya, T. Minematsu, T. Yasuhara (Kinki University, Osaka, Japan) muraoka@phar.kindai.ac.jp

4-PO18	Synthesis of Acyclic Nucleotide Analogues Possessing a Difluoromethylene Phosphonyl Group
	Y. Yuasa, T. Murano, T. Yokomatsu, S. Shibuya (Tokyo University, Japan) yuasay@ps.toyaku.ac.jp

4-PO19	A New Route to Orally Active Drugs: Substrate Studies on the PepT1 Transporter
	P. Bailey; R. Pettecrew (University of Manchester, UK) R.Pettecrew@postgrad.manchester.ac.uk

4-PO20	The Total Synthesis of (-)-Raumacline
	P.D. Bailey; P.D. Clingan; T.P.H. Dang; R.A. Price (University of Manchester, UK) r.price@manchester.ac.uk

4-PO21	Thermal Fragmentation of Benzoin Arylsulfonylhydrazone Derivatives
	Abdullah A. Al-Ahamadi, Abd El-Aal M. Gaber (Umm Al-Qura University, Kingdom of Saudia Arabia) gaber137@hotmail.com

4-PO22	Synthesis of a New Class of Modulators of the NMDA Receptor Function
	C.R. Noe, M.L. Berger, C. Stanetty (University of Vienna, Austria) christian.stanetty@univie.ac.at

4-PO23	The Competitive Formation of Purine and Imidazoimidazoline
	C. Correia, M. Alice Carvalho and M. Fernanda Proença (Universidade do Minho, Braga, Portugal) mac@quimica.uminho.pt

4-PO24	A New Synthesis of Arcyriaflavin-A
	D. Alonso, E. Caballero, M. Medarde, Fe. Tomé (University of Salamanca, Spain) escab@usal.es

4-PO25	Synthesis of 6,6-Spiroketal Natural Products
	T. Shimizu (Institute of Physical and Chemical Research, Saitama, Japan) tshimizu@riken.jp

4-PO26	An Alternative Process for Preparing a 5HT1A Antagonist, SRA-333
	A.W. Chan, G. Feigelson, J. Ren, A. Sharma, J. Zeldis (Wyeth Research, NY, USA) chanaw1@wyeth.com

4-PO27	Process for the Synthesis of 2,3-Dihydro-1,4-Dioxino-[2,3-f] Quinoline and Its Derivatives
	A.W. Chan, T. Curran, W. Chew, S. Iera, J. Sellstedt (Wyeth Research, NY, USA) chanaw1@wyeth.com

4-PO28	Synthesis and Characterization of Metallo Supramolecular Polymers Containing Terpyridine Ligands
	I. Chen, H. Lin (National Chiao Tung University Hsinchu, Taiwan) linhc@cc.nctu.edu.tw

4-PO29	Design and Synthesis of New 3-Aryl-5-oxoprolines as Potential Ligands for Human Cloned Endothelin Receptors
	G. Romeo, L. Materia, M. Modica, V. Pittalà, L. Salerno, M. Siracusa, F. Guerrera, A. Cagnotto, I. Mereghetti, T. Mennini, F. Russo (University of Catania, Italy) gromeo@unict.it

4-PO30	Artificial Oxidases Based on Nanoaggregates Containing Amphiphilic Flavin Analogs
	L. Marková, R. Cibulka, F. Hampl (Institute of Chemical Technology, Prague, Czech Republic) cibulkar@vscht.cz

4-PO31	Coordination of Lipophilic Alkyl (2-Pyridyl) Ketoximes to Metal Ions in Micellar Solutions
	R. Cibulka, R. Jurok, T. Schulz, F. Hampl (Institute of Chemical Technology, Prague, Czech Republic) hamplf@vscht.cz

4-PO32	New Metal Ion Extractants with 2-(1-Hydroxyiminoalkyl)pyridine Chelating Subunit
	E. Svobodová, F. Hampl, R. Cibulka, F. Liška (Institute of Chemical Technology, Prague, Czech Republic) hamplf@vscht.cz

