Synthetic methodology development and reaction asymmetry

Group leader: Andrew Smith

Royal Society University Research Fellow

Research overview

The ability to synthetically manipulate and prepare specific molecular structures with defined bespoke properties is the main goal of synthetic chemistry and catalysis, with applications that span the breadth of contemporary science ranging from materials chemistry to chemical biology. Catalysis provides society with efficient industrial processes that minimise energy, waste and harmful by-products. Andy’s research uses heterocyclic compounds as organocatalysts to develop new routes to prepare stereodefined materials from simple building blocks. Within this remit, our research speciality focuses upon the development of novel catalytic reaction processes using enantiopure heterocyclic Lewis base catalysts (isothioureas and N-heterocyclic carbenes), while simultaneously advancing a comprehensive mechanistic understanding of these transformations. In all projects the reactivity of heterocycles is used to discover novel approaches to the assembly of functional molecules.

For more information see the ADS Group Website: http://chemistry.st-and.ac.uk/staff/ads/group/

Publications

Overview

Overview header image

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences. The BSRC is grateful for funding from all funding agencies including the Institutional Strategic Support Fund from the Wellcome Trust.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research areas

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research by academic schools

Research in the BSRC is conducted by thirty-two independent research groups based in the Schools of Biology, Chemistry, Physics and Astronomy, and Medicine. Follow the links on the left to view groups associated with each school.