Molecular and structural biology

Group leader: Huanting Liu

Group Leader in BSRC

Publications

Yang, J, Wang, Y, Wang, T, Jiang, J, Botting, CH, Liu, H, Chen, Q, Yang, J, Naismith, JH, Zhu, X & Chen, L 2016, 'Pironetin reacts covalently with cysteine-316 of α-tubulin to destabilize microtubule' Nature Communications, vol 7, 12103. DOI: 10.1038/ncomms12103
Juárez, JF, Liu, H, Zamarro, MT, McMahon, S, Liu, H, Naismith, J, Eberlein, C, Boll, M, Carmona, M & Diaz, E 2015, 'Unraveling the specific regulation of the mdb central pathway for the anaerobic degradation of 3-methylbenzoate' Journal of Biological Chemistry, vol 290, pp. 12165-12183. DOI: 10.1074/jbc.M115.637074
Hageluken, G, Clarke, BR, Huang, H, Tuukkanen, A, Danciu, I, Svergun, DI, Hussain, R, Liu, H, Whitfield, C & Naismith, JH 2015, 'A coiled-coil domain acts as a molecular ruler to regulate O-antigen chain length in lipopolysaccharide' Nature Structural and Molecular Biology, vol 22, no. 1, pp. 50-56. DOI: 10.1038/nsmb.2935
Houssen, WE, Bent, AF, McEwan, AR, Pieiller, N, Tabudravu, J, Koehnke, J, Mann, G, Adaba, RI, Thomas, L, Hawas, UW, Liu, H, Schwarz-Linek, U, Smith, MCM, Naismith, JH & Jaspars, M 2014, 'An efficient method for the in vitro production of Azol(in)e-based cyclic peptides' Angewandte Chemie International Edition, vol 53, no. 51, pp. 14171-14174. DOI: 10.1002/anie.201408082

Overview

Overview header image

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences. The BSRC is grateful for funding from all funding agencies including the Institutional Strategic Support Fund from the Wellcome Trust.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research areas

Scientists associated with the thirty-two research groups that are affiliated with the Biomedical Sciences Research Complex perform highly innovative, multi-disciplinary research in eleven broad areas of biomedical research, employing state-of-the-art techniques to address key questions at the leading edge of the biomedical and biological sciences.

Follow the links on the left to view individual research groups associated with one or more of the eleven BSRC research areas.

Research by academic schools

Research in the BSRC is conducted by thirty-two independent research groups based in the Schools of Biology, Chemistry, Physics and Astronomy, and Medicine. Follow the links on the left to view groups associated with each school.