4-PO33	Morpholinomethylsilanes
	N. Erchak, K. Pypowski, M. Zielonka, T. Koval, E. Olszewska, S. Lenivko, A. Rykowski, E. Lukevics (University of Podlasie, Siedlce, Poland) erchak@ap.siedlce.pl

4-PO34	Poly(ethylene glycol) (PEG) as a Green and Recyclable Reaction Media for Highly Enantioselective Hydrogenation of Quinolines
	Q. Fan, L. Xu, K. Hung Lam, A.S.C. Chan (Chinese Academy of Sciences, Beijing, China) fanqh@iccas.ac.cn

4-PO35	Recent Developments in the Chemistry of Heterocyclic Ketene Aminals
	Z. Huang , T. Peng, S. Yan, J. Liao, X. Yuan, C. Yu, M. Wang (Chinese Academy of Sciences, Beijing, China) huangzt@public.bta.net.cn

4-PO36	Supramolecular Chemistry of Heteroatom-bridged Calixarenes: Synthesis, Structure, Reaction and Molecular Recognition of Nitrogen- and/or Oxygen-bridged Calixpyridines and Calixtriazines
	M. Wang, X. Zhang, H. Yang, H. Gong, C. Du, Q. Zheng, D. Zhang (Chinese Academy of Sciences, Beijing, China) mxwang@iccas.ac.cn

4-PO37	A Concise Synthesis of (-)-Hyacinthacine A₂ Based on An Improved Preparation of D-Xylose-derived Polyhydroxylated Cyclic Nitrone
	C. Yu, M. Huang (Chinese Academy of Sciences, Beijing, China) yucy@iccas.ac.cn

4-PO38	Efficient Synthesis and Resolution of the Inherently Chiral Calix[4] quinolines in the Upper Rim
	C. Chen, R. Miao, Z. Huang (Chinese Academy of Sciences, Beijing, China) cchen@iccas.ac.cn

4-PO39	The Interaction of Scopolamine with Amines
	L.I. Vlasova, N.Z. Baybulatova, M.S. Yunusov (Academy of Sciences, Octyabrya, Russia,) dokichev@anrb.ru

4-PO40	Synthesis and Properties of SMAPs 1-Phospha-4-silabicyclo[2.2.2] octane Derivatives
	A. Ochida, T. Miyahara, S. Ito, M. Sawamura (Hokkaido University, Sapporo, Japan) atsuko@sci.hokudai.ac.jp

4-PO41	New Expanded Phthalocyanine-like Macrocycles, New Expanded Phthalocyanine-like Macrocycles
	V.M. Derkacheva, A. Muranaka, N. Kobayashi, E.A. Lukyanets (Organic Intermediates and Dyes Institute, Moscow, Russia) lab31@co.ru

4-PO42	Studies on Total Synthesis of the Marine Pyridoacridine Alkaloid: Neoamphimedine and Related Compounds
	E. Delfourne, J. Poyo (Université Paul Sabatier, Toulouse, France) delfourn@chimie.ups-tlse.fr

4-PO43	Preparation, Structure, and Solvatochromic Behaviour of Near Infrared Absorbing Azomethine Dyes Based on a 2H-Pyrazolo[3,4-b]pyridine-3,6-dione Nucleus
	Yoshio Inagaki, Masaki Hamashima, and Kazuo T. Nakamura (Fuji Photo Film, Kanagawa, Japan) Yoshio_inagaki@fujifilm.co.jp

4-PO44	Highly Soluble Quinoidal Oligothiophenes as Novel Near-infrared Dyes
	T. Otsubo, T. Takahashi, K. Matsuoka, K. Takimiya, Y. Aso (Hiroshima University, Japan) otsubo@hiroshima-u.ac.jp

