Mr Dan Young
Senior Technical Specialist
Selected publications
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Open access
Persistent paramyxovirus infections: in co-infections the parainfluenza virus type 5 persistent phenotype is dominant over the lytic phenotype
Randall, R. E., Young, D. F., Hughes, D. J. & Goodbourn, S., 14 Nov 2023, In: Journal of General Virology. 104, 11, 13 p., 001916.Research output: Contribution to journal › Article › peer-review
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Open access
Organic light-emitting diode based fluorescence-linked immunosorbent assay for SARS-CoV-2 antibody detection
Lian, C., Young, D. F., Randall, R. E. & Samuel, I. D. W., 5 Dec 2022, In: Biosensors. 12, 12, 13 p., 1125.Research output: Contribution to journal › Article › peer-review
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Open access
Partial human Janus kinase 1 deficiency predominantly impairs responses to interferon gamma and intracellular control of mycobacteria
Daza-Cajigal, V., Albuquerque, A. S., Young, D. F., Ciancanelli, M. J., Moulding, D., Angulo, I., Jeanne-Julien, V., Rosain, J., Minskaia, E., Casanova, J.-L., Boisson-Dupuis, S., Bustamante, J., Randall, R. E., McHugh, T. D., Thrasher, A. J. & Burns, S. O., 9 Sept 2022, In: Frontiers in Immunology. 13, 14 p., 888427.Research output: Contribution to journal › Article › peer-review
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Open access
Innate intracellular antiviral responses restrict the amplification of defective virus genomes of parainfluenza virus type 5
Wignall-Fleming, E. B., Vasou, A., Young, D., Short, J. A. L., Hughes, D. J., Goodbourn, S. & Randall, R. E., 16 Jun 2020, (E-pub ahead of print) In: Journal of Virology. 94, 13, 15 p., 00246-20.Research output: Contribution to journal › Article › peer-review
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Severe type I interferonopathy and unrestrained interferon signaling due to a homozygous germline mutation in STAT2
Duncan, C. J. A., Thompson, B. J., Chen, R., Rice, G. I., Gothe, F., Young, D. F., Lovell, S. C., Shuttleworth, V. G., Brocklebank, V., Corner, B., Skelton, A. J., Bondet, V., Coxhead, J., Duffy, D., Fourrage, C., Livingston, J. H., Pavaine, J., Cheesman, E., Bitetti, S. & Grainger, A. & 18 others, , 13 Dec 2019, In: Science Immunology. 4, 42, eaav7501.Research output: Contribution to journal › Article › peer-review
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Open access
The switch between acute and persistent paramyxovirus infection caused by single amino acid substitutions in the RNA polymerase P subunit
Young, D. F., Wignall-Fleming, E. B., Busse, D. C., Pickin, M. J., Hankinson, J., Randall, E. M., Tavendale, A., Davison, A. J., Lamont, D., Tregoning, J. S., Goodbourn, S. & Randall, R. E., 11 Feb 2019, In: PLoS Pathogens. 15, 2, 24 p., e1007561.Research output: Contribution to journal › Article › peer-review
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Open access
Genome sequence of the parainfluenza virus 5 strain that persistently infects AGS cells
Wignall-Fleming, E., Young, D. F., Goodburn, S., Davison, A. J. & Randall, R. E., 21 Jul 2016, In: Genome Announcements. 4, 4, 2 p., e00653-16.Research output: Contribution to journal › Article › peer-review
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Open access
Human IFIT1 inhibits mRNA translation of rubulaviruses but not other members of the Paramyxoviridae family
Young, D. F., Andrejeva, J., Li, X., Inesta-Vaquera, F., Dong, C., Cowling, V. H., Goodbourn, S. & Randall, R. E., Oct 2016, In: Journal of Virology. 90, 20, p. 9446-9456Research output: Contribution to journal › Article › peer-review
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Open access
Human IFNAR2 deficiency: lessons for antiviral immunity
Duncan, C. J. A., Mohamad, S. M. B., Young, D. F., Skelton, A. J., Leahy, T. R., Munday, D. C., Butler, K. M., Morfopoulou, S., Brown, J. R., Hubank, M., Connell, J., Gavin, P. J., McMahon, C., Dempsey, E., Lynch, N. E., Jacques, T. S., Valappil, M., Cant, A. J., Breuer, J. & Engelhardt, K. R. & 2 others, , 30 Sept 2015, In: Science Translational Medicine. 7, 307, 7 p., 307ra154.Research output: Contribution to journal › Article › peer-review
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Open access
Deep sequencing analysis of defective genomes of parainfluenza virus 5 and their role in interferon induction
Killip, M. J., Young, D. F., Gatherer, D., Ross, C. S., Short, J. A. L., Davison, A. J., Goodbourn, S. & Randall, R. E., May 2013, In: Journal of Virology. 87, 9, p. 4798-4807 10 p.Research output: Contribution to journal › Article › peer-review