Molecular and structural biology

Group leader: Huanting Liu

Group Leader in BSRC

Publications

Hageluken, G, Clarke, BR , Huang, H , Tuukkanen, A, Danciu, I, Svergun, DI, Hussain, R, Liu, H, Whitfield, C & Naismith, JH 2015, ' A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide ' Nature Structural and Molecular Biology , vol 22, no. 1, pp. 50-56.
Houssen, WE, Bent, AF, McEwan, AR, Pieiller, N, Tabudravu, J , Koehnke, J , Mann, G, Adaba, RI, Thomas, L, Hawas, UW, Liu, H , Schwarz-Linek, U , Smith, MCM , Naismith, JH & Jaspars, M 2014, ' An efficient method for the in vitro production of Azol(in)e-based cyclic peptides ' Angewandte Chemie International Edition , vol 53, no. 51, pp. 14171-14174.
Reeks, J, Sokolowski, RD, Graham, S, Liu, H , Naismith, JH & White, MF 2013, ' Structure of a dimeric crenarchaeal Cas6 enzyme with an atypical active site for CRISPR RNA processing ' Biochemical Journal , vol 452, no. 2, pp. 223-230.
Reeks, JA, Graham, S, Anderson, L, Liu, H , White, MF & Naismith, J 2013, ' Structure of the archaeal Cascade subunit Csa5: Relating the small subunits of CRISPR effector complexes ' RNA Biology , vol 10, no. 5, pp. 762-769.
Moynie, L , Schnell, R, McMahon, SA, Sandalova, T, Abdelli Boulkeroua, W, Schmidberger, JW , Alphey, M , Cukier, C, Duthie, F, Kopec, J, Liu, H, Jacewicz, A, Hunter, WN , Naismith, JH & Schneider, G 2013, ' The AEROPATH project targeting Pseudomonas aeruginosa: crystallographic studies for assessment of potential targets in early-stage drug discovery ' Acta Crystallographica. Section F, Structural biology and crystallization communications , vol 69, no. 1, pp. 25-34.

Overview

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences. The BSRC is grateful for funding from all funding agencies including the Institutional Strategic Support Fund from the Wellcome Trust

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research areas

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research by academic schools

Research in the BSRC is conducted by thirty-two independent research groups based in the Schools of Biology, Chemistry, Physics and Astronomy, and Medicine. Follow the links on the left to view groups associated with each school.