4-PO45	Synthesis and Luminescence Properties of 2,6-Diaryl-4-(2-substituted thienyl-5-yl)pyridines and Their Metal Complexes
	R. Nakajima, K. Mima, N. Shiraishi, Y. Tsurumoto, T. Tamura, T. Matsumura-Inoue, K. Tsukagoshi (Doshisha University, Kyoto, Japan) rnakajim@mail.doshisha.ac.jp

4-PO46	Development and Scaleup Challenges in the Regioselective Synthesis of Temsirolimus
	W. Chew, C. Shaw (Wyeth Research, Montreal, Canada) cheww@wyeth.com

4-PO47	Online Reaction Monitoring in the Manufacture of CCI-779 Boronate Intermediate
	W. Chew, W. McMahon, C. Shaw (Wyeth Research, Montreal, Canada) cheww@wyeth.com

4-PO48	Synthesis and Purification with Sepacore® of a Branched Ru(II) Polypyridine Complex
	A. Corsaro, U. Chiacchio, I. Fragalà, A. Gulino, V. Pistarà (University of Catania, Italy) vpistara@unict.it

4-PO49	Synthetic Studies of Kopsia Alkaloids
	S. Arai, T. Watanabe, J. Maruyama, N. Sakai, A. Nishida (Chiba University, Japan) arai@p.chiba-u.ac.jp

4-PO50	The Use of Enantiomerically Pure αβ-Unsaturated N-Acyl-oxazolidin-2-one in Diastereoselective Baylis-Hillman Type Reaction Mediated by SmI₂
	M. Mamaghani, A. Badrian (University of Guilan, Rasht, Iran) chem41@guilan.ac.ir

4-PO51	One-pot Facile Conversion of Baylis-Hillman Adducts into 1,5-Diarylpyrazoles Under Microwave Condition
	M. Mamaghani , K. Tabatabaeian, M. Shirsavar, A. Bagheri, M. Mirzaei (University of Guilan, Rasht, Iran) m-chem41@guilan.ac.ir

4-PO52	Reactivity of Substituted Maleïmides with Respect to Reagents such as Thiocyanate: PM3 and DFT / B3LYP Calculations
	`Y. Akacem, K. Zaioua, N. Achoui, S. Bouzroura, B. Kolli`(`University U.S.T.H.B, Algiers, Algeria`) `akacem2000@yahoo.fr`

4-PO53	Synthesis and Conformational Studies of a Peptide Linked Chlorin Dimer as a Model Compound for the Photosynthetic Reaction Centre
	F.P. Montforts, T. Könekamp, A. Ruiz, J. Duwenhorst, W. Schmidt (University of Bremen, Germany) Thorsten@chemie.uni-bremen.de

4-PO54	A Synthetic Approach Directed to Tolyporphin K
	F.P. Montforts; R.I. Sáez Díaz (University of Bremen, Germany) saez@chemie.uni-bremen.de

4-PO55	Enzymatic Resolution of cis-4-Hydroxy-2,3-dimethyl-cyclohex-2en-1-carboxylic Acid Ethylester, a Building Block for the Synthesis of Enantiomerically Pure Chlorophyl A
	J.M. dos Santos Filho, J. Stelten, F.P. Montforts (University of Bremen, Germany) lefufpe@chemie.uni-bremen.de

4-PO56	Synthesis of Chlorins from Naturaly Occurring Porphyrin as Potential Photosensitizers for Photodynamic Therapy (PDT)
	A. Kozielec, F.P. Montforts (University of Bremen, Germany) kozielec@chemie.uni-bremen.de

4-PO57	The Thermal and Photochemical Decomposition of 2,5-Dihydro-2,2-dimethoxy-5,5-dimethyl-1,3,4-oxadiazole - a Matrix Spectroscopic Study of Dimethoxycarbene
	H. P. Reisenauer, P. R. Schreiner, J. Romanski, G. Mloston, J. Warkentin (University of Lodz, Poland) gmloston@uni.lodz.pl

4-PO58	Unexpected Course of the Reaction of 2-Unsubstituted Imidazole N-Oxides with 1,1-Dicyjano-2,2-bis(trifluoromethyl)ethylene
	M. Jasinski, G. Mloston (University of Lodz, Poland) gmloston@uni.lodz.pl

