Paramagnetic resonance for structural biology

Group leader: Bela Bode

Academic

Research overview

Stable radicals are being increasingly utilised in magnetic resonance spectroscopy. The covalent attachment of nitroxide spin probes allows reporting on the local environment. In doubly labelled systems the large dipolar interaction between the electron spins gives access to long range distance measurements. We seek to extend these methods to new spin probes and to multiply labelled systems by studying well defined model systems in parallel to biomolecular applications.

Publications

Vantourout, JC, Li, L, Bendito-Moll, E, Chabbra, S, Arrington, K, Bode, BE, Isidro-Llobet, A, Kowalski, JA, Nilson, MG, Wheelhouse, KMP, Woodard, JL, Xie, S, Leitch, DC & Watson, AJB 2018, 'Mechanistic insight enables practical, scalable, room temperature Chan–Lam N-arylation of N-aryl sulfonamides' ACS Catalysis, vol. 8, pp. 9560-9566. https://doi.org/10.1021/acscatal.8b03238

Overview

Overview header image

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences. The BSRC is grateful for funding from all funding agencies including the Institutional Strategic Support Fund from the Wellcome Trust.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research areas

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research by academic schools

Research in the BSRC is conducted by thirty-two independent research groups based in the Schools of Biology, Chemistry, Physics and Astronomy, and Medicine. Follow the links on the left to view groups associated with each school.