CH3716 Quantitative Aspects of Medicinal Chemistry

Academic year

2024 to 2025 Semester 1

Further information on which modules are specific to your programme.

Key module information

SCOTCAT credits

10

The Scottish Credit Accumulation and Transfer (SCOTCAT) system allows credits gained in Scotland to be transferred between institutions. The number of credits associated with a module gives an indication of the amount of learning effort required by the learner. European Credit Transfer System (ECTS) credits are half the value of SCOTCAT credits.

SCQF level

SCQF level 9

The Scottish Credit and Qualifications Framework (SCQF) provides an indication of the complexity of award qualifications and associated learning and operates on an ascending numeric scale from Levels 1-12 with SCQF Level 10 equating to a Scottish undergraduate Honours degree.

Planned timetable

To be arranged.

This information is given as indicative. Timetable may change at short notice depending on room availability.

Module coordinator

Dr T Van Mourik

This information is given as indicative. Staff involved in a module may change at short notice depending on availability and circumstances.

Module Staff

Dr T van Mourik, Prof P A Wright, Prof T Smith

This information is given as indicative. Staff involved in a module may change at short notice depending on availability and circumstances.

Module description

The aim of the module is to cover some of the quantitative aspects of Medicinal Chemistry and drug design. Initially some relevant fundamental thermodynamics will be discussed. The thermodynamics of the drug receptor interactions will then be covered along with other aspects of pharmacology. The pharmacokinetic phase of drug action will be described including the absorption, distribution, metabolism and elimination (ADME) of drugs. The use of computational chemistry in the modern drug design process will then be discussed, covering force field calculations, molecular docking, QSAR and virtual screening.

Relationship to other modules

Pre-requisites

BEFORE TAKING THIS MODULE YOU MUST PASS 2 MODULES FROM {CH2501, CH2601, CH2701}

Anti-requisites

YOU CANNOT TAKE THIS MODULE IF YOU TAKE CH3717

Assessment pattern

2-hour Written Examination = 100%

Re-assessment

Oral Re-assessment = 100%

Learning and teaching methods and delivery

Weekly contact

1 - 3 lectures per week over 9 - 10 weeks (within Weeks 1-11) and 2-3 tutorials in total.

Scheduled learning hours

17

The number of compulsory student:staff contact hours over the period of the module.

Guided independent study hours

83

The number of hours that students are expected to invest in independent study over the period of the module.

Intended learning outcomes

  • Be familiar with quantitative aspects of medicinal chemistry and drug design.
  • Be familiar with thermodynamic concepts relevant to solutions
  • Be able to apply thermodynamic concepts relevant to solutions to biochemically important phenomena
  • Be familiar with computational chemistry techniques that are used in modern drug design processes
  • Be familiar with the use of computational chemistry in the design and development of drugs