4-PO59	Unclassical Pschorr and Sandmeyer Reactions in Pyrazole Series
	B. Maggio, G. Daidone, D. Raffa, S. Plescia, G. Bombieri, F`.` Meneghetti (University Palermo, Italy) gdaidone@unipa.it

4-PO60	Lipophilicity Screening of Oxadiazole Modified Phenylureas and Benzamides Enhancing Analgetic Agents
	G. Bazylak (Nicolaus Copernicus University, Bydgoszcz, Poland) gbazylak@cm.umk.pl

4-PO61	One-pot Four-Step Synthesis of Cerpegin
	J. Lazaar, C. Hoarau, F. Mongin, F. Trécourt, A. Godard, G. Quéguiner, F. Marsais (Université et INSA de Rouen, France) guy.queguiner@insa-rouen.fr

4-PO62	New Tricyclic Ring System of Biological Interest Thieno[3,2-e] [1,2,3]triazolo[1,5-a]pyrimidine Through Domino Reactions of 2-Azidothiophene
	A. Lauria, C. Patella, P. Diana, P. Barraja, A. Montalbano, G. Dattolo, G. Cirrincione, A.M. Almerico (Università degli Studi di Palermo, Italy) patella@unipa.it

4-PO63	Glucuronidation of Isoflavones
	O. Soidinsalo, K. Wähälä (University of Helsinki, Finland) otto.soidinsalo@helsinki.fi

4-PO64	Synthesis of Novel Pyrrolidine Fused Tetraazachlorins and Tetraazaisobacteriochlorins
	E.A. Makarova, E.A. Lukyanets. (Organic Intermediates and Dyes Institute, Moscow, Russia) lab31@co.ru

4-PO65	Tandem Reactions in the Synthesis оf Condensed 1,4-Diazines
	V.N. Charushin, P.A. Slepukhin, N.N. Mochulskaya, L.P. Sidorova, G.L. Rusinov, O.N. Chupakhin (Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia) charushin@ios.uran.ru

4-PO66	A New Approach to Condensed Pyrazines
	V.N. Charushin, A.M. Boguslavsky, M.G. Ponizovsky (Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia) charushin@ios.uran.ru

4-PO67	Fluorinated Derivatives of Azaheterocycles
	V.N. Charushin, E.V. Nosova, G.N. Lipunova (Ural Branch of the Russian Academy of Sciences, Ekaterinburg, Russia) charushin@ios.uran.ru

4-PO68	The C-C Coupling of Ferrocenes with Electron-deficient Azaaromatics – A New Route for Construction of Heterocyclic Ligands and Complexes
	O.N. Chupakhin, I.S. Kovalev, I.A. Utepova, V.L. Rusinov, V.N. Charushin, I. Postovsky (Ural Branch of the Russian Academy of Sciences, 620219, Ekaterinburg, Russia) charushin@ios.uran.ru

4-PO69	InBr₃Promoted Mukaiyama-Michael Reaction of Silyl Enol Ethers with 1,2-Diaza-1,3-Butadienes
	O. A. Attanasi, L. De Crescentini, G. Favi, P. Filippone, S. Lillini, F. Mantellini, S. Santeusanio (University of Urbino, Italy) attanasi@uniurb.it

4-PO70	Palladium (II)-Catalyzed Stereocontrolled Heterocyclization and Synthesis of 5-Epi-prelactone C
	M. Miyazawa, M. Narantsetseg, Y. Hirai (Toyama University, Japan) hirai@sci.toyama- u.ac.jp

4-PO71	Dihetarylethenes as Biologically Active Compounds and Photo-chromes for Optical Memory
	M.M. Krayushkin, M. Irie, V.A. Barachevsky (Russian Academy of Sciences, Moscow, Russia) mkray@ioc.ac.ru

4-PO72	Cyclic Sulfamidates as Versatile Intermediates for N-Heterocycle Construction. A Total Synthesis of (-)-Aphanorphine
	T. Gallagher, J.F. Bower (University of Bristol,UK) jb9663@bris.ac.uk

4-PO73	Potassium Aluminum Sulfate( Alum): an Efficient Catalyst for One-pot Synthesis of Di-hydropyrimidinones Under Microwave Irradiation
	Ali A. Mohammadi, Javad Azizian (Islamic Azad University, Sabzevar, Iran) Aliamohammadi@yahoo.com

4-PO74	Synthesis of Novel Pyperidyl Substituted 8-Azahypoxanthines
	Sergey V. Gozun, Constantine V. Kuleshov, Oleg G. Rodin, Valery P. Perevalov (Asinex Ltd., Moscow, Russia) labs@asinex.com

4-PO75	Synthesis of New 5-Phenyl-4,7-dihydro-1-thia-3b,6,7-triaza-cyclo-penta[a]azulene-8-one and its Properties
	Petr V. Davidenko, Denis N. Kazyulkin, Oleg G. Rodin, Mikhail A. Kirpichenok (Asinex Ltd., Moscow, Russia) pdavidenko@asinex.com

4-PO76	Macrolide-non-steroidal Antiinflammatory Drug Conjugates
	S. Selmani, M. Komac, O. Makaruha Stegić, V. Poljak, G. Šijan, S. Marković, M. Mesić, L. Tomašković, B. Hrvačić, M. Merćep (PLIVA Research Institute Ltd., Zagreb, Croatia) selvira.selmani@pliva.hr

4-PO77	4-Hydroxycoumarin Derivatives as Potential Anti-inflammatory Agents
	I.J. Elenkov, A.F. Sučić, M. Mesić, L. Lerman, A. Čempuh Klonkay, I. Malnar, B. Hrvačić, S. Marković, M. Merćep (PLIVA Research Institute Ltd., Zagreb, Croatia) anita.filipovic@pliva.hr

4-PO78	Synthesis of Some New Imidazole Derivatives from Ketimines
	M. Fodili, B.Nedjar-Kolli (Université des Sciences et de la Technologie Houari Boumédiène, Algiers, Algeria) Bellara_kollidz@yahoo.fr

4-PO79	The Molecular Structure and Conformational Study of 1,2-; 1,3- and 1,4- Dithiepane by ab Initio and DFT Calculations
	M. Haghdadi, M. Hamzehluiyan (Islamic Azad University, Babol, Iran) haghdadim@yahoo.com

4-PO80	Metallation Reactions of 2,3-Dihydrobenzothiophene Derivatives
	S. Cabiddu, E. Cadoni, S. De Montis, M. Usai, C. Fattuoni, M.G. Cabiddu (University of Cagliari, Italy) mikiusai@hotmail.com

4-PO81	Use of the Furoxan (1,2,5-Oxadiazole 2-oxide) System in the Design of New NO-donor Antioxidant Hybrids
	C. Cena, M. Bertinaria, D. Boschi, M. Giorgis, A. Gasco (University of Torino, Italy) clara.cena@unito.it

4-PO82	Fe/AcOH Promoted Sequential Processes of Aromatic Nitro Intermediates. A Convenient Route to Polycyclic Bioactive Systems
	F. Mingoia, M.L. Testa. (Istituto per lo Studio dei Materiali Nanostrutturati-CNR, Palermo, Italy) mingoia@pa.ismn.cnr.it

4-PO83	Studies on Enaminones: Synthesis and Chemical Reactivity of 4-Dimethylamino-3-phenyl-but-3-en-2-one
	F.A. Haleem M. Hussein, I.S. Abdel Hafiz, E.A. Ishak, M.H. Elnagdi, A.A. Atalla (Al Azhar University, Assiut 715, Egypt) haleemmh@hotmail.com

4-PO84	3-(2-Pyridyl)-[1,2,3]triazolo[1,5-a]pyridines. An Experimental and Theoretical (DFT) Study of the Ring-chain Isomerization
	B. Abarca, I. Alkorta, R. Ballesteros, F. Blanco,M. Chadlaoui,J. Elguero,F. Mojarrad(Universidad de Valencia, Burjassot, Spain) Belen.Abarca@uv.es

4-PO85	Oxidative Cyclization of Thiobenzanilides to Benzothiazoles Using N-Benzyl-DABCO Tribromide Under Mild Conditions
	F.M. Moghaddam, H. Zali-Boeini (University of Technology, Tehran, Iran) hzaliboinee@yahoo.com

4-PO86	Solid-supported Microwave-assisted Thio-claisen Rearrangment of Aryl Thioamides to tri-Substituted Thiophenes
	F.M. Moghaddam, H. Zali-Boeini, D. Zargarani (University of Technology, Tehran, Iran) hzaliboinee@yahoo.com

4-PO87	A Rapid and One-Step Synthesis of 4-Amino-2, 5-diarylthiazoles
	F.M. Moghaddam, H. Zali-Boeini, D. Zargarani (University of Technology, Tehran, Iran) hzaliboinee@yahoo.com

4-PO88	Synthesis, Characterization and Crystal Structure of the Dimeric Silver(I) Complex Containing 4-Amino-5-methyl-2H-1,2,4-triazole-3(4H)-thione
	Tahereh Sharafi (Alzahra University, Tehran, Iran) t_sharafi@alzahara.ac.ir

4-PO89	Synthesis, Characterization and Crystal Structures of New Palladium(II) Complexes and the First Platinum(III) Complex Containing ATT 6-Aza-2-thiothymine
	M.Ghassemzadeh, B. Neumüller (Chemistry & Chemical Engineering Research Center of Iran, Tehran, Iran) mghassemzadeh@ccerci.ac.ir

4-PO90	HIV-1 Protease Inhibitors and Resistance Induced by Mutation. Correlation between Multivariate Analysis and Molecular Docking
	A.M. Almerico, A. Lauria, M. Tutone, P. Diana, P. Barraja, A. Montalbano, G. Cirrincione, G. Dattolo (Università di Palermo, Italy) mtutone@unipa.it

4-PO91	The Preparation of Some Novel Indazole Derivatives by Using Chalcones
	J. Safaei-Ghomi, Z. Alishahi(University of Kashan, Iran) safaei@kashanu.ac.ir

4-PO92	Solvent Free Regioselective Cyclization of 3-Allylmercapto-1,2,4-Triazoles to Thiazolo[3,2-B]1,2,4-Triazoles over Sulfuric Acid Adsorbed on Silica Gel
	Shahnaz Khaleghi (Azzahra University, Tehran, Iran) khaleghi@alzahra.ac.ir

4-PO93	Synthesis of the AEFG-Macrolactam Portion of Diazonamide A: Highly Stereoselective Formation of the Key C10 Chiral Center via Aryllead(IV) Reagents
	J. Lin, B.S. Gerstenberger, J.P. Konopelski. (University of California, Santa Cruz, USA) joek@chemistry.ucsc.edu

4-PO94	Oxidation of 2-Hydroxynaphthaldehyde Hydrazones with NBS
	T. Liaskopoulos, N. Karousis, S. Skoulika, A.C. Tsipis, P.G. Tsoungas, G. Varvounis (University of Ioannina, Greece)gvarvoun@cc.uoi.gr

4B-OC21

N-Formylpyrrolidine Derivatives for Enantioselective Reduction of Aromatic Ketones Using Trichlorosilane

4-PO87

A Rapid and One-Step Synthesis of 4-Amino-2, 5-diarylthiazoles

4-PO92

Solvent Free Regioselective Cyclization of 3-Allylmercapto-1,2,4-Triazoles to Thiazolo[3,2-B]1,2,4-Triazoles over Sulfuric Acid Adsorbed on Silica Gel

Shahnaz Khaleghi (Azzahra University, Tehran, Iran) khaleghi@alzahra.ac